Sites on a Tree

 

Searching for up to 100 curated homologs for CCNA_03752 FitnessBrowser__Caulo:CCNA_03752 (298 a.a.)

Found high-coverage hits (≥70%) to 61 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

2ux8G / Q5FYV5 Crystal structure of sphingomonas elodea atcc 31461 glucose-1- phosphate uridylyltransferase in complex with glucose-1-phosphate. (see paper)
    56% identity, 97% coverage of query (343 bits)

A0A0W1QGK2 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Sphingomonas sp. WG (see paper)
    56% identity, 98% coverage of query (343 bits)

CAA80348.1 ExoN from Sinorhizobium meliloti (see paper)
    59% identity, 93% coverage of query (338 bits)

gtaB / Q05852 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.64) from Bacillus subtilis (strain 168) (see 3 papers)
GTAB_BACSU / Q05852 UTP--glucose-1-phosphate uridylyltransferase; Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; UGPase; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Bacillus subtilis (strain 168) (see 6 papers)
    52% identity, 93% coverage of query (293 bits)

gtaB / Q2G1T6 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.64) from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
GTAB_STAA8 / Q2G1T6 UTP--glucose-1-phosphate uridylyltransferase; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    52% identity, 92% coverage of query (286 bits)

A0A0H2X8N4 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Xanthomonas campestris pv. campestris (see paper)
    48% identity, 97% coverage of query (269 bits)

5i1fA / A4JT02 Crystal structure of utp-glucose-1-phosphate uridylyltransferase from burkholderia vietnamiensis in complex with uridine-5'-diphosphate- glucose
    47% identity, 94% coverage of query (265 bits)

2ux8A / Q5FYV5 Crystal structure of sphingomonas elodea atcc 31461 glucose-1- phosphate uridylyltransferase in complex with glucose-1-phosphate. (see paper)
    48% identity, 97% coverage of query (265 bits)

Q8PK83 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Xanthomonas citri (see paper)
    48% identity, 98% coverage of query (263 bits)

AAV49509.1 UDP-glucose pyrophosphorylase from Acidithiobacillus ferrooxidans (see paper)
    47% identity, 94% coverage of query (262 bits)

5ve7A / B1YNX3 Crystal structure of utp-glucose-1-phosphate uridylyltransferase from burkholderia ambifaria in complex with utp
    48% identity, 93% coverage of query (261 bits)

epsT / BAC55148.1 UDP-glucose pyrophosphorylase EpsT from Methylobacillus sp. 12S (see paper)
    45% identity, 97% coverage of query (256 bits)

YNGB_BACSU / O31822 UTP--glucose-1-phosphate uridylyltransferase YngB; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; UGPase; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Bacillus subtilis (strain 168) (see paper)
    45% identity, 97% coverage of query (253 bits)

6k8dA / X2KZJ9 Udp-glucose pyrophosphorylase with upg from acinetobacter baumanii
    46% identity, 92% coverage of query (244 bits)

6knlA Uridine and triphosphate-bound ugpase from acinetobacter baumannii
    46% identity, 92% coverage of query (244 bits)

GalU / b1236 UTP—glucose-1-phosphate uridylyltransferase (EC 2.7.7.64; EC 2.7.7.9) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
galU / P0AEP3 UTP—glucose-1-phosphate uridylyltransferase (EC 2.7.7.64) from Escherichia coli (strain K12) (see 30 papers)
GALU_ECOLI / P0AEP3 UTP--glucose-1-phosphate uridylyltransferase; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-Glc PPase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Escherichia coli (strain K12) (see 2 papers)
GALU_SHIFL / P0AEP6 UTP--glucose-1-phosphate uridylyltransferase; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Shigella flexneri (see paper)
galU UTP--glucose-1-phosphate uridylyltransferase; EC 2.7.7.9 from Escherichia coli K12 (see 7 papers)
galU / AAA20118.1 glucosephosphate uridylyltransferase from Escherichia coli (see 3 papers)
galU / AAD15244.1 UDP-glucose pyrophosphorylase from Shigella flexneri (see paper)
    44% identity, 95% coverage of query (230 bits)

Q8GQP8 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Streptococcus equi (see paper)
hasC / AAN65250.1 UDP-glucose pyrophosphorylase from Streptococcus equi subsp. zooepidemicus (see paper)
    45% identity, 92% coverage of query (229 bits)

6ikzB Udp-glucose pyrophosphorylase from acinetobacter baumanii
    44% identity, 92% coverage of query (228 bits)

Q54800 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Streptococcus pneumoniae (see paper)
cap3C / CAA87405.1 glucosephosphate uridylyltransferase from Streptococcus pneumoniae (see 2 papers)
    42% identity, 96% coverage of query (225 bits)

A0A0H2ZMV4 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Streptococcus pneumoniae (see paper)
    46% identity, 91% coverage of query (224 bits)

galU / CAA06172.1 UTP-glucose-1-phosphate uridylyltransferase from Streptococcus pneumoniae (see paper)
    45% identity, 91% coverage of query (222 bits)

8f73E / Q9I291 Crystal structure of pseudomonas aeruginosa udp-glucose phosphorylase in complex with udp-glucose
    43% identity, 89% coverage of query (207 bits)

O25363 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Helicobacter pylori (see paper)
    41% identity, 91% coverage of query (205 bits)

YefG / b2042 UTP:glucose-1-phosphate uridylyltransferase, low activity from Escherichia coli K-12 substr. MG1655 (see 7 papers)
    39% identity, 95% coverage of query (195 bits)

3jukA / O25363 The crystal structure of udp-glucose pyrophosphorylase complexed with udp-glucose (see paper)
    40% identity, 91% coverage of query (191 bits)

3jukD The crystal structure of udp-glucose pyrophosphorylase complexed with udp-glucose
    40% identity, 91% coverage of query (191 bits)

galF / AAC63611.1 GalF from Escherichia coli (see 6 papers)
    38% identity, 95% coverage of query (188 bits)

8b6dA / A0A2W4LV58 Crystal structure of udp-glucose pyrophosphorylase from thermocrispum agreste dsm 44070 in complex with udp
    43% identity, 93% coverage of query (181 bits)

8b68A Crystal structure of udp-glucose pyrophosphorylase from thermocrispum agreste dsm 44070 in complex with udp-glucose
    41% identity, 93% coverage of query (168 bits)

O05576 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Mycobacterium tuberculosis (see paper)
    40% identity, 93% coverage of query (162 bits)

2pa4B Crystal structure of udp-glucose pyrophosphorylase from corynebacteria glutamicum in complex with magnesium and udp-glucose (see paper)
    37% identity, 96% coverage of query (154 bits)

Q8YS18 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Nostoc sp. (see paper)
    31% identity, 87% coverage of query (117 bits)

agl11 / D4GU70 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL11_HALVD / D4GU70 Low-salt glycan biosynthesis nucleotidyltransferase Agl11; EC 2.7.7.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    30% identity, 88% coverage of query (105 bits)

Build an alignment

Build an alignment for CCNA_03752 and 33 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

mtmD / Q194R4 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces argillaceus (see paper)
mtmD / CAK50774.1 dTDP-glucose synthase from Streptomyces argillaceus (see 21 papers)
    27% identity, 88% coverage of query (76.6 bits)

dnmL / C6K8M0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces peucetius subsp. caesius ATCC 27952 (see 2 papers)
C6K8M0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces peucetius (see paper)
    28% identity, 88% coverage of query (75.5 bits)

GMPPB_HUMAN / Q9Y5P6 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Homo sapiens (Human) (see 4 papers)
Q9Y5P6 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Homo sapiens (see paper)
7d72K / Q9Y5P6 Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
    30% identity, 76% coverage of query (70.1 bits)

GMPPB_PIG / P0C5I2 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase 37-kDa subunit; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Sus scrofa (Pig) (see 2 papers)
    30% identity, 76% coverage of query (70.1 bits)

7d73E Cryo-em structure of gmppa/gmppb complex bound to gtp (state i)
    30% identity, 76% coverage of query (70.1 bits)

7d72E Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose
    30% identity, 76% coverage of query (70.1 bits)

oleS / Q9RR29 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces antibioticus (see paper)
OLES_STRAT / Q9RR29 Glucose-1-phosphate thymidylyltransferase; EC 2.7.7.24 from Streptomyces antibioticus (see paper)
    27% identity, 88% coverage of query (68.6 bits)

Q400H3 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Thermus caldophilus (see paper)
    27% identity, 88% coverage of query (68.2 bits)

GMPPB_DANRE / Q6DBU5 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
Q6DBU5 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Danio rerio (see paper)
    30% identity, 76% coverage of query (67.0 bits)

Q2HR55 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces sp. (see paper)
    25% identity, 88% coverage of query (67.0 bits)

CUGP_SYNY3 / P74285 UTP--glucose-1-phosphate uridylyltransferase; Cyanobacterial UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase; UDP-Glc PPase; EC 2.7.7.9 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
P74285 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Synechocystis sp. (see paper)
    26% identity, 77% coverage of query (65.9 bits)

rhsA / AAC44072.1 glucose-1-phosphate thymidylyltransferase from Sphingomonas sp. S88 (see paper)
    24% identity, 81% coverage of query (65.9 bits)

GLMU_METJA / Q58501 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
    26% identity, 89% coverage of query (65.9 bits)

Q4U3E8 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Aspergillus fumigatus (see paper)
    28% identity, 85% coverage of query (65.1 bits)

ST0452 / Q975F9 multifunctional glucose-1-phosphate thymidylyltransferase/hexosamine-1-phosphate N-acetyltransferase/UDP-N-acetylhexosamine diphosphorylase (EC 2.7.7.24; EC 2.7.7.23; EC 2.7.7.83; EC 2.3.1.157; EC 2.3.1.276) from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (see 2 papers)
S1PNA_SULTO / Q975F9 Bifunctional sugar-1-phosphate nucleotidylyltransferase/acetyltransferase; EC 2.7.7.24; EC 2.7.7.9; EC 2.7.7.83; EC 2.7.7.23; EC 2.3.1.276; EC 2.3.1.157 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see 5 papers)
Q975F9 glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157); galactosamine-1-phosphate N-acetyltransferase (EC 2.3.1.276); UDP-N-acetylglucosamine diphosphorylase (EC 2.7.7.23); glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24); aldose-1-phosphate nucleotidyltransferase (EC 2.7.7.37); UDP-N-acetylgalactosamine diphosphorylase (EC 2.7.7.83); UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Sulfurisphaera tokodaii (see 7 papers)
2ggqA / Q975F9 Complex of hypothetical glucose-1-phosphate thymidylyltransferase from sulfolobus tokodaii
    25% identity, 88% coverage of query (64.7 bits)

7x8kB / O22287 Arabidopsis gdp-d-mannose pyrophosphorylase (vtc1) structure (product- bound) (see paper)
    26% identity, 85% coverage of query (64.3 bits)

CYT1 / O22287 GDP-D-mannose pyrophosphorylase (EC 2.7.7.13) from Arabidopsis thaliana (see paper)
GMPP1_ARATH / O22287 Mannose-1-phosphate guanylyltransferase 1; GDP-mannose pyrophosphorylase 1; Protein CYTOKINESIS DEFECTIVE 1; Protein EMBRYO DEFECTIVE 101; Protein HYPERSENSITIVE TO AMMONIUM ION 1; Protein SENSITIVE TO OZONE 1; Protein VITAMIN C DEFECTIVE 1; EC 2.7.7.13 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
O22287 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Arabidopsis thaliana (see 2 papers)
    26% identity, 85% coverage of query (64.3 bits)

A0EJL9 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13); mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) from Malpighia glabra (see 2 papers)
    26% identity, 85% coverage of query (63.9 bits)

7x8kA Arabidopsis gdp-d-mannose pyrophosphorylase (vtc1) structure (product- bound)
    26% identity, 85% coverage of query (63.9 bits)

Q54K39 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Solanum lycopersicum (see paper)
    27% identity, 85% coverage of query (63.5 bits)

MPG1_HYPJE / O74624 Mannose-1-phosphate guanyltransferase; GDP-mannose pyrophosphorylase; GTP-mannose-1-phosphate guanylyltransferase; EC 2.7.7.13 from Hypocrea jecorina (Trichoderma reesei) (see paper)
O74624 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Trichoderma reesei (see 2 papers)
    26% identity, 85% coverage of query (63.2 bits)

ptmE / Q0P8S9 glucosamine-1-phosphate guanylyltransferase from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
    25% identity, 87% coverage of query (62.4 bits)

6n0uA / B2JFC5 Crystal structure of a glucose-1-phosphate thymidylyltransferase from burkholderia phymatum bound to 2'-deoxy-thymidine-b-l-rhamnose
    25% identity, 81% coverage of query (60.5 bits)

7whsA / E9BG32 Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gtp (see paper)
    25% identity, 85% coverage of query (58.5 bits)

5ifyA / A4JC15 Crystal structure of glucose-1-phosphate thymidylyltransferase from burkholderia vietnamiensis in complex with 2 -deoxyuridine-5'- monophosphate and 2'-deoxy-thymidine-b-l-rhamnose
    24% identity, 79% coverage of query (57.4 bits)

7whtA Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gdp-mannose
    25% identity, 76% coverage of query (51.6 bits)

YifG / b3789 dTDP-glucose pyrophosphorylase 2 (EC 2.7.7.24) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
rffH / P61887 glucose-1-phosphate thymidylyltransferase 2 (EC 2.7.7.24) from Escherichia coli (strain K12) (see 4 papers)
RMLA2_ECOLI / P61887 Glucose-1-phosphate thymidylyltransferase 2; G1P-TT 2; dTDP-glucose pyrophosphorylase 2; dTDP-glucose synthase 2; EC 2.7.7.24 from Escherichia coli (strain K12) (see 2 papers)
rmlA2 / RF|NP_418236 dTDP-glucose pyrophosphorylase 2; EC 2.7.7.24 from Escherichia coli K12 (see 6 papers)
    24% identity, 70% coverage of query (48.9 bits)

1mc3A / P61887 Crystal structure of rffh (see paper)
    24% identity, 70% coverage of query (48.5 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory