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Searching for up to 100 curated homologs for Echvi_3219 FitnessBrowser__Cola:Echvi_3219 (343 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q8L3C9 alcohol dehydrogenase (EC 1.1.1.1) from Flavobacterium frigidimaris (see paper)
    73% identity, 99% coverage of query (533 bits)

6n7lC / A0A077EGR8 Crystal structure of an alcohol dehydrogenase from elizabethkingia anophelis nuhp1
    72% identity, 99% coverage of query (518 bits)

RR42_RS34260 Alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus basilensis FW507-4G11
    68% identity, 98% coverage of query (478 bits)

furX / Q46UZ9 furfuryl alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
    66% identity, 99% coverage of query (476 bits)

1lluA / Q9HTD9 The ternary complex of pseudomonas aeruginosa alcohol dehydrogenase with its coenzyme and weak substrate (see paper)
    67% identity, 99% coverage of query (474 bits)

3s2eA / Q46UZ9 Crystal structure of furx nadh complex 1
    66% identity, 98% coverage of query (473 bits)

3s2fE Crystal structure of furx nadh:furfural
    66% identity, 98% coverage of query (473 bits)

3s2fA Crystal structure of furx nadh:furfural
    66% identity, 98% coverage of query (473 bits)

3s2eE Crystal structure of furx nadh complex 1
    66% identity, 98% coverage of query (473 bits)

3meqA / A0A0H3G9R2 Crystal structure of alcohol dehydrogenase from brucella melitensis
    66% identity, 99% coverage of query (466 bits)

ADH_MORSE / Q8GIX7 Alcohol dehydrogenase; ADH; EC 1.1.1.1 from Moraxella sp. (strain TAE123) (see 3 papers)
Q8GIX7 alcohol dehydrogenase (EC 1.1.1.1) from Moraxella sp. (see paper)
    65% identity, 98% coverage of query (454 bits)

4z6kA / Q8GIX7 Alcohol dehydrogenase from the antarctic psychrophile moraxella sp. Tae 123
    65% identity, 98% coverage of query (454 bits)

6z42A / E1V3M3 The low resolution structure of a zinc-dependent alcohol dehydrogenase from halomonas elongata.
    66% identity, 99% coverage of query (451 bits)

Q6RS93 alcohol dehydrogenase (EC 1.1.1.1) from Parageobacillus thermoglucosidasius (see paper)
    61% identity, 98% coverage of query (419 bits)

P42328 alcohol dehydrogenase (EC 1.1.1.1) from Geobacillus stearothermophilus (see 8 papers)
1rjwA / P42328 Crystal structure of NAD(+)-dependent alcohol dehydrogenase from bacillus stearothermophilus strain lld-r (see paper)
    60% identity, 98% coverage of query (413 bits)

P12311 Alcohol dehydrogenase; ADH-T; EC 1.1.1.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus)
    60% identity, 98% coverage of query (412 bits)

3piiA Crystal structure of mutant of ht- alcohol dehydrogenase with substrate analogue butyramide
    60% identity, 98% coverage of query (411 bits)

6iqdA / P42327 Crystal structure of alcohol dehydrogenase from geobacillus stearothermophilus (see paper)
    59% identity, 98% coverage of query (409 bits)

adhA / Q8NLX9 Zn2+-dependent alcohol dehydrogenase (EC 1.1.1.1; EC 1.1.1.244) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 5 papers)
    53% identity, 98% coverage of query (377 bits)

ADH2 / GB|CAA21988.1 alcohol dehydrogenase 2; EC 1.1.1.1 from Candida albicans (see paper)
    45% identity, 99% coverage of query (291 bits)

H9ZGN0 alcohol dehydrogenase (EC 1.1.1.1) from Ogataea angusta (see paper)
    45% identity, 99% coverage of query (288 bits)

Q9P6C8 alcohol dehydrogenase (EC 1.1.1.1) from Neurospora crassa (see paper)
    43% identity, 99% coverage of query (285 bits)

A0A060TBM3 alcohol dehydrogenase (EC 1.1.1.1) from Blastobotrys adeninivorans (see paper)
    45% identity, 99% coverage of query (284 bits)

E3UTQ9 allyl-alcohol dehydrogenase (EC 1.1.1.54) from Fusarium oxysporum (see paper)
    43% identity, 99% coverage of query (281 bits)

ADH3 / P07246 alcohol dehydrogenase III (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH3_YEAST / P07246 Alcohol dehydrogenase 3, mitochondrial; Alcohol dehydrogenase III; ADHIII; YADH-3; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
    43% identity, 99% coverage of query (276 bits)

V9SCJ1 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    43% identity, 99% coverage of query (274 bits)

A1IIA3 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    43% identity, 99% coverage of query (273 bits)

A1IIA4 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    43% identity, 99% coverage of query (273 bits)

Q9CEN0 alcohol dehydrogenase (EC 1.1.1.1) from Lactococcus lactis subsp. lactis (see paper)
    45% identity, 98% coverage of query (273 bits)

G3FFC9 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    43% identity, 99% coverage of query (272 bits)

4eezB / D2BLA0 Crystal structure of lactococcus lactis alcohol dehydrogenase variant re1 (see paper)
    45% identity, 98% coverage of query (271 bits)

ADH2 / P00331 alcohol dehydrogenase II (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH2_YEAST / P00331 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADHII; YADH-2; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
    42% identity, 99% coverage of query (270 bits)

5yatA / C4R0S8 Crystal structure of mitochondrial alcohol dehydrogenase isozyme iii from komagataella phaffii gs115 (see paper)
    44% identity, 99% coverage of query (268 bits)

5envA / P00330 Yeast alcohol dehydrogenase with bound coenzyme (see paper)
    41% identity, 99% coverage of query (266 bits)

ADH1 / P00330 alcohol dehydrogenase 1 (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH1_YEAST / P00330 Alcohol dehydrogenase 1; Alcohol dehydrogenase I; ADHI; NADH-dependent methylglyoxal reductase; YADH-1; EC 1.1.1.1; EC 1.1.1.54; EC 1.1.1.78 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 12 papers)
    41% identity, 99% coverage of query (266 bits)

B6UQD0 alcohol dehydrogenase (EC 1.1.1.1) from Saccharomyces pastorianus (see 2 papers)
    41% identity, 99% coverage of query (266 bits)

4w6zA Yeast alcohol dehydrogenase i, saccharomyces cerevisiae fermentative enzyme
    41% identity, 99% coverage of query (266 bits)

ADH1_EMENI / P08843 Alcohol dehydrogenase 1; Alcohol dehydrogenase I; ADH I; EC 1.1.1.1 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
alcA alcohol dehydrogenase 1; EC 1.1.1.1 from Emericella nidulans (see 3 papers)
    43% identity, 99% coverage of query (265 bits)

YddN / b1478 ethanol dehydrogenase / alcohol dehydrogenase (EC 1.1.1.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
adhP / P39451 ethanol dehydrogenase / alcohol dehydrogenase (EC 1.1.1.1) from Escherichia coli (strain K12) (see 5 papers)
4gkvB / P39451 Structure of escherichia coli adhp (ethanol-inducible dehydrogenase) with bound NAD (see paper)
    47% identity, 99% coverage of query (263 bits)

A0A1D8PP43 alcohol dehydrogenase (EC 1.1.1.1); 2-oxoaldehyde dehydrogenase (NAD+) (EC 1.2.1.23) from Candida albicans (see paper)
    44% identity, 99% coverage of query (262 bits)

ADH5 / P38113 alcohol dehydrogenase V (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH5_YEAST / P38113 Alcohol dehydrogenase 5; Alcohol dehydrogenase V; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    40% identity, 99% coverage of query (261 bits)

ADH2_YARLI / F2Z678 Alcohol dehydrogenase 2; EC 1.1.1.1 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
    43% identity, 99% coverage of query (261 bits)

ADH1 alcohol dehydrogenase from Candida albicans (see 11 papers)
    43% identity, 99% coverage of query (260 bits)

CH_124188 alcohol dehydrogenase 1 alcohol dehydrogenase [Cochliobolus lunatus] from Magnaporthe grisea 70-15 (see 2 papers)
    42% identity, 99% coverage of query (259 bits)

ADH_SCHPO / P00332 Alcohol dehydrogenase; EC 1.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
    40% identity, 99% coverage of query (236 bits)

A3MVR8 alcohol dehydrogenase (EC 1.1.1.1) from Pyrobaculum calidifontis (see paper)
    39% identity, 98% coverage of query (213 bits)

NOTN_ASPSM / E1ACQ9 Alcohol dehydrogenase notN; Notoamide biosynthesis cluster protein N; EC 1.1.1.1 from Aspergillus sp. (strain MF297-2) (see 3 papers)
    34% identity, 99% coverage of query (192 bits)

ADH2_EMENI / P54202 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
alcB alcohol dehydrogenase 2; EC 1.1.1.1 from Emericella nidulans (see paper)
    36% identity, 99% coverage of query (190 bits)

Q9Y9P9 alcohol dehydrogenase (EC 1.1.1.1) from Aeropyrum pernix (see 3 papers)
    36% identity, 97% coverage of query (189 bits)

1h2bB / Q9Y9P9 Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon aeropyrum pernix at 1.65a resolution (see paper)
    36% identity, 97% coverage of query (188 bits)

YahK / b0325 aldehyde reductase, NADPH-dependent (EC 1.1.1.2; EC 1.1.1.55) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yahK / P75691 aldehyde reductase, NADPH-dependent (EC 1.1.1.2; EC 1.1.1.55) from Escherichia coli (strain K12) (see 7 papers)
YAHK_ECOLI / P75691 Aldehyde reductase YahK; Zinc-dependent alcohol dehydrogenase YahK; EC 1.1.1.2 from Escherichia coli (strain K12) (see 2 papers)
yahK / MB|P75691 zinc-type alcohol dehydrogenase-like protein yahK from Escherichia coli K12 (see paper)
    34% identity, 98% coverage of query (184 bits)

P9WQC5 NADP-dependent alcohol dehydrogenase C; EC 1.1.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    32% identity, 99% coverage of query (184 bits)

CH_124303 alcohol dehydrogenase 1 from Magnaporthe grisea 70-15 (see paper)
    35% identity, 99% coverage of query (182 bits)

MTD / Q38707 mannitol dehydrogenase (EC 1.1.1.255) from Apium graveolens (see paper)
Q38707 mannitol dehydrogenase (EC 1.1.1.255) from Apium graveolens (see paper)
    34% identity, 96% coverage of query (182 bits)

1uufA / P75691 Crystal structure of a zinc-type alcohol dehydrogenase-like protein yahk
    34% identity, 98% coverage of query (182 bits)

F6L7F5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Camellia sinensis (see paper)
    33% identity, 96% coverage of query (181 bits)

GEDH1 / Q2KNL6 geraniol dehydrogenase (EC 1.1.1.183) from Ocimum basilicum (see paper)
GEDH1_OCIBA / Q2KNL6 Geraniol dehydrogenase 1; ObaGEDH1; EC 1.1.1.183 from Ocimum basilicum (Sweet basil) (see paper)
Q2KNL6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Ocimum basilicum (see paper)
    36% identity, 92% coverage of query (180 bits)

T1WUT6 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    36% identity, 91% coverage of query (179 bits)

T1WVG5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    34% identity, 91% coverage of query (179 bits)

T1WW77 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    34% identity, 96% coverage of query (179 bits)

ADHC1_MYCS2 / P0CH36 NADP-dependent alcohol dehydrogenase C 1; Ms-ADHC 1; EC 1.1.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
ADHC2_MYCS2 / P0CH37 NADP-dependent alcohol dehydrogenase C 2; Ms-ADHC 2; EC 1.1.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
    32% identity, 98% coverage of query (178 bits)

A0A023RBJ1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    36% identity, 92% coverage of query (178 bits)

adhA / C0SPA5 S-(hydroxymethyl)bacillithiol dehydrogenase (EC 1.1.1.306) from Bacillus subtilis (strain 168) (see 2 papers)
ADHA_BACSU / C0SPA5 Probable formaldehyde dehydrogenase AdhA; EC 1.1.1.- from Bacillus subtilis (strain 168) (see paper)
    33% identity, 91% coverage of query (178 bits)

Q8H0L8 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Solanum tuberosum (see paper)
    36% identity, 92% coverage of query (178 bits)

A0A125SUY5 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mycobacterium sp. (see paper)
    30% identity, 99% coverage of query (177 bits)

T1WWR8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    34% identity, 96% coverage of query (177 bits)

T1WUU2 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    35% identity, 93% coverage of query (176 bits)

2eerB / Q96XE0 Structural study of project id st2577 from sulfolobus tokodaii strain7
    34% identity, 97% coverage of query (176 bits)

SAD / Q94G59 sinapyl alcohol dehydrogenase (EC 1.1.1.195) from Populus tremuloides (see paper)
    35% identity, 93% coverage of query (176 bits)

T1WWB9 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    35% identity, 95% coverage of query (175 bits)

1yqdA / Q94G59 Sinapyl alcohol dehydrogenase complexed with NADP+ (see paper)
    35% identity, 93% coverage of query (174 bits)

A0A1D6BJ11 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Triticum aestivum (see paper)
    35% identity, 96% coverage of query (174 bits)

A1R6C3 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Paenarthrobacter aurescens (see paper)
    33% identity, 94% coverage of query (174 bits)

CAD7 / Q02971 cinnamyl alcohol dehydrogenase 7 (EC 1.1.1.195) from Arabidopsis thaliana (see 2 papers)
CADH7_ARATH / Q02971 Cinnamyl alcohol dehydrogenase 7; AtCAD7; Cinnamyl alcohol dehydrogenase-like protein B; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    34% identity, 93% coverage of query (172 bits)

chnD / Q9F7D8 6-hydroxyhexanoate dehydrogenase (EC 1.1.1.258) from Acinetobacter sp. (strain SE19) (see paper)
    35% identity, 97% coverage of query (171 bits)

CADH9_ARATH / P42734 Probable cinnamyl alcohol dehydrogenase 9; AtCAD9; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    35% identity, 92% coverage of query (170 bits)

F9VMI9 alcohol dehydrogenase (EC 1.1.1.1) from Sulfurisphaera tokodaii (see paper)
    34% identity, 97% coverage of query (169 bits)

CADH2_ARATH / Q9SJ25 Cinnamyl alcohol dehydrogenase 2; AtCAD2; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    34% identity, 92% coverage of query (169 bits)

Q9ATW1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Fragaria x ananassa (see paper)
    34% identity, 92% coverage of query (166 bits)

CADH8_ARATH / Q02972 Cinnamyl alcohol dehydrogenase 8; AtCAD8; NAD-dependent mannitol dehydrogenase 2; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    34% identity, 92% coverage of query (166 bits)

ADHA_SYNY3 / P74721 Aldehyde reductase AdhA; Alcohol dehydrogenase AdhA; EC 1.1.1.2 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
P74721 alcohol dehydrogenase (EC 1.1.1.1) from Synechocystis sp. PCC 6803 (see paper)
    30% identity, 98% coverage of query (166 bits)

CADH3_ARATH / Q9SJ10 Cinnamyl alcohol dehydrogenase 3; AtCAD3; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    34% identity, 92% coverage of query (166 bits)

K9S0X0 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens var. hirtella (see paper)
    34% identity, 91% coverage of query (165 bits)

5z0cA / J7JYU1 Nerol dehydrogenase from persicaria minor (see paper)
    34% identity, 93% coverage of query (158 bits)

6k3gB / Q6V4H0 Crystal structure of 10-hydroxygeraniol dehydrogenase from cantharanthus roseus in complex with NADP+ (see paper)
    33% identity, 93% coverage of query (157 bits)

7cguA / A0A8A5L0G9 Crystal structure of abhar
    33% identity, 92% coverage of query (154 bits)

1r37A Alcohol dehydrogenase from sulfolobus solfataricus complexed with NAD(h) and 2-ethoxyethanol
    33% identity, 97% coverage of query (152 bits)

P39462 alcohol dehydrogenase (EC 1.1.1.1) from Saccharolobus solfataricus (see 7 papers)
1jvbA / P39462 Alcohol dehydrogenase from the archaeon sulfolobus solfataricus (see paper)
    33% identity, 97% coverage of query (152 bits)

P39462 NAD-dependent alcohol dehydrogenase; EC 1.1.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
    33% identity, 97% coverage of query (152 bits)

D0ITF8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Helicobacter pylori (see paper)
3twoB / D0ITF8 The crystal structure of cad from helicobacter pylori complexed with NADP(h) (see paper)
    30% identity, 95% coverage of query (151 bits)

5vktA / C5XC49 Cinnamyl alcohol dehydrogenases (sbcad4) from sorghum bicolor (l.) Moench (see paper)
    32% identity, 91% coverage of query (147 bits)

Build an alignment

Build an alignment for Echvi_3219 and 91 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

8a3nB / W8JWW7 Geissoschizine synthase from catharanthus roseus - binary complex with NADP+ (see paper)
    29% identity, 96% coverage of query (142 bits)

8b25B / A0A5B8X8Z0 Dihydroprecondylocarpine acetate synthase 2 from tabernanthe iboga - stemmadenine acetate bound structure (see paper)
    32% identity, 95% coverage of query (142 bits)

8b1vA Dihydroprecondylocarpine acetate synthase 2 from tabernanthe iboga
    32% identity, 95% coverage of query (142 bits)

araDH / Q97YM2 D-arabinose 1-dehydrogenase subunit (EC 1.1.1.427) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 2 papers)
ARADH_SACS2 / Q97YM2 D-arabinose 1-dehydrogenase (NADP(+)); AraDH; D-Ara dehydrogenase; EC 1.1.1.427 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
Q97YM2 D-threo-aldose 1-dehydrogenase (EC 1.1.1.122) from Saccharolobus solfataricus (see 2 papers)
    29% identity, 97% coverage of query (140 bits)

6ffxA Crystal structure of r. Ruber adh-a, mutant f43h (see paper)
    32% identity, 97% coverage of query (140 bits)

5fi3A / A0A0F6SD02 Heteroyohimbine synthase thas1 from catharanthus roseus - complex with NADP+ (see paper)
    30% identity, 93% coverage of query (138 bits)

6isvB / M5A8V4 Structure of acetophenone reductase from geotrichum candidum nbrc 4597 in complex with NAD (see paper)
    32% identity, 99% coverage of query (138 bits)

5o9dA Crystal structure of r. Ruber adh-a, mutant y294f, w295a, y54f, f43h, h39y
    31% identity, 97% coverage of query (138 bits)

7bu3A Structure of alcohol dehydrogenase yjgb in complex with NADP from escherichia coli
    31% identity, 97% coverage of query (137 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory