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Searching for up to 100 curated homologs for Echvi_1891 FitnessBrowser__Cola:Echvi_1891 (360 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

MOCS3_DROME / Q9VLJ8 Adenylyltransferase and sulfurtransferase MOCS3; Molybdenum cofactor synthesis protein 3; Ubiquitin activating enzyme 4; EC 2.7.7.80; EC 2.8.1.11 from Drosophila melanogaster (Fruit fly) (see paper)
    37% identity, 97% coverage of query (237 bits)

ptmS4 / A0A2R3ZBG9 [sulfur-carrier protein]--sulfur ligase from Streptomyces platensis (see 3 papers)
    37% identity, 93% coverage of query (223 bits)

UBA4_EMENI / O59954 Adenylyltransferase and sulfurtransferase uba4; Common component for nitrate reductase and xanthine dehydrogenase protein F; Ubiquitin-like protein activator 4; EC 2.7.7.80; EC 2.8.1.11 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
cnxF adenylyltransferase and sulfurtransferase uba4; EC 2.7.7.-; EC 2.8.1.- from Emericella nidulans (see 2 papers)
    34% identity, 99% coverage of query (207 bits)

moeZ / P9WMN7 [sulfur-carrier protein CysO]--sulfur ligase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
MOEZ_MYCTU / P9WMN7 Probable adenylyltransferase/sulfurtransferase MoeZ; EC 2.7.7.-; EC 2.8.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
    35% identity, 97% coverage of query (202 bits)

MOCS3 / O95396 MOCS3 adenylyltransferase/sulfurtransferase (EC 2.8.1.11; EC 2.7.7.80) from Homo sapiens (see 6 papers)
MOCS3_HUMAN / O95396 Adenylyltransferase and sulfurtransferase MOCS3; Molybdenum cofactor synthesis protein 3; Molybdopterin synthase sulfurylase; MPT synthase sulfurylase; EC 2.7.7.80; EC 2.8.1.11 from Homo sapiens (Human) (see 6 papers)
O95396 molybdopterin-synthase adenylyltransferase (EC 2.7.7.80); molybdopterin synthase sulfurtransferase (EC 2.8.1.11) from Homo sapiens (see 6 papers)
    35% identity, 98% coverage of query (194 bits)

6yubA / G0SC54 Crystal structure of uba4 from chaetomium thermophilum (see paper)
    31% identity, 98% coverage of query (177 bits)

UBA4_YEAST / P38820 Adenylyltransferase and sulfurtransferase UBA4; Needs CLA4 to survive protein 3; Ubiquitin-like protein activator 4; EC 2.7.7.-; EC 2.8.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
    30% identity, 96% coverage of query (169 bits)

Build an alignment

Build an alignment for Echvi_1891 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

UBA1_RABIT / Q29504 Ubiquitin-like modifier-activating enzyme 1; Ubiquitin-activating enzyme E1; EC 6.2.1.45 from Oryctolagus cuniculus (Rabbit) (see paper)
    23% identity, 70% coverage of query (52.0 bits)

UBA1_MOUSE / Q02053 Ubiquitin-like modifier-activating enzyme 1; Ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme E1 X; Ubiquitin-like modifier-activating enzyme 1 X; EC 6.2.1.45 from Mus musculus (Mouse) (see 2 papers)
Q02053 E1 ubiquitin-activating enzyme (EC 6.2.1.45) from Mus musculus (see paper)
    23% identity, 70% coverage of query (50.8 bits)

6dc6C / P22314 Crystal structure of human ubiquitin activating enzyme e1 (uba1) in complex with ubiquitin (see paper)
    23% identity, 70% coverage of query (50.4 bits)

UBA1Y_MOUSE / P31254 Ubiquitin-like modifier-activating enzyme 1 Y; Ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme E1 Y; EC 6.2.1.45 from Mus musculus (Mouse) (see paper)
    23% identity, 70% coverage of query (50.4 bits)

UBA1 / P22314 ubiquitin-activating enzyme E1 monomer (EC 6.2.1.45) from Homo sapiens (see 7 papers)
UBA1_HUMAN / P22314 Ubiquitin-like modifier-activating enzyme 1; Protein A1S9; Ubiquitin-activating enzyme E1; EC 6.2.1.45 from Homo sapiens (Human) (see 12 papers)
P22314 E2 ubiquitin-conjugating enzyme (EC 2.3.2.23); E1 ubiquitin-activating enzyme (EC 6.2.1.45); E1 NEDD8-activating enzyme (EC 6.2.1.64) from Homo sapiens (see 6 papers)
    23% identity, 70% coverage of query (50.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory