Searching for up to 100 curated homologs for Echvi_2531 FitnessBrowser__Cola:Echvi_2531 (757 a.a.)
Found high-coverage hits (≥70%) to 50 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q8RP87 aconitate hydratase (EC 4.2.1.3) from Bacteroides fragilis (see paper)
65% identity, 99% coverage of query (1011 bits)
ACON_CAEEL / P34455 Probable aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Caenorhabditis elegans (see paper)
63% identity, 98% coverage of query (927 bits)
ACON_EMENI / C8VG90 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; Homocitrate dehydratase; EC 4.2.1.3; EC 4.2.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
60% identity, 98% coverage of query (922 bits)
ACON_YEAST / P19414 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P19414 aconitate hydratase (EC 4.2.1.3) from Saccharomyces cerevisiae (see 2 papers)
60% identity, 98% coverage of query (919 bits)
Aco / O74699 aconitase from Aspergillus terreus (see paper)
59% identity, 98% coverage of query (915 bits)
ACON_ASPFU / Q4WLN1 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; Homocitrate dehydratase; EC 4.2.1.3; EC 4.2.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
61% identity, 97% coverage of query (914 bits)
5acnA / P16276 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal (see paper)
60% identity, 98% coverage of query (912 bits)
ACON_PIG / P16276 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) (see 4 papers)
60% identity, 98% coverage of query (911 bits)
ACON_BOVIN / P20004 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) (see paper)
60% identity, 98% coverage of query (910 bits)
ACON_SCHPO / O13966 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
60% identity, 98% coverage of query (910 bits)
1b0kA S642a:fluorocitrate complex of aconitase
60% identity, 98% coverage of query (910 bits)
ACO2 / Q99798 mitochondrial aconitate hydratase from Homo sapiens (see 7 papers)
ACON_HUMAN / Q99798 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Homo sapiens (Human) (see 2 papers)
Q99798 aconitate hydratase (EC 4.2.1.3) from Homo sapiens (see paper)
60% identity, 98% coverage of query (908 bits)
8acnA Crystal structures of aconitase with isocitrate and nitroisocitrate bound
60% identity, 98% coverage of query (908 bits)
1fghA Complex with 4-hydroxy-trans-aconitate
60% identity, 98% coverage of query (908 bits)
1amjA Steric and conformational features of the aconitase mechanism
60% identity, 98% coverage of query (908 bits)
1amiA Steric and conformational features of the aconitase mechanism
60% identity, 98% coverage of query (908 bits)
1acoA Crystal structure of aconitase with transaconitate bound
60% identity, 98% coverage of query (908 bits)
ACON_RAT / Q9ER34 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Rattus norvegicus (Rat) (see paper)
Q9ER34 aconitate hydratase (EC 4.2.1.3) from Rattus norvegicus (see 3 papers)
60% identity, 98% coverage of query (907 bits)
1nisA Crystal structure of aconitase with trans-aconitate and nitrocitrate bound
60% identity, 98% coverage of query (906 bits)
ACO1 aconitate hydratase; EC 4.2.1.3 from Candida albicans (see 2 papers)
60% identity, 98% coverage of query (905 bits)
Q99KI0 aconitate hydratase (EC 4.2.1.3) from Mus musculus (see paper)
60% identity, 98% coverage of query (905 bits)
ACON2_YEAST / P39533 Homocitrate dehydratase, mitochondrial; Aconitase 2; EC 4.2.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
54% identity, 97% coverage of query (794 bits)
ACON2_SCHPO / Q9P7D4 Aconitase-ribosomal protein bL21m fusion protein; EC 4.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
Q9P7D4 aconitate hydratase (EC 4.2.1.3) from Schizosaccharomyces pombe (see paper)
53% identity, 98% coverage of query (788 bits)
ACON2_ASPFU / Q4WJ90 Putative aconitate hydratase, mitochondrial; Aconitase 2; EC 4.2.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
52% identity, 98% coverage of query (742 bits)
ACON2_EMENI / Q5B6D6 Putative aconitate hydratase, mitochondrial; Aconitase 2; EC 4.2.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
50% identity, 98% coverage of query (738 bits)
Build an alignment for Echvi_2531 and 25 homologs with ≥ 30% identity
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ACO2M_ARATH / Q94A28 Aconitate hydratase 2, mitochondrial; Aconitase 2; mACO2; Citrate hydro-lyase 2; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
29% identity, 86% coverage of query (216 bits)
ACO1 / Q42560 aconitase from Arabidopsis thaliana (see paper)
ACO1_ARATH / Q42560 Aconitate hydratase 1; Aconitase 1; Citrate hydro-lyase 1; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q42560 aminocyclopropanecarboxylate oxidase (EC 1.14.17.4) from Arabidopsis thaliana (see paper)
28% identity, 92% coverage of query (208 bits)
ACO1 / P21399 cytoplasmic aconitate hydratase from Homo sapiens (see 6 papers)
ACOHC_HUMAN / P21399 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) (see 8 papers)
P21399 aconitate hydratase (EC 4.2.1.3) from Homo sapiens (see 3 papers)
28% identity, 92% coverage of query (208 bits)
2b3xA / P21399 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) (see paper)
28% identity, 92% coverage of query (208 bits)
D3GQL0 aconitate hydratase (EC 4.2.1.3) from Citrus clementina (see paper)
29% identity, 83% coverage of query (204 bits)
ACO3M_ARATH / Q9SIB9 Aconitate hydratase 3, mitochondrial; Aconitase 3; mACO1; Citrate hydro-lyase 3; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9SIB9 aconitate hydratase (EC 4.2.1.3) from Arabidopsis thaliana (see paper)
28% identity, 92% coverage of query (203 bits)
citB / P09339 aconitate hydratase (bifunctional aconitase) (EC 4.2.1.99; EC 4.2.1.3) from Bacillus subtilis (strain 168) (see 21 papers)
ACNA_BACSU / P09339 Aconitate hydratase A; ACN; Aconitase; Aconitate/2-methylaconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.- from Bacillus subtilis (strain 168) (see 7 papers)
P09339 aconitate hydratase (EC 4.2.1.3) from Bacillus subtilis (see paper)
28% identity, 93% coverage of query (198 bits)
D3GQL2 aconitate hydratase (EC 4.2.1.3) from Citrus clementina (see paper)
28% identity, 92% coverage of query (197 bits)
HP15_3433 Aconitate hydratase (EC 4.2.1.3) from Marinobacter adhaerens HP15
26% identity, 93% coverage of query (192 bits)
ACOHC_MOUSE / P28271 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Mus musculus (Mouse) (see paper)
P28271 aconitate hydratase (EC 4.2.1.3) from Mus musculus (see paper)
29% identity, 92% coverage of query (192 bits)
ACOHC_RABIT / Q01059 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Oryctolagus cuniculus (Rabbit) (see paper)
30% identity, 83% coverage of query (191 bits)
A0A090AMG4 aconitate hydratase (EC 4.2.1.3) from Achromobacter denitrificans (see paper)
29% identity, 93% coverage of query (191 bits)
ACOHC_BOVIN / Q0VCU1 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Bos taurus (Bovine) (see paper)
28% identity, 92% coverage of query (190 bits)
D3GQL1 aconitate hydratase (EC 4.2.1.3) from Citrus clementina (see paper)
27% identity, 92% coverage of query (190 bits)
ACNA_THET8 / Q5SMF6 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
28% identity, 81% coverage of query (187 bits)
ACOHC_RAT / Q63270 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Rattus norvegicus (Rat) (see paper)
Q63270 aconitate hydratase (EC 4.2.1.3) from Rattus norvegicus (see paper)
29% identity, 83% coverage of query (187 bits)
ACNA_BRADU / P70920 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) (see paper)
27% identity, 88% coverage of query (186 bits)
acnD / Q8EJW3 2-methylcitrate dehydratase (EC 4.2.1.117) from Shewanella oneidensis (strain MR-1) (see paper)
ACND_SHEON / Q8EJW3 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming); Aconitate hydratase; ACN; Aconitase; EC 4.2.1.117; EC 4.2.1.3 from Shewanella oneidensis (strain MR-1) (see paper)
Q8EJW3 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) (EC 4.2.1.117) from Shewanella oneidensis (see paper)
28% identity, 92% coverage of query (186 bits)
Q4JFF1 phosphinomethylmalate isomerase (EC 4.2.1.166) from Streptomyces viridochromogenes (see paper)
29% identity, 83% coverage of query (184 bits)
ACNA_CUPNE / Q937N8 Aconitate hydratase A; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha) (see paper)
27% identity, 92% coverage of query (184 bits)
acnA / Q8ZP52 aconitate hydratase 1 (EC 4.2.1.99) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
ACNA_SALTY / Q8ZP52 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
28% identity, 89% coverage of query (183 bits)
pmi / Q5IW57 phosphinomethylmalate isomerase (EC 4.2.1.166) from Streptomyces viridochromogenes (see paper)
28% identity, 83% coverage of query (183 bits)
3snpA / Q01059 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA (see paper)
29% identity, 83% coverage of query (181 bits)
A0QX20 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
26% identity, 85% coverage of query (160 bits)
O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
25% identity, 86% coverage of query (133 bits)
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Lawrence Berkeley National Laboratory