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Searching for up to 100 curated homologs for Echvi_2468 FitnessBrowser__Cola:Echvi_2468 (316 a.a.)

Found high-coverage hits (≥70%) to 56 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ARGI_BACCD / P53608 Arginase; EC 3.5.3.1 from Bacillus caldovelox (see paper)
P53608 arginase (EC 3.5.3.1) from [Bacillus] caldovelox (see paper)
1cevA / P53608 Arginase from bacillus caldovelox, native structure at ph 5.6 (see paper)
    34% identity, 97% coverage of query (162 bits)

argI / P39138 arginase (EC 3.5.3.1) from Bacillus subtilis (strain 168) (see 3 papers)
ARGI_BACSU / P39138 Arginase; EC 3.5.3.1 from Bacillus subtilis (strain 168) (see 2 papers)
P39138 arginase (EC 3.5.3.1) from Bacillus subtilis (see paper)
    35% identity, 97% coverage of query (162 bits)

6dktA Crystal structure of arginase from bacillus subtilis
    35% identity, 97% coverage of query (162 bits)

6nfpD 1.7 angstrom resolution crystal structure of arginase from bacillus subtilis subsp. Subtilis str. 168
    35% identity, 97% coverage of query (161 bits)

6nfpA / P39138 1.7 angstrom resolution crystal structure of arginase from bacillus subtilis subsp. Subtilis str. 168
    35% identity, 97% coverage of query (160 bits)

5cevA Arginase from bacillus caldevelox, l-lysine complex
    34% identity, 96% coverage of query (160 bits)

4cevA Arginase from bacillus caldevelox, l-ornithine complex
    34% identity, 96% coverage of query (160 bits)

3cevA Arginase from bacillus caldevelox, complexed with l-arginine
    34% identity, 96% coverage of query (160 bits)

2cevB Arginase from bacillus caldevelox, native structure at ph 8.5
    34% identity, 96% coverage of query (160 bits)

A4IJM8 arginase (EC 3.5.3.1) from Geobacillus thermodenitrificans (see paper)
    33% identity, 97% coverage of query (159 bits)

Ac3H11_701 Arginase (EC 3.5.3.1) from Acidovorax sp. GW101-3H11
    33% identity, 96% coverage of query (153 bits)

6nbkA / W8YSI5 Crystal structure of arginase from bacillus cereus
    31% identity, 97% coverage of query (146 bits)

N515DRAFT_0348 Arginase (EC 3.5.3.1) from Dyella japonica UNC79MFTsu3.2
    32% identity, 96% coverage of query (144 bits)

Q6WVP6 arginase (EC 3.5.3.1) from Schistosoma mansoni (see paper)
    39% identity, 72% coverage of query (142 bits)

ARGI1_MOUSE / Q61176 Arginase-1; Liver-type arginase; Type I arginase; EC 3.5.3.1 from Mus musculus (Mouse) (see 10 papers)
Q61176 arginase (EC 3.5.3.1) from Mus musculus (see paper)
    35% identity, 78% coverage of query (140 bits)

A0A1S3R1W2 arginase (EC 3.5.3.1) from Salmo salar (see paper)
    33% identity, 83% coverage of query (137 bits)

6dktE / P39138 Crystal structure of arginase from bacillus subtilis
    32% identity, 97% coverage of query (137 bits)

A0A060YSI8 arginase (EC 3.5.3.1) from Oncorhynchus mykiss (see paper)
    33% identity, 83% coverage of query (136 bits)

U6BQJ3 arginase (EC 3.5.3.1) from Heteropneustes fossilis (see 2 papers)
    34% identity, 76% coverage of query (134 bits)

A0A1P8DAN3 arginase (EC 3.5.3.1) from Oncorhynchus mykiss (see paper)
    34% identity, 76% coverage of query (133 bits)

C0H9C1 arginase (EC 3.5.3.1) from Salmo salar (see paper)
    33% identity, 83% coverage of query (132 bits)

5zeeB / C4LSS0 Crystal structure of entamoeba histolytica arginase in complex with n(omega)-hydroxy-l-arginine (noha) at 1.74 a (see paper)
    32% identity, 78% coverage of query (132 bits)

ARGI_ENTH1 / C4LSS0 Arginase; EhArg; EC 3.5.3.1 from Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM) (see 3 papers)
C4LSS0 arginase (EC 3.5.3.1) from Entamoeba histolytica (see paper)
    32% identity, 78% coverage of query (132 bits)

5zehA Crystal structure of entamoeba histolytica arginase in complex with l- ornithine at 2.35 a
    32% identity, 78% coverage of query (132 bits)

5zefA Crystal structure of entamoeba histolytica arginase in complex with l- norvaline at 2.01 a
    32% identity, 78% coverage of query (132 bits)

1hqgA Crystal structure of the h141c arginase variant complexed with products ornithine and urea
    35% identity, 78% coverage of query (131 bits)

ARGI_NEUCR / P33280 Arginase; EC 3.5.3.1 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see paper)
    33% identity, 75% coverage of query (128 bits)

ARGI1_XENLA / P30759 Arginase-1; Arginase, hepatic; Type I arginase; EC 3.5.3.1 from Xenopus laevis (African clawed frog) (see paper)
    35% identity, 73% coverage of query (124 bits)

A0A145YEM9 arginase (EC 3.5.3.1) from Leishmania infantum (see paper)
    31% identity, 77% coverage of query (123 bits)

Build an alignment

Build an alignment for Echvi_2468 and 29 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

O25949 arginase (EC 3.5.3.1) from Helicobacter pylori (see paper)
    29% identity, 91% coverage of query (122 bits)

ARGI_KLULA / Q6CLS8 Arginase; EC 3.5.3.1 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) (see paper)
    32% identity, 72% coverage of query (121 bits)

4g3hC / O25949 Crystal structure of helicobacter pylori arginase
    29% identity, 91% coverage of query (121 bits)

car3 / RF|NP_593549.1 arginase Aru1; EC 3.5.3.1 from Schizosaccharomyces pombe (see paper)
    30% identity, 77% coverage of query (119 bits)

CAR1 / P00812 arginase subunit (EC 3.5.3.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
ARGI_YEAST / P00812 Arginase; EC 3.5.3.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    32% identity, 76% coverage of query (117 bits)

car1 / RF|NP_595133.1 arginase Car1; EC 3.5.3.1 from Schizosaccharomyces pombe (see 3 papers)
    31% identity, 76% coverage of query (117 bits)

ARGI_PLAF7 / Q8I384 Arginase; PFA; PfArg; EC 3.5.3.1 from Plasmodium falciparum (isolate 3D7) (see 4 papers)
Q8I384 arginase (EC 3.5.3.1) from Plasmodium falciparum 3D7 (see 2 papers)
    30% identity, 87% coverage of query (110 bits)

ARGI_PLABA / A0A509AF89 Arginase; EC 3.5.3.1 from Plasmodium berghei (strain Anka) (see 3 papers)
    34% identity, 70% coverage of query (107 bits)

3mmrA / Q8I384 Structure of plasmodium falciparum arginase in complex with abh (see paper)
    30% identity, 96% coverage of query (106 bits)

3sl1A Crystal structure of p. Falciparum arginase complexed with 2-amino-6- borono-2-methylhexanoic acid
    30% identity, 96% coverage of query (106 bits)

3sl0A Crystal structure of p. Falciparum arginase complexed with 2-amino-6- borono-2-(difluoromethyl)hexanoic acid
    30% identity, 96% coverage of query (106 bits)

7esrA / P73270 Crystal structure of synechocystis sp pcc6803 guanidinium hydrolase (r32) (see paper)
    27% identity, 71% coverage of query (77.8 bits)

gdmH / P73270 Ni2+-dependent guanidine hydrolase monomer from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
    27% identity, 71% coverage of query (77.8 bits)

3m1rD / P42068 The crystal structure of formimidoylglutamase from bacillus subtilis subsp. Subtilis str. 168
    26% identity, 75% coverage of query (71.6 bits)

HUTG_BACSU / P42068 Formimidoylglutamase; Formiminoglutamase; Formiminoglutamate hydrolase; N-formimino-L-glutamate formiminohydrolase; EC 3.5.3.8 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 75% coverage of query (71.2 bits)

SPEBH_THET2 / Q72JK8 N(1)-aminopropylagmatine ureohydrolase; Protein SpeB homolog; EC 3.5.3.24 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
    24% identity, 74% coverage of query (65.1 bits)

Q8YUM9 agmatinase (EC 3.5.3.11) from Anabaena sp. (see paper)
    27% identity, 71% coverage of query (64.7 bits)

1gq6B / P0DJQ3 Proclavaminate amidino hydrolase from streptomyces clavuligerus (see paper)
    25% identity, 70% coverage of query (64.3 bits)

pah / P0DJQ3 proclavaminate amidino hydrolase subunit (EC 3.5.3.22) from Streptomyces clavuligerus (see paper)
PAH_STRCL / P0DJQ3 Proclavaminate amidinohydrolase; Proclavaminic acid amidino hydrolase; EC 3.5.3.22 from Streptomyces clavuligerus (see paper)
    25% identity, 70% coverage of query (63.9 bits)

TTHA1129 / Q5SJ85 aminopropylagmatine ureohydrolase (EC 3.5.3.24) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
SEPBH_THET8 / Q5SJ85 N(1)-aminopropylagmatine ureohydrolase; Protein SpeB homolog; EC 3.5.3.24 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
Q5SJ85 N1-aminopropylagmatine ureohydrolase (EC 3.5.3.24) from Thermus thermophilus (see paper)
    23% identity, 74% coverage of query (63.5 bits)

GPUA_PSEAE / Q9I6K2 Guanidinopropionase; EC 3.5.3.17 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I6K2 Guanidinopropionase (EC 3.5.3.17) from Pseudomonas aeruginosa (see paper)
    27% identity, 71% coverage of query (62.0 bits)

3niqA Crystal structure of pseudomonas aeruginosa guanidinopropionase
    27% identity, 71% coverage of query (62.0 bits)

3nipB / Q9I6K2 Crystal structure of pseudomonas aeruginosa guanidinopropionase complexed with 1,6-diaminohexane (see paper)
    27% identity, 71% coverage of query (62.0 bits)

3pzlB / Q97BB8 The crystal structure of agmatine ureohydrolase of thermoplasma volcanium
    24% identity, 75% coverage of query (60.5 bits)

SPEB_METJA / Q57757 Agmatinase; EC 3.5.3.11 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q57757 agmatinase (EC 3.5.3.11) from Methanocaldococcus jannaschii (see paper)
    24% identity, 74% coverage of query (57.0 bits)

W8R465 guanidinobutyrase (EC 3.5.3.7) from Aspergillus niger (see paper)
    25% identity, 73% coverage of query (53.5 bits)

3lhlA / Q18A84 Crystal structure of a putative agmatinase from clostridium difficile
    24% identity, 74% coverage of query (48.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory