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Searching for up to 100 curated homologs for Echvi_2850 FitnessBrowser__Cola:Echvi_2850 (519 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 99

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AAQ89599.1 α-amylase (AmyM) (EC 3.2.1.1) (see protein)
    71% identity, 99% coverage of query (782 bits)

Q9ZAP8 neopullulanase (EC 3.2.1.135) from Paenibacillus polymyxa (see paper)
AAD05199.1 α-amylase (formerly neopullulanase) (EC 3.2.1.1) (see protein)
    43% identity, 97% coverage of query (414 bits)

AAL07400.1 α-amylase / neopullulanase (Npl) (EC 3.2.1.1) (see protein)
    43% identity, 92% coverage of query (405 bits)

AAN52525.1 α-amylase A (AmyA;Hore_14740) (EC 3.2.1.1) (see protein)
amyA / AAN52525.1 alpha-amylase A from Halothermothrix orenii (see paper)
    42% identity, 99% coverage of query (392 bits)

N515DRAFT_3391 Alpha-amylase (EC 3.2.1.1) from Dyella japonica UNC79MFTsu3.2
    43% identity, 93% coverage of query (392 bits)

ABU54057.1 α-amylase (BMW-amylase) (EC 3.2.1.1) (see protein)
    41% identity, 92% coverage of query (390 bits)

P20845 alpha-amylase (EC 3.2.1.1) from Priestia megaterium (see paper)
CAA30247.1 α-amylase (EC 3.2.1.1) (see protein)
    42% identity, 92% coverage of query (389 bits)

1wzaA / Q8GPL8 Crystal structure of alpha-amylase from h.Orenii (see paper)
    43% identity, 93% coverage of query (389 bits)

AAX84031.1 α-amylase (AmyF) (EC 3.2.1.1) (see protein)
    40% identity, 100% coverage of query (389 bits)

BAA07401.1 α-amylase (EC 3.2.1.1) (see protein)
    42% identity, 93% coverage of query (381 bits)

CAA34072.1 α-amylase 3 (AmyC) (EC 3.2.1.1) (see protein)
    38% identity, 99% coverage of query (370 bits)

A0A0U4VEK2 alpha-amylase (EC 3.2.1.1) from Paenibacillus sp. SSG-1 (see paper)
    41% identity, 92% coverage of query (364 bits)

AAW32491.1 α-amylase (AmyA) (EC 3.2.1.1) (see protein)
    39% identity, 93% coverage of query (348 bits)

BAH14969.1 g-cyclodextrin-specific cyclodextrinase (Cda) (EC 3.2.1.54) (see protein)
    37% identity, 93% coverage of query (311 bits)

CBK89424.1 maltogenic α-amylase (EUR_01860) (EC 3.2.1.133) (see protein)
    34% identity, 92% coverage of query (271 bits)

7jjnA Eubacterium rectale amy13b (eur_01860)
    34% identity, 92% coverage of query (267 bits)

A5ILB0 alpha-amylase (EC 3.2.1.1) from Thermotoga petrophila (see paper)
    35% identity, 84% coverage of query (261 bits)

CAA72194.1 α-amylase (AmyA;TM1840;Tmari_1848) (Amy13A) (EC 3.2.1.1) (see protein)
amyA / CAA72194.1 alpha-amylase from Thermotoga maritima (see paper)
    35% identity, 84% coverage of query (260 bits)

5m99A / A0A059TXD8 Functional characterization and crystal structure of thermostable amylase from thermotoga petrophila, reveals high thermostability and an archaic form of dimerization (see paper)
    35% identity, 84% coverage of query (258 bits)

MGTA_THENE / O86956 4-alpha-glucanotransferase; Amylomaltase; Disproportionating enzyme; D-enzyme; Maltodextrin glycosyltransferase; EC 2.4.1.25 from Thermotoga neapolitana
CAA08864.1 4-α-glucanotransferase (MgtA) (EC 2.4.1.25) (see protein)
    36% identity, 85% coverage of query (253 bits)

D1CE96 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermobaculum terrenum (see 4 papers)
    32% identity, 86% coverage of query (252 bits)

5x7uA / D1CE96 Trehalose synthase from thermobaculum terrenum (see paper)
    32% identity, 86% coverage of query (251 bits)

Build an alignment

Build an alignment for Echvi_2850 and 22 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

D1ABU6 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermomonospora curvata (see 2 papers)
    29% identity, 90% coverage of query (251 bits)

Q60035 4-alpha-glucanotransferase (EC 2.4.1.25) from Thermotoga maritima (see 2 papers)
CAA90693.1 4-α-glucanotransferase (Mgt;TM0364) (EC 2.4.1.25) (see protein)
1lwhA / P80099 Crystal structure of t. Maritima 4-alpha-glucanotransferase (see paper)
mgt / CAA90693.1 4-alpha-glucanotransferase from Thermotoga maritima (see paper)
    34% identity, 86% coverage of query (251 bits)

1lwjA Crystal structure of t. Maritima 4-alpha-glucanotransferase/acarbose complex
    34% identity, 86% coverage of query (251 bits)

Q47SE5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermobifida fusca (see paper)
    31% identity, 87% coverage of query (250 bits)

AAP49335.1 α-amylase (AmyA) (EC 3.2.1.1) (see protein)
    32% identity, 94% coverage of query (249 bits)

O16G_PARTM / P29094 Oligo-1,6-glucosidase; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase; EC 3.2.1.10 from Parageobacillus thermoglucosidasius (Geobacillus thermoglucosidasius) (see paper)
BAA01368.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    33% identity, 88% coverage of query (247 bits)

Q9RST7 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus radiodurans (see 2 papers)
    32% identity, 86% coverage of query (243 bits)

I3NX86 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus radiodurans (see 4 papers)
    32% identity, 86% coverage of query (243 bits)

5gtwA / I3NX86 The n253r mutant structures of trehalose synthase from deinococcus radiodurans display two different active-site conformations
    32% identity, 86% coverage of query (241 bits)

A0A2N0UQI0 alpha-amylase (EC 3.2.1.1) from Ruminococcus bromii (see paper)
    36% identity, 85% coverage of query (240 bits)

8ibkA / A0A2Z5WH92 Crystal structure of bacillus sp. Ahu2216 gh13_31 alpha-glucosidase e256q/n258g in complex with maltotriose (see paper)
    32% identity, 89% coverage of query (238 bits)

2ze0A / Q33E90 Alpha-glucosidase gsj (see paper)
    31% identity, 87% coverage of query (238 bits)

bsPTRE / BAE45038.1 trehalose-6-phosphate hydrolase from Geobacillus stearothermophilus (see paper)
    31% identity, 90% coverage of query (236 bits)

7jjtA / A0A2N0UXJ4 Ruminococcus bromii amylase amy5 (rbr_07800)
    36% identity, 85% coverage of query (236 bits)

M1PA89 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Rhodococcus opacus (see paper)
    29% identity, 85% coverage of query (234 bits)

S5YEW8 isomaltulose synthase (EC 5.4.99.11) from Pectobacterium carotovorum (see paper)
    31% identity, 88% coverage of query (234 bits)

A0A4S2BJW1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas stutzeri (see paper)
    30% identity, 88% coverage of query (233 bits)

5ykbD / I3NX86 The n253f mutant structure of trehalose synthase from deinococcus radiodurans reveals an open active-site conformation (see paper)
    31% identity, 86% coverage of query (232 bits)

Q65MI2 alpha,alpha-phosphotrehalase (EC 3.2.1.93) from Bacillus licheniformis (see 2 papers)
AAU39732.1 trehalose-6-P hydrolase (TreA;BlTreA;BLi00797;BL03069) (EC 3.2.1.93) (see protein)
    32% identity, 90% coverage of query (232 bits)

Q1J0Z5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus geothermalis (see paper)
    30% identity, 87% coverage of query (232 bits)

5do8B / Q8YAE6 1.8 angstrom crystal structure of listeria monocytogenes lmo0184 alpha-1,6-glucosidase (see paper)
    30% identity, 86% coverage of query (232 bits)

Q33E90 alpha-glucosidase (EC 3.2.1.20) from Geobacillus sp. HTA-462 (see paper)
BAE48285.1 α-glucosidase (Gsj) (EC 3.2.1.20) (see protein)
    30% identity, 87% coverage of query (231 bits)

4lxfB Crystal structure of m. Tuberculosis tres (see paper)
    30% identity, 90% coverage of query (230 bits)

C1DMP8 isomaltulose synthase (EC 5.4.99.11) from Azotobacter vinelandii (see paper)
    29% identity, 94% coverage of query (230 bits)

3zo9A The structure of trehalose synthase (tres) of mycobacterium smegmatis
    29% identity, 89% coverage of query (230 bits)

3zoaA The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose
    29% identity, 88% coverage of query (230 bits)

5brpA / Q65MI2 Crystal structure of bacillus licheniformis trehalose-6-phosphate hydrolase (trea), mutant r201q, in complex with png (see paper)
    32% identity, 90% coverage of query (229 bits)

Q6L2Z7 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Picrophilus torridus (see 2 papers)
    29% identity, 88% coverage of query (229 bits)

Q88FN0 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas putida (see 2 papers)
    31% identity, 83% coverage of query (229 bits)

CAA37583.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    30% identity, 88% coverage of query (228 bits)

5jy7B / A0R6E0 Complex of mycobacterium smegmatis trehalose synthase with maltokinase (see paper)
    29% identity, 85% coverage of query (227 bits)

3zoaB The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose
    29% identity, 85% coverage of query (227 bits)

treS / A0R6E0 trehalose synthase subunit (EC 5.4.99.16) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (see 4 papers)
TRES_MYCS2 / A0R6E0 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 6 papers)
A0R6E0 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Mycolicibacterium smegmatis (see 3 papers)
    29% identity, 85% coverage of query (226 bits)

I3WCP4 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas sp. P8005 (see paper)
    30% identity, 84% coverage of query (226 bits)

BAA12704.1 α-glucosidase / exo-α-1,4-glucosidase (EC 3.2.1.20) (see protein)
    29% identity, 87% coverage of query (225 bits)

AAF71997.1 α-glucosidase (EC 3.2.1.20) (see protein)
    31% identity, 93% coverage of query (225 bits)

BAG86620.1 trehalose-6-phosphate hydrolase (TreC;KP1_0530) (EC 3.2.1.93) (see protein)
    33% identity, 86% coverage of query (225 bits)

CAA54266.1 α-glucosidase (EC 3.2.1.20) (see protein)
CAA54266.1 alpha-glucosidase from Bacillus sp. (see paper)
    31% identity, 91% coverage of query (224 bits)

7lv6B / O06994 The structure of mall mutant enzyme s536r from bacillus subtilis
    31% identity, 88% coverage of query (224 bits)

O16G1_BACSU / O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see 3 papers)
CAB15461.1 α-1,6-glucosidase (MalL;YvdL;BSU34560) (EC 3.2.1.10) (see protein)
    31% identity, 88% coverage of query (224 bits)

AAK28739.1 α-glucosidase (PalZ) (EC 3.2.1.20) (see protein)
    29% identity, 88% coverage of query (224 bits)

4mazA The structure of mall mutant enzyme v200s from bacillus subtilus
    31% identity, 88% coverage of query (224 bits)

5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin
    31% identity, 88% coverage of query (224 bits)

4m56A The structure of wild-type mall from bacillus subtilis
    31% identity, 88% coverage of query (224 bits)

TRES_MYCTU / P9WQ19 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WQ19 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Mycobacterium tuberculosis (see paper)
    29% identity, 88% coverage of query (223 bits)

CAA02858.1 palatinase / trehalulose hydrolase (MutA) (EC 3.2.1.10|3.2.1.-) (see protein)
    31% identity, 89% coverage of query (223 bits)

A0A2Z4RCL2 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas putida (see paper)
    30% identity, 83% coverage of query (223 bits)

AAP10934.1 oligo-α-1,6-glucosidase (BC4015) (EC 3.2.1.10) (see protein)
    29% identity, 88% coverage of query (223 bits)

4lxfA Crystal structure of m. Tuberculosis tres (see paper)
    28% identity, 90% coverage of query (221 bits)

A8QX00 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Actinoplanes sp. (see paper)
    28% identity, 91% coverage of query (221 bits)

O16G2_BACSU / O34364 Probable oligo-1,6-glucosidase 2; Oligosaccharide alpha-1,6-glucosidase 2; Sucrase-isomaltase 2; Isomaltase 2; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see paper)
    30% identity, 92% coverage of query (219 bits)

Q9F4G4 oligo-1,6-glucosidase (EC 3.2.1.10) from Bacillus subtilis (see paper)
AAG23399.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    31% identity, 88% coverage of query (219 bits)

ACE77085.1 oligosaccharide-producing multifunctional amylase (OPMA) (EC 2.4.1.-) (see protein)
    31% identity, 88% coverage of query (219 bits)

Q5FMB7 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Lactobacillus acidophilus (see paper)
AAV42157.1 oligo-α-1,6-glucosidase (LBA0264) (EC 3.2.1.10) (see protein)
    31% identity, 86% coverage of query (218 bits)

4aieA / Q5FMB7 Structure of glucan-1,6-alpha-glucosidase from lactobacillus acidophilus ncfm (see paper)
    31% identity, 86% coverage of query (218 bits)

AAS80455.1 α,α-trehalase / α-glucosidase (TTC0107) (EC 3.2.1.20|3.2.1.28) (see protein)
    32% identity, 88% coverage of query (218 bits)

A0A223KY92 alpha-amylase (EC 3.2.1.1) from Sutcliffiella cohnii (see paper)
    30% identity, 86% coverage of query (217 bits)

PGA1_c07890 cytoplasmic trehalase (AlgA) from Phaeobacter inhibens BS107
    29% identity, 92% coverage of query (217 bits)

treA / P39795 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Bacillus subtilis (strain 168) (see paper)
TREC_BACSU / P39795 Trehalose-6-phosphate hydrolase; Alpha,alpha-phosphotrehalase; Phospho-alpha-(1-1)-glucosidase; EC 3.2.1.93 from Bacillus subtilis (strain 168) (see 2 papers)
CAB12610.1 trehalose-6-phosphate hydrolase (TreA;BSU07810) (EC 3.2.1.93) (see protein)
    30% identity, 87% coverage of query (217 bits)

Q8KR84 isomaltulose synthase (EC 5.4.99.11) from Klebsiella sp. LX3 (see paper)
    30% identity, 92% coverage of query (217 bits)

palI / Q9AI64 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see 2 papers)
Q9AI64 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see paper)
    29% identity, 93% coverage of query (216 bits)

Q6XNK5 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see paper)
    29% identity, 93% coverage of query (216 bits)

D9MPF2 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see 3 papers)
    29% identity, 93% coverage of query (216 bits)

AAD50603.1 α-glucosidase (EC 3.2.1.20) (see protein)
    31% identity, 88% coverage of query (216 bits)

BAB18518.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    31% identity, 88% coverage of query (216 bits)

4howA / D9MPF2 The crystal structure of isomaltulose synthase from erwinia rhapontici nx5 (see paper)
    30% identity, 87% coverage of query (214 bits)

B1PK99 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Meiothermus ruber (see 4 papers)
    31% identity, 88% coverage of query (214 bits)

Q5SL15 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see paper)
    32% identity, 87% coverage of query (214 bits)

AAF69018.1 α-glucosidase (MAL1) (EC 3.2.1.20) (see protein)
    31% identity, 89% coverage of query (214 bits)

Q5SL12 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB8 (see paper)
BAD70304.1 α-glucosidase (TTHA0481) (EC 3.2.1.20) (see protein)
    31% identity, 88% coverage of query (214 bits)

BAA11354.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    30% identity, 87% coverage of query (214 bits)

Q7WUI5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see 2 papers)
    32% identity, 87% coverage of query (213 bits)

B8YM30 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Paenarthrobacter aurescens (see 2 papers)
    28% identity, 84% coverage of query (213 bits)

CAA55409.1 α-1,4-glucosidase (MalA) (EC 3.2.1.20) (see protein)
    28% identity, 87% coverage of query (213 bits)

AGT54942.1 α-amylase (Amy703;Amy) (EC 3.2.1.1) (see protein)
    29% identity, 94% coverage of query (213 bits)

Dshi_1649 alpha-glucosidase / maltase / trehalase / sucrase (EC 3.2.1.48; EC 3.2.1.20; EC 3.2.1.28) from Dinoroseobacter shibae DFL-12
    28% identity, 88% coverage of query (213 bits)

4hphA The crystal structure of isomaltulose synthase mutant e295q from erwinia rhapontici nx5 in complex with its natural substrate sucrose
    29% identity, 87% coverage of query (213 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory