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Searching for up to 100 curated homologs for Echvi_3166 FitnessBrowser__Cola:Echvi_3166 (500 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4ga6A / Q5JCX3 Crystal structure of amp phosphorylasE C-terminal deletion mutant in complex with substrates (see paper)
    42% identity, 89% coverage of query (305 bits)

deoA / Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see 2 papers)
AMPPA_THEKO / Q5JCX3 AMP phosphorylase; AMPpase; Nucleoside monophosphate phosphorylase; NMP phosphorylase; EC 2.4.2.57 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 3 papers)
Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis (see 3 papers)
    42% identity, 89% coverage of query (305 bits)

4ga4A Crystal structure of amp phosphorylase n-terminal deletion mutant
    45% identity, 78% coverage of query (298 bits)

PDP_BACSU / P39142 Pyrimidine-nucleoside phosphorylase; PYNP; Py-NPase; EC 2.4.2.2 from Bacillus subtilis (strain 168) (see paper)
pdp / GB|CAB15976.2 pyrimidine-nucleoside phosphorylase; EC 2.4.2.2 from Bacillus subtilis (see paper)
    31% identity, 74% coverage of query (143 bits)

5olnB / P39142 X-ray structure of the complex pyrimidine-nucleoside phosphorylase from bacillus subtilis at 1.88 a (see paper)
    31% identity, 74% coverage of query (143 bits)

Build an alignment

Build an alignment for Echvi_3166 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

A0A0D1XZI7 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Aneurinibacillus migulanus (see paper)
    29% identity, 74% coverage of query (140 bits)

7m7kB Crystal structure of uridine bound to geobacillus thermoglucosidasius pyrimidine nucleoside phosphorylase pynp
    30% identity, 73% coverage of query (135 bits)

A0A178U4P5 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Parageobacillus thermoglucosidasius (see paper)
    30% identity, 73% coverage of query (134 bits)

1brwA / P77836 The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation (see paper)
    30% identity, 74% coverage of query (132 bits)

1brwB The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation
    30% identity, 74% coverage of query (132 bits)

Q72HS4 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Thermus thermophilus (see paper)
    30% identity, 76% coverage of query (131 bits)

Q5SHF9 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Thermus thermophilus (see paper)
    29% identity, 77% coverage of query (130 bits)

A0A0E2M090 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Lacticaseibacillus paracasei (see paper)
    29% identity, 75% coverage of query (129 bits)

pdp / P77836 pyrimidine-nucleoside phosphorylase monomer (EC 2.4.2.3; EC 2.4.2.2) from Geobacillus stearothermophilus (see 4 papers)
PDP_GEOSE / P77836 Pyrimidine-nucleoside phosphorylase; PYNP; Py-NPase; EC 2.4.2.2 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
P77836 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Geobacillus stearothermophilus (see 2 papers)
pyn / GB|BAA13512.1 pyrimidine-nucleoside phosphorylase; EC 2.4.2.2 from Geobacillus stearothermophilus (see paper)
pyn / BAA13512.1 pyrimidine nucleoside phosphorylase from Geobacillus stearothermophilus (see paper)
    30% identity, 72% coverage of query (129 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory