Searching for up to 100 curated homologs for Echvi_0304 FitnessBrowser__Cola:Echvi_0304 (282 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
8swtA / Q5LAA3 Structure of bacteroides fragilis pnp bound to transition state analog immucillin h and sulfate (see paper)
54% identity, 95% coverage of query (299 bits)
4m1eB / D5SMY7 Crystal structure of purine nucleoside phosphorylase i from planctomyces limnophilus dsm 3776, nysgrc target 029364.
52% identity, 95% coverage of query (288 bits)
4lnaA / D2QIK7 Crystal structure of purine nucleoside phosphorylase i from spirosoma linguale dsm 74, nysgrc target 029362
52% identity, 94% coverage of query (280 bits)
P46354 Purine nucleoside phosphorylase 1; PNP 1; Inosine phosphorylase; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase I; PNP I; Pu-NPase I; EC 2.4.2.1 from Bacillus subtilis (strain 168)
49% identity, 95% coverage of query (271 bits)
A0A3G5E8S8 purine-nucleoside phosphorylase (EC 2.4.2.1) from Aneurinibacillus migulanus (see paper)
48% identity, 95% coverage of query (259 bits)
PUNA_GEOSE / P77834 Purine nucleoside phosphorylase 1; PNP 1; Inosine phosphorylase; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase I; PNP I; Pu-NPase I; EC 2.4.2.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
P77834 purine-nucleoside phosphorylase (EC 2.4.2.1) from Geobacillus stearothermophilus (see paper)
48% identity, 95% coverage of query (259 bits)
8swuA / A0A0H2YR30 Structure of clostridium perfringens pnp bound to transition state analog immucillin h and sulfate (see paper)
45% identity, 96% coverage of query (245 bits)
Q72L69 purine-nucleoside phosphorylase (EC 2.4.2.1) from Thermus thermophilus (see paper)
45% identity, 95% coverage of query (240 bits)
1a9sA Bovine purine nucleoside phosphorylase complexed with inosine and sulfate
47% identity, 98% coverage of query (239 bits)
1a9qA Bovine purine nucleoside phosphorylase complexed with inosine
47% identity, 98% coverage of query (239 bits)
1a9oA / P55859 Bovine purine nucleoside phosphorylase complexed with phosphate (see paper)
47% identity, 98% coverage of query (238 bits)
P55859 purine-nucleoside phosphorylase (EC 2.4.2.1) from Bos taurus (see 13 papers)
51% identity, 88% coverage of query (238 bits)
1a9pA Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate
47% identity, 98% coverage of query (238 bits)
1b8nA Purine nucleoside phosphorylase
51% identity, 88% coverage of query (238 bits)
1b8oA Purine nucleoside phosphorylase
51% identity, 88% coverage of query (238 bits)
P55859 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Bos taurus (Bovine)
51% identity, 88% coverage of query (238 bits)
1a9tA Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate
51% identity, 88% coverage of query (238 bits)
1fxuA Purine nucleoside phosphorylase from calf spleen in complex with n(7)- acycloguanosine inhibitor and a phosphate ion
50% identity, 88% coverage of query (236 bits)
4nsnA / B2RKN6 Crystal structure of purine nucleoside phosphorylase from porphyromonas gingivalis atcc 33277, nysgrc target 030972, orthorhombic symmetry
49% identity, 92% coverage of query (235 bits)
PNPH_MOUSE / P23492 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Mus musculus (Mouse) (see 2 papers)
46% identity, 94% coverage of query (234 bits)
P85973 purine-nucleoside phosphorylase (EC 2.4.2.1) from Rattus norvegicus (see paper)
49% identity, 88% coverage of query (234 bits)
1lv8A Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit
55% identity, 76% coverage of query (232 bits)
4earA Crystal structure of purine nucleoside phosphorylase (w16y, w94y, w178y, h257w) mutant from human complexed with dadme-immg and phosphate
47% identity, 94% coverage of query (232 bits)
3d1vA / P00491 Crystal structure of human pnp complexed with 2-mercapto(3h) quinazolinone (see paper)
50% identity, 88% coverage of query (231 bits)
3inyA Crystal structure of human purine nucleoside phosphorylase in complex with 7-deazaguanine
50% identity, 88% coverage of query (231 bits)
1yryE Crystal structure of human pnp complexed with mesg
50% identity, 88% coverage of query (231 bits)
1v45E Crystal structure of human pnp complexed with 3-deoxyguanosine
50% identity, 88% coverage of query (231 bits)
1v41E Crystal structure of human pnp complexed with 8-azaguanine
50% identity, 88% coverage of query (231 bits)
1v3qE Structure of human pnp complexed with ddi
50% identity, 88% coverage of query (231 bits)
1v2hE Crystal structure of human pnp complexed with guanine
50% identity, 88% coverage of query (231 bits)
1rfgE Crystal structure of human purine nucleoside phosphorylase complexed with guanosine
50% identity, 88% coverage of query (231 bits)
1rctE Crystal structure of human purine nucleoside phosphorylase complexed with inosine
50% identity, 88% coverage of query (231 bits)
1pwyE Crystal structure of human pnp complexed with acyclovir
50% identity, 88% coverage of query (231 bits)
1pf7E Crystal structure of human pnp complexed with immucillin h
50% identity, 88% coverage of query (231 bits)
1rszA Structure of human purine nucleoside phosphorylase in complex with dadme-immucillin-h and sulfate
50% identity, 88% coverage of query (231 bits)
3phbE Crystal structure of human purine nucleoside phosphorylase in complex with dadme-immg
50% identity, 88% coverage of query (231 bits)
3k8qA Crystal structure of human purine nucleoside phosphorylase in complex with serme-immucillin h
50% identity, 88% coverage of query (231 bits)
3k8oE Crystal structure of human purine nucleoside phosphorylase in complex with datme-immh
50% identity, 88% coverage of query (231 bits)
3gb9A Human purine nucleoside phosphorylase double mutant e201q,n243d complexed with 2-fluoroadenine
50% identity, 88% coverage of query (231 bits)
7zsmA Human purine nucleoside phosphorylase in complex with js-375
50% identity, 88% coverage of query (231 bits)
PNP / P00491 purine nucleoside phosphorylase subunit (EC 2.4.2.1; EC 2.4.2.15) from Homo sapiens (see 9 papers)
PNPH_HUMAN / P00491 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Homo sapiens (Human) (see 6 papers)
P00491 purine-nucleoside phosphorylase (EC 2.4.2.1) from Homo sapiens (see 29 papers)
50% identity, 88% coverage of query (230 bits)
3ggsA Human purine nucleoside phosphorylase double mutant e201q,n243d complexed with 2-fluoro-2'-deoxyadenosine
50% identity, 88% coverage of query (230 bits)
7zspA Human purine nucleoside phosphorylase in complex with js-555
50% identity, 88% coverage of query (230 bits)
7zsoA Human purine nucleoside phosphorylase in complex with js-554
50% identity, 88% coverage of query (230 bits)
7zsnA Human purine nucleoside phosphorylase in complex with js-379
50% identity, 88% coverage of query (230 bits)
4ns1A Crystal structure of purine nucleoside phosphorylase from porphyromonas gingivalis atcc 33277, nysgrc target 30972
48% identity, 92% coverage of query (227 bits)
2qplA Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue
54% identity, 76% coverage of query (226 bits)
2ai2A Purine nucleoside phosphorylase from calf spleen
49% identity, 88% coverage of query (225 bits)
2ai1A Purine nucleoside phosphorylase from calf spleen
49% identity, 88% coverage of query (225 bits)
3lbaA / Q8DTU4 The crystal structure of smu.1229 from streptococcus mutans ua159 bound to hypoxanthine
50% identity, 83% coverage of query (224 bits)
3fucC Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue inhibitor 9-(5',5'-difluoro-5'- phosphonopentyl)-9-deazaguanine structure in a new space group with one full trimer in the asymmetric unit
49% identity, 88% coverage of query (224 bits)
3fucA Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue inhibitor 9-(5',5'-difluoro-5'- phosphonopentyl)-9-deazaguanine structure in a new space group with one full trimer in the asymmetric unit
49% identity, 88% coverage of query (224 bits)
2ai3A Purine nucleoside phosphorylase from calf spleen
49% identity, 88% coverage of query (223 bits)
PndA / b2407 xanthosine phosphorylase (EC 2.4.2.1; EC 2.4.2.15) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
xapA / P45563 xanthosine phosphorylase (EC 2.4.2.1; EC 2.4.2.15) from Escherichia coli (strain K12) (see 15 papers)
XAPA_ECOLI / P45563 Purine nucleoside phosphorylase 2; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase II; PNP II; Xanthosine phosphorylase; EC 2.4.2.1 from Escherichia coli (strain K12) (see 7 papers)
44% identity, 89% coverage of query (222 bits)
1yqqA / P45563 Escherichia coli purine nucleoside phosphorylase ii, the product of the xapa gene (see paper)
44% identity, 89% coverage of query (222 bits)
1yr3A Escherichia coli purine nucleoside phosphorylase ii, the product of the xapa gene
44% identity, 89% coverage of query (222 bits)
1v48A Calf spleen purine nucleoside phosphorylase (pnp) binary complex with 9-(5,5-difluoro-5-phosphonopenthyl)guanine
53% identity, 76% coverage of query (220 bits)
PNPH_ANOGA / A4Q998 Purine nucleoside phosphorylase; AgPNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Anopheles gambiae (African malaria mosquito) (see paper)
46% identity, 84% coverage of query (217 bits)
3odgA / Q66D48 Crystal structure of xanthosine phosphorylase bound with xanthine from yersinia pseudotuberculosis
42% identity, 96% coverage of query (216 bits)
2p4sA / A4Q998 Structure of purine nucleoside phosphorylase from anopheles gambiae in complex with dadme-immh (see paper)
46% identity, 84% coverage of query (216 bits)
7zslA Human purine nucleoside phosphorylase in complex with js-196
48% identity, 88% coverage of query (215 bits)
3khsB / Q5YBA4 Crystal structure of grouper iridovirus purine nucleoside phosphorylase (see paper)
41% identity, 96% coverage of query (213 bits)
3e0qC / Q9BMI9 Crystal structure of schistosoma mansoni purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor (see paper)
44% identity, 84% coverage of query (209 bits)
Q9BMI9 purine-nucleoside phosphorylase (EC 2.4.2.1) from Schistosoma mansoni (see 2 papers)
44% identity, 84% coverage of query (209 bits)
1tcvA Crystal structure of the purine nucleoside phosphorylase from schistosoma mansoni in complex with non-detergent sulfobetaine 195 and acetate
44% identity, 84% coverage of query (204 bits)
3fnqA Crystal structure of schistosoma purine nucleoside phosphorylase in complex with hypoxanthine
44% identity, 84% coverage of query (204 bits)
3f8wA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in complex with adenosine
44% identity, 84% coverage of query (204 bits)
3fazA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in complex with inosine
44% identity, 84% coverage of query (204 bits)
1tcuA Crystal structure of the purine nucleoside phosphorylase from schistosoma mansoni in complex with phosphate and acetate
44% identity, 84% coverage of query (204 bits)
3fb1A Crystal structure of purine nucleoside phosphorylase in complex with ribose-1-phosphate
44% identity, 84% coverage of query (204 bits)
3e9rB Crystal structure of purine nucleoside phosphorylase from schistosoma mansoni in complex with adenine
44% identity, 84% coverage of query (203 bits)
5ko6A / A0A0U3AGT1 Crystal structure of isoform 2 of purine nucleoside phosphorylase from schistosoma mansoni in complex with cytosine and ribose-1-phosphate (see paper)
41% identity, 95% coverage of query (202 bits)
3e9zA Crystal structure of purine nucleoside phosphorylase from schistosoma mansoni in complex with 6-chloroguanine
44% identity, 84% coverage of query (202 bits)
3djfA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in a complex with bcx-34
44% identity, 84% coverage of query (202 bits)
5tbvA Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with tubercidin
41% identity, 95% coverage of query (202 bits)
5tbuA Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with hypoxanthine
41% identity, 95% coverage of query (202 bits)
5tbtA Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with cytidine
41% identity, 95% coverage of query (202 bits)
6bj6A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 2-{[(s)- benzenesulfinyl]methyl}benzoic acid
41% identity, 95% coverage of query (202 bits)
6bifA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 1-(4-amino-2-hydroxyphenyl)ethan- 1-one
41% identity, 95% coverage of query (202 bits)
6bi9A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 1,2,5-trimethyl-1h-pyrrole-3- carboxylic acid
41% identity, 95% coverage of query (202 bits)
6bi1A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with (2r)-2-amino-3-(benzyloxy)propan- 1-ol
41% identity, 95% coverage of query (202 bits)
6bhbA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 2-aminopyrimidin-5-ol
41% identity, 95% coverage of query (202 bits)
6bfvA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 5-fluoro-1,2-dihydropyrimidin-2- one
41% identity, 95% coverage of query (202 bits)
6bb7A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 3-methyl-1,2-dihydropyridin-2-one
41% identity, 95% coverage of query (202 bits)
6b71A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with3-(4-chlorophenyl)-5h,6h- imidazo[2,1-b][1,3]thiazole
41% identity, 95% coverage of query (202 bits)
6b56A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 5-butylpyridine-2-carboxylic acid
41% identity, 95% coverage of query (202 bits)
6b4tA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 4-methylpyridin-2-ol
41% identity, 95% coverage of query (202 bits)
6b4qA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with pyridin-4-ol
41% identity, 95% coverage of query (202 bits)
6b3lA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 2,3-dihydro-1h-inden-2-amine
41% identity, 95% coverage of query (202 bits)
6b37A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 1,3-benzothiazol-2-ol
41% identity, 95% coverage of query (202 bits)
6b2lA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with piperidin-2-imine
41% identity, 95% coverage of query (202 bits)
6axaA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with (3s)-5-fluoro-3-hydroxy-1,3- dihydroindol-2-one
41% identity, 95% coverage of query (202 bits)
6aweA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 2-fluoro-6-(2-pyridin-2- ylethylamino)benzonitrile
41% identity, 95% coverage of query (202 bits)
6bj7A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 4-chloro-6-methylpyrimidin-2- amine
41% identity, 95% coverage of query (202 bits)
6b7iA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with (2s)-2-(3,5-difluorophenyl)-2- hydroxyacetic acid
41% identity, 95% coverage of query (202 bits)
5tbsA Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with adenine
41% identity, 95% coverage of query (202 bits)
6b6kA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3- one
41% identity, 95% coverage of query (202 bits)
Q6CSZ6 purine-nucleoside phosphorylase (EC 2.4.2.1) from Kluyveromyces lactis (see paper)
40% identity, 97% coverage of query (199 bits)
3iexA Schistosoma purine nucleoside phosphorylase in complex with guanosine
44% identity, 84% coverage of query (199 bits)
8swqA / Q6CSZ6 Structure of k. Lactis pnp bound to transition state analog dadme- immucillin h and sulfate (see paper)
40% identity, 94% coverage of query (198 bits)
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Lawrence Berkeley National Laboratory