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Searching for up to 100 curated homologs for Echvi_1449 FitnessBrowser__Cola:Echvi_1449 (426 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

3e9kA Crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex
    48% identity, 96% coverage of query (396 bits)

Kynu / P70712 kynureninase subunit (EC 3.7.1.3) from Rattus norvegicus (see paper)
KYNU_RAT / P70712 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Rattus norvegicus (Rat) (see paper)
    47% identity, 97% coverage of query (395 bits)

2hzpA / Q16719 Crystal structure of homo sapiens kynureninase (see paper)
    48% identity, 96% coverage of query (395 bits)

KYNU_MOUSE / Q9CXF0 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Mus musculus (Mouse) (see paper)
    47% identity, 97% coverage of query (395 bits)

KYNU / Q16719 Kynureninase (EC 3.7.1.3) from Homo sapiens (see 5 papers)
KYNU_HUMAN / Q16719 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Homo sapiens (Human) (see 6 papers)
Q16719 kynureninase (EC 3.7.1.3) from Homo sapiens (see 4 papers)
    48% identity, 96% coverage of query (394 bits)

KYNU_CAEEL / Q18026 Kynureninase; Abnormal fluorescence under UV illumination; L-kynurenine hydrolase; EC 3.7.1.3 from Caenorhabditis elegans (see paper)
    44% identity, 97% coverage of query (367 bits)

KYNU_YEAST / Q05979 Kynureninase; Biosynthesis of nicotinic acid protein 5; L-kynurenine hydrolase; EC 3.7.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    43% identity, 97% coverage of query (360 bits)

B7XB98 kynureninase (EC 3.7.1.3) from Bombyx mori (see paper)
    33% identity, 98% coverage of query (252 bits)

RR42_RS15385 Kynureninase (EC 3.7.1.3) from Cupriavidus basilensis FW507-4G11
    32% identity, 96% coverage of query (198 bits)

PS417_23650 Kynureninase (EC 3.7.1.3) from Pseudomonas simiae WCS417
    32% identity, 96% coverage of query (194 bits)

1qz9A / P83788 The three dimensional structure of kynureninase from pseudomonas fluorescens (see paper)
    31% identity, 96% coverage of query (189 bits)

AO353_05935 Kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens FW300-N2E3
    31% identity, 96% coverage of query (189 bits)

kyn / P83788 kynureninase subunit (EC 3.7.1.3) from Pseudomonas fluorescens (see 2 papers)
KYNU_PSEFL / P83788 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Pseudomonas fluorescens (see paper)
    31% identity, 96% coverage of query (189 bits)

PfGW456L13_4288 Kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens GW456-L13
    31% identity, 96% coverage of query (184 bits)

BPHYT_RS16030 Kynureninase (EC 3.7.1.3) from Burkholderia phytofirmans PsJN
    31% identity, 96% coverage of query (182 bits)

Build an alignment

Build an alignment for Echvi_1449 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

sibQ / C0LTN1 kynureninase (EC 3.7.1.3) from Streptosporangium sibiricum (see paper)
    29% identity, 97% coverage of query (158 bits)

acmH / D6R244 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer from Streptomyces anulatus (see 4 papers)
    30% identity, 98% coverage of query (147 bits)

5xt6A A sulfur-transferring catalytic intermediate of sufs-sufu complex from bacillus subtilis
    21% identity, 94% coverage of query (54.7 bits)

SUFS_BACSU / O32164 Cysteine desulfurase SufS; EC 2.8.1.7 from Bacillus subtilis (strain 168) (see 8 papers)
O32164 cysteine desulfurase (EC 2.8.1.7) from Bacillus subtilis (see 2 papers)
    21% identity, 94% coverage of query (54.3 bits)

7cepA / O32164 Crystal structure of l-cycloserine-bound form of cysteine desulfurase sufs from bacillus subtilis (see paper)
    21% identity, 94% coverage of query (54.3 bits)

7xepA Sufs with l-propargylglycine
    21% identity, 94% coverage of query (54.3 bits)

7xetA Sufs with beta-cyano-l-alanine
    21% identity, 94% coverage of query (54.3 bits)

5j8qA Crystal structure of the cysteine desulfurase sufs of bacillus subtilis
    21% identity, 94% coverage of query (54.3 bits)

7xekA Sufs with d-cysteine for 6 h
    21% identity, 94% coverage of query (54.3 bits)

7xejA Sufs with d-cysteine for 5 min
    21% identity, 94% coverage of query (54.3 bits)

5zsoA Sufs from bacillus subtilis, soaked with l-cysteine for 90 sec
    21% identity, 94% coverage of query (54.3 bits)

7ceoA Crystal structure of pmp-bound form of cysteine desulfurase sufs from bacillus subtilis
    21% identity, 94% coverage of query (53.9 bits)

7xenA Sufs with l-penicillamine
    21% identity, 94% coverage of query (53.9 bits)

7cerA Crystal structure of d-cycloserine-bound form of cysteine desulfurase sufs h121a from bacillus subtilis
    21% identity, 94% coverage of query (53.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory