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Searching for up to 100 curated homologs for CCNA_01843 FitnessBrowser__Caulo:CCNA_01843 (525 a.a.)

Found high-coverage hits (≥70%) to 69 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

3cuxA / A0A6L8PPD0 Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design (see paper)
    57% identity, 98% coverage of query (608 bits)

BPHYT_RS12305 Malate synthase (EC 2.3.3.9) from Burkholderia phytofirmans PsJN
    53% identity, 99% coverage of query (569 bits)

SO1483 Malate synthase (EC 2.3.3.9) from Shewanella oneidensis MR-1
    54% identity, 96% coverage of query (553 bits)

3cuzA / P08997 Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design (see paper)
    54% identity, 98% coverage of query (553 bits)

3cv1A Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design
    54% identity, 98% coverage of query (553 bits)

Mas / b4014 malate synthase A (EC 2.3.3.9) from Escherichia coli K-12 substr. MG1655 (see 14 papers)
aceB / P08997 malate synthase A (EC 2.3.3.9) from Escherichia coli (strain K12) (see 15 papers)
    54% identity, 98% coverage of query (552 bits)

3cv2A Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design
    54% identity, 98% coverage of query (552 bits)

CH_124037 putative malate synthase [Candida tropicalis] from Magnaporthe grisea 70-15 (see paper)
    52% identity, 99% coverage of query (546 bits)

GCP_CAEEL / Q10663 Bifunctional glyoxylate cycle protein; Gex-3-interacting protein 7; EC 4.1.3.1; EC 2.3.3.9 from Caenorhabditis elegans (see 2 papers)
    53% identity, 96% coverage of query (543 bits)

MASY_DICDI / Q8T2K9 Malate synthase; EC 2.3.3.9 from Dictyostelium discoideum (Social amoeba) (see paper)
    49% identity, 98% coverage of query (540 bits)

Q5YLB8 malate synthase (EC 2.3.3.9) from Paracoccidioides brasiliensis (see 2 papers)
    51% identity, 98% coverage of query (530 bits)

Q9ZH77 malate synthase (EC 2.3.3.9) from Streptomyces clavuligerus (see paper)
    52% identity, 98% coverage of query (520 bits)

MLS / Q9LZC3 malate synthase (EC 2.3.3.9) from Arabidopsis thaliana (see paper)
MASY_ARATH / Q9LZC3 Malate synthase; EC 2.3.3.9 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    50% identity, 96% coverage of query (512 bits)

acuE malate synthase; EC 2.3.3.9 from Emericella nidulans (see 5 papers)
    50% identity, 98% coverage of query (504 bits)

MLS1 malate synthase; EC 2.3.3.9 from Candida albicans (see paper)
    48% identity, 99% coverage of query (498 bits)

CAA40262.1 malate synthase from Cucurbita hybrid cultivar (see paper)
    48% identity, 99% coverage of query (497 bits)

MASY_ORYSJ / Q7XUG1 Malate synthase; EC 2.3.3.9 from Oryza sativa subsp. japonica (Rice) (see paper)
    50% identity, 99% coverage of query (492 bits)

MLS1 / P30952 malate synthase (EC 2.3.3.7; EC 2.3.3.9) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
MLS1_YEAST / P30952 Malate synthase 1; EC 2.3.3.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    47% identity, 97% coverage of query (488 bits)

DAL7 / P21826 malate synthase 2 (EC 2.3.3.7; EC 2.3.3.9) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
MLS2_YEAST / P21826 Malate synthase 2; Degradation of allantoin protein 7; EC 2.3.3.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
    46% identity, 97% coverage of query (471 bits)

Build an alignment

Build an alignment for CCNA_01843 and 19 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

MASZ_MYCLB / B8ZSN3 Malate synthase G; EC 2.3.3.9 from Mycobacterium leprae (strain Br4923)
    24% identity, 80% coverage of query (53.9 bits)

5cahA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 6h-thieno[2,3-b]pyrrole-5-carboxylic acid
    24% identity, 72% coverage of query (52.8 bits)

4ex4B / B8ZSN3 The structure of glcb from mycobacterium leprae
    26% identity, 75% coverage of query (51.6 bits)

4ex4A / B8ZSN3 The structure of glcb from mycobacterium leprae
    24% identity, 81% coverage of query (51.2 bits)

6axbA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-naphthyldiketoacid
    22% identity, 79% coverage of query (50.4 bits)

3s9zA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4-(2-bromophenyl)-2,4-dioxobutanoic acid inhibitor
    22% identity, 79% coverage of query (50.4 bits)

3s9iA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-4-dioxo-4-phenylbutanoic acid inhibitor
    23% identity, 79% coverage of query (50.1 bits)

5cjmA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4h-thieno[3,2-b]pyrrole-5-carboxylic acid
    24% identity, 72% coverage of query (49.7 bits)

5cc6A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 1h-indole-5-carboxylic acid
    24% identity, 72% coverage of query (49.7 bits)

5cc7A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 1h-indole-6-carboxylic acid
    24% identity, 72% coverage of query (49.7 bits)

1n8iA Biochemical and structural studies of malate synthase from mycobacterium tuberculosis
    24% identity, 72% coverage of query (49.3 bits)

5e9xA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-chloro-6h-thieno[2,3-b]pyrrole-5-carboxylic acid
    22% identity, 72% coverage of query (48.9 bits)

3sb0A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4-(2-chloro-6-fluoro-3-methylphenyl)-2,4-dioxobutanoic acid inhibitor
    24% identity, 72% coverage of query (48.9 bits)

6c7bA Crystal structure of mycobacterium tuberculosis malate synthase in complex with methoxynaphthyldiketoacid
    24% identity, 72% coverage of query (48.9 bits)

5ecvA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-4-(4-methyl-1h-indol-5-yl)-4-oxobut-2-enoic acid
    23% identity, 72% coverage of query (48.9 bits)

6c2xA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-br-6-me-phenyldiketoacid
    24% identity, 72% coverage of query (48.9 bits)

5cczA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 3-(4-fluorophenyl)-4-methyl-1h-pyrazol-5-amine
    23% identity, 72% coverage of query (48.9 bits)

6dljA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-nitro-phenyldiketoacid
    24% identity, 72% coverage of query (48.9 bits)

6dl9A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2,6-cl-phenyldiketoacid
    23% identity, 72% coverage of query (48.9 bits)

5c9xA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2,4-dichloro-5-fluorobenzoic acid
    23% identity, 72% coverage of query (48.9 bits)

5c7vA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 1h-pyrrole-2-carboxylic acid
    23% identity, 72% coverage of query (48.9 bits)

6apzA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 3-hydroxy-phenyldiketoacid
    24% identity, 72% coverage of query (48.9 bits)

6dnpA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-f-3-methyl-6-f-phenyldiketoacid
    24% identity, 72% coverage of query (48.5 bits)

6bu1A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-br-3-oh-phenyldiketoacid
    24% identity, 72% coverage of query (48.5 bits)

6c6oA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-br-4-oh-phenyldiketoacid
    24% identity, 72% coverage of query (48.5 bits)

5drcA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-4-(1h-indol-3-yl)-4-oxobut-2-enoic acid
    23% identity, 72% coverage of query (48.5 bits)

6au9A Crystal structure of mycobacterium tuberculosis malate synthase in complex with dioxine-phenyldiketoacid
    23% identity, 72% coverage of query (48.5 bits)

5cbbA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 5-(3h-indol-3-ylidene)-2,5-dihydro-1h-pyrazole-3- carboxylate
    23% identity, 72% coverage of query (48.5 bits)

6as6A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 3-prop-6-me-phenyldiketoacid
    24% identity, 72% coverage of query (48.5 bits)

5cakA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-3-(1h-indol-3-yl)propanoic acid
    23% identity, 72% coverage of query (48.5 bits)

5c9wA Crystal structure of mycobacterium tuberculosis malate synthase in complex with (z)-n-(2-bromophenyl)-2-(hydroxyimino)acetamide
    24% identity, 72% coverage of query (48.5 bits)

5cbjA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 3-(phenylthio)acrylic acid
    24% identity, 72% coverage of query (48.5 bits)

5t8gA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-oxo-4-((thiophene-2-carbonyl)oxy)butanoic acid
    24% identity, 72% coverage of query (48.5 bits)

5dx7A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 5-(5-chlorothiophen-2-yl)isoxazole-3-carboxylic acid
    24% identity, 72% coverage of query (48.5 bits)

5cjnA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 3-(3-oxo-3,4-dihydroquinoxalin-2-yl)acrylate
    23% identity, 72% coverage of query (48.5 bits)

5c9uA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-(2-(2,4-dichlorophenyl)hydrazinyl)-2-oxoacetic acid
    24% identity, 72% coverage of query (48.5 bits)

5cbiA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 5-chloro-2-hydroxybenzonitrile
    23% identity, 72% coverage of query (48.1 bits)

5cewA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-(pyridin-4-yl)thiazolidine-4-carboxylic acid
    24% identity, 72% coverage of query (48.1 bits)

5cc5A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 1h-indole-3-carboxylic acid
    24% identity, 72% coverage of query (48.1 bits)

3sadA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4-(2-mehtylphenyl)-2,4-dioxobutanoic acid inhibitor
    24% identity, 72% coverage of query (48.1 bits)

3sazA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4-(3-bromophenyl)-2,4-dioxobutanoic acid inhibitor
    24% identity, 72% coverage of query (48.1 bits)

6ba7A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-cl-4-oh-phenyldiketoacid
    24% identity, 72% coverage of query (48.1 bits)

5cc3A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 6-bromo-1h-indole-2-carboxylic acid
    23% identity, 72% coverage of query (48.1 bits)

5driA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-4-(1h-indol-5-yl)-4-oxobut-2-enoic acid inhibitor
    23% identity, 72% coverage of query (47.8 bits)

glcB / P9WK17 malate synthase G (EC 2.3.3.9) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
MASZ_MYCTO / P9WK16 Malate synthase G; EC 2.3.3.9 from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see paper)
MASZ_MYCTU / P9WK17 Malate synthase G; EC 2.3.3.9 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P9WK17 malate synthase (EC 2.3.3.9) from Mycobacterium tuberculosis (see paper)
    23% identity, 72% coverage of query (47.4 bits)

6c8pA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-f-phenyldiketoacid
    23% identity, 72% coverage of query (47.4 bits)

6dkoA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2,6-f-phenyldiketoacid
    23% identity, 72% coverage of query (47.4 bits)

6asuA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4-methyl-phenyldiketoacid
    23% identity, 72% coverage of query (47.4 bits)

5c9rA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 3-((4-chlorophenyl)thio)propanoic acid
    23% identity, 72% coverage of query (47.0 bits)

2gq3A / P9WK17 Mycobacterium tuberculosis malate synthase in complex with magnesium, malate, and coenzyme a (see paper)
    23% identity, 72% coverage of query (45.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory