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Searching for up to 100 curated homologs for Echvi_1798 FitnessBrowser__Cola:Echvi_1798 (287 a.a.)

Found high-coverage hits (≥70%) to 64 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q57VZ2 uridine phosphorylase (EC 2.4.2.3) from Trypanosoma brucei (see paper)
    32% identity, 90% coverage of query (148 bits)

3bjeA / Q57VZ2 Crystal structure of trypanosoma brucei nucleoside phosphorylase shows uridine phosphorylase activity (see paper)
    32% identity, 89% coverage of query (148 bits)

TK1479 / Q5JJC1 uridine phosphorylase (EC 2.4.2.2) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
UDP_THEKO / Q5JJC1 Uridine phosphorylase; UPase; UrdPase; EC 2.4.2.3 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    33% identity, 89% coverage of query (102 bits)

Build an alignment

Build an alignment for Echvi_1798 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q9YA34 uridine phosphorylase (EC 2.4.2.3) from Aeropyrum pernix (see 2 papers)
    29% identity, 88% coverage of query (80.5 bits)

A0A410UCT3 uridine phosphorylase (EC 2.4.2.3) from Phytophthora capsici (see paper)
    26% identity, 92% coverage of query (72.8 bits)

6k8pA / A0A410UCT3 Structural and catalytic analysis of two diverse uridine phosphorylases in the oomycete phytophthora capsici. (see paper)
    26% identity, 92% coverage of query (72.8 bits)

Sama_0412 Uridine phosphorylase (EC 2.4.2.3) from Shewanella amazonensis SB2B
    25% identity, 86% coverage of query (61.2 bits)

4daeA / O34925 Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 6-chloroguanosine (see paper)
    27% identity, 83% coverage of query (61.2 bits)

4yjkA Crystal structure of c212s mutant of shewanella oneidensis mr-1 uridine phosphorylase
    24% identity, 86% coverage of query (61.2 bits)

4danA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 2-fluoroadenosine
    27% identity, 83% coverage of query (61.2 bits)

4da0A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 2'-deoxyguanosine
    27% identity, 83% coverage of query (61.2 bits)

4darA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with tubercidin
    27% identity, 83% coverage of query (61.2 bits)

4dabA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with hypoxanthine
    27% identity, 83% coverage of query (61.2 bits)

4da8A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 8-bromoguanosine
    27% identity, 83% coverage of query (61.2 bits)

4da7A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with aciclovir
    27% identity, 83% coverage of query (61.2 bits)

4da6A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with ganciclovir
    27% identity, 83% coverage of query (61.2 bits)

4d9hA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with adenosine
    27% identity, 83% coverage of query (61.2 bits)

4d8vA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis at ph 4.2
    27% identity, 83% coverage of query (61.2 bits)

O34925 purine-nucleoside phosphorylase (EC 2.4.2.1) from Bacillus subtilis (see paper)
    27% identity, 83% coverage of query (60.8 bits)

4r2wF X-ray structure of uridine phosphorylase from shewanella oneidensis mr-1 in complex with uridine at 1.6 a resolution
    25% identity, 86% coverage of query (60.1 bits)

4r2wD / Q8E9X9 X-ray structure of uridine phosphorylase from shewanella oneidensis mr-1 in complex with uridine at 1.6 a resolution (see paper)
    25% identity, 86% coverage of query (59.7 bits)

SO4133 Uridine phosphorylase (EC 2.4.2.3) from Shewanella oneidensis MR-1
C7EWM3 uridine phosphorylase (EC 2.4.2.3) from Shewanella oneidensis (see 4 papers)
    25% identity, 86% coverage of query (59.7 bits)

Shewana3_3680 Uridine phosphorylase (EC 2.4.2.3) from Shewanella sp. ANA-3
    25% identity, 86% coverage of query (59.7 bits)

1vhwA Crystal structure of purine nucleoside phosphorylase with adenosine
    24% identity, 84% coverage of query (57.8 bits)

3pnsB Crystal structure of uridine phosphorylase complexed with uracil from vibrio cholerae o1 biovar el tor
    24% identity, 87% coverage of query (56.2 bits)

DEOD_SALTY / Q8ZJV7 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    25% identity, 86% coverage of query (54.7 bits)

6rcaA X-ray structure uridine phosphorylase from vibrio cholerae in complex with 2.2'-anhydrouridine at 1.34 a
    24% identity, 86% coverage of query (54.3 bits)

5efoE X-ray structure uridine phosphorylase from vibrio cholerae in complex with cytidine and cytosine at 1.63a.
    24% identity, 86% coverage of query (54.3 bits)

5c80A X-ray structure uridine phosphorylase from vibrio cholerae in complex with uridine at 2.24 a resolution
    24% identity, 86% coverage of query (54.3 bits)

4k6oA X-ray structure uridine phosphorylase from vibrio cholerae in complex with 6-methyluracil at 1.17 a resolution
    24% identity, 86% coverage of query (54.3 bits)

Q9K4U1 uridine phosphorylase (EC 2.4.2.3) from Vibrio cholerae (see 2 papers)
5efoB / Q9K4U1 X-ray structure uridine phosphorylase from vibrio cholerae in complex with cytidine and cytosine at 1.63a.
udp / CAB94933.1 uridine phosphorylase from Vibrio cholerae (see paper)
    24% identity, 86% coverage of query (53.9 bits)

4u2kD X-ray structure uridine phosphorylase from vibrio cholerae in complex with anticancer compound at 2.13 a resolution
    24% identity, 86% coverage of query (53.9 bits)

4u2kB X-ray structure uridine phosphorylase from vibrio cholerae in complex with anticancer compound at 2.13 a resolution
    24% identity, 86% coverage of query (53.9 bits)

4oglA X-ray structure uridine phosphorylase from vibrio cholerae in complex with thymine at 1.25 a resolution
    24% identity, 86% coverage of query (53.9 bits)

BWI76_RS01295 Uridine phosphorylase (EC 2.4.2.3) from Klebsiella michiganensis M5al
    26% identity, 86% coverage of query (53.5 bits)

3occF / B1JL34 Crystal structure of pnp with dadmeimmh from yersinia pseudotuberculosis
    24% identity, 84% coverage of query (52.8 bits)

1y1qC Crystal structure of the uridine phosphorylase from salmonella typhimurium in complex with uridine-5p-monophosphate and sulfate ion at 2.35a resolution
    25% identity, 87% coverage of query (52.4 bits)

A0A518Y5Z2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Helicobacter pylori (see paper)
    23% identity, 93% coverage of query (52.0 bits)

P56463 purine-nucleoside phosphorylase (EC 2.4.2.1) from Helicobacter pylori (see paper)
6f4wA / P56463 Crystal structure of h. Pylori purine nucleoside phosphorylase in complex with formycin a (see paper)
    23% identity, 93% coverage of query (52.0 bits)

5mx4C Crystal structure of h. Pylori purine nucleoside phosphorylase from clinical isolate hppnp-1
    23% identity, 93% coverage of query (52.0 bits)

1pr6A Escherichia coli purine nucleoside phosphorylase complexed with 9- beta-d-xylofuranosyladenine and phosphate/sulfate
    23% identity, 93% coverage of query (52.0 bits)

7op9A Purine nucleoside phosphorylase(deod-type) from h. Pylori with 2,6- dichloropurine
    23% identity, 93% coverage of query (52.0 bits)

7oozB Purine nucleoside phosphorylase(deod-type) from h. Pylori with 6- benzyloxo-2-chloropurine
    23% identity, 93% coverage of query (52.0 bits)

7ooyB Purine nucleoside phosphorylase(deod-type) from h. Pylori with 6- benzylthio-2-chloropurine
    23% identity, 93% coverage of query (52.0 bits)

5lu0A Crystal structure of h. Pylori referent strain in complex with po4
    23% identity, 93% coverage of query (52.0 bits)

Pup / b4384 purine nucleoside phosphorylase (EC 2.4.2.15; EC 2.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
deoD / P0ABP8 purine nucleoside phosphorylase (EC 2.4.2.15; EC 2.4.2.1) from Escherichia coli (strain K12) (see 30 papers)
DEOD_ECOLI / P0ABP8 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Escherichia coli (strain K12) (see 5 papers)
deoD / RF|NP_418801 purine nucleoside phosphorylase deoD-type; EC 2.4.2.1 from Escherichia coli K12 (see 13 papers)
    24% identity, 86% coverage of query (50.1 bits)

P0ABP9 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Escherichia coli O157:H7
    24% identity, 86% coverage of query (50.1 bits)

5iu6A Crystal structure of e.Coli purine nucleoside phosphorylase with 7- deazahypoxanthine
    24% identity, 86% coverage of query (50.1 bits)

5i3cA Crystal structure of e.Coli purine nucleoside phosphorylase with acycloguanosine
    24% identity, 86% coverage of query (50.1 bits)

3ut6A Crystal structure of e. Coli pnp complexed with po4 and formycin a
    24% identity, 86% coverage of query (50.1 bits)

1pw7A Crystal structure of e. Coli purine nucleoside phosphorylase complexed with 9-beta-d-arabinofuranosyladenine and sulfate/phosphate
    24% identity, 86% coverage of query (50.1 bits)

1pr0A Escherichia coli purine nucleoside phosphorylase complexed with inosine and phosphate/sulfate
    24% identity, 86% coverage of query (50.1 bits)

1pkeA Crystal structure of e. Coli purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine and sulfate/phosphate
    24% identity, 86% coverage of query (50.1 bits)

1pk9A Crystal structure of e. Coli purine nucleoside phosphorylase complexed with 2-fluoroadenosine and sulfate/phosphate
    24% identity, 86% coverage of query (50.1 bits)

1pk7A Crystal structure of e. Coli purine nucleoside phosphorylase complexed with adenosine and sulfate/phosphate
    24% identity, 86% coverage of query (50.1 bits)

1otyA Native pnp +allo
    24% identity, 86% coverage of query (50.1 bits)

1k9sD Purine nucleoside phosphorylase from e. Coli in complex with formycin a derivative and phosphate
    24% identity, 86% coverage of query (50.1 bits)

1k9sA Purine nucleoside phosphorylase from e. Coli in complex with formycin a derivative and phosphate
    24% identity, 86% coverage of query (50.1 bits)

1a69A Purine nucleoside phosphorylase in complex with formycin b and sulphate (phosphate)
    24% identity, 86% coverage of query (50.1 bits)

1pr4A Escherichia coli purine nucleoside phosphorylase complexed with 9- beta-d-ribofuranosyl-6-methylthiopurine and phosphate/sulfate
    24% identity, 86% coverage of query (49.7 bits)

1pr5A Escherichia coli purine nucleoside phosphorylase complexed with 7- deazaadenosine and phosphate/sulfate
    24% identity, 86% coverage of query (49.7 bits)

1ovgA M64v pnp +mepdr
    23% identity, 86% coverage of query (48.1 bits)

1ov6A M64v pnp + allo
    23% identity, 86% coverage of query (48.1 bits)

1oumA M64v pnp +talo
    23% identity, 86% coverage of query (48.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory