Searching for up to 100 curated homologs for CCNA_02250 FitnessBrowser__Caulo:CCNA_02250 (654 a.a.)
Found high-coverage hits (≥70%) to 44 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
SM_b21124 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Sinorhizobium meliloti 1021
53% identity, 99% coverage of query (613 bits)
MCCC1 / Q96RQ3 3-methylcrotonyl-CoA carboxylase α subunit (EC 6.4.1.4) from Homo sapiens (see 4 papers)
MCCA_HUMAN / Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Homo sapiens (Human) (see 15 papers)
47% identity, 99% coverage of query (555 bits)
MCCA_ARATH / Q42523 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q42523 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Arabidopsis thaliana (see 2 papers)
45% identity, 99% coverage of query (553 bits)
atuF / Q9HZV6 cis-geranyl-CoA carboxylase α-subunit (EC 6.4.1.5) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
46% identity, 99% coverage of query (525 bits)
MCCA_MOUSE / Q99MR8 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Mus musculus (Mouse) (see paper)
45% identity, 99% coverage of query (522 bits)
AO356_01595 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2C3
47% identity, 99% coverage of query (520 bits)
Pf6N2E2_2194 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2E2
47% identity, 99% coverage of query (514 bits)
ACCA1_MYCTU / P9WPQ3 Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit; EC 6.3.4.14 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
CAA79609.1 biotin carboxyl carrier protein from Mycobacterium tuberculosis (see paper)
47% identity, 99% coverage of query (510 bits)
Sama_1359 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Shewanella amazonensis SB2B
47% identity, 100% coverage of query (509 bits)
liuD / Q9I299 methylcrotonyl-CoA carboxylase α-subunit (EC 6.4.1.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I299 methylcrotonoyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.4) from Pseudomonas aeruginosa (see 3 papers)
49% identity, 99% coverage of query (506 bits)
Pf1N1B4_3984 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N1B4
47% identity, 100% coverage of query (505 bits)
mccA 3-methylcrotonyl-CoA carboxylase biotin-containig subunit; EC 6.4.1.4 from Emericella nidulans (see paper)
mccA / AAR23110.1 3-methylcrotonyl-CoA carboxylase biotin-containing subunit from Aspergillus nidulans (see paper)
46% identity, 96% coverage of query (491 bits)
Dsui_0516 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dechlorosoma suillum PS
44% identity, 99% coverage of query (487 bits)
pccA / Q3J4D9 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see paper)
51% identity, 71% coverage of query (449 bits)
PCCA_PIG / P0DTA4 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Sus scrofa (Pig) (see paper)
40% identity, 99% coverage of query (439 bits)
7ybuA / P05165 Human propionyl-coenzyme a carboxylase
40% identity, 99% coverage of query (433 bits)
PCCA / P05165 propionyl-CoA carboxylase α chain, mitochondrial (EC 6.4.1.3) from Homo sapiens (see 4 papers)
PCCA_HUMAN / P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Homo sapiens (Human) (see 11 papers)
P05165 propionyl-CoA carboxylase (subunit 1/2) (EC 6.4.1.3) from Homo sapiens (see paper)
40% identity, 99% coverage of query (432 bits)
PCCA_CAEEL / Q19842 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Caenorhabditis elegans (see paper)
Q19842 propionyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.3) from Caenorhabditis elegans (see paper)
40% identity, 99% coverage of query (426 bits)
8sgxX / A0A640KC69 Leishmania tarentolae propionyl-coa carboxylase (alpha-4-beta-6) (see paper)
38% identity, 99% coverage of query (419 bits)
PCCA_MOUSE / Q91ZA3 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Mus musculus (Mouse) (see paper)
38% identity, 99% coverage of query (415 bits)
Pcca / P14882 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Rattus norvegicus (see paper)
38% identity, 99% coverage of query (399 bits)
Q6CP22 allophanate hydrolase (EC 3.5.1.54); urea carboxylase (EC 6.3.4.6) from Kluyveromyces lactis (see 3 papers)
40% identity, 77% coverage of query (376 bits)
8hz4A / A9W9X0 The tetrameric structure of biotin carboxylase from chloroflexus aurantiacus in complex with bicarbonate
47% identity, 71% coverage of query (371 bits)
PYC_STAAM / A0A0H3JRU9 Pyruvate carboxylase; EC 6.4.1.1 from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see 3 papers)
A0A0H3JRU9 pyruvate carboxylase (EC 6.4.1.1) from Staphylococcus aureus (see 4 papers)
41% identity, 71% coverage of query (365 bits)
3tw6B / Q2K340 Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a (see paper)
39% identity, 76% coverage of query (360 bits)
3bg5A / A0A0H3JRU9 Crystal structure of staphylococcus aureus pyruvate carboxylase (see paper)
40% identity, 71% coverage of query (342 bits)
3hb9A Crystal structure of s. Aureus pyruvate carboxylase a610t mutant
39% identity, 71% coverage of query (331 bits)
3tw6C Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a
38% identity, 74% coverage of query (328 bits)
8gk8A R21a staphylococcus aureus pyruvate carboxylase
39% identity, 71% coverage of query (317 bits)
Build an alignment for CCNA_02250 and 29 homologs with ≥ 30% identity
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ACAC_YEAST / Q00955 Acetyl-CoA carboxylase; ACC; Fatty acid synthetase 3; mRNA transport-defective protein 7; EC 6.4.1.2; EC 6.3.4.14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
Q00955 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (EC 6.4.1.2) from Saccharomyces cerevisiae (see 6 papers)
28% identity, 99% coverage of query (240 bits)
3ho8A Crystal structure of s. Aureus pyruvate carboxylase in complex with coenzyme a
32% identity, 71% coverage of query (234 bits)
ACC1 / Q13085 acetyl-CoA carboxylase 1 (EC 2.1.3.15; EC 6.4.1.2; EC 6.3.4.14) from Homo sapiens (see 6 papers)
ACACA_HUMAN / Q13085 Acetyl-CoA carboxylase 1; ACC1; Acetyl-Coenzyme A carboxylase alpha; ACC-alpha; EC 6.4.1.2 from Homo sapiens (Human) (see 8 papers)
Q13085 acetyl-CoA carboxylase (EC 6.4.1.2) from Homo sapiens (see 13 papers)
28% identity, 99% coverage of query (230 bits)
5cslB / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
28% identity, 93% coverage of query (228 bits)
ACACA_MOUSE / Q5SWU9 Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; Acetyl-CoA carboxylase 265; EC 6.4.1.2 from Mus musculus (Mouse) (see 4 papers)
Q5SWU9 acetyl-CoA carboxylase (EC 6.4.1.2) from Mus musculus (see 2 papers)
28% identity, 99% coverage of query (228 bits)
3bg5B / A0A0H3JRU9 Crystal structure of staphylococcus aureus pyruvate carboxylase (see paper)
32% identity, 71% coverage of query (228 bits)
3ho8D / A0A0H3JRU9 Crystal structure of s. Aureus pyruvate carboxylase in complex with coenzyme a (see paper)
32% identity, 71% coverage of query (227 bits)
P11029 Acetyl-CoA carboxylase; ACC; EC 6.4.1.2; EC 6.3.4.14 from Gallus gallus (Chicken)
28% identity, 99% coverage of query (227 bits)
5cslA / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
27% identity, 99% coverage of query (220 bits)
ACACA_RAT / P11497 Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; EC 6.4.1.2 from Rattus norvegicus (Rat) (see 4 papers)
28% identity, 99% coverage of query (219 bits)
ACAC_SCHPO / P78820 Acetyl-CoA carboxylase; ACC; Cell untimely torn protein 6; EC 6.4.1.2; EC 6.3.4.14 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
cut6 / RF|NP_593271.1 acetyl-CoA/biotin carboxylase; EC 6.3.4.14 from Schizosaccharomyces pombe (see 2 papers)
28% identity, 99% coverage of query (218 bits)
8gk8C R21a staphylococcus aureus pyruvate carboxylase
32% identity, 71% coverage of query (217 bits)
ACACB_MOUSE / E9Q4Z2 Acetyl-CoA carboxylase 2; ACC-beta; EC 6.4.1.2 from Mus musculus (Mouse) (see 10 papers)
27% identity, 99% coverage of query (217 bits)
4hnvB / A0A0H3JRU9 Crystal structure of r54e mutant of s. Aureus pyruvate carboxylase (see paper)
29% identity, 71% coverage of query (184 bits)
8gk8D R21a staphylococcus aureus pyruvate carboxylase
28% identity, 71% coverage of query (167 bits)
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