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Searching for up to 100 curated homologs for CCNA_02751 CCNA_02751 ABC transporter ATP-binding protein (332 a.a.)

Found high-coverage hits (≥70%) to 59 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.24.5 / Q9HT70 Methionine import ATP-binding protein MetN 2, component of L-Histidine uptake porter, MetIQN from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    65% identity, 98% coverage of query (422 bits)

METN_BACSU / O32169 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.24.2 / O32169 MetN (C) (aka YusC), component of The L- and D-methionine porter (also transports methionine sulfoxide from Bacillus subtilis subsp. subtilis str. 168 (see 2 papers)
    51% identity, 93% coverage of query (322 bits)

MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
    49% identity, 98% coverage of query (308 bits)

6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
    48% identity, 98% coverage of query (306 bits)

3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
    48% identity, 98% coverage of query (306 bits)

3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
    48% identity, 98% coverage of query (306 bits)

TC 3.A.1.24.4 / Q8NSN2 Methionine import ATP-binding protein metN, component of L-Methionine uptake porter, MetQNI from Corynebacterium glutamicum (see paper)
    46% identity, 95% coverage of query (277 bits)

TC 3.A.1.24.3 / Q8K8K8 AtmD (MetN), component of The methionine porter, AtmBDE from Streptococcus pyogenes serotype M3 (see 2 papers)
    43% identity, 98% coverage of query (273 bits)

AO353_16275 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, ATPase component from Pseudomonas fluorescens FW300-N2E3
    48% identity, 72% coverage of query (211 bits)

Pf1N1B4_774 ABC transporter for L-asparagine and L-glutamate, ATPase component from Pseudomonas fluorescens FW300-N1B4
    47% identity, 73% coverage of query (210 bits)

4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
    47% identity, 72% coverage of query (209 bits)

YhdZ / b3271 putative ABC transporter ATP-binding subunit YhdZ from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yhdZ / RF|NP_417737 uncharacterized amino-acid ABC transporter ATP-binding protein yhdZ from Escherichia coli K12 (see 3 papers)
    43% identity, 73% coverage of query (207 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    45% identity, 72% coverage of query (205 bits)

GLUA_CORGL / P48243 Glutamate transport ATP-binding protein GluA; Glutamate uptake system protein GluA; EC 7.4.2.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 3.A.1.3.9 / P48243 GluA aka CGL1950, component of Glutamate porter from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
    46% identity, 72% coverage of query (200 bits)

ARTM_BACSU / P54537 Arginine transport ATP-binding protein ArtM from Bacillus subtilis (strain 168) (see paper)
    41% identity, 73% coverage of query (199 bits)

GLNQ_BACSU / O34677 Glutamine transport ATP-binding protein GlnQ; EC 7.4.2.- from Bacillus subtilis (strain 168) (see paper)
    43% identity, 72% coverage of query (199 bits)

TC 3.A.1.3.22 / Q9I405 Amino acid ABC transporter ATP binding protein, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    45% identity, 72% coverage of query (198 bits)

GltL / b0652 glutamate/aspartate ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see paper)
GltL / P0AAG3 glutamate/aspartate ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.4 / P0AAG3 Glutamate/aspartate transport ATP-binding protein GltL aka B0652, component of Glutamate/aspartate porter from Escherichia coli (see 3 papers)
    47% identity, 72% coverage of query (196 bits)

Pf6N2E2_5405 ABC transporter for D-Alanine, ATPase component from Pseudomonas fluorescens FW300-N2E2
    43% identity, 73% coverage of query (196 bits)

TC 3.A.1.3.5 / P0A2V2 Octopine permease ATP-binding protein P aka occP, component of Octopine porter from Agrobacterium tumefaciens (see 2 papers)
    43% identity, 72% coverage of query (196 bits)

AO356_05515 ABC transporter for L-Lysine, ATPase component from Pseudomonas fluorescens FW300-N2C3
    45% identity, 72% coverage of query (195 bits)

A0A077T7Z1 ABC-type quaternary amine transporter (subunit 1/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    43% identity, 71% coverage of query (195 bits)

TC 3.A.1.3.16 / A3ZI83 PEB1C, component of Uptake system for glutamate and aspartate from Campylobacter jejuni subsp. jejuni 84-25
    42% identity, 72% coverage of query (194 bits)

3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
    43% identity, 72% coverage of query (194 bits)

BPHYT_RS07685 ABC transporter for L-Arginine, putative ATPase component from Burkholderia phytofirmans PsJN
    45% identity, 72% coverage of query (194 bits)

3c4jA Abc protein artp in complex with atp-gamma-s
    43% identity, 72% coverage of query (194 bits)

2olkA Abc protein artp in complex with adp-beta-s
    43% identity, 72% coverage of query (194 bits)

2oljA Abc protein artp in complex with adp/mg2+
    43% identity, 72% coverage of query (194 bits)

Pf6N2E2_2962 ABC transporter for L-Lysine, ATPase component from Pseudomonas fluorescens FW300-N2E2
    45% identity, 72% coverage of query (192 bits)

TC 3.A.1.3.12 / P73721 BgtA aka SLR1735, component of Arginine/lysine/histidine/glutamine porter (see paper)
    45% identity, 72% coverage of query (192 bits)

SMc02121 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component from Sinorhizobium meliloti 1021
    41% identity, 72% coverage of query (191 bits)

HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
    47% identity, 71% coverage of query (184 bits)

1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
    47% identity, 71% coverage of query (184 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    35% identity, 74% coverage of query (159 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    35% identity, 74% coverage of query (159 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    35% identity, 74% coverage of query (159 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    33% identity, 72% coverage of query (145 bits)

5lilA / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atpys (p21) (see paper)
    36% identity, 73% coverage of query (144 bits)

5lj7A / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atp (p21) (see paper)
    36% identity, 73% coverage of query (144 bits)

1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
    34% identity, 74% coverage of query (142 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    34% identity, 71% coverage of query (137 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    34% identity, 71% coverage of query (137 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    34% identity, 71% coverage of query (136 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    36% identity, 72% coverage of query (134 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    36% identity, 72% coverage of query (134 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    36% identity, 72% coverage of query (134 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    36% identity, 72% coverage of query (134 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    36% identity, 72% coverage of query (134 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    36% identity, 72% coverage of query (134 bits)

1q12A Crystal structure of the atp-bound e. Coli malk
    36% identity, 72% coverage of query (133 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    36% identity, 72% coverage of query (133 bits)

5ws4A / A0A0D8G707 Crystal structure of tripartite-type abc transporter macb from acinetobacter baumannii (see paper)
    33% identity, 83% coverage of query (131 bits)

3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
    37% identity, 71% coverage of query (128 bits)

8f5bA / P78363 Human abca4 structure in complex with amp-pnp
    30% identity, 74% coverage of query (120 bits)

6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
    34% identity, 78% coverage of query (120 bits)

3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    34% identity, 78% coverage of query (120 bits)

3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    34% identity, 78% coverage of query (120 bits)

6c0vA Molecular structure of human p-glycoprotein in the atp-bound, outward- facing conformation
    33% identity, 75% coverage of query (119 bits)

8eopA / Q8IZY2 Cryo-em structure of nanodisc reconstituted human abca7 eq mutant in atp bound closed state (see paper)
    31% identity, 71% coverage of query (108 bits)

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Build an alignment for CCNA_02751 and 59 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory