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Searching for up to 100 curated homologs for Dsui_3451 FitnessBrowser__PS:Dsui_3451 (427 a.a.)

Found high-coverage hits (≥70%) to 10 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 2.A.1.53.2 / Q5ZUB4 The valine uptake permease, PhtJ (required for maximal growth in macrophages and Acanthamoeba castellanii) (see paper)
    30% identity, 91% coverage of query (161 bits)

TC 2.A.1.53.1 / Q5ZY33 The threonine uptake permease, PhtA (Sauer et al., 2005) (required for maximal growth in macrophages and Acanthamoeba castellanii) (see paper)
    31% identity, 93% coverage of query (157 bits)

Build an alignment

Build an alignment for Dsui_3451 and 2 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

TC 2.A.1.53.6 / I7I0I1 MFS uptake permease specific for pyrimidines, PhtC of 422 aas and 12 TMSs from Legionella pneumophila subsp. pneumophila
    27% identity, 92% coverage of query (135 bits)

TC 2.A.1.53.7 / I7HKH2 MFS uptake permease, probably specific for pyrimidines, PhtD of 427 aas and 12 TMSs from Legionella pneumophila subsp. pneumophila
    25% identity, 91% coverage of query (92.0 bits)

G6PT1_HUMAN / O43826 Glucose-6-phosphate exchanger SLC37A4; Glucose-5-phosphate transporter; Glucose-6-phosphate translocase; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG-19 from Homo sapiens (Human) (see 24 papers)
TC 2.A.1.4.5 / O43826 Microsomal (ER/Golgi) glucose-6-P:Pi antiporter (glycogen storage disease (GSD1b and 1c); Gierke''s disease protein) (SLC37A2 in mice, associated with white adipose tissue obesity and expressed at high levels in macrophage) (4 isoforms present in humans (Chen et al., 2008)) from Homo sapiens (Human) (see 23 papers)
SLC37A4 / RF|NP_001458.1 glucose-6-phosphate translocase from Homo sapiens
    24% identity, 81% coverage of query (53.5 bits)

ANTR2_ARATH / Q8GX78 Ascorbate transporter, chloroplastic; Phosphate transporter PHT4;4; AtPHT4;4; Probable anion transporter 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
    21% identity, 87% coverage of query (50.8 bits)

YidT / b3691 D-galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dgoT / P0AA76 D-galactonate:H+ symporter from Escherichia coli (strain K12) (see 11 papers)
DGOT_ECOLI / P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.14.7 / P0AA76 Galactonate transporter from Escherichia coli (see 4 papers)
    20% identity, 83% coverage of query (50.1 bits)

6e9nA / J7QAK3 E. Coli d-galactonate:proton symporter in the inward open form (see paper)
    20% identity, 83% coverage of query (49.7 bits)

ANTR1_ARATH / O82390 Sodium-dependent phosphate transport protein 1, chloroplastic; Anion transporter 1; Na(+)/PI cotransporter 1; Phosphate transporter PHT4;1; Sodium/phosphate cotransporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
O82390 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see 2 papers)
TC 2.A.1.14.22 / O82390 The chloroplast thylakoid Na+:phosphate symporter, ANTR1 (512aas) (Pavón et al., 2008). Residues essential for function have been identified from Arabidopsis thaliana (see 7 papers)
    23% identity, 87% coverage of query (47.8 bits)

6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form
    20% identity, 83% coverage of query (43.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory