Searching for up to 100 curated homologs for CCNA_02881 FitnessBrowser__Caulo:CCNA_02881 (528 a.a.)
Found high-coverage hits (≥70%) to 50 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
KGSD3_AZOBR / Q08IB7 Alpha-ketoglutaric semialdehyde dehydrogenase 3; alphaKGSA dehydrogenase 3; 2,5-dioxovalerate dehydrogenase 3; KGSADH-III; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IB7 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
66% identity, 99% coverage of query (632 bits)
lhpG / Q88NF5 α-ketoglutaric semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
62% identity, 98% coverage of query (590 bits)
KGSD2_AZOBR / Q08IC0 Alpha-ketoglutaric semialdehyde dehydrogenase 2; alphaKGSA dehydrogenase 2; 2,5-dioxovalerate dehydrogenase 2; KGSADH-II; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IC0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
61% identity, 99% coverage of query (573 bits)
Ga0059261_1896 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Sphingomonas koreensis DSMZ 15582
61% identity, 99% coverage of query (571 bits)
kgsD / Q9I1Q0 2-ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
50% identity, 99% coverage of query (457 bits)
ACIAD0131 / Q6FFQ0 α-ketoglutarate semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
KGSDH_ACIAD / Q6FFQ0 Alpha-ketoglutaric semialdehyde dehydrogenase; alphaKGSA dehydrogenase; 2,5-dioxovalerate dehydrogenase; EC 1.2.1.26 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Acinetobacter baylyi (see paper)
48% identity, 99% coverage of query (454 bits)
HSERO_RS00735 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Herbaspirillum seropedicae SmR1
50% identity, 99% coverage of query (453 bits)
Pf6N2E2_612 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas fluorescens FW300-N2E2
49% identity, 99% coverage of query (449 bits)
PS417_11015 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas simiae WCS417
49% identity, 99% coverage of query (448 bits)
aldH / AAA89078.1 fatty aldehyde dehydrogenase from Vibrio harveyi (see paper)
47% identity, 95% coverage of query (436 bits)
1eyyA / Q56694 Crystal structure of the NADP+ dependent aldehyde dehydrogenase from vibrio harveyi. (see paper)
47% identity, 95% coverage of query (436 bits)
Q88GW5 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Pseudomonas putida (see paper)
47% identity, 100% coverage of query (430 bits)
Build an alignment for CCNA_02881 and 12 homologs with ≥ 30% identity
Or download the sequences
SO0619 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) from Shewanella oneidensis MR-1
28% identity, 76% coverage of query (82.8 bits)
padA / CAA66106.1 phenylacetaldehyde dehydrogenase from Escherichia coli (see paper)
27% identity, 84% coverage of query (81.3 bits)
putA / Q88D80 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88; EC 1.5.5.2) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 11 papers)
27% identity, 81% coverage of query (80.1 bits)
Ac3H11_612 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Acidovorax sp. GW101-3H11
28% identity, 76% coverage of query (79.7 bits)
YdbG / b1385 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
feaB / P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (strain K12) (see 10 papers)
P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (see 3 papers)
27% identity, 84% coverage of query (78.6 bits)
Sama_2676 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Shewanella amazonensis SB2B
28% identity, 84% coverage of query (72.4 bits)
SSDH2_SCHPO / Q9UTM8 Putative succinate-semialdehyde dehydrogenase C139.05 [NADP(+)]; SSDH; EC 1.2.1.16 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 82% coverage of query (71.6 bits)
FUS7_GIBF5 / S0ENH1 Putative aldehyde dehydrogenase FUS7; Fusarin biosynthesis protein 7; EC 1.2.1.3 from Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi) (see 2 papers)
25% identity, 82% coverage of query (71.6 bits)
nmpF / A0A222FYW4 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Alicycliphilus sp. (see paper)
27% identity, 86% coverage of query (70.9 bits)
SSDH_RAT / P51650 Succinate-semialdehyde dehydrogenase, mitochondrial; SSADH; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase; EC 1.2.1.24 from Rattus norvegicus (Rat) (see paper)
P51650 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Rattus norvegicus (see paper)
26% identity, 74% coverage of query (68.9 bits)
Q9L4P8 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Staphylococcus aureus (see paper)
25% identity, 86% coverage of query (68.6 bits)
4neaA / A0A0H2X0S3 1.90 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus in complex with NAD+ and bme-free cys289 (see paper)
25% identity, 86% coverage of query (68.2 bits)
SLAD_PSEPU / P0DOV9 3-sulfolactaldehyde dehydrogenase; SLA dehydrogenase; EC 1.2.1.97 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
26% identity, 83% coverage of query (67.4 bits)
2d4eC / Q5SJP9 Crystal structure of the hpcc from thermus thermophilus hb8
26% identity, 82% coverage of query (64.7 bits)
VDH_CORGL / Q8NMB0 Vanillin dehydrogenase; Aromatic aldehyde dehydrogenase; EC 1.2.1.67; EC 1.2.1.64; EC 1.2.1.96 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
Q8NMB0 vanillin dehydrogenase (EC 1.2.1.67) from Corynebacterium glutamicum (see paper)
25% identity, 91% coverage of query (63.9 bits)
5ek6A Thermostable aldehyde dehydrogenase from pyrobaculum sp. 1860 complexed with NADP and isobutyraldehyde
25% identity, 77% coverage of query (62.0 bits)
4h73A Thermostable aldehyde dehydrogenase from pyrobaculum sp. Complexed with NADP+
25% identity, 77% coverage of query (62.0 bits)
5ekcE / G7VCG0 Thermostable aldehyde dehydrogenase from pyrobaculum sp.1860 complexed with NADP+
25% identity, 77% coverage of query (61.6 bits)
AL1L1_RAT / P28037 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; FBP-CI; EC 1.5.1.6 from Rattus norvegicus (Rat) (see 7 papers)
P28037 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Rattus norvegicus (see 3 papers)
23% identity, 92% coverage of query (60.5 bits)
4go2A Crystal structure of thE C-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with thio-NADP
23% identity, 92% coverage of query (60.1 bits)
2o2rA Crystal structure of thE C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
23% identity, 92% coverage of query (60.1 bits)
7rluA / P28037 Structure of aldh1l1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP (see paper)
23% identity, 92% coverage of query (59.3 bits)
4f3xA / Q92ND9 Crystal structure of putative aldehyde dehydrogenase from sinorhizobium meliloti 1021 complexed with NAD
27% identity, 91% coverage of query (55.5 bits)
6fkuA / Q72KD3 Structure and function of aldehyde dehydrogenase from thermus thermophilus: an enzyme with an evolutionarily-distinct c-terminal arm (recombinant protein with shortened c-terminal, in complex with NADP) (see paper)
25% identity, 89% coverage of query (53.9 bits)
ALDH1A3 / P47895 retinal dehydrogenase 3 (EC 1.2.1.36) from Homo sapiens (see 3 papers)
AL1A3_HUMAN / P47895 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; ALDH1A3; EC 1.2.1.36 from Homo sapiens (Human) (see 9 papers)
P47895 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Homo sapiens (see 6 papers)
24% identity, 88% coverage of query (53.5 bits)
ALDH1L1 / O75891 10-formyltetrahydrofolate dehydrogenase 1 (EC 3.5.1.10; EC 1.5.1.6) from Homo sapiens (see 7 papers)
AL1L1_HUMAN / O75891 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; EC 1.5.1.6 from Homo sapiens (Human) (see 3 papers)
O75891 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Homo sapiens (see paper)
24% identity, 75% coverage of query (53.1 bits)
7qk9A Crystal structure of the aldh1a3-atp complex
24% identity, 88% coverage of query (53.1 bits)
7a6qB Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound
24% identity, 88% coverage of query (53.1 bits)
7a6qA / P47895 Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound (see paper)
24% identity, 88% coverage of query (53.1 bits)
5fhzA Human aldehyde dehydrogenase 1a3 complexed with NAD(+) and retinoic acid
24% identity, 88% coverage of query (53.1 bits)
7yjjC Human cytosolic 10-formyltetrahydrofolate dehydrogenase and gossypol complex
24% identity, 75% coverage of query (53.1 bits)
6s6wA Crystal structure of human aldh1a3 in complex with 2,6- diphenylimidazo[1,2-a]pyridine (compound ga11) and NAD+
24% identity, 88% coverage of query (52.8 bits)
6tgwA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with a selective inhibitor
24% identity, 88% coverage of query (52.8 bits)
6tryA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with mf13 inhibitor compound
24% identity, 88% coverage of query (52.4 bits)
6te5B Crystal structure of human aldehyde dehydrogenase 1a3 in complex with lq43 inhibitor compound
24% identity, 88% coverage of query (52.4 bits)
6j76A Structure of 3,6-anhydro-l-galactose dehydrogenase in complex with nap (see paper)
23% identity, 85% coverage of query (49.3 bits)
7uyyA / Q9HWJ2 The crystal structure of the pseudomonas aeruginosa aldehyde dehydrogenase encoded by the pa4189 gene in complex with nadh (see paper)
25% identity, 87% coverage of query (47.0 bits)
4jz6A / Q1XGL7 Crystal structure of a salicylaldehyde dehydrogenase from pseudomonas putida g7 complexed with salicylaldehyde (see paper)
23% identity, 73% coverage of query (45.8 bits)
Or start over
Lawrence Berkeley National Laboratory