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Searching for up to 100 curated homologs for Dsui_0219 FitnessBrowser__PS:Dsui_0219 (491 a.a.)

Found high-coverage hits (≥70%) to 46 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

trpE / BAC65122.2 anthranilate synthase component I from Burkholderia multivorans (see paper)
    61% identity, 100% coverage of query (603 bits)

TRPE_PSEPU / P20579 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    61% identity, 98% coverage of query (592 bits)

trpE / P20580 anthranilate synthase α subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TRPE_PSEAE / P20580 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P20580 anthranilate synthase (subunit 1/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
    60% identity, 99% coverage of query (573 bits)

trpE / AAD09116.1 anthranilate synthase component I from Rhodobacter sphaeroides (see paper)
    51% identity, 96% coverage of query (382 bits)

trpE / Q08653 anthranilate synthase component I (EC 4.1.3.27) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    44% identity, 95% coverage of query (370 bits)

7pi1DDD / P28820 7pi1DDD
    44% identity, 93% coverage of query (363 bits)

ASA1_ORYSJ / Q94GF1 Anthranilate synthase alpha subunit 1, chloroplastic; OsASA1; EC 4.1.3.27 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
    41% identity, 98% coverage of query (363 bits)

pabB / P28820 4-amino-4-deoxychorismate synthase (para-aminobenzoate synthase) (EC 2.6.1.123) from Bacillus subtilis (strain 168) (see paper)
PABB_BACSU / P28820 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Bacillus subtilis (strain 168) (see 2 papers)
P28820 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) (EC 2.6.1.123); aminodeoxychorismate synthase (EC 2.6.1.85) from Bacillus subtilis (see 2 papers)
pabB / GB|BAA05309.1 para-aminobenzoate synthase, component 1; EC 2.6.1.85 from Bacillus subtilis (see paper)
    44% identity, 94% coverage of query (358 bits)

TRPE_ARATH / P32068 Anthranilate synthase alpha subunit 1, chloroplastic; Anthranilate synthase component 1-1; Anthranilate synthase component I-1; Protein A-METHYL TRYPTOPHAN RESISTANT 1; Protein JASMONATE-INDUCED DEFECTIVE LATERAL ROOT 1; Protein TRYPTOPHAN BIOSYNTHESIS 5; Protein WEAK ETHYLENE INSENSITIVE 2; EC 4.1.3.27 from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
    40% identity, 99% coverage of query (353 bits)

A0QX93 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    45% identity, 96% coverage of query (349 bits)

trpE / AAA25223.1 anthranilate synthase alpha subunit from Lactococcus lactis (see paper)
    44% identity, 93% coverage of query (348 bits)

O94582 Probable anthranilate synthase component 1; Anthranilate synthase component I; EC 4.1.3.27 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    42% identity, 96% coverage of query (346 bits)

5cwaA / P9WFX2 Structure of anthranilate synthase component i (trpe) from mycobacterium tuberculosis with inhibitor bound (see paper)
    44% identity, 96% coverage of query (345 bits)

P9WFX2 anthranilate synthase (EC 4.1.3.27) from Mycobacterium tuberculosis (see paper)
P9WFX3 anthranilate synthase (EC 4.1.3.27) from Mycobacterium tuberculosis (see paper)
    44% identity, 96% coverage of query (343 bits)

AANTSYNB / Q41156 anthranilate synthase α subunit (EC 4.1.3.27) from Ruta graveolens (see paper)
    41% identity, 96% coverage of query (340 bits)

ASA2_ORYSJ / Q9XJ29 Anthranilate synthase alpha subunit 2, chloroplastic; OsASA2; EC 4.1.3.27 from Oryza sativa subsp. japonica (Rice) (see 3 papers)
    40% identity, 96% coverage of query (338 bits)

Q9AW95 anthranilate synthase (EC 4.1.3.27) from Catharanthus roseus (see paper)
    41% identity, 97% coverage of query (337 bits)

7bvdA / A0QX93 Anthranilate synthase component i (trpe)[mycolicibacterium smegmatis]
    44% identity, 96% coverage of query (331 bits)

TRPE_YEAST / P00899 Anthranilate synthase component 1; Anthranilate synthase component I; EC 4.1.3.27 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    40% identity, 92% coverage of query (321 bits)

Q5XLF3 anthranilate synthase (EC 4.1.3.27) from Camptotheca acuminata (see paper)
    39% identity, 99% coverage of query (318 bits)

Q5XLF2 anthranilate synthase (EC 4.1.3.27) from Camptotheca acuminata (see paper)
    38% identity, 99% coverage of query (310 bits)

Q9YGB3 anthranilate synthase (EC 4.1.3.27) from Thermococcus kodakarensis (see paper)
    41% identity, 91% coverage of query (282 bits)

trpE / Q06128 anthranilate synthase α subunit (EC 4.1.3.27) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
TRPE_SACS2 / Q06128 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q06128 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Saccharolobus solfataricus (see paper)
    40% identity, 88% coverage of query (268 bits)

TryD / b1264 anthranilate synthase subunit TrpE (EC 4.1.3.27) from Escherichia coli K-12 substr. MG1655 (see paper)
trpE / P00895 anthranilate synthase subunit TrpE (EC 4.1.3.27) from Escherichia coli (strain K12) (see 10 papers)
TRPE_ECOLI / P00895 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Escherichia coli (strain K12) (see 3 papers)
    41% identity, 76% coverage of query (246 bits)

TRPE_SALTY / P00898 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
    40% identity, 76% coverage of query (246 bits)

1i1qA / P00898 Structure of the cooperative allosteric anthranilate synthase from salmonella typhimurium (see paper)
    40% identity, 76% coverage of query (244 bits)

1i7qA / P00897 Anthranilate synthase from s. Marcescens (see paper)
    34% identity, 93% coverage of query (238 bits)

SGCD_STRGL / Q8GMH4 2-amino-4-deoxychorismate synthase; ADIC synthase; EC 2.6.1.86 from Streptomyces globisporus (see paper)
    39% identity, 71% coverage of query (237 bits)

B2FR92 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) (EC 2.6.1.123) from Stenotrophomonas maltophilia (see paper)
    37% identity, 89% coverage of query (237 bits)

para-aminobenzoate synthase component I / b1812 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
pabB / P05041 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli (strain K12) (see 17 papers)
PABB_ECOLI / P05041 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Escherichia coli (strain K12) (see 8 papers)
pabB / RF|NP_416326.1 para-aminobenzoate synthase, component 1; EC 2.6.1.85 from Escherichia coli K12 (see 8 papers)
    33% identity, 91% coverage of query (235 bits)

1i7sA Anthranilate synthase from serratia marcescens in complex with its end product inhibitor l-tryptophan
    38% identity, 75% coverage of query (234 bits)

TRPE_SERMA / P00897 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Serratia marcescens (see paper)
P00897 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Serratia marcescens (see paper)
    38% identity, 75% coverage of query (231 bits)

phnA / P09785 PhnA anthranilate synthase subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
PHNA_PSEAE / P09785 Anthranilate synthase component 1, pyocyanine specific; AS; ASI; Anthranilate synthase alpha subunit, pyocyanine specific; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P09785 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
    33% identity, 93% coverage of query (227 bits)

trpE anthranilate synthase component I; EC 4.1.3.27 from Leptospira biflexa serovar Patoc (see paper)
    35% identity, 89% coverage of query (226 bits)

1k0eA / P05041 The crystal structure of aminodeoxychorismate synthase from formate grown crystals (see paper)
    32% identity, 91% coverage of query (220 bits)

pabAB / P32483 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces griseus (see 5 papers)
ADCS_STRGR / P32483 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoic acid synthase; PABA synthase; EC 2.6.1.85 from Streptomyces griseus (see paper)
    32% identity, 91% coverage of query (215 bits)

ADCS / Q8LPN3 aminodeoxychorismate synthase (EC 2.6.1.85) from Arabidopsis thaliana (see 2 papers)
ADCS_ARATH / Q8LPN3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; Protein EMBRYO DEFFECTIVE 1997; EC 2.6.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    34% identity, 78% coverage of query (211 bits)

ADCS / Q6TAS3 aminodeoxychorismate synthase (EC 2.6.1.85) from Solanum lycopersicum (see 2 papers)
ADCS_SOLLC / Q6TAS3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
    36% identity, 76% coverage of query (207 bits)

ADCS_STRPR / P72539 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; EC 2.6.1.85 from Streptomyces pristinaespiralis (see paper)
    35% identity, 78% coverage of query (206 bits)

8hx8A / Q6L8Q5 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae co-crystallized with chorismate (see paper)
    35% identity, 78% coverage of query (203 bits)

8hx9A / Q6L8Q5 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae with chorismate (see paper)
    35% identity, 78% coverage of query (202 bits)

papA / BAD21140.1 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae (see paper)
    35% identity, 78% coverage of query (202 bits)

cmlB / F2RB79 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see 2 papers)
ADCS_STRVP / F2RB79 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoate synthase; EC 2.6.1.85 from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
    34% identity, 78% coverage of query (201 bits)

1k0gA The crystal structure of aminodeoxychorismate synthase from phosphate grown crystals
    31% identity, 91% coverage of query (199 bits)

1k0gB / P05041 The crystal structure of aminodeoxychorismate synthase from phosphate grown crystals (see paper)
    31% identity, 90% coverage of query (197 bits)

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Build an alignment for Dsui_0219 and 45 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

ADCS_YEAST / P37254 Aminodeoxychorismate synthase; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    28% identity, 74% coverage of query (144 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory