Searching for up to 100 curated homologs for Echvi_1450 FitnessBrowser__Cola:Echvi_1450 (451 a.a.)
Found high-coverage hits (≥70%) to 72 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
KMO_CYTH3 / Q11PP7 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Cytophaga hutchinsonii (strain ATCC 33406 / DSM 1761 / CIP 103989 / NBRC 15051 / NCIMB 9469 / D465) (see paper)
Q11PP7 kynurenine 3-monooxygenase (EC 1.14.13.9) from Cytophaga hutchinsonii (see paper)
44% identity, 96% coverage of query (379 bits)
Q8ISJ5 kynurenine 3-monooxygenase (EC 1.14.13.9) from Anopheles stephensi (see paper)
44% identity, 93% coverage of query (361 bits)
Q9MZS9 kynurenine 3-monooxygenase (EC 1.14.13.9) from Sus scrofa (see 2 papers)
43% identity, 94% coverage of query (357 bits)
KMO / O15229 kynurenine 3-monooxygenase (EC 1.14.13.9) from Homo sapiens (see 3 papers)
KMO_HUMAN / O15229 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Homo sapiens (Human) (see 8 papers)
O15229 kynurenine 3-monooxygenase (EC 1.14.13.9) from Homo sapiens (see 6 papers)
43% identity, 94% coverage of query (356 bits)
KMO_MOUSE / Q91WN4 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Mus musculus (Mouse) (see 3 papers)
Q91WN4 kynurenine 3-monooxygenase (EC 1.14.13.9) from Mus musculus (see 2 papers)
43% identity, 92% coverage of query (350 bits)
KMO_AEDAE / Q86PM2 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti) (see paper)
Q86PM2 kynurenine 3-monooxygenase (EC 1.14.13.9) from Aedes aegypti (see paper)
41% identity, 91% coverage of query (334 bits)
KMO_RAT / O88867 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Rattus norvegicus (Rat) (see 3 papers)
O88867 kynurenine 3-monooxygenase (EC 1.14.13.9) from Rattus norvegicus (see 2 papers)
42% identity, 90% coverage of query (331 bits)
6lkeA / O88867 In meso full-length rat kmo in complex with an inhibitor identified via DNA-encoded chemical library screening (see paper)
42% identity, 90% coverage of query (326 bits)
6lkdA In meso full-length rat kmo in complex with a pyrazoyl benzoic acid inhibitor
42% identity, 90% coverage of query (325 bits)
Q95NP6 kynurenine 3-monooxygenase (EC 1.14.13.9) from Tribolium castaneum (see paper)
44% identity, 90% coverage of query (323 bits)
5x68B / O15229 Crystal structure of human kmo (see paper)
43% identity, 81% coverage of query (305 bits)
orf19.5443 kynurenine 3-monooxygenase; EC 1.14.13.9 from Candida albicans (see 2 papers)
38% identity, 93% coverage of query (299 bits)
KMO_PSEFL / Q84HF5 Kynurenine 3-monooxygenase; PfKMO; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Pseudomonas fluorescens (see 5 papers)
Q84HF5 kynurenine 3-monooxygenase (EC 1.14.13.9) from Pseudomonas fluorescens (see 4 papers)
38% identity, 92% coverage of query (293 bits)
5fn0A / Q84HF5 Crystal structure of pseudomonas fluorescens kynurenine-3- monooxygenase (kmo) in complex with gsk180 (see paper)
37% identity, 92% coverage of query (289 bits)
5nakA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with the enzyme substrate l-kynurenine
37% identity, 92% coverage of query (289 bits)
6foxA The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with kynurenine
37% identity, 92% coverage of query (289 bits)
5x6qA Crystal structure of pseudomonas fluorescens kmo in complex with ro 61-8048
36% identity, 96% coverage of query (285 bits)
6fphA The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 1h
37% identity, 92% coverage of query (283 bits)
6fp1A The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 1
38% identity, 92% coverage of query (283 bits)
KMO_YEAST / P38169 Kynurenine 3-monooxygenase; Biosynthesis of nicotinic acid protein 4; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P38169 kynurenine 3-monooxygenase (EC 1.14.13.9) from Saccharomyces cerevisiae (see paper)
39% identity, 92% coverage of query (281 bits)
5nahA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-{5-chloro-6-[(1r)-1-(6-methylpyridazin-3-yl)ethoxy]-1,2- benzoxazol-3-yl}propanoic acid
37% identity, 92% coverage of query (281 bits)
5nagA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-{5-chloro-6-[(1r)-1-(pyridin-2-yl)ethoxy]-1,2-benzoxazol-3- yl}propanoic acid
37% identity, 92% coverage of query (281 bits)
5naeA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-{5-chloro-2-oxo-6-[(1r)-1-(pyridin-2-yl)ethoxy]-2,3-dihydro-1, 3-benzoxazol-3-yl}propanoic acid
37% identity, 92% coverage of query (281 bits)
5nabA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-(5-chloro-6-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl) propanoic acid
37% identity, 92% coverage of query (281 bits)
5mzkA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-[5-chloro-6-(cyclobutylmethoxy)-2-oxo-2,3-dihydro-1,3- benzoxazol-3-yl]propanoic acid
37% identity, 92% coverage of query (281 bits)
5mziA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-(5-chloro-6-cyclopropoxy-2-oxo-2,3-dihydro-1,3-benzoxazol-3- yl)propanoic acid
37% identity, 92% coverage of query (281 bits)
5mzcA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-(5-chloro-6-ethoxy-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl) propanoic acid
37% identity, 92% coverage of query (281 bits)
6fp0B The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 4
37% identity, 92% coverage of query (281 bits)
6foyA The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 9
37% identity, 92% coverage of query (280 bits)
6fozA The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 13
37% identity, 92% coverage of query (276 bits)
4j34B / P38169 Crystal structure of kynurenine 3-monooxygenase - truncated at position 394 plus his tag cleaved. (see paper)
39% identity, 84% coverage of query (251 bits)
sibC / C0LTL7 kynurenine 3-monooxygenase (EC 1.14.13.9) from Streptosporangium sibiricum (see paper)
34% identity, 96% coverage of query (242 bits)
5x6rA Crystal structure of saccharomyces cerevisiae kmo in complex with ro 61-8048
40% identity, 83% coverage of query (242 bits)
ACDD_ASPCN / A0A2I2F284 Kynurenine 3-monooxygenase acdD; Aspcandine biosynthesis gene cluster protein D; Kynurenine 3-hydroxylase acdD; EC 1.14.13.9 from Aspergillus candidus (see paper)
35% identity, 90% coverage of query (235 bits)
4j36B Cocrystal structure of kynurenine 3-monooxygenase in complex with upf 648 inhibitor(kmo-394upf)
41% identity, 73% coverage of query (228 bits)
ecm4 / Q0X0C0 (2S,3R)-4-(2-aminophenyl)-2-amino-3-hydroxy-4-oxobutanoate oxidoreductase from Streptomyces lasalocidi (see 2 papers)
31% identity, 90% coverage of query (215 bits)
vioC / Q9S3U9 violacein synthase (EC 1.14.13.224) from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) (see 3 papers)
VIOC_CHRVO / Q9S3U9 Violacein synthase; EC 1.14.13.224 from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) (see 2 papers)
Q9S3U9 violacein synthase (EC 1.14.13.224) from Chromobacterium violaceum (see 2 papers)
30% identity, 83% coverage of query (151 bits)
Build an alignment for Echvi_1450 and 37 homologs with ≥ 30% identity
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HPXO_ACIAD / Q6F6Y2 FAD-dependent urate hydroxylase; Flavoprotein urate hydroxylase; EC 1.14.13.113 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
27% identity, 84% coverage of query (86.7 bits)
AF001965 / O08453 3-hydroxy-2-methylpyridinecarboxylate dioxygenase monomer (EC 1.14.13.242) from Pseudomonas sp. MA-1 (see 5 papers)
25% identity, 78% coverage of query (73.6 bits)
PRHF_PENBI / A0A1E1FFL6 FAD-dependent monooxygenase prhF; Paraherquonin biosynthesis cluster protein F; EC 1.-.-.- from Penicillium brasilianum (see 2 papers)
24% identity, 76% coverage of query (73.2 bits)
5tukB / A0A0H4TFU4 Crystal structure of tetracycline destructase tet(51) (see paper)
23% identity, 83% coverage of query (72.4 bits)
AUSM_PENBI / A0A0F7TXA0 FAD-dependent monooxygenase ausM; Austinoid biosynthesis clusters protein M; EC 1.-.-.- from Penicillium brasilianum (see paper)
25% identity, 74% coverage of query (72.4 bits)
3allB / Q988D3 Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, mutant y270a
24% identity, 78% coverage of query (72.4 bits)
mlr6788 / Q988D3 3-hydroxy-2-methylpyridinecarboxylate monooxygenase monomer (EC 1.14.13.242) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 2 papers)
Q988D3 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase (EC 1.14.13.242) from Mesorhizobium loti (see 4 papers)
25% identity, 78% coverage of query (72.0 bits)
4jy3A Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-pyridoxic acid bound form
25% identity, 78% coverage of query (72.0 bits)
4h2qA Structure of mhpco-5hn complex
25% identity, 78% coverage of query (72.0 bits)
3gmcA Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase with substrate bound
25% identity, 76% coverage of query (71.2 bits)
tmuM / I7ASS7 trimethyluric acid monooxygenase (EC 1.14.13.212) from Pseudomonas sp. (strain CBB1) (see paper)
I7ASS7 1,3,7-trimethyluric acid 5-monooxygenase (EC 1.14.13.212) from Pseudomonas sp. (see 2 papers)
25% identity, 76% coverage of query (69.7 bits)
DPMAE_METAN / P9WEY1 FAD-dependent monooxygenase dpmaE; Diterpenoid pyrone biosynthesis cluster protein E; EC 1.-.-.- from Metarhizium anisopliae (Entomophthora anisopliae) (see paper)
25% identity, 79% coverage of query (67.8 bits)
creL / A0A0K2JKU1 3-amino-4-hydroxybenzoate 2-monooxygenase (EC 1.14.13.249) from Streptomyces cremeus (see paper)
AHBM_STRCM / A0A0K2JKU1 3-amino-4-hydroxybenzoate 2-monooxygenase; EC 1.14.13.249 from Streptomyces cremeus (see 2 papers)
A0A0K2JKU1 3-amino-4-hydroxybenzoate 2-monooxygenase (EC 1.14.13.249) from Streptomyces cremeus (see 2 papers)
21% identity, 79% coverage of query (66.6 bits)
nahW / Q9ZI64 salicylate hydroxylase (EC 1.14.13.1) from Stutzerimonas stutzeri (see paper)
24% identity, 73% coverage of query (64.7 bits)
ATMM_ASPFL / Q672V4 FAD-dependent monooxygenase atmM; Aflatrem synthesis protein M; EC 1.-.-.- from Aspergillus flavus (see 4 papers)
24% identity, 82% coverage of query (63.9 bits)
DPCHE_COLHI / H1VM35 FAD-dependent monooxygenase dpchE; Diterpenoid pyrone biosynthesis cluster protein E; EC 1.-.-.- from Colletotrichum higginsianum (strain IMI 349063) (Crucifer anthracnose fungus) (see paper)
24% identity, 72% coverage of query (63.2 bits)
AUSM_EMENI / C8VQ98 FAD-dependent monooxygenase ausM; Austinoid biosynthesis clusters protein M; EC 1.-.-.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 4 papers)
24% identity, 74% coverage of query (62.8 bits)
ADRH_PENRW / B6HV36 FAD-dependent monooxygenase adrH; Andrastin A biosynthesis cluster protein H; EC 1.-.-.- from Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum)
24% identity, 73% coverage of query (62.8 bits)
6HN3M_PSEFL / P86491 6-hydroxynicotinate 3-monooxygenase; 6-HNA monooxygenase; EC 1.14.13.114 from Pseudomonas fluorescens (see paper)
23% identity, 75% coverage of query (61.6 bits)
AUSM_ASPCI / A0A0U5CJU6 FAD-dependent monooxygenase ausM; Austinoid biosynthesis cluster protein M; EC 1.-.-.- from Aspergillus calidoustus (see 2 papers)
25% identity, 72% coverage of query (60.8 bits)
8gsmG / A0A167KUL3 Crystal structure of vibmo1
25% identity, 86% coverage of query (60.8 bits)
ubiL1 / Q3J6F1 2-methoxy-6-(all-trans-polyprenyl)phenol 4-hydroxylase (EC 1.14.13.240) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see 3 papers)
22% identity, 78% coverage of query (59.7 bits)
HPXO_MYCVP / A1TFU9 FAD-dependent urate hydroxylase; Flavoprotein urate hydroxylase; EC 1.14.13.113 from Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii) (see paper)
26% identity, 71% coverage of query (59.3 bits)
phzS / Q9HWG9 5-methylphenazine-1-carboxylate 1-monooxygenase (EC 1.14.13.218) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
PHZS_PSEAE / Q9HWG9 5-methylphenazine-1-carboxylate 1-monooxygenase; EC 1.14.13.218 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
Q9HWG9 5-methylphenazine-1-carboxylate 1-monooxygenase (EC 1.14.13.218) from Pseudomonas aeruginosa (see 3 papers)
24% identity, 84% coverage of query (58.9 bits)
ubiI / A0A0H2XCC9 4-hydroxy-3-polyprenylbenzoate 5-hydroxylase from Xanthomonas campestris pv. campestris (strain 8004) (see paper)
23% identity, 89% coverage of query (58.5 bits)
TET50_UNKP / A0A059WYP6 Flavin-dependent monooxygenase; Tetracycline destructase Tet(50); Tet(50); EC 1.14.13.- from Unknown prokaryotic organism (see 2 papers)
5tueA / A0A059WYP6 Crystal structure of tetracycline destructase tet(50) (see paper)
22% identity, 77% coverage of query (57.8 bits)
3c96A / Q9HWG9 Crystal structure of the flavin-containing monooxygenase phzs from pseudomonas aeruginosa. Northeast structural genomics consortium target par240
24% identity, 82% coverage of query (57.4 bits)
ubiL / Q2RMZ4 2-methoxy-6-(all-trans-nonaprenyl)phenol 4-hydroxylase (EC 1.14.13.240) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) (see paper)
UBIL_RHORT / Q2RMZ4 Ubiquinone hydroxylase UbiL; UQ hydroxylase; 2-polyprenyl-6-methoxyphenol hydroxylase; 2-polyprenylphenol hydroxylase; EC 1.14.13.-; EC 1.14.13.240 from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) (see paper)
22% identity, 70% coverage of query (55.5 bits)
EUPH_PHOSX / A0A4P8GF19 Flavin-dependent monooxygenase eupH; Eupenifeldin biosynthesis cluster protein H; EC 1.14.-.- from Phoma sp. (see 3 papers)
22% identity, 83% coverage of query (54.7 bits)
8x38A Crystal structure of decarboxylative vanillate 1-hydroxylase from phanerochaete chrysosporium
23% identity, 79% coverage of query (53.5 bits)
penE / A0A1B2CTA8 (2E)-4,8-dimethyl-4-hydroxynona-2,7-dienyl-quinolinone B epoxidase from Penicillium thymicola (see 2 papers)
PENE_PENTH / A0A1B2CTA8 FAD-dependent monooxygenase penE; Penigequinolones biosynthesis cluster protein E; EC 1.-.-.- from Penicillium thymicola (see 2 papers)
24% identity, 73% coverage of query (53.5 bits)
nicC / Q88FY2 6-hydroxynicotinate 3-monooxygenase (EC 1.14.13.114) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
6HN3M_PSEPK / Q88FY2 6-hydroxynicotinate 3-monooxygenase; 6-HNA monooxygenase; Nicotinate degradation protein C; EC 1.14.13.114 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
Q88FY2 6-hydroxynicotinate 3-monooxygenase (EC 1.14.13.114) from Pseudomonas putida (see paper)
23% identity, 80% coverage of query (48.1 bits)
CFOF_ASPCN / A0A2I2F2J4 Monooxygenase cfoF; Chlorflavonin biosynthesis cluster protein F; EC 1.14.-.- from Aspergillus candidus (see paper)
22% identity, 72% coverage of query (48.1 bits)
8uivA / Q88FY2 8uivA (see paper)
23% identity, 80% coverage of query (47.8 bits)
8uiqA 6-hydroxynicotinate 3-monooxygenase
23% identity, 79% coverage of query (47.0 bits)
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Lawrence Berkeley National Laboratory