Searching for up to 100 curated homologs for Echvi_2001 FitnessBrowser__Cola:Echvi_2001 (311 a.a.)
Found high-coverage hits (≥70%) to 17 curated proteins.
Removed hits that are identical to the query, leaving 16
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CA265_RS23470 homoserine kinase (EC 2.7.1.39) from Pedobacter sp. GW460-11-11-14-LB5
52% identity, 98% coverage of query (306 bits)
N515DRAFT_0576 homoserine kinase (EC 2.7.1.39) from Dyella japonica UNC79MFTsu3.2
43% identity, 98% coverage of query (187 bits)
ThrB / b0003 homoserine kinase (EC 2.7.1.39) from Escherichia coli K-12 substr. MG1655 (see paper)
thrB / P00547 homoserine kinase (EC 2.7.1.39) from Escherichia coli (strain K12) (see 9 papers)
KHSE_ECOLI / P00547 Homoserine kinase; HK; HSK; EC 2.7.1.39 from Escherichia coli (strain K12) (see paper)
thrB / GB|BAB96580.2 homoserine kinase; EC 2.7.1.39 from Escherichia coli (see 2 papers)
37% identity, 89% coverage of query (168 bits)
thrB / CAA43213.1 homoserine kinase from Serratia marcescens (see paper)
35% identity, 91% coverage of query (166 bits)
hsk / Q8L7R2 homoserine kinase (EC 2.7.1.39) from Arabidopsis thaliana (see paper)
KHSE_ARATH / Q8L7R2 Homoserine kinase; Protein DOWNY MILDEW RESISTANT 1; EC 2.7.1.39 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q8L7R2 homoserine kinase (EC 2.7.1.39) from Arabidopsis thaliana (see 4 papers)
39% identity, 98% coverage of query (159 bits)
thrB / Q58504 homoserine kinase monomer (EC 2.7.1.39) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
1fwkA / Q58504 Crystal structure of homoserine kinase complexed with adp (see paper)
35% identity, 92% coverage of query (156 bits)
1h74B Crystal structure of homoserine kinase complexed with ile
35% identity, 92% coverage of query (156 bits)
1h74A Crystal structure of homoserine kinase complexed with ile
35% identity, 92% coverage of query (156 bits)
1h73A Crystal structure of homoserine kinase complexed with threonine
35% identity, 92% coverage of query (156 bits)
1h72C Crystal structure of homoserine kinase complexed with hse
35% identity, 92% coverage of query (156 bits)
KHSE_METMP / Q6M0H5 Homoserine kinase; HK; HSK; EC 2.7.1.39 from Methanococcus maripaludis (strain S2 / LL) (see paper)
38% identity, 92% coverage of query (153 bits)
Build an alignment for Echvi_2001 and 11 homologs with ≥ 30% identity
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KHSE_YEAST / P17423 Homoserine kinase; HK; HSK; EC 2.7.1.39 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
THR1 / AAA35154.1 homoserine kinase from Saccharomyces cerevisiae (see paper)
27% identity, 90% coverage of query (99.0 bits)
Q4Q6Y2 homoserine kinase (EC 2.7.1.39) from Leishmania major (see paper)
28% identity, 92% coverage of query (74.7 bits)
P07128 homoserine kinase (EC 2.7.1.39) from Corynebacterium glutamicum (see paper)
30% identity, 86% coverage of query (69.3 bits)
6cyzA / B1MLU6 Mycobacterial homoserine kinase thrb in complex with amppnp
30% identity, 85% coverage of query (53.1 bits)
P37550 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (EC 2.7.1.148) from Bacillus subtilis (see paper)
22% identity, 83% coverage of query (47.0 bits)
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Lawrence Berkeley National Laboratory