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Searching for up to 100 curated homologs for Echvi_3112 FitnessBrowser__Cola:Echvi_3112 (271 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.14.18 / Q32AY3 Hemin import ATP-binding protein hmuV, component of The heme uptake porter, ShuTUV (Burkhard and Wilks, 2008). Transports a single heme per reaction cycle (Mattle et al., 2010). (3-d structure of ShuT is known (2RG7) from Shigella dysenteriae serotype 1 (strain Sd197) (see paper)
    42% identity, 93% coverage of query (209 bits)

TC 3.A.1.14.5 / Q56993 HmuV aka YPO0279 aka Y0539, component of Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle from Yersinia pestis (see 4 papers)
hmuV hemin import ATP-binding protein hmuV; EC 3.6.3.- from Yersinia pestis KIM (see paper)
    42% identity, 90% coverage of query (202 bits)

TC 3.A.1.14.16 / A8GDS6 HemV, component of The heme-specific uptake porter, HemTUV from Serratia proteamaculans (strain 568)
    42% identity, 90% coverage of query (194 bits)

TC 3.A.1.14.21 / O68877 Hemin import ATP-binding protein HmuV, component of The heme uptake porter, PhuTUV (transports one heme per reaction cycle) from Pseudomonas aeruginosa (see 2 papers)
    39% identity, 90% coverage of query (168 bits)

TC 3.A.1.14.19 / Q93SS1 Hemin import ATP-binding protein hmuV, component of Heme uptake porter, HugBCD (Villarreal et al., 2008); also called HmuTUV from Plesiomonas shigelloides (see paper)
    36% identity, 86% coverage of query (160 bits)

hmuV / CAC34395.1 HmuV protein from Rhizobium leguminosarum (see paper)
    35% identity, 96% coverage of query (160 bits)

TC 3.A.1.14.20 / Q7W025 Hemin import ATP-binding protein HmuV, component of Heme-iron (hemin) utilization transporter BhuTUV from Bordetella pertussis (see paper)
    37% identity, 91% coverage of query (152 bits)

FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
    34% identity, 91% coverage of query (141 bits)

TC 3.A.1.14.7 / Q9X665 FhuC aka FhuA, component of Iron (Fe3+)-hydroxamate porter (transports Fe3+-ferrichrome and Fe3+-ferrioxamine B with FhuD1, and these compounds plus aerobactin and coprogen with FhuD2) (see 2 papers)
    33% identity, 88% coverage of query (138 bits)

fhuC / GI|2832798 ferrichrome transport ATP-binding protein FhuC from Bacillus subtilis (see paper)
    32% identity, 96% coverage of query (137 bits)

FPUC_BACAN / Q81LM1 Petrobactin import ATP-binding protein FpuC; EC 7.2.2.- from Bacillus anthracis (see paper)
    30% identity, 89% coverage of query (132 bits)

Build an alignment

Build an alignment for Echvi_3112 and 11 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

FATE_BACAN / Q81XB3 Petrobactin import ATP-binding protein FatE; EC 7.2.2.- from Bacillus anthracis (see paper)
    29% identity, 90% coverage of query (129 bits)

TC 3.A.1.14.14 / Q9A197 Putative ferrichrome ABC transporter aka SiuA aka Spy0386, component of The Fe3+ /Fe3+ferrichrome/Fe3+heme uptake porter; SiuABDG (FTSABCD) from Streptococcus pyogenes serotype M1 (see 2 papers)
    32% identity, 94% coverage of query (128 bits)

BTUDA_HALSA / Q9HQ18 Cobalamin import ATP-binding protein BtuD; Vitamin B12-transporting ATPase; EC 7.6.2.8 from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) (see paper)
    35% identity, 85% coverage of query (126 bits)

FepC / b0588 ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
FepC / P23878 ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) from Escherichia coli (strain K12) (see 3 papers)
FEPC_ECOLI / P23878 Ferric enterobactin transport ATP-binding protein FepC; EC 7.2.2.17 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.2 / P23878 FepC aka B0588, component of Iron (Fe3+)-enterobactin porter from Escherichia coli (see 3 papers)
    29% identity, 96% coverage of query (123 bits)

TC 3.A.1.14.6 / Q9RCF3 ViuC, component of The iron-vibriobactin/enterobactin uptake porter from Vibrio cholerae (see 2 papers)
    31% identity, 93% coverage of query (122 bits)

FecE / b4287 ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
FecE / P15031 ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) from Escherichia coli (strain K12) (see 2 papers)
FECE_ECOLI / P15031 Fe(3+) dicitrate transport ATP-binding protein FecE; Iron(III) dicitrate transport ATP-binding protein FecE; EC 7.2.2.18 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.1 / P15031 Fe(3+) dicitrate transport ATP-binding protein FecE, component of Iron (Fe3+) or ferric-dicitrate porter from Escherichia coli (strain K12) (see 4 papers)
fecE / GB|AAC77243.1 iron(III) dicitrate transport ATP-binding protein FecE from Escherichia coli K12 (see 6 papers)
    32% identity, 91% coverage of query (122 bits)

TC 3.A.1.15.8 / P96117 TroB, component of Manganese (Mn2+), zinc (Zn2+) and possibly iron (Fe2+) uptake porter, TroABCD from Treponema pallidum (see 2 papers)
    31% identity, 93% coverage of query (121 bits)

TC 3.A.1.14.13 / Q9RK11 CchE, component of Ferric iron-coelichelin uptake porter, CchCDEF from Streptomyces coelicolor (see paper)
    33% identity, 93% coverage of query (120 bits)

TC 3.A.1.14.12 / Q9L177 DesC, component of Desferrioxamine B uptake porter, DesABC from Streptomyces coelicolor (see paper)
    31% identity, 90% coverage of query (120 bits)

MNTB_BACSU / O34338 Manganese transport system ATP-binding protein MntB from Bacillus subtilis (strain 168) (see paper)
    31% identity, 89% coverage of query (118 bits)

1l7vC Bacterial abc transporter involved in b12 uptake
    34% identity, 79% coverage of query (113 bits)

4fi3C / P06611 Structure of vitamin b12 transporter btucd-f in a nucleotide-bound state (see paper)
    33% identity, 79% coverage of query (112 bits)

PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
    31% identity, 87% coverage of query (102 bits)

5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
    33% identity, 78% coverage of query (99.4 bits)

4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
    27% identity, 85% coverage of query (93.2 bits)

7wixB / P9WQJ7 Cryo-em structure of mycobacterium tuberculosis irtab in complex with adp
    32% identity, 79% coverage of query (92.8 bits)

6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
    26% identity, 87% coverage of query (92.4 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    32% identity, 74% coverage of query (91.3 bits)

7wiwB Cryo-em structure of mycobacterium tuberculosis irtab complexed with atp in an occluded conformation
    32% identity, 79% coverage of query (91.3 bits)

AB25B_ARATH / Q9LVM1 ABC transporter B family member 25, mitochondrial; ABC transporter ABCB.25; AtABCB25; ABC transporter of the mitochondrion 3; AtATM3; Iron-sulfur clusters transporter ATM3; Protein STARIK 1 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.210.8 / Q9LVM1 Mitochondrial ABC transporter, ATM3, involved in iron homeostasis (Chen et al. 2007) and heavy metal resistance (Kim et al. 2006). There are three isoforms: ATM1, ATM2 and ATM3 (Chen et al., 2007). ATM3 can replace the yeast iron/sulfur cluster exporter better than ATM1 or ATM2. Atm3 is most similar to the human and yeast homologues, TC# 3.A.1.210.4 and 3.A.1.210.1, 51% and 47% identical, respectively from Arabidopsis thaliana (Mouse-ear cress) (see 11 papers)
GB|AAN13224.1 putative ABC transporter protein from Arabidopsis thaliana (see paper)
    32% identity, 81% coverage of query (91.3 bits)

7n59A / Q9LVM1 Structure of atatm3 in the inward-facing conformation with gssg bound (see paper)
    32% identity, 81% coverage of query (91.3 bits)

7n5aA Structure of atatm3 in the closed conformation
    32% identity, 81% coverage of query (90.9 bits)

8iddA Cryo-em structure of mycobacterium tuberculosis atp bound ftsex/ripc complex in peptidisc
    28% identity, 80% coverage of query (90.5 bits)

8igqA / O05779 Cryo-em structure of mycobacterium tuberculosis adp bound ftsex/ripc complex in peptidisc (see paper)
    28% identity, 80% coverage of query (90.5 bits)

8g4cB / O34697 Bceabs atpgs high res tm (see paper)
    31% identity, 76% coverage of query (89.7 bits)

6tejB / A0A100XE85 Structure of apo irtab devoid sid in complex with sybody syb_nl5 (see paper)
    31% identity, 84% coverage of query (89.7 bits)

FTSE_MYCTA / A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
    28% identity, 75% coverage of query (88.6 bits)

7tchB Bceab e169q variant atp-bound conformation
    31% identity, 76% coverage of query (88.6 bits)

3nhaA Nucleotide binding domain of human abcb6 (adp mg bound structure)
    30% identity, 83% coverage of query (88.2 bits)

4q4aA / Q9WYC3 Improved model of amp-pnp bound tm287/288 (see paper)
    28% identity, 81% coverage of query (88.2 bits)

5l22B / O67184 Prtd t1ss abc transporter (see paper)
    30% identity, 79% coverage of query (88.2 bits)

6quzA Structure of atpgs-bound outward-facing tm287/288 in complex with sybody sb_tm35
    28% identity, 81% coverage of query (88.2 bits)

6qv0A Structure of atp-bound outward-facing tm287/288 in complex with sybody sb_tm35
    28% identity, 81% coverage of query (88.2 bits)

4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
    32% identity, 80% coverage of query (88.2 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    33% identity, 77% coverage of query (87.8 bits)

7y48B Cryo-em structure of biliverdin-bound mitochondrial abc transporter abcb10 from biortus
    32% identity, 80% coverage of query (87.8 bits)

6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
    27% identity, 86% coverage of query (87.4 bits)

6b89A E. Coli lptb in complex with adp and novobiocin
    27% identity, 86% coverage of query (87.4 bits)

4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
    27% identity, 86% coverage of query (87.4 bits)

6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
    27% identity, 86% coverage of query (87.4 bits)

6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
    27% identity, 86% coverage of query (87.4 bits)

6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
    27% identity, 86% coverage of query (87.4 bits)

ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
    31% identity, 80% coverage of query (87.4 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    29% identity, 85% coverage of query (87.0 bits)

2pmkA Crystal structures of an isolated abc-atpase in complex with tnp-adp
    30% identity, 83% coverage of query (86.3 bits)

2ff7A The abc-atpase of the abc-transporter hlyb in the adp bound state
    30% identity, 83% coverage of query (86.3 bits)

7sgrE / Q8FDZ8 Structure of hemolysin a secretion system hlyb/d complex (see paper)
    31% identity, 80% coverage of query (86.3 bits)

6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
    27% identity, 86% coverage of query (85.9 bits)

3b5jA Crystal structures of the s504a mutant of an isolated abc-atpase in complex with tnp-adp
    30% identity, 83% coverage of query (85.5 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    31% identity, 74% coverage of query (85.1 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    31% identity, 74% coverage of query (85.1 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    31% identity, 74% coverage of query (85.1 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    31% identity, 74% coverage of query (85.1 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    31% identity, 74% coverage of query (85.1 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    31% identity, 74% coverage of query (85.1 bits)

1q12A Crystal structure of the atp-bound e. Coli malk
    31% identity, 74% coverage of query (84.7 bits)

8dckA Structure of hemolysin a secretion system hlyb/d complex, atp-bound
    31% identity, 80% coverage of query (84.7 bits)

IRTA_MYCS2 / A0R6H8 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    31% identity, 79% coverage of query (84.3 bits)

3c4jA Abc protein artp in complex with atp-gamma-s
    30% identity, 76% coverage of query (84.3 bits)

3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
    30% identity, 76% coverage of query (84.3 bits)

2olkA Abc protein artp in complex with adp-beta-s
    30% identity, 76% coverage of query (84.3 bits)

2oljA Abc protein artp in complex with adp/mg2+
    30% identity, 76% coverage of query (84.3 bits)

4f4cA / P34712 The crystal structure of the multi-drug transporter (see paper)
    31% identity, 86% coverage of query (84.0 bits)

7z15I / P16678 E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
    29% identity, 83% coverage of query (84.0 bits)

3nh9A Nucleotide binding domain of human abcb6 (atp bound structure)
    30% identity, 83% coverage of query (84.0 bits)

7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp
    29% identity, 83% coverage of query (84.0 bits)

2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
    32% identity, 87% coverage of query (83.6 bits)

1g291 / Q9YGA6 Malk (see paper)
    30% identity, 88% coverage of query (83.6 bits)

2pclA / O66646 Crystal structure of abc transporter with complex (aq_297) from aquifex aeolicus vf5
    29% identity, 80% coverage of query (83.6 bits)

8k7bA Post-occluded structure of human abcb6 w546a mutant (adp/vo4-bound)
    30% identity, 83% coverage of query (83.6 bits)

7dnyB Cryo-em structure of the human abcb6 (coproporphyrin iii-bound)
    30% identity, 83% coverage of query (83.6 bits)

7dnzB Cryo-em structure of the human abcb6 (hemin and gsh-bound)
    30% identity, 83% coverage of query (83.2 bits)

7dnzA / Q9NP58 Cryo-em structure of the human abcb6 (hemin and gsh-bound) (see paper)
    30% identity, 83% coverage of query (83.2 bits)

FtsE / b3463 cell division protein FtsE from Escherichia coli K-12 substr. MG1655 (see 9 papers)
FTSE_ECOLI / P0A9R7 Cell division ATP-binding protein FtsE from Escherichia coli (strain K12) (see 4 papers)
ftsE cell division ATP-binding protein ftsE from Escherichia coli K12 (see 3 papers)
    32% identity, 76% coverage of query (82.8 bits)

8w6iD / P0A9R7 Cryo-em structure of escherichia coli str k12 ftsex complex with atp- gamma-s in peptidisc
    32% identity, 76% coverage of query (82.8 bits)

ABCB6_HUMAN / Q9NP58 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter; EC 7.6.2.5 from Homo sapiens (Human) (see 23 papers)
TC 3.A.1.210.6 / Q9NP58 Mitochondrial outer membrane/lysosome anionic porphyrin uptake half ABC transporter, ABCB6. Expressed in many mammalian tissues (including fetal liver) in response to intracellular porphyrin. Porphyrin uptake activates de novo porphyrin (haem) biosynthesis from Homo sapiens (Human) (see 7 papers)
ABCB6 / RF|NP_005680.1 ATP-binding cassette sub-family B member 6, mitochondrial from Homo sapiens (see paper)
    30% identity, 83% coverage of query (82.8 bits)

3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
    29% identity, 76% coverage of query (82.8 bits)

1xefA Crystal structure of the atp/mg2+ bound composite dimer of hlyb-nbd
    29% identity, 86% coverage of query (82.4 bits)

7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation
    28% identity, 83% coverage of query (82.4 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    29% identity, 81% coverage of query (82.4 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    29% identity, 81% coverage of query (82.4 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    29% identity, 81% coverage of query (82.4 bits)

7eklA Mitochondrial outer membrane protein
    30% identity, 83% coverage of query (82.0 bits)

ABCG5_MOUSE / Q99PE8 ATP-binding cassette sub-family G member 5; Sterolin-1; EC 7.6.2.- from Mus musculus (Mouse) (see 15 papers)
    29% identity, 97% coverage of query (81.6 bits)

1f3oA / Q58206 Crystal structure of mj0796 atp-binding cassette (see paper)
    28% identity, 74% coverage of query (81.3 bits)

8hd0A Cell divisome spg hydrolysis machinery ftsex-envc
    32% identity, 76% coverage of query (81.3 bits)

ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
    31% identity, 79% coverage of query (80.9 bits)

7ahhC Opua inhibited inward-facing, sbd docked
    31% identity, 76% coverage of query (80.9 bits)

7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
    31% identity, 76% coverage of query (80.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory