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Searching for up to 100 curated homologs for Echvi_1677 FitnessBrowser__Cola:Echvi_1677 (756 a.a.)

Found high-coverage hits (≥70%) to 86 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AAO75446.1 α-glucosidase (BT0339;BT_0339) (EC 3.2.1.20) (see protein)
    61% identity, 99% coverage of query (967 bits)

AGDD_EMENI / Q5AW25 Alpha-xylosidase; EC 3.2.1.177 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
EAA62085.1 α-xylosidase (AgdD;AN7505) (EC 3.2.1.177) (see protein)
agdD alpha-xylosidase from Emericella nidulans (see paper)
    35% identity, 76% coverage of query (342 bits)

XYLQ_LACPE / P96793 Alpha-xylosidase XylQ; EC 3.2.1.177 from Lactiplantibacillus pentosus (Lactobacillus pentosus) (see paper)
AAC62251.1 α-xylosidase (XylQ) (EC 3.2.1.177) (see protein)
    35% identity, 73% coverage of query (303 bits)

A5FBI1 dextranase (EC 3.2.1.11) from Flavobacterium johnsoniae (see paper)
ABQ07434.1 dextranase/6-α-glucosyltransferase (Fjoh_4430) (EC 3.2.1.11|2.4.1.-) (see protein)
    32% identity, 71% coverage of query (268 bits)

6jr7A / A5FBI1 Flavobacterium johnsoniae gh31 dextranase, fjdex31a, complexed with glucose (see paper)
    32% identity, 71% coverage of query (268 bits)

Build an alignment

Build an alignment for Echvi_1677 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

A0A169PW02 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from uncultured microorganism (see paper)
    29% identity, 72% coverage of query (223 bits)

5zn7A Crystal structure of gh31 alpha-xylosidase from a soil metagenome complexed with xylose
    29% identity, 72% coverage of query (223 bits)

7p4dAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    28% identity, 72% coverage of query (219 bits)

7p4cAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    28% identity, 72% coverage of query (219 bits)

5npeA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with beta cyclophellitol aziridine probe ky358
    28% identity, 72% coverage of query (219 bits)

5npbA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol cyclosulfate probe me647
    28% identity, 72% coverage of query (219 bits)

4b9zA Crystal structure of agd31b, alpha-transglucosylase, complexed with acarbose
    28% identity, 72% coverage of query (219 bits)

4b9yA Crystal structure of apo agd31b, alpha-transglucosylase in glycoside hydrolase family 31
    28% identity, 72% coverage of query (219 bits)

5npdA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol aziridine probe cf021
    27% identity, 72% coverage of query (218 bits)

5npcA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with unreacted alpha cyclophellitol cyclosulfate probe me647
    27% identity, 72% coverage of query (218 bits)

5i24A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf021
    28% identity, 72% coverage of query (218 bits)

5i23A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf022
    28% identity, 72% coverage of query (218 bits)

4ba0A / B3PEE6 Crystal structure of agd31b, alpha-transglucosylase, complexed with 5f-alpha-glcf (see paper)
    28% identity, 71% coverage of query (217 bits)

OL4AG_CELJU / B3PEE6 Oligosaccharide 4-alpha-D-glucosyltransferase; Alpha-glucosidase 31B; CJAgd31B; EC 2.4.1.161 from Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) (see paper)
ACE84782.1 oligosaccharide α-1,4-transglucosylase 31B (CjAgd31B;CJA_3248) (Agd31B) (EC 2.4.1.161) (see protein)
    28% identity, 71% coverage of query (217 bits)

BAD34979.1 3-α-isomaltosyltransferase (CtsY;IMT) (EC 2.4.1.-) (see protein)
    28% identity, 73% coverage of query (217 bits)

BAQ19546.1 α-glucosidase (AG31A;BspAG31A) (EC 3.2.1.20) (see protein)
    28% identity, 71% coverage of query (212 bits)

Q9F234 alpha-glucosidase (EC 3.2.1.20) from Bacillus thermoamyloliquefaciens (see paper)
BAA76396.1 α-glucosidase II / oligo-α-1,6-glucosidase (BthG II) (EC 3.2.1.10|3.2.1.20) (see protein)
    27% identity, 71% coverage of query (202 bits)

AGLU_SACS9 / D0KQM8 Alpha-glucosidase; Maltase; EC 3.2.1.20 from Saccharolobus solfataricus (strain 98/2) (Sulfolobus solfataricus) (see paper)
D0KQM8 alpha-glucosidase (EC 3.2.1.20) from Saccharolobus solfataricus (see paper)
    25% identity, 76% coverage of query (197 bits)

P0CD66 alpha-glucosidase (EC 3.2.1.20) from Saccharolobus solfataricus (see 3 papers)
AAC38215.1 α-glucosidase with α-mannosidase activity (MalA;SsMalA;Sso1_0793) (EC 3.2.1.20|3.2.1.24) (see protein)
AAK43151.1 α-glucosidase (MalA;SSO3051) (EC 3.2.1.20) (see protein)
    25% identity, 75% coverage of query (197 bits)

xylS / Q9P999 α-D-xyloside xylohydrolase (EC 3.2.1.177) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 2 papers)
XYLS_SACS2 / Q9P999 Alpha-xylosidase; EC 3.2.1.177 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q9P999 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from Saccharolobus solfataricus (see 2 papers)
CAB99206.1 α-xylosidase (XylS;SS03022) (EC 3.2.1.177) (see protein)
    28% identity, 72% coverage of query (196 bits)

ABR26230.1 α-glucosidase (EC 3.2.1.20) (see protein)
    27% identity, 71% coverage of query (196 bits)

Q745T6 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB27 (see paper)
    30% identity, 72% coverage of query (195 bits)

Q4J9M3 oligo-1,6-glucosidase (EC 3.2.1.10); alpha-glucosidase (EC 3.2.1.20); glucan 1,3-alpha-glucosidase (EC 3.2.1.84) from Sulfolobus acidocaldarius (see paper)
AAY80507.1 α-glucosidase (MalA;Saci_1160) (EC 3.2.1.20) (see protein)
    25% identity, 76% coverage of query (179 bits)

4xppA Crystal structure of pedobacter saltans gh31 alpha-galactosidase complexed with d-galactose
    26% identity, 71% coverage of query (179 bits)

4xpqA / A0A0F7R6D6 Crystal structure of pedobacter saltans gh31 alpha-galactosidase complexed with l-fucose (see paper)
    26% identity, 71% coverage of query (178 bits)

4xpsA Crystal structure of the mutant d365a of pedobacter saltans gh31 alpha-galactosidase complexed with p-nitrophenyl-alpha- galactopyranoside
    26% identity, 71% coverage of query (176 bits)

F9VPH0 alpha-glucosidase (EC 3.2.1.20) from Sulfurisphaera tokodaii (see paper)
BAB67639.1 α-glucosidase (ST2525) (EC 3.2.1.20) (see protein)
    25% identity, 73% coverage of query (175 bits)

BAR72452.1 α-galactosidase (PsGal31A) (Gal31A) (EC 3.2.1.22) (see protein)
    26% identity, 71% coverage of query (173 bits)

Q9HLD0 alpha-glucosidase (EC 3.2.1.20) from Thermoplasma acidophilum (see paper)
CAC11443.1 α-glucosidase (AglA;Ta0298) (EC 3.2.1.20) (see protein)
    25% identity, 73% coverage of query (169 bits)

5nn6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-hydroxyethyl-1-deoxynojirimycin
    26% identity, 73% coverage of query (166 bits)

7p32AAA Lysosomal alpha-glucosidase
    26% identity, 73% coverage of query (165 bits)

5nn4A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-acetyl-cysteine
    26% identity, 73% coverage of query (165 bits)

smoI / A9CEZ0 sulfoquinovosidase (EC 3.2.1.199) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see 3 papers)
SQASE_AGRFC / A9CEZ0 Sulfoquinovosidase; SQase; AtSQase; SQ monooxygenase cluster protein I; EC 3.2.1.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see 2 papers)
    25% identity, 71% coverage of query (164 bits)

5nn8A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with acarbose
    26% identity, 73% coverage of query (164 bits)

8cb1A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-pnt-dnm 15
    26% identity, 73% coverage of query (164 bits)

5nn5A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with 1-deoxynojirimycin
    26% identity, 73% coverage of query (164 bits)

5kzwA / P10253 Crystal structure of human gaa
    26% identity, 73% coverage of query (162 bits)

5hjrA Murine endoplasmic reticulum alpha-glucosidase ii with bound covalent intermediate
    26% identity, 73% coverage of query (161 bits)

5hjoA Murine endoplasmic reticulum alpha-glucosidase ii with bound substrate analogue
    26% identity, 73% coverage of query (161 bits)

5iegA Murine endoplasmic reticulum alpha-glucosidase ii with n-9'- methoxynonyl-1-deoxynojirimycin
    26% identity, 73% coverage of query (161 bits)

7p2zAaA Lysosomal alpha-glucosidase
    26% identity, 73% coverage of query (161 bits)

8cb6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in covalent complex with tamra tagged 1,6-epi-cylcophellitol aziridine activity based probe
    26% identity, 73% coverage of query (160 bits)

5iefA / Q8BHN3 Murine endoplasmic reticulum alpha-glucosidase ii with n-butyl-1- deoxynojirimycin (see paper)
    26% identity, 73% coverage of query (159 bits)

7kb6A Co-crystal structure of alpha glucosidase with compound 7
    26% identity, 73% coverage of query (159 bits)

7k9tA Co-crystal structure of alpha glucosidase with compound 5
    26% identity, 73% coverage of query (159 bits)

7jtyA Co-crystal structure of alpha glucosidase with compound 1
    26% identity, 73% coverage of query (159 bits)

7k9qA Co-crystal structure of alpha glucosidase with compound 4
    26% identity, 73% coverage of query (159 bits)

7k9nA Co-crystal structure of alpha glucosidase with compound 2
    26% identity, 73% coverage of query (159 bits)

7kryA Co-crystal structure of alpha glucosidase with compound 11
    26% identity, 73% coverage of query (159 bits)

7kb8A Co-crystal structure of alpha glucosidase with compound 8
    26% identity, 73% coverage of query (159 bits)

7kadA Co-crystal structure of alpha glucosidase with compound 6
    26% identity, 73% coverage of query (159 bits)

7k9oA Co-crystal structure of alpha glucosidase with compound 3
    26% identity, 73% coverage of query (159 bits)

5ieeA Murine endoplasmic reticulum alpha-glucosidase ii with 1- deoxynojirimycin
    26% identity, 73% coverage of query (159 bits)

5iedA Murine endoplasmic reticulum alpha-glucosidase ii with castanospermine
    26% identity, 73% coverage of query (159 bits)

5h9oA Complex of murine endoplasmic reticulum alpha-glucosidase ii with d- glucose
    26% identity, 73% coverage of query (159 bits)

LYAG_HUMAN / P10253 Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; EC 3.2.1.20 from Homo sapiens (Human) (see 46 papers)
P10253 alpha-glucosidase (EC 3.2.1.20) from Homo sapiens (see 2 papers)
    25% identity, 73% coverage of query (158 bits)

CAA68763.1 α-glucosidase A (GAA) (lysosomal) (EC 3.2.1.20) (see protein)
    25% identity, 73% coverage of query (158 bits)

P70699 Lysosomal alpha-glucosidase; Acid maltase; EC 3.2.1.20 from Mus musculus (Mouse)
    25% identity, 73% coverage of query (158 bits)

AAH10210.1 α-glucosidase (GAA) (lysosomal) (EC 3.2.1.20) (see protein)
    25% identity, 73% coverage of query (157 bits)

LYAG_BOVIN / Q9MYM4 Lysosomal alpha-glucosidase; Acid maltase; EC 3.2.1.20 from Bos taurus (Bovine) (see paper)
AAF81637.1 acidic α-glucosidase (EC 3.2.1.20) (see protein)
    24% identity, 71% coverage of query (156 bits)

5ohyA A gh31 family sulfoquinovosidase in complex with aza-sugar inhibitor ifgsq
    25% identity, 71% coverage of query (154 bits)

7ofxB / A9CEZ0 Crystal structure of a gh31 family sulfoquinovosidase mutant d455n from agrobacterium tumefaciens in complex with sulfoquinovosyl glycerol (sqgro) (see paper)
    24% identity, 71% coverage of query (152 bits)

6c9xA / A5ZY13 The crystal structure of the alpha-glucosidase (gh 31) from ruminococcus obeum atcc 29174 in complex with voglibose
    24% identity, 74% coverage of query (152 bits)

ACU04898.1 α-galactosidase (PhGal31A;Phep_2697) (Gal31A) (EC 3.2.1.22) (see protein)
    24% identity, 73% coverage of query (152 bits)

3phaA The crystal structure of the w169y mutant of alpha-glucosidase (gh31 family) from ruminococcus obeum atcc 29174 in complex with acarbose
    24% identity, 74% coverage of query (152 bits)

5ohsA A gh31 family sulfoquinovosidase mutant d455n in complex with pnpsq
    24% identity, 71% coverage of query (152 bits)

6ca1A The crystal structure of the w169y mutant of alpha-glucosidase (gh 31) from ruminococcus obeum atcc 29174 in complex with miglitol
    24% identity, 74% coverage of query (152 bits)

3mkkA The crystal structure of the d307a mutant of glycoside hydrolase (family 31) from ruminococcus obeum atcc 29174 in complex with isomaltose
    23% identity, 74% coverage of query (150 bits)

BAD45910.1 α-glucosidase (Ong2;Ong-2;Ong3;OngX-H3;Os06g0675700) (EC 3.2.1.20) (see protein)
    24% identity, 78% coverage of query (144 bits)

3l4uA / O43451 Crystal complex of n-terminal human maltase-glucoamylase with de-o- sulfonated kotalanol (see paper)
    23% identity, 71% coverage of query (135 bits)

MGA_HUMAN / O43451 Maltase-glucoamylase; Alpha-1,4-glucosidase; EC 3.2.1.20 from Homo sapiens (Human) (see 8 papers)
    23% identity, 71% coverage of query (135 bits)

AAC39568.2 maltase-glucoamylase (MgaM;Mga;MGAML) (EC 3.2.1.20) (see protein)
    23% identity, 71% coverage of query (135 bits)

Q6L2X4 alpha-glucosidase (EC 3.2.1.20) from Picrophilus torridus (see paper)
AAT42677.1 α-glucosidase (AglA;PTO0092) (EC 3.2.1.20) (see protein)
    23% identity, 72% coverage of query (135 bits)

3l4zA Crystal complex of n-terminal human maltase-glucoamylase with salacinol
    23% identity, 71% coverage of query (135 bits)

3l4yA Crystal complex of n-terminal human maltase-glucoamylase with nr4-8ii
    23% identity, 71% coverage of query (135 bits)

3l4xA Crystal complex of n-terminal human maltase-glucoamylase with nr4-8
    23% identity, 71% coverage of query (135 bits)

3l4wA Crystal complex of n-terminal human maltase-glucoamylase with miglitol
    23% identity, 71% coverage of query (135 bits)

3l4vA Crystal complex of n-terminal human maltase-glucoamylase with kotalanol
    23% identity, 71% coverage of query (135 bits)

2qmjA Crystral structure of the n-terminal subunit of human maltase- glucoamylase in complex with acarbose
    23% identity, 71% coverage of query (135 bits)

3cttA Crystal complex of n-terminal human maltase-glucoamylase with casuarine
    23% identity, 71% coverage of query (135 bits)

3l4tA Crystal complex of n-terminal human maltase-glucoamylase with bj2661
    23% identity, 71% coverage of query (135 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory