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Searching for up to 100 curated homologs for Dsui_0019 FitnessBrowser__PS:Dsui_0019 (532 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BPHYT_RS12305 Malate synthase (EC 2.3.3.9) from Burkholderia phytofirmans PsJN
    70% identity, 100% coverage of query (792 bits)

3cuxA / A0A6L8PPD0 Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design (see paper)
    53% identity, 98% coverage of query (556 bits)

Q5YLB8 malate synthase (EC 2.3.3.9) from Paracoccidioides brasiliensis (see 2 papers)
    52% identity, 98% coverage of query (549 bits)

CH_124037 putative malate synthase [Candida tropicalis] from Magnaporthe grisea 70-15 (see paper)
    52% identity, 98% coverage of query (543 bits)

acuE malate synthase; EC 2.3.3.9 from Emericella nidulans (see 5 papers)
    52% identity, 98% coverage of query (530 bits)

MASY_DICDI / Q8T2K9 Malate synthase; EC 2.3.3.9 from Dictyostelium discoideum (Social amoeba) (see paper)
    50% identity, 98% coverage of query (525 bits)

Q9ZH77 malate synthase (EC 2.3.3.9) from Streptomyces clavuligerus (see paper)
    50% identity, 98% coverage of query (514 bits)

MLS1 malate synthase; EC 2.3.3.9 from Candida albicans (see paper)
    50% identity, 98% coverage of query (511 bits)

MLS1 / P30952 malate synthase (EC 2.3.3.7; EC 2.3.3.9) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
MLS1_YEAST / P30952 Malate synthase 1; EC 2.3.3.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    49% identity, 96% coverage of query (501 bits)

DAL7 / P21826 malate synthase 2 (EC 2.3.3.7; EC 2.3.3.9) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
MLS2_YEAST / P21826 Malate synthase 2; Degradation of allantoin protein 7; EC 2.3.3.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
    48% identity, 97% coverage of query (495 bits)

GCP_CAEEL / Q10663 Bifunctional glyoxylate cycle protein; Gex-3-interacting protein 7; EC 4.1.3.1; EC 2.3.3.9 from Caenorhabditis elegans (see 2 papers)
    48% identity, 98% coverage of query (492 bits)

Mas / b4014 malate synthase A (EC 2.3.3.9) from Escherichia coli K-12 substr. MG1655 (see 14 papers)
aceB / P08997 malate synthase A (EC 2.3.3.9) from Escherichia coli (strain K12) (see 15 papers)
    46% identity, 98% coverage of query (487 bits)

3cuzA / P08997 Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design (see paper)
    46% identity, 98% coverage of query (487 bits)

3cv1A Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design
    46% identity, 98% coverage of query (487 bits)

3cv2A Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design
    46% identity, 98% coverage of query (486 bits)

SO1483 Malate synthase (EC 2.3.3.9) from Shewanella oneidensis MR-1
    47% identity, 97% coverage of query (484 bits)

MLS / Q9LZC3 malate synthase (EC 2.3.3.9) from Arabidopsis thaliana (see paper)
MASY_ARATH / Q9LZC3 Malate synthase; EC 2.3.3.9 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    47% identity, 98% coverage of query (480 bits)

MASY_ORYSJ / Q7XUG1 Malate synthase; EC 2.3.3.9 from Oryza sativa subsp. japonica (Rice) (see paper)
    47% identity, 99% coverage of query (466 bits)

CAA40262.1 malate synthase from Cucurbita hybrid cultivar (see paper)
    45% identity, 99% coverage of query (460 bits)

Build an alignment

Build an alignment for Dsui_0019 and 19 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

3s9iA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-4-dioxo-4-phenylbutanoic acid inhibitor
    22% identity, 72% coverage of query (46.6 bits)

3sazA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4-(3-bromophenyl)-2,4-dioxobutanoic acid inhibitor
    21% identity, 74% coverage of query (44.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory