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Searching for up to 100 curated homologs for Echvi_1123 FitnessBrowser__Cola:Echvi_1123 (343 a.a.)

Found high-coverage hits (≥70%) to 36 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YdgJ / b1624 putative oxidoreductase YdgJ from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ydgJ / RF|NP_416141 uncharacterized oxidoreductase ydgJ from Escherichia coli K12 (see 2 papers)
    44% identity, 97% coverage of query (275 bits)

iolW / O32223 scyllo-inositol dehydrogenase (NADP+) (EC 1.1.1.371) from Bacillus subtilis (strain 168) (see paper)
IOLW_BACSU / O32223 scyllo-inositol 2-dehydrogenase (NADP(+)) IolW; NADP(+)-dependent scyllo-inositol dehydrogenase 1; NADP(+)-dependent SI dehydrogenase 1; EC 1.1.1.371 from Bacillus subtilis (strain 168) (see 3 papers)
O32223 scyllo-inositol 2-dehydrogenase (NADP+) (EC 1.1.1.371) from Bacillus subtilis (see 2 papers)
    38% identity, 99% coverage of query (256 bits)

YhhX / b3440 putative oxidoreductase YhhX from Escherichia coli K-12 substr. MG1655 (see 6 papers)
yhhX / RF|NP_417897 uncharacterized oxidoreductase yhhX from Escherichia coli K12 (see 2 papers)
    36% identity, 95% coverage of query (196 bits)

Build an alignment

Build an alignment for Echvi_1123 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

3e18A / Q929L3 Crystal structure of NAD-binding protein from listeria innocua
    29% identity, 97% coverage of query (127 bits)

dfgE / I5AX46 C-glycoside oxidase (EC 1.1.3.50) from [Eubacterium] cellulosolvens 6 (see 2 papers)
    27% identity, 99% coverage of query (118 bits)

Q7NQL0 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase (EC 1.1.1.335) from Chromobacterium violaceum (see paper)
    26% identity, 99% coverage of query (95.9 bits)

3q2iA / Q7NQL0 Crystal structure of the wlba dehydrognase from chromobactrium violaceum in complex with nadh and udp-glcnaca at 1.50 a resolution (see paper)
    26% identity, 99% coverage of query (95.9 bits)

3q2kC / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
    23% identity, 99% coverage of query (90.1 bits)

5a03C / Q9A8X3 Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose (see paper)
    27% identity, 85% coverage of query (87.0 bits)

5a06A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with sorbitol
    27% identity, 85% coverage of query (87.0 bits)

5a05A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with maltotriose
    27% identity, 85% coverage of query (87.0 bits)

5a04A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glucose
    27% identity, 85% coverage of query (87.0 bits)

5a03E Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose
    27% identity, 85% coverage of query (87.0 bits)

5a02A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glycerol
    27% identity, 85% coverage of query (87.0 bits)

3q2kK / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
    22% identity, 99% coverage of query (85.9 bits)

7xr9A Crystal structure of dgpa with glucose
    27% identity, 80% coverage of query (82.4 bits)

dgpA / A0A3Q9WWX8 puerarin 3-dehydrogenase from human intestinal bacterium PUE (see 5 papers)
    28% identity, 80% coverage of query (82.0 bits)

7xreC / A0A3Q9WWX8 Crystal structure of dgpa
    27% identity, 80% coverage of query (79.3 bits)

6norA / Q70KD1 Crystal structure of gend2 from gentamicin a biosynthesis in complex with NAD (see paper)
    23% identity, 94% coverage of query (72.8 bits)

Q9DBB8 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Mus musculus (see paper)
    28% identity, 70% coverage of query (69.7 bits)

1evjA Crystal structure of glucose-fructose oxidoreductase (gfor) delta1-22 s64d
    22% identity, 84% coverage of query (67.4 bits)

slgS4 / CBA11563.1 NDP-hexose-3-ketoreductase from Streptomyces lydicus (see paper)
    26% identity, 78% coverage of query (66.6 bits)

Q93PS4 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase (EC 1.1.1.312) from Comamonas testosteroni (see paper)
    25% identity, 72% coverage of query (63.2 bits)

proD / Q75T27 α-hydroxy-γ-carboxymuconate ε-semialdehyde dehydrogenase subunit (EC 1.1.1.312) from Pseudomonas straminea (see 2 papers)
proD / BAD04059.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Pseudomonas straminea (see paper)
    25% identity, 72% coverage of query (62.0 bits)

NanY / b4280 KpLE2 phage-like element; 2,7-anhydro-N-acetylneuraminate hydratase from Escherichia coli K-12 substr. MG1655 (see 4 papers)
nanY / P39353 KpLE2 phage-like element; 2,7-anhydro-N-acetylneuraminate hydratase from Escherichia coli (strain K12) (see 6 papers)
YJHC_ECOLI / P39353 Uncharacterized oxidoreductase YjhC; EC 1.-.-.- from Escherichia coli (strain K12) (see paper)
    25% identity, 74% coverage of query (61.6 bits)

6o15A / P39353 Crystal structure of a putative oxidoreductase yjhc from escherichia coli in complex with NAD(h) (see paper)
    24% identity, 73% coverage of query (61.2 bits)

apsD / B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium radiobacter (strain K84 / ATCC BAA-868) (see paper)
APSD_RHIR8 / B9JK80 D-apiose dehydrogenase; EC 1.1.1.420 from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter) (see paper)
B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium tumefaciens (see paper)
    23% identity, 99% coverage of query (60.5 bits)

5uhwA / B9JK80 Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+ and magnesium
    23% identity, 98% coverage of query (60.1 bits)

5uiaA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, r-2,3-dihydroxyisovalerate and magnesium
    23% identity, 98% coverage of query (60.1 bits)

5ui9A Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, 2 -hydroxy-2-hydroxymethyl propanoic acid and magnesium
    23% identity, 98% coverage of query (60.1 bits)

5uhzA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, d-apionate and magnesium
    23% identity, 98% coverage of query (60.1 bits)

4l8vA / P26935 Crystal structure of a12k/d35s mutant myo-inositol dehydrogenase from bacillus subtilis with bound cofactor NADP (see paper)
    22% identity, 76% coverage of query (48.9 bits)

3nt5A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor and product inosose
    22% identity, 76% coverage of query (46.2 bits)

3nt4A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor nadh and inositol
    22% identity, 76% coverage of query (46.2 bits)

3nt2B Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
    22% identity, 76% coverage of query (46.2 bits)

3nt2A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
    22% identity, 76% coverage of query (46.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory