Sites on a Tree

 

Searching for up to 100 curated homologs for EX31_RS25170 (46 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

8rd8Ba / A0A0M4TEZ6 8rd8Ba (see paper)
    84% identity, 96% coverage of query (74.7 bits)

8cd14 / P29436 8cd14 (see paper)
    84% identity, 96% coverage of query (73.6 bits)

7unw6 50S ribosomal protein L34
    84% identity, 96% coverage of query (73.6 bits)

7m4v1 / B7IBH8 A. Baumannii ribosome-eravacycline complex: 50s (see paper)
    82% identity, 96% coverage of query (69.3 bits)

SsaF / b3703 50S ribosomal subunit protein L34 from Escherichia coli K-12 substr. MG1655 (see 31 papers)
rpmH / P0A7P5 50S ribosomal subunit protein L34 from Escherichia coli (strain K12) (see 30 papers)
RL34_ECOLI / P0A7P5 Large ribosomal subunit protein bL34; 50S ribosomal protein L34 from Escherichia coli (strain K12) (see 8 papers)
8a3l1 / P0A7P5 8a3l1 (see paper)
    93% identity, 100% coverage of query (67.8 bits)

3bbx2 The hsp15 protein fitted into the low resolution cryo-em map of the 50s.Nc-tRNA.Hsp15 complex
    93% identity, 100% coverage of query (67.8 bits)

RL34_DEIRA / Q9RSH2 Large ribosomal subunit protein bL34; 50S ribosomal protein L34 from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see 6 papers)
7a0r2 / Q9RSH2 50s deinococcus radiodurans ribosome bounded with mycinamicin i (see paper)
    67% identity, 98% coverage of query (61.2 bits)

RL34_BACSU / P05647 Large ribosomal subunit protein bL34; 50S ribosomal protein L34 from Bacillus subtilis (strain 168) (see paper)
    70% identity, 96% coverage of query (59.3 bits)

3j3v2 Atomic model of the immature 50s subunit from bacillus subtilis (state i-a)
    70% identity, 96% coverage of query (59.3 bits)

8uua6 Cryo-em structure of the listeria innocua 50s ribosomal subunit in complex with hflxr (structure iii)
    70% identity, 93% coverage of query (57.4 bits)

5nrg2 / Q2FUQ0 The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with rb02 (see paper)
6dddP Structure of the 50s ribosomal subunit from methicillin resistant staphylococcus aureus in complex with the oxazolidinone antibiotic lzd-5 (see paper)
    66% identity, 96% coverage of query (57.0 bits)

6o8w4 / A0A1B4XSI4 6o8w4 (see paper)
    66% identity, 96% coverage of query (56.6 bits)

9c4g1 / A0A2B7IDI8 Cutibacterium acnes 50s ribosomal subunit with clindamycin bound (see paper)
    66% identity, 96% coverage of query (55.8 bits)

8crx1 30S ribosomal protein S17
    66% identity, 96% coverage of query (55.8 bits)

8p7x0 / P78006 8p7x0 (see paper)
    62% identity, 98% coverage of query (55.5 bits)

RL34_THET8 / P80340 Large ribosomal subunit protein bL34; 50S ribosomal protein L34 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
5a9zAd / P80340 of Thermous thermophilus ribosome bound to BipA-GDPCP (see paper)
    62% identity, 98% coverage of query (55.1 bits)

1vy4B7 50S ribosomal protein L36
    62% identity, 98% coverage of query (55.1 bits)

5myjB6 / A2RHL6 of 70S ribosome from Lactococcus lactis (see paper)
    64% identity, 96% coverage of query (54.7 bits)

5o60d Structure of the 50s large ribosomal subunit from mycobacterium smegmatis
    58% identity, 93% coverage of query (46.6 bits)

5mrcY / Q04598 of the yeast mitochondrial ribosome - Class A (see paper)
    55% identity, 87% coverage of query (44.3 bits)

RM34_YEAST / Q04598 Large ribosomal subunit protein bL34m; 54S ribosomal protein L34, mitochondrial; L34mt from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
    55% identity, 87% coverage of query (44.3 bits)

7msc2 / P9WH93 70SIC in complex with MtbEttA at Pre_R0 state (see paper)
    58% identity, 83% coverage of query (42.4 bits)

Build an alignment

Build an alignment for EX31_RS25170 and 22 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory