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Searching for up to 100 curated homologs for Dsui_3211 FitnessBrowser__PS:Dsui_3211 (448 a.a.)

Found high-coverage hits (≥70%) to 94 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q8XDW9 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Escherichia coli (see paper)
    69% identity, 99% coverage of query (640 bits)

GdhA / b1761 glutamate dehydrogenase (EC 1.4.1.4) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
gdhA / P00370 glutamate dehydrogenase (EC 1.4.1.4) from Escherichia coli (strain K12) (see 38 papers)
DHE4_ECOLI / P00370 NADP-specific glutamate dehydrogenase; NADP-GDH; EC 1.4.1.4 from Escherichia coli (strain K12) (see 2 papers)
P00370 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Escherichia coli (see 3 papers)
    68% identity, 99% coverage of query (639 bits)

DHE4_PRERU / P95544 NAD(P)-specific glutamate dehydrogenase; NAD(P)-GDH; NAD(P)H-dependent glutamate dehydrogenase; EC 1.4.1.3 from Prevotella ruminicola (Bacteroides ruminicola) (see paper)
    60% identity, 98% coverage of query (563 bits)

P28724 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Giardia intestinalis (see paper)
    57% identity, 99% coverage of query (541 bits)

A0A0U4QBJ6 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Corynebacterium glutamicum (see paper)
    59% identity, 100% coverage of query (517 bits)

P31026 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Corynebacterium glutamicum (see paper)
    59% identity, 100% coverage of query (517 bits)

5gudA Glutamate dehydrogenase from corynebacterium glutamicum (alpha- iminoglutarate/NADP+ complex)
    59% identity, 100% coverage of query (517 bits)

5ijzA Crystal structure of glutamate dehydrogenase(gdh) from corynebacterium glutamicum
    59% identity, 100% coverage of query (517 bits)

5gudE / A0A0U4QBJ6 Glutamate dehydrogenase from corynebacterium glutamicum (alpha- iminoglutarate/NADP+ complex) (see paper)
    59% identity, 100% coverage of query (516 bits)

A0A1V1FMC4 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Streptococcus equinus (see paper)
    59% identity, 98% coverage of query (516 bits)

Q8ILF7 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Plasmodium falciparum (see paper)
    53% identity, 100% coverage of query (515 bits)

DHE2_CLOSY / P24295 NAD-specific glutamate dehydrogenase; NAD-GDH; EC 1.4.1.2 from Clostridium symbiosum (Bacteroides symbiosus) (see 4 papers)
P24295 glutamate dehydrogenase (EC 1.4.1.2) from [Clostridium] symbiosum (see 4 papers)
gdh / CAA77805.1 Glutamate Dehydrogenase from [Clostridium] symbiosum (see paper)
    54% identity, 100% coverage of query (499 bits)

1bgvA / P24295 Glutamate dehydrogenase (see paper)
    54% identity, 99% coverage of query (498 bits)

A0R3E3 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Mycolicibacterium smegmatis (see paper)
    56% identity, 100% coverage of query (498 bits)

Q9TVN3 glutamate dehydrogenase (EC 1.4.1.2) from Entodinium caudatum (see paper)
    54% identity, 98% coverage of query (490 bits)

DHE4_PSYT1 / Q9S1F9 NADP-specific glutamate dehydrogenase; NADP-GDH; EC 1.4.1.4 from Psychrobacter sp. (strain TAD1) (see paper)
    53% identity, 99% coverage of query (488 bits)

Q8ILT0 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Plasmodium falciparum (see paper)
    52% identity, 100% coverage of query (481 bits)

gdh / P00369 glutamate dehydrogenase subunit (EC 1.4.1.4) from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see paper)
    57% identity, 96% coverage of query (451 bits)

P00369 NADP-specific glutamate dehydrogenase; NADP-GDH; NADP-dependent glutamate dehydrogenase; EC 1.4.1.4 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
    57% identity, 96% coverage of query (451 bits)

7ecrA / T2D1F5 Crystal structure of aspergillus terreus glutamate dehydrogenase (atgdh) complexed with succinate and adp-ribose (see paper)
    56% identity, 96% coverage of query (447 bits)

7ecsA Crystal structure of aspergillus terreus glutamate dehydrogenase (atgdh) complexed with malonate and NADPH
    56% identity, 96% coverage of query (447 bits)

B6V7E4 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Aspergillus niger (see paper)
    54% identity, 96% coverage of query (437 bits)

5xvvB / B6V7E4 Crystal structure of forward inhibited aspergillus niger glutamate dehydrogenase with both apo- and alpha ketoglutarate bound subunits (see paper)
    54% identity, 96% coverage of query (437 bits)

5xwcA Crystal structure of aspergillus niger glutamate dehydrogenase complexed with alpha-iminoglutarate, 2-amino-2-hydroxyglutarate and NADP
    54% identity, 96% coverage of query (437 bits)

5xw0A Crystal structure of aspergillus niger glutamate dehydrogenase complexed with isophthalate and NADPH
    54% identity, 96% coverage of query (437 bits)

5xvxA Crystal structure of aspergillus niger glutamate dehydrogenase complexed with alpha-ketoglutarate and NADPH
    54% identity, 96% coverage of query (437 bits)

P18819 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Aspergillus nidulans (see paper)
gdhA NADP-specific glutamate dehydrogenase (NADP-GDH); EC 1.4.1.4 from Emericella nidulans (see 3 papers)
    54% identity, 96% coverage of query (436 bits)

A0A1D8PMH8 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Candida albicans (see 2 papers)
    50% identity, 96% coverage of query (435 bits)

7f79C / A0A1D8PMH8 Crystal structure of glutamate dehydrogenase 3 from candida albicans in complex with alpha-ketoglutarate and NADPH (see paper)
    50% identity, 96% coverage of query (435 bits)

C6EVR5 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Phaffia rhodozyma (see paper)
    52% identity, 96% coverage of query (433 bits)

Q6C1A9 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Yarrowia lipolytica (see paper)
    53% identity, 96% coverage of query (431 bits)

DHE4_YEAST / P07262 NADP-specific glutamate dehydrogenase 1; NADP-GDH 1; NADP-dependent glutamate dehydrogenase 1; EC 1.4.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P07262 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Saccharomyces cerevisiae (see 3 papers)
    50% identity, 96% coverage of query (421 bits)

P39708 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Saccharomyces cerevisiae (see paper)
    49% identity, 96% coverage of query (412 bits)

P78804 NADP-specific glutamate dehydrogenase; NADP-GDH; NADP-dependent glutamate dehydrogenase; EC 1.4.1.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    52% identity, 97% coverage of query (405 bits)

DHE4_HALSI / Q5MBG2 NADP-specific glutamate dehydrogenase A1; EC 1.4.1.4 from Halobacterium salinarum (Halobacterium halobium) (see paper)
    33% identity, 95% coverage of query (210 bits)

4xgiA / Q2SZ78 Crystal structure of glutamate dehydrogenase from burkholderia thailandensis
    35% identity, 82% coverage of query (194 bits)

O04937 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Nicotiana plumbaginifolia (see paper)
    34% identity, 81% coverage of query (194 bits)

DHE2_BACSU / P39633 Catabolic NAD-specific glutamate dehydrogenase RocG; NAD-GDH; Glutamate dehydrogenase; GlutDH; Trigger enzyme RocG; EC 1.4.1.2 from Bacillus subtilis (strain 168) (see 7 papers)
    32% identity, 81% coverage of query (192 bits)

O74024 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermococcus profundus (see 2 papers)
8xd5A / O74024 Cryo-em structure of glutamate dehydrogenase from thermococcus profundus in complex with NADP and glu in the steady stage of reaction
    35% identity, 79% coverage of query (191 bits)

8xcsA Cryo-em structure of glutamate dehydrogenase from thermococcus profundus in complex with NADPH, akg and nh4 in the initial stage of reaction
    35% identity, 79% coverage of query (191 bits)

8xcoA Cryo-em structure of glutamate dehydrogenase from thermococcus profundus incorporating NADPH in the initial stage of reaction
    35% identity, 79% coverage of query (191 bits)

3aoeB / Q72IC1 Crystal structure of hetero-hexameric glutamate dehydrogenase from thermus thermophilus (leu bound form)
    36% identity, 81% coverage of query (189 bits)

3aogA Crystal structure of glutamate dehydrogenase (gdhb) from thermus thermophilus (glu bound form)
    36% identity, 81% coverage of query (189 bits)

Q9Y8I4 glutamate dehydrogenase (EC 1.4.1.2) from Pyrobaculum islandicum (see paper)
    32% identity, 79% coverage of query (187 bits)

1v9lA / Q9Y8I4 L-glutamate dehydrogenase from pyrobaculum islandicum complexed with NAD (see paper)
    32% identity, 79% coverage of query (187 bits)

Q0E5I0 glutamate dehydrogenase (EC 1.4.1.2) from Halobacillus halophilus (see paper)
    32% identity, 79% coverage of query (186 bits)

P80319 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Pyrococcus furiosus (see 6 papers)
    33% identity, 89% coverage of query (185 bits)

gdhA / GB|AAA64795.1 glutamate dehydrogenase (NAD(P)(+)); EC 1.4.1.3 from Pyrococcus endeavori (see paper)
    34% identity, 79% coverage of query (184 bits)

Q5QDM6 glutamate dehydrogenase (EC 1.4.1.2) from Lupinus luteus (see paper)
    33% identity, 80% coverage of query (184 bits)

P96110 trimer complex (EC 1.4.1.2) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 3 papers)
P96110 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermotoga maritima (see paper)
gdhA glutamate dehydrogenase; EC 1.4.1.3 from Thermotoga maritima (see 2 papers)
    36% identity, 78% coverage of query (183 bits)

GDH2 / Q38946 glutamate dehydrogenase β subunit (EC 1.4.1.2) from Arabidopsis thaliana (see 4 papers)
DHE2_ARATH / Q38946 Glutamate dehydrogenase 2; GDH 2; EC 1.4.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q38946 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Arabidopsis thaliana (see paper)
    32% identity, 90% coverage of query (182 bits)

8owmC / Q38946 Crystal structure of glutamate dehydrogenase 2 from arabidopsis thaliana binding ca, NAD and 2,2-dihydroxyglutarate (see paper)
    32% identity, 90% coverage of query (182 bits)

DHE3_ORYSJ / Q6H3Y7 Glutamate dehydrogenase 3, mitochondrial; OsGDH3; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 4 papers)
    31% identity, 90% coverage of query (182 bits)

Q977X9 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Thermococcus waiotapuensis (see paper)
    33% identity, 89% coverage of query (179 bits)

DHE4_PYRCJ / A3MWK6 NADP(+)-dependent glutamate dehydrogenase; NADP-GDH; EC 1.4.1.4 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MWK6 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Pyrobaculum calidifontis (see paper)
    33% identity, 78% coverage of query (179 bits)

Q9LEC8 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Nicotiana plumbaginifolia (see 2 papers)
    33% identity, 81% coverage of query (179 bits)

Q9S7A0 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Arabidopsis thaliana (see paper)
    31% identity, 90% coverage of query (177 bits)

DHE2_ORYSJ / Q33E23 Glutamate dehydrogenase 2, mitochondrial; OsGDH2; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 7 papers)
    31% identity, 90% coverage of query (176 bits)

DHE3_THELN / Q56304 Glutamate dehydrogenase; GDH; EC 1.4.1.3 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 2 papers)
Q56304 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3); glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Thermococcus litoralis (see 5 papers)
    33% identity, 79% coverage of query (176 bits)

6yehA / Q43314 Arabidopsis thaliana glutamate dehydrogenase isoform 1 in apo form (see paper)
    31% identity, 90% coverage of query (176 bits)

Q43314 glutamate dehydrogenase (EC 1.4.1.2); glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Arabidopsis thaliana (see 2 papers)
    31% identity, 90% coverage of query (176 bits)

DHE2_PYRCJ / A3MUY9 NAD(+)-dependent glutamate dehydrogenase; NAD-GDH; NAD-specific glutamate dehydrogenase; EC 1.4.1.2 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MUY9 glutamate dehydrogenase (EC 1.4.1.2) from Pyrobaculum calidifontis (see paper)
    33% identity, 78% coverage of query (176 bits)

6yeiA Arabidopsis thaliana glutamate dehydrogenase isoform 1 in complex with NAD
    31% identity, 90% coverage of query (176 bits)

6yeiF Arabidopsis thaliana glutamate dehydrogenase isoform 1 in complex with NAD
    31% identity, 90% coverage of query (176 bits)

DHE1_ORYSJ / Q852M0 Glutamate dehydrogenase 1, mitochondrial; OsGDH1; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Q852M0 glutamate dehydrogenase (EC 1.4.1.2) from Oryza sativa (see paper)
    33% identity, 78% coverage of query (174 bits)

Q9YC65 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Aeropyrum pernix (see paper)
    33% identity, 85% coverage of query (172 bits)

GUDB_BACSU / P50735 Cryptic catabolic NAD-specific glutamate dehydrogenase GudB; NAD-GDH; EC 1.4.1.2 from Bacillus subtilis (strain 168) (see 3 papers)
    32% identity, 76% coverage of query (172 bits)

GDH1 / P93541 glutamate dehydrogenase (EC 1.4.1.3) from Solanum lycopersicum (see paper)
P93541 glutamate dehydrogenase (EC 1.4.1.2) from Solanum lycopersicum (see paper)
    32% identity, 81% coverage of query (171 bits)

P80053 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Saccharolobus solfataricus (see paper)
    32% identity, 76% coverage of query (170 bits)

P80053 Glutamate dehydrogenase 2; GDH-2; EC 1.4.1.3 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
    32% identity, 76% coverage of query (170 bits)

gdhA / P28997 NAD-glutamate dehydrogenase subunit (EC 1.4.1.2) from Peptoniphilus asaccharolyticus (see paper)
DHE2_PEPAS / P28997 NAD-specific glutamate dehydrogenase; NAD-GDH; EC 1.4.1.2 from Peptoniphilus asaccharolyticus (Peptostreptococcus asaccharolyticus) (see 2 papers)
P28997 glutamate dehydrogenase (EC 1.4.1.2) from Peptoniphilus asaccharolyticus (see 2 papers)
    32% identity, 84% coverage of query (169 bits)

GLUD2 / P49448 Glutamate dehydrogenase 2, mitochondrial (EC 1.4.1.3) from Homo sapiens (see 3 papers)
DHE4_HUMAN / P49448 Glutamate dehydrogenase 2, mitochondrial; GDH 2; EC 1.4.1.3 from Homo sapiens (Human) (see paper)
P49448 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Homo sapiens (see 6 papers)
    32% identity, 79% coverage of query (167 bits)

O59650 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermococcus kodakarensis (see 2 papers)
gdhA glutamate dehydrogenase (NAD(P)(+)); EC 1.4.1.3 from Thermococcus kodakarensis (see paper)
    33% identity, 79% coverage of query (167 bits)

gdhB / P29051 GdhA (EC 1.4.1.4) from Halobacterium salinarum (see 3 papers)
DHE2_HALSI / P29051 NAD-specific glutamate dehydrogenase A; NAD-GDH A; EC 1.4.1.2 from Halobacterium salinarum (Halobacterium halobium) (see 2 papers)
P29051 glutamate dehydrogenase (EC 1.4.1.2) from Halobacterium salinarum (see 2 papers)
gdhA / GB|AAW19068.1 glutamate dehydrogenase; EC 1.4.1.2 from Halobacterium salinarum (see paper)
    30% identity, 89% coverage of query (166 bits)

1nqtA Crystal structure of bovine glutamate dehydrogenase-adp complex
    32% identity, 79% coverage of query (165 bits)

GLUD1 / P00367 Glutamate dehydrogenase 1, mitochondrial (EC 1.4.1.3) from Homo sapiens (see 3 papers)
DHE3_HUMAN / P00367 Glutamate dehydrogenase 1, mitochondrial; GDH 1; EC 1.4.1.3 from Homo sapiens (Human) (see 10 papers)
P00367 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Homo sapiens (see 8 papers)
    32% identity, 79% coverage of query (165 bits)

8ar7A Bovine glutamate dehydrogenase in ternary complex with the allosteric activators adp and leucine
    31% identity, 79% coverage of query (162 bits)

6dhmA Bovine glutamate dehydrogenase complexed with zinc
    31% identity, 79% coverage of query (162 bits)

6dhdA / P00366 Bovine glutamate dehydrogenase complexed with nadh, gtp, glutamate (see paper)
    31% identity, 79% coverage of query (162 bits)

3etgA Glutamate dehydrogenase complexed with gw5074
    31% identity, 79% coverage of query (162 bits)

3etdA Structure of glutamate dehydrogenase complexed with bithionol
    31% identity, 79% coverage of query (162 bits)

6dhlA Bovine glutamate dehydrogenase complexed with epicatechin-3-gallate (ecg)
    31% identity, 79% coverage of query (162 bits)

3eteA Crystal structure of bovine glutamate dehydrogenase complexed with hexachlorophene
    31% identity, 79% coverage of query (162 bits)

DHE3_BOVIN / P00366 Glutamate dehydrogenase 1, mitochondrial; GDH 1; EC 1.4.1.3 from Bos taurus (Bovine) (see 4 papers)
P00366 glutamate dehydrogenase (EC 1.4.1.2); glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Bos taurus (see 3 papers)
    30% identity, 82% coverage of query (160 bits)

1hwyA Bovine glutamate dehydrogenase complexed with NAD and 2-oxoglutarate
    31% identity, 79% coverage of query (159 bits)

3aoeF / Q72IC0 Crystal structure of hetero-hexameric glutamate dehydrogenase from thermus thermophilus (leu bound form)
    30% identity, 97% coverage of query (154 bits)

Build an alignment

Build an alignment for Dsui_3211 and 86 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

1c1dA L-phenylalanine dehydrogenase structure in ternary complex with nadh and l-phenylalanine
    28% identity, 72% coverage of query (63.2 bits)

1c1xA L-phenylalanine dehydrogenase structure in ternary complex with NAD+ and l-3-phenyllactate
    28% identity, 72% coverage of query (63.2 bits)

1bw9A / Q59771 Phenylalanine dehydrogenase structure in ternary complex with NAD+ and phenylpyruvate (see paper)
    28% identity, 72% coverage of query (63.2 bits)

DHPH_RHOSO / Q59771 Phenylalanine dehydrogenase; PheDH; EC 1.4.1.20 from Rhodococcus sp. (see 2 papers)
pdh / AAA21461.1 L-phenylalanine dehydrogenase precursor from Rhodococcus sp (see paper)
    28% identity, 72% coverage of query (60.8 bits)

1bxgA Phenylalanine dehydrogenase structure in ternary complex with NAD+ and beta-phenylpropionate
    28% identity, 72% coverage of query (60.8 bits)

DHLE_GEOSE / P13154 Leucine dehydrogenase; LeuDH; EC 1.4.1.9 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
P13154 leucine dehydrogenase (EC 1.4.1.9) from Geobacillus stearothermophilus (see paper)
    26% identity, 73% coverage of query (55.5 bits)

6achA Structure of NAD+-bound leucine dehydrogenase from geobacillus stearothermophilus by cryo-em (see paper)
    25% identity, 73% coverage of query (55.5 bits)

8hr6A Leucine dehydrogenase structure in ternary complex with NAD+ from bacillus thuringiensis (see paper)
    24% identity, 72% coverage of query (50.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory