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Searching for up to 100 curated homologs for Dsui_3224 FitnessBrowser__PS:Dsui_3224 (111 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q48G05 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Pseudomonas syringae (see paper)
    36% identity, 92% coverage of query (67.4 bits)

PHS_CHICK / O73930 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; cDcoH; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Gallus gallus (Chicken) (see paper)
    40% identity, 87% coverage of query (65.9 bits)

PHS_DROME / O76454 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Drosophila melanogaster (Fruit fly) (see paper)
    45% identity, 83% coverage of query (65.1 bits)

PHS_MOUSE / P61458 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Mus musculus (Mouse) (see paper)
    39% identity, 86% coverage of query (63.9 bits)

PCBD1 / P61457 Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) from Homo sapiens (see paper)
PHS_HUMAN / P61457 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Homo sapiens (Human) (see 5 papers)
PHS_RAT / P61459 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Rattus norvegicus (Rat) (see 7 papers)
    39% identity, 86% coverage of query (63.5 bits)

Q02I31 Putative pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Pseudomonas aeruginosa (strain UCBPP-PA14)
    31% identity, 94% coverage of query (63.2 bits)

1f93A / P61459 Crystal structure of a complex between the dimerization domain of hnf-1 alpha and the coactivator dcoh (see paper)
    39% identity, 86% coverage of query (62.4 bits)

1dcpA Dcoh, a bifunctional protein-binding transcriptional coactivator, complexed with biopterin
    40% identity, 83% coverage of query (60.5 bits)

PHS2_MOUSE / Q9CZL5 Pterin-4-alpha-carbinolamine dehydratase 2; PHS 2; 4-alpha-hydroxy-tetrahydropterin dehydratase 2; DcoH-like protein DCoHm; Dimerization cofactor of hepatocyte nuclear factor 1 from muscle; HNF-1-alpha dimerization cofactor; EC 4.2.1.96 from Mus musculus (Mouse) (see paper)
    42% identity, 74% coverage of query (59.3 bits)

PCBD2 / Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 (EC 4.2.1.96) from Homo sapiens (see 3 papers)
PHS2_HUMAN / Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2; PHS 2; 4-alpha-hydroxy-tetrahydropterin dehydratase 2; DcoH-like protein DCoHm; Dimerization cofactor of hepatocyte nuclear factor 1 from muscle; HNF-1-alpha dimerization cofactor; EC 4.2.1.96 from Homo sapiens (Human) (see paper)
Q9H0N5 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Homo sapiens (see paper)
    38% identity, 87% coverage of query (57.8 bits)

2v6tB / Q2Q449 Crystal structure of a complex of pterin-4a-carbinolamine dehydratase from toxoplasma gondii with 7,8-dihydrobiopterin (see paper)
    40% identity, 71% coverage of query (56.6 bits)

Q2Q449 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Toxoplasma gondii (see paper)
    40% identity, 71% coverage of query (56.6 bits)

PDL2_ARATH / Q6QJ72 Pterin-4-alpha-carbinolamine dehydratase 2, mitochondrial; 4-alpha-hydroxy-tetrahydropterin dehydratase; PCD/DCoH-like protein 2; EC 4.2.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    30% identity, 95% coverage of query (54.7 bits)

ATP1_ARATH / Q9LU63 Probable pterin-4-alpha-carbinolamine dehydratase, chloroplastic; 4-alpha-hydroxy-tetrahydropterin dehydratase; PCD/DCoH-like protein 1; Protein AIRP2 TARGET PROTEIN 1; Protein SDIR1-INTERACTING PROTEIN 1; EC 4.2.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    31% identity, 91% coverage of query (43.1 bits)

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Build an alignment for Dsui_3224 and 14 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory