Searching for up to 100 curated homologs for Echvi_3063 FitnessBrowser__Cola:Echvi_3063 (253 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YnhD / b1682 Fe-S cluster scaffold complex subunit SufC from Escherichia coli K-12 substr. MG1655 (see 25 papers)
SUFC_ECOLI / P77499 Probable ATP-dependent transporter SufC from Escherichia coli (strain K12) (see 3 papers)
66% identity, 96% coverage of query (343 bits)
2d2fA / Q5SH92 Crystal structure of atypical cytoplasmic abc-atpase sufc from thermus thermophilus hb8 (see paper)
55% identity, 98% coverage of query (287 bits)
Y273_STRP6 / Q5XDV5 Probable ABC transporter ATP-binding protein M6_Spy0273 from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
53% identity, 98% coverage of query (273 bits)
AB6I_ARATH / Q9CAF5 ABC transporter I family member 6, chloroplastic; ABC transporter ABCI.6; AtABCI6; ABC transporter ATPase; Non-intrinsic ABC protein 7; AtNAP7; Plastid SufC-like protein from Arabidopsis thaliana (Mouse-ear cress) (see paper)
50% identity, 96% coverage of query (253 bits)
SUFC_PLAF7 / Q8ILW0 Iron-sulfur cluster assembly protein SufC; PfSufC; EC 3.6.1.- from Plasmodium falciparum (isolate 3D7) (see 4 papers)
49% identity, 95% coverage of query (240 bits)
SUFC_PLABA / A0A509AN56 Iron-sulfur cluster assembly protein SufC; EC 3.6.1.- from Plasmodium berghei (strain Anka) (see paper)
47% identity, 95% coverage of query (232 bits)
7qkrA / F2QQK6 Cryo-em structure of abc transporter ste6-2p from pichia pastoris with verapamil at 3.2 a resolution (see paper)
32% identity, 91% coverage of query (88.2 bits)
MDR2_TRIRC / F2T1C4 ABC multidrug transporter MDR2; Multidrug resistance protein 2 from Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot fungus) (see 3 papers)
30% identity, 85% coverage of query (84.3 bits)
MDR2_TRIIM / A0A059JJ46 ABC multidrug transporter MDR2; Multidrug resistance protein 2 from Trichophyton interdigitale (strain MR816) (see 4 papers)
30% identity, 85% coverage of query (84.0 bits)
TC 3.A.1.5.8 / Q97UG5 MalK, component of Maltose and maltooligosaccharide porter from Sulfolobus solfataricus (see paper)
30% identity, 89% coverage of query (83.6 bits)
MDR2_TRIEC / F2PRR1 ABC multidrug transporter MDR2; Multidrug resistance protein 2 from Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97) (Horse ringworm fungus) (see paper)
MDR2_TRIT1 / F2RP52 ABC multidrug transporter MDR2; Multidrug resistance protein 2 from Trichophyton tonsurans (strain CBS 112818) (Scalp ringworm fungus) (see paper)
30% identity, 85% coverage of query (83.2 bits)
Build an alignment for Echvi_3063 and 11 homologs with ≥ 30% identity
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3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
29% identity, 93% coverage of query (83.2 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
29% identity, 93% coverage of query (83.2 bits)
2olkA Abc protein artp in complex with adp-beta-s
29% identity, 93% coverage of query (83.2 bits)
2oljA Abc protein artp in complex with adp/mg2+
29% identity, 93% coverage of query (83.2 bits)
TC 3.A.1.1.49 / O30494 MtlK, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
30% identity, 90% coverage of query (82.8 bits)
MDR2_ASPFU / Q4WPP6 ABC multidrug transporter mdr2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 4 papers)
32% identity, 86% coverage of query (82.4 bits)
PS417_12700 ABC transporter for D-Mannitol and D-Sorbitol, ATPase component from Pseudomonas simiae WCS417
30% identity, 90% coverage of query (82.0 bits)
IRTA_MYCS2 / A0R6H8 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
30% identity, 87% coverage of query (81.6 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
29% identity, 91% coverage of query (81.3 bits)
IRTA_MYCTU / P9WQJ9 Mycobactin import ATP-binding/permease protein IrtA; Iron-regulated transporter A; EC 7.2.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
TC 3.A.1.21.2 / P63391 IrtA, component of The Fe3+-carboxymycobactin transporter, IrtAB (Rodriguez and Smith, 2006). IrtA contains an FAD-binding domain (see 2 papers)
28% identity, 87% coverage of query (80.5 bits)
MDR1_ASPFU / Q4WTT9 ABC multidrug transporter mdr1 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 5 papers)
32% identity, 85% coverage of query (80.5 bits)
TC 3.A.1.201.10 / B0Y3B6 Mdr1; resistance to Cilofungin and other drugs from Aspergillus fumigatus (strain CEA10 / CBS 144.89 / FGSC A1163) (see paper)
32% identity, 85% coverage of query (80.5 bits)
AO356_00010 ABC transporter for D-Sorbitol, ATPase component from Pseudomonas fluorescens FW300-N2C3
30% identity, 90% coverage of query (80.5 bits)
MDR_STABO / H6TB12 Sophorolipid transporter; EC 7.6.2.- from Starmerella bombicola (Yeast) (Candida bombicola) (see 2 papers)
30% identity, 90% coverage of query (80.1 bits)
Pf6N2E2_1960 ABC transporter for D-sorbitol, ATPase component from Pseudomonas fluorescens FW300-N2E2
30% identity, 90% coverage of query (80.1 bits)
PGA1_c12640 D-lactate transporter, ATP-binding component from Phaeobacter inhibens BS107
30% identity, 88% coverage of query (80.1 bits)
ABC1_MYCTU / O65934 ABC transporter ATP-binding/permease protein Rv1747; EC 7.-.-.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
31% identity, 87% coverage of query (80.1 bits)
ATRD_EMENI / Q5BAY0 ABC multidrug transporter atrD from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
31% identity, 85% coverage of query (80.1 bits)
ATRD_EMEND / Q9Y8G1 ABC multidrug transporter atrD from Emericella nidulans (Aspergillus nidulans) (see 2 papers)
atrD ABC-transporter from Emericella nidulans (see paper)
31% identity, 85% coverage of query (79.7 bits)
TR06_CURCL / A0A348AXX9 ABC-type transporter TR06; KK-1 biosynthesis cluster protein 6 from Curvularia clavata (see paper)
29% identity, 91% coverage of query (79.7 bits)
1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter
28% identity, 85% coverage of query (79.3 bits)
MDR4_ASPFU / Q4WSI1 ABC multidrug transporter mdr4 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 6 papers)
29% identity, 86% coverage of query (79.0 bits)
TC 3.A.1.1.4 / Q01937 LacK, component of Lactose porter from Agrobacterium radiobacter (see paper)
29% identity, 92% coverage of query (78.6 bits)
TC 3.A.1.135.1 / Q9CIP6 YdaG; aka ABC transporter ATP binding and permease protein, component of The heterodimeric multidrug exporter, YdaG/YbdA (Both proteins are ABC half transporters; only the heterodimer is active; ethidium, daunomycin and BCECF-AM are substrates; Lubelski et al., 2004) These proteins have been renamed LmrC and LmrD from Lactococcus lactis (subsp. lactis) (Streptococcus lactis) (see paper)
28% identity, 86% coverage of query (78.6 bits)
MDR5_TRIRC / F2SQT8 ABC multidrug transporter MDR5; Multidrug resistance protein 5 from Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot fungus) (see paper)
29% identity, 92% coverage of query (78.2 bits)
mtlK / Q4KC54 polyol ABC-type transporterATP-binding component MtlK from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
28% identity, 90% coverage of query (78.2 bits)
7wivA / P9WQJ9 Cryo-em structure of mycobacterium tuberculosis irtab in complex with an amp-pnp
28% identity, 87% coverage of query (78.2 bits)
PGA1_c27970 N-Acetyl-D-glucosamine ABC transport system, ATPase component from Phaeobacter inhibens BS107
27% identity, 99% coverage of query (78.2 bits)
TC 3.A.1.135.8 / Q837P5 ABC transporter, ATP-binding/permease protein, component of Multidrug efflux pump, EfrCD from Enterococcus faecalis (strain ATCC 700802 / V583)
31% identity, 85% coverage of query (78.2 bits)
7wixA Cryo-em structure of mycobacterium tuberculosis irtab in complex with adp
28% identity, 87% coverage of query (78.2 bits)
1g6hA / Q58663 Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
28% identity, 85% coverage of query (77.4 bits)
7wiwA Cryo-em structure of mycobacterium tuberculosis irtab complexed with atp in an occluded conformation
27% identity, 87% coverage of query (77.0 bits)
MDL1_YEAST / P33310 ATP-dependent permease MDL1, mitochondrial; ABC transporter MDL1; Multidrug resistance-like protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
TC 3.A.1.212.1 / P33310 The mitochondrial peptide exporter, Mdl1p (exports peptides of 6-21 amino acyl residues from the mitochondrial matrix as well as degradation products of misassembled respiratory chain complexes) (Janas et al., 2003; van der Does et al., 2006; Gompf et al., 2007). A leaderless Mdl1p targets to the ER membrane instead of to the mitochondria from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
MDL1 / RF|NP_013289.1 ATP-dependent permease MDL1, mitochondrial; EC 3.6.3.43 from Saccharomyces cerevisiae (see paper)
31% identity, 85% coverage of query (75.9 bits)
ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
27% identity, 94% coverage of query (75.5 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
29% identity, 91% coverage of query (75.1 bits)
IRTA_MYCT3 / G7CBF5 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
26% identity, 87% coverage of query (75.1 bits)
4f4cA / P34712 The crystal structure of the multi-drug transporter (see paper)
25% identity, 85% coverage of query (73.9 bits)
5l22B / O67184 Prtd t1ss abc transporter (see paper)
29% identity, 88% coverage of query (73.9 bits)
4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
28% identity, 88% coverage of query (72.0 bits)
6tejB / A0A100XE85 Structure of apo irtab devoid sid in complex with sybody syb_nl5 (see paper)
29% identity, 85% coverage of query (72.0 bits)
2onjA Structure of the multidrug abc transporter sav1866 from s. Aureus in complex with amp-pnp
31% identity, 85% coverage of query (72.0 bits)
Y1866_STAAM / Q99T13 Putative multidrug export ATP-binding/permease protein SAV1866; EC 7.6.2.- from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
Q99T13 ABC-type xenobiotic transporter (EC 7.6.2.2) from Staphylococcus aureus (see paper)
TC 3.A.1.106.2 / Q2G2M9 The homodimeric Sav1866 multidrug exporter (transports doxorubicin, verapamil, ethidium, tetraphenylphosphonium, vinblastine and the fluorescent dye, Hoechst 33342; 3-D structure known at 3 Å resolution; Dawson and Locher, 2006; Velamakanni et al., 2008) The empty site opens by rotation of the nucleotide-binding domain whereas the ATP-bound site remains occluded (Jones and George, 2011). Conformational changes induced by ATP-binding and hydrolysis have been proposed (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent from Staphylococcus aureus (strain NCTC 8325)
2hydA / Q99T13 Multidrug abc transporter sav1866 (see paper)
31% identity, 85% coverage of query (72.0 bits)
5ochC / Q9NUT2 The crystal structure of human abcb8 in an outward-facing state
27% identity, 87% coverage of query (71.2 bits)
5ochE / Q9NUT2 The crystal structure of human abcb8 in an outward-facing state
27% identity, 87% coverage of query (71.2 bits)
2pmkA Crystal structures of an isolated abc-atpase in complex with tnp-adp
27% identity, 91% coverage of query (71.2 bits)
2ff7A The abc-atpase of the abc-transporter hlyb in the adp bound state
27% identity, 91% coverage of query (71.2 bits)
MITOS_HUMAN / Q9NUT2 Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial ATP-binding cassette 1; M-ABC1; Mitochondrial sulfonylurea-receptor; MITOSUR from Homo sapiens (Human) (see 5 papers)
Q9NUT2 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
TC 3.A.1.201.22 / Q9NUT2 Mitochondrial ATP-binding cassette 1, ABCB8 from Homo sapiens
27% identity, 87% coverage of query (70.9 bits)
4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
28% identity, 88% coverage of query (70.5 bits)
3b5jA Crystal structures of the s504a mutant of an isolated abc-atpase in complex with tnp-adp
27% identity, 91% coverage of query (70.1 bits)
4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
27% identity, 91% coverage of query (70.1 bits)
ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
28% identity, 91% coverage of query (70.1 bits)
8i3cA Cryo-em structure of abscisic acid transporter atabcg25 with chs
27% identity, 89% coverage of query (69.7 bits)
5eg1B / Q9X2W0 Antibacterial peptide abc transporter mcjd with a resolved lipid (see paper)
30% identity, 90% coverage of query (69.7 bits)
5ofrA Structure of the antibacterial peptide abc transporter mcjd in a high energy outward occluded intermediate state
30% identity, 90% coverage of query (69.7 bits)
7ehlA Cryo-em structure of human abcb8 transporter in nucleotide binding state
28% identity, 87% coverage of query (69.7 bits)
8i39A Cryo-em structure of abscisic acid transporter atabcg25 with aba
27% identity, 89% coverage of query (69.3 bits)
7sgrE / Q8FDZ8 Structure of hemolysin a secretion system hlyb/d complex (see paper)
28% identity, 91% coverage of query (69.3 bits)
8i3aA / Q84TH5 Cryo-em structure of abscisic acid transporter atabcg25 in outward conformation (see paper)
27% identity, 89% coverage of query (68.6 bits)
6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
29% identity, 91% coverage of query (68.6 bits)
3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
29% identity, 91% coverage of query (68.6 bits)
3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
29% identity, 91% coverage of query (68.6 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
26% identity, 100% coverage of query (68.6 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
26% identity, 100% coverage of query (68.6 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
26% identity, 100% coverage of query (68.6 bits)
4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
29% identity, 91% coverage of query (68.6 bits)
7otgA Structure of abcb1/p-glycoprotein in the presence of the cftr potentiator ivacaftor
29% identity, 91% coverage of query (68.6 bits)
4q9iA P-glycoprotein cocrystallised with qz-ala
29% identity, 91% coverage of query (68.6 bits)
8dckA Structure of hemolysin a secretion system hlyb/d complex, atp-bound
27% identity, 91% coverage of query (68.2 bits)
4xwkA P-glycoprotein co-crystallized with bde-100
29% identity, 91% coverage of query (68.2 bits)
3wmgA Crystal structure of an inward-facing eukaryotic abc multidrug transporter g277v/a278v/a279v mutant in complex with an cyclic peptide inhibitor, acap
29% identity, 89% coverage of query (68.2 bits)
6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
26% identity, 86% coverage of query (67.8 bits)
7zk6A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to 2 molecules of aac
29% identity, 91% coverage of query (67.8 bits)
7zk5A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to aac
29% identity, 91% coverage of query (67.8 bits)
6a6mA / M1VAN7 Crystal structure of an outward-open nucleotide-bound state of the eukaryotic abc multidrug transporter cmabcb1 (see paper)
29% identity, 89% coverage of query (67.8 bits)
7zkaA Abcb1 v978c mutant (mabcb1) in the outward facing state bound to aac
29% identity, 91% coverage of query (67.8 bits)
7fc9A Crystal structure of cmabcb1 in lipidic mesophase revealed by lcp-sfx
29% identity, 89% coverage of query (67.8 bits)
7zk4A The abcb1 l335c mutant (mabcb1) in the outward facing state
29% identity, 91% coverage of query (67.8 bits)
6qeeA Nanodisc reconstituted human-mouse chimeric abcb1 (abcb1hm)-eq mutant in complex with uic2 fab and zosuquidar.
29% identity, 91% coverage of query (67.4 bits)
5koyA Mouse pgp 34 linker deleted bound with atp
29% identity, 91% coverage of query (67.4 bits)
ABCG5_MOUSE / Q99PE8 ATP-binding cassette sub-family G member 5; Sterolin-1; EC 7.6.2.- from Mus musculus (Mouse) (see 15 papers)
27% identity, 89% coverage of query (67.4 bits)
TAP2_RAT / P36372 Antigen peptide transporter 2; APT2; ATP-binding cassette sub-family B member 3; EC 7.4.2.14 from Rattus norvegicus (Rat) (see paper)
P36372 ABC-type antigen peptide transporter (subunit 1/2) (EC 7.4.2.14) from Rattus norvegicus (see 6 papers)
30% identity, 84% coverage of query (67.0 bits)
1xefA Crystal structure of the atp/mg2+ bound composite dimer of hlyb-nbd
27% identity, 91% coverage of query (67.0 bits)
6bppA E. Coli msba in complex with lps and inhibitor g092
27% identity, 85% coverage of query (67.0 bits)
6bplA E. Coli msba in complex with lps and inhibitor g907
27% identity, 85% coverage of query (67.0 bits)
7mewA E. Coli msba in complex with g247
27% identity, 85% coverage of query (67.0 bits)
7bcwA Structure of msba in salipro with adp vanadate
27% identity, 85% coverage of query (67.0 bits)
7ph3A / P60752 Amp-pnp bound nanodisc reconstituted msba with nanobodies, spin- labeled at position a60c (see paper)
27% identity, 85% coverage of query (67.0 bits)
AB27B_ARATH / Q0WML0 ABC transporter B family member 27; ABC transporter ABCB.27; AtABCB27; Aluminum tolerance-related ATP-binding cassette transporter; Antigen peptide transporter-like 2; Transporter associated with antigen processing-like protein 2; AtTAP2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 3.A.1.201.8 / Q0WML0 The aluminum chelate (aluminum sensitivity (ALS1)) protein; expressed in root vacuoles half-type ABC transporter from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
TAP2 / RF|NP_198720.2 antigen peptide transporter-like 2 from Arabidopsis thaliana (see paper)
24% identity, 94% coverage of query (67.0 bits)
MsbA / b0914 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli K-12 substr. MG1655 (see 54 papers)
msbA / P60752 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli (strain K12) (see 57 papers)
MSBA_ECOLI / P60752 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; Lipid flippase; EC 7.5.2.6 from Escherichia coli (strain K12) (see 17 papers)
P60752 ABC-type lipid A-core oligosaccharide transporter (EC 7.5.2.6); P-type phospholipid transporter (EC 7.6.2.1) from Escherichia coli (see 13 papers)
TC 3.A.1.106.1 / P60752 Phospholipid, LPS, lipid A and drug exporter, MsbA, which flips the substrate from the inner leaflet of the cytoplasmic membrane to the outer leaflet (Eckford and Sharom, 2010). MsbA also confers drug resistance to azidopine, daunomycin, vinblastine, Hoechst 33342 and ethidium (Reuter et al., 2003). Four x-ray structures, trapped in different conformations, two with and two without nucleotide, have been solved (Ward et al., 2007). They suggest an alternating accessibility mode of transport with major conformational changes from Escherichia coli (see 11 papers)
msbA / MB|P60752 lipid A export ATP-binding/permease protein msbA; EC 3.6.3.- from Escherichia coli K12 (see 24 papers)
27% identity, 85% coverage of query (67.0 bits)
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