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Searching for up to 100 curated homologs for Echvi_2333 FitnessBrowser__Cola:Echvi_2333 (413 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ADCS / Q6TAS3 aminodeoxychorismate synthase (EC 2.6.1.85) from Solanum lycopersicum (see 2 papers)
ADCS_SOLLC / Q6TAS3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
    37% identity, 73% coverage of query (206 bits)

ADCS / Q8LPN3 aminodeoxychorismate synthase (EC 2.6.1.85) from Arabidopsis thaliana (see 2 papers)
ADCS_ARATH / Q8LPN3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; Protein EMBRYO DEFFECTIVE 1997; EC 2.6.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    33% identity, 88% coverage of query (206 bits)

para-aminobenzoate synthase component I / b1812 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
pabB / P05041 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli (strain K12) (see 17 papers)
PABB_ECOLI / P05041 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Escherichia coli (strain K12) (see 8 papers)
pabB / RF|NP_416326.1 para-aminobenzoate synthase, component 1; EC 2.6.1.85 from Escherichia coli K12 (see 8 papers)
    33% identity, 84% coverage of query (198 bits)

1k0eA / P05041 The crystal structure of aminodeoxychorismate synthase from formate grown crystals (see paper)
    32% identity, 84% coverage of query (190 bits)

7pi1DDD / P28820 7pi1DDD
    30% identity, 84% coverage of query (188 bits)

pabB / P28820 4-amino-4-deoxychorismate synthase (para-aminobenzoate synthase) (EC 2.6.1.123) from Bacillus subtilis (strain 168) (see paper)
PABB_BACSU / P28820 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Bacillus subtilis (strain 168) (see 2 papers)
P28820 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) (EC 2.6.1.123); aminodeoxychorismate synthase (EC 2.6.1.85) from Bacillus subtilis (see 2 papers)
pabB / GB|BAA05309.1 para-aminobenzoate synthase, component 1; EC 2.6.1.85 from Bacillus subtilis (see paper)
    30% identity, 84% coverage of query (188 bits)

trpE / Q08653 anthranilate synthase component I (EC 4.1.3.27) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    30% identity, 90% coverage of query (180 bits)

pabB para-aminobenzoate synthase, component I from Ralstonia solanacearum (see paper)
    33% identity, 85% coverage of query (177 bits)

phnA / P09785 PhnA anthranilate synthase subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
PHNA_PSEAE / P09785 Anthranilate synthase component 1, pyocyanine specific; AS; ASI; Anthranilate synthase alpha subunit, pyocyanine specific; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P09785 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
    30% identity, 80% coverage of query (174 bits)

TRPE_PSEPU / P20579 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    30% identity, 83% coverage of query (174 bits)

trpE / Q06128 anthranilate synthase α subunit (EC 4.1.3.27) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
TRPE_SACS2 / Q06128 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q06128 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Saccharolobus solfataricus (see paper)
    31% identity, 84% coverage of query (173 bits)

O94582 Probable anthranilate synthase component 1; Anthranilate synthase component I; EC 4.1.3.27 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    31% identity, 84% coverage of query (167 bits)

TryD / b1264 anthranilate synthase subunit TrpE (EC 4.1.3.27) from Escherichia coli K-12 substr. MG1655 (see paper)
trpE / P00895 anthranilate synthase subunit TrpE (EC 4.1.3.27) from Escherichia coli (strain K12) (see 10 papers)
TRPE_ECOLI / P00895 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Escherichia coli (strain K12) (see 3 papers)
    33% identity, 82% coverage of query (161 bits)

Build an alignment

Build an alignment for Echvi_2333 and 13 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

trpE / AAD09116.1 anthranilate synthase component I from Rhodobacter sphaeroides (see paper)
    28% identity, 82% coverage of query (161 bits)

1k0gA The crystal structure of aminodeoxychorismate synthase from phosphate grown crystals
    30% identity, 84% coverage of query (161 bits)

1k0gB / P05041 The crystal structure of aminodeoxychorismate synthase from phosphate grown crystals (see paper)
    30% identity, 84% coverage of query (160 bits)

TRPE_SALTY / P00898 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
    31% identity, 82% coverage of query (160 bits)

1i7sA Anthranilate synthase from serratia marcescens in complex with its end product inhibitor l-tryptophan
    32% identity, 82% coverage of query (160 bits)

1i7qA / P00897 Anthranilate synthase from s. Marcescens (see paper)
    32% identity, 82% coverage of query (159 bits)

1i1qA / P00898 Structure of the cooperative allosteric anthranilate synthase from salmonella typhimurium (see paper)
    31% identity, 82% coverage of query (159 bits)

TRPE_YEAST / P00899 Anthranilate synthase component 1; Anthranilate synthase component I; EC 4.1.3.27 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    30% identity, 84% coverage of query (159 bits)

Q9YGB3 anthranilate synthase (EC 4.1.3.27) from Thermococcus kodakarensis (see paper)
    30% identity, 71% coverage of query (153 bits)

TRPE_SERMA / P00897 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Serratia marcescens (see paper)
P00897 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Serratia marcescens (see paper)
    31% identity, 82% coverage of query (153 bits)

trpE anthranilate synthase component I; EC 4.1.3.27 from Leptospira biflexa serovar Patoc (see paper)
    28% identity, 71% coverage of query (131 bits)

5jy9B / A1JTF3 An iron-bound structure of the salicylate synthase irp9 (see paper)
    23% identity, 76% coverage of query (71.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory