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Searching for up to 100 curated homologs for CCNA_03048 FitnessBrowser__Caulo:CCNA_03048 (524 a.a.)

Found high-coverage hits (≥70%) to 27 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

para-aminobenzoate synthase component I / b1812 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
pabB / P05041 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli (strain K12) (see 17 papers)
PABB_ECOLI / P05041 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Escherichia coli (strain K12) (see 8 papers)
pabB / RF|NP_416326.1 para-aminobenzoate synthase, component 1; EC 2.6.1.85 from Escherichia coli K12 (see 8 papers)
    38% identity, 84% coverage of query (250 bits)

1k0eA / P05041 The crystal structure of aminodeoxychorismate synthase from formate grown crystals (see paper)
    37% identity, 84% coverage of query (234 bits)

7pi1DDD / P28820 7pi1DDD
    34% identity, 75% coverage of query (221 bits)

B2FR92 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) (EC 2.6.1.123) from Stenotrophomonas maltophilia (see paper)
    39% identity, 78% coverage of query (221 bits)

pabB / P28820 4-amino-4-deoxychorismate synthase (para-aminobenzoate synthase) (EC 2.6.1.123) from Bacillus subtilis (strain 168) (see paper)
PABB_BACSU / P28820 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Bacillus subtilis (strain 168) (see 2 papers)
P28820 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) (EC 2.6.1.123); aminodeoxychorismate synthase (EC 2.6.1.85) from Bacillus subtilis (see 2 papers)
pabB / GB|BAA05309.1 para-aminobenzoate synthase, component 1; EC 2.6.1.85 from Bacillus subtilis (see paper)
    34% identity, 75% coverage of query (218 bits)

8hx8A / F2RB79 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae co-crystallized with chorismate (see paper)
    40% identity, 71% coverage of query (214 bits)

papA / BAD21140.1 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae (see paper)
    39% identity, 71% coverage of query (212 bits)

8hx9A / F2RB79 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae with chorismate (see paper)
    40% identity, 71% coverage of query (212 bits)

cmlB / F2RB79 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see 2 papers)
ADCS_STRVP / F2RB79 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoate synthase; EC 2.6.1.85 from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
    39% identity, 71% coverage of query (211 bits)

1k0gA The crystal structure of aminodeoxychorismate synthase from phosphate grown crystals
    34% identity, 84% coverage of query (201 bits)

trpE / Q08653 anthranilate synthase component I (EC 4.1.3.27) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    33% identity, 70% coverage of query (200 bits)

1k0gB / P05041 The crystal structure of aminodeoxychorismate synthase from phosphate grown crystals (see paper)
    34% identity, 83% coverage of query (196 bits)

TRPE_PSEPU / P20579 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    34% identity, 75% coverage of query (185 bits)

trpE / BAC65122.2 anthranilate synthase component I from Burkholderia multivorans (see paper)
    33% identity, 76% coverage of query (184 bits)

5cwaA / P9WFX2 Structure of anthranilate synthase component i (trpe) from mycobacterium tuberculosis with inhibitor bound (see paper)
    34% identity, 72% coverage of query (181 bits)

Q9YGB3 anthranilate synthase (EC 4.1.3.27) from Thermococcus kodakarensis (see paper)
    33% identity, 77% coverage of query (181 bits)

trpE / P20580 anthranilate synthase α subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TRPE_PSEAE / P20580 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P20580 anthranilate synthase (subunit 1/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
    32% identity, 82% coverage of query (179 bits)

O94582 Probable anthranilate synthase component 1; Anthranilate synthase component I; EC 4.1.3.27 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    34% identity, 74% coverage of query (179 bits)

trpE / AAA25223.1 anthranilate synthase alpha subunit from Lactococcus lactis (see paper)
    31% identity, 75% coverage of query (178 bits)

ASA1_ORYSJ / Q94GF1 Anthranilate synthase alpha subunit 1, chloroplastic; OsASA1; EC 4.1.3.27 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
    33% identity, 70% coverage of query (172 bits)

A0QX93 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    33% identity, 76% coverage of query (167 bits)

trpE / AAD09116.1 anthranilate synthase component I from Rhodobacter sphaeroides (see paper)
    32% identity, 83% coverage of query (160 bits)

TRPE_SALTY / P00898 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
    33% identity, 73% coverage of query (143 bits)

1i1qA / P00898 Structure of the cooperative allosteric anthranilate synthase from salmonella typhimurium (see paper)
    33% identity, 73% coverage of query (143 bits)

TryD / b1264 anthranilate synthase subunit TrpE (EC 4.1.3.27) from Escherichia coli K-12 substr. MG1655 (see paper)
trpE / P00895 anthranilate synthase subunit TrpE (EC 4.1.3.27) from Escherichia coli (strain K12) (see 10 papers)
TRPE_ECOLI / P00895 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Escherichia coli (strain K12) (see 3 papers)
    32% identity, 73% coverage of query (139 bits)

Build an alignment

Build an alignment for CCNA_03048 and 25 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

ADCS_SCHPO / O94277 Putative aminodeoxychorismate synthase; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    28% identity, 77% coverage of query (139 bits)

ADCS_YEAST / P37254 Aminodeoxychorismate synthase; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    28% identity, 74% coverage of query (124 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory