Searching for up to 100 curated homologs for Dsui_2067 FitnessBrowser__PS:Dsui_2067 (232 a.a.)

Found high-coverage hits (≥70%) to 6 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

MetI / b0198 L-methionine/D-methionine ABC transporter membrane subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
MetI / P31547 L-methionine/D-methionine ABC transporter membrane subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 2 papers)
METI_ECOLI / P31547 D-methionine transport system permease protein MetI from Escherichia coli (strain K12) (see 3 papers)
P31547 ABC-type methionine transporter (subunit 1/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P31547 MetI, D-methionine transport system permease protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 4 papers)
    45% identity, 90% coverage of query (135 bits)

METP_BACSU / O32168 Methionine import system permease protein MetP from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.24.2 / O32168 MetP (M) (aka YusB), component of The L- and D-methionine porter (also transports methionine sulfoxide from Bacillus subtilis subsp. subtilis str. 168 (see 2 papers)
    40% identity, 92% coverage of query (132 bits)

TC 3.A.1.24.5 / Q9HT69 D-methionine ABC transporter membrane protein, component of L-Histidine uptake porter, MetIQN from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    49% identity, 77% coverage of query (124 bits)

TC 3.A.1.24.4 / Q8NSN3 ABC-type transporter, permease components, component of L-Methionine uptake porter, MetQNI from Corynebacterium glutamicum
    39% identity, 91% coverage of query (115 bits)

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Build an alignment for Dsui_2067 and 4 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 3.A.1.3.25 / Q9CES5 Glutamine ABC transporter permease and substrate binding protein protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
    25% identity, 91% coverage of query (55.8 bits)

ARTQ_BACSU / P54536 Arginine transport system permease protein ArtQ from Bacillus subtilis (strain 168) (see paper)
    26% identity, 83% coverage of query (49.7 bits)

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