Searching for up to 100 curated homologs for Echvi_4177 FitnessBrowser__Cola:Echvi_4177 (327 a.a.)
Found high-coverage hits (≥70%) to 92 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ALKR4_ARATH / Q93ZN2 Probable aldo-keto reductase 4; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
44% identity, 97% coverage of query (285 bits)
AKR1_SOYBN / C6TBN2 Probable aldo-keto reductase 1; GmAKR1; EC 1.1.1.- from Glycine max (Soybean) (Glycine hispida) (see paper)
45% identity, 95% coverage of query (278 bits)
PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
44% identity, 96% coverage of query (265 bits)
STR7_STRTC / A0A3B1EFQ1 Aldo-keto reductase str7; Strobilurin A biosynthesis cluster protein r7; EC 1.1.1.- from Strobilurus tenacellus (see 3 papers)
41% identity, 96% coverage of query (239 bits)
YAKC_SCHPO / Q09923 Aldo-keto reductase yakc [NADP(+)]; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
yak3 aldose reductase YakC from Schizosaccharomyces pombe (see 3 papers)
41% identity, 98% coverage of query (238 bits)
3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
42% identity, 94% coverage of query (235 bits)
FDB38_GIBM7 / W7N2Q9 Aldo-keto reductase FVEG_12638; Fusarium detoxification of benzoxazolinone cluster 2 protein FVEG_12638; FDB2 cluster protein FVEG_12638; EC 1.1.1.- from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) (see 4 papers)
35% identity, 98% coverage of query (190 bits)
FDB25_FUSPC / K3VD70 Aldo-keto reductase FPSE_08125; Fusarium detoxification of benzoxazolinone cluster protein FPSE_08125; FDB cluster protein FPSE_08125; EC 1.1.1.- from Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot fungus) (see 3 papers)
36% identity, 97% coverage of query (182 bits)
IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
34% identity, 92% coverage of query (176 bits)
1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
34% identity, 91% coverage of query (173 bits)
YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
33% identity, 96% coverage of query (172 bits)
GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
32% identity, 94% coverage of query (162 bits)
1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
32% identity, 94% coverage of query (161 bits)
8hnqA / A0A6B8QJ47 The structure of a alcohol dehydrogenase akr13b2 with NADP
33% identity, 90% coverage of query (160 bits)
6ow0A / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
32% identity, 94% coverage of query (157 bits)
6ow0B / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
32% identity, 94% coverage of query (155 bits)
YI7E_SCHPO / Q9P7U2 Putative aryl-alcohol dehydrogenase C977.14c; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 91% coverage of query (150 bits)
F2YCN5 D-xylose reductase (EC 1.1.1.307) from Zymomonas mobilis subsp. mobilis (see paper)
35% identity, 91% coverage of query (148 bits)
CSH1 member of aldo-keto reductase family from Candida albicans (see 5 papers)
32% identity, 90% coverage of query (147 bits)
mtmW / Q194Q1 mithramycin dehydrogenase from Streptomyces argillaceus (see 2 papers)
31% identity, 94% coverage of query (147 bits)
KCAB_ARATH / O23016 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; Potassium voltage beta 1; KV-beta1; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
34% identity, 90% coverage of query (146 bits)
YH5B_SCHPO / O94315 Uncharacterized oxidoreductase C215.11c; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
34% identity, 87% coverage of query (146 bits)
KCAB_ORYSJ / Q40648 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Oryza sativa subsp. japonica (Rice) (see paper)
33% identity, 90% coverage of query (144 bits)
IFD6 aldo-keto reductase family member from Candida albicans (see paper)
31% identity, 90% coverage of query (144 bits)
KCAB_SCHPO / O59826 Putative voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
37% identity, 87% coverage of query (143 bits)
VRDA_ASPPA / B9WYE6 Versiconal hemiacetal acetate reductase; VHA reductase; EC 1.1.1.353 from Aspergillus parasiticus (see paper)
B9WYE6 versiconal hemiacetal acetate reductase (EC 1.1.1.353) from Aspergillus parasiticus (see paper)
30% identity, 92% coverage of query (140 bits)
YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
31% identity, 91% coverage of query (140 bits)
4aubB / Q46851 The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
31% identity, 95% coverage of query (140 bits)
8hw0A / A0A6B8QIS5 The structure of akr6d1
31% identity, 89% coverage of query (139 bits)
Gpr / b3001 L-glyceraldehyde 3-phosphate reductase from Escherichia coli K-12 substr. MG1655 (see 9 papers)
gpr / Q46851 L-glyceraldehyde 3-phosphate reductase (EC 1.1.1.21) from Escherichia coli (strain K12) (see 7 papers)
GPR_ECOLI / Q46851 L-glyceraldehyde 3-phosphate reductase; GAP reductase; EC 1.1.1.- from Escherichia coli (strain K12) (see 4 papers)
31% identity, 95% coverage of query (138 bits)
Q5FQJ0 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
33% identity, 79% coverage of query (137 bits)
KCAB1_RAT / P63144 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Rattus norvegicus (Rat) (see 9 papers)
30% identity, 94% coverage of query (135 bits)
KCAB1_MOUSE / P63143 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Mus musculus (Mouse) (see 5 papers)
30% identity, 94% coverage of query (135 bits)
KCAB1_HUMAN / Q14722 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Homo sapiens (Human) (see 13 papers)
30% identity, 94% coverage of query (134 bits)
KCAB1_RABIT / Q9XT31 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Oryctolagus cuniculus (Rabbit) (see paper)
30% identity, 94% coverage of query (134 bits)
KCAB3_XENLA / Q9PTM4 Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3; EC 1.1.1.- from Xenopus laevis (African clawed frog) (see paper)
30% identity, 90% coverage of query (134 bits)
PLR1_SCHPO / O14295 Pyridoxal reductase; PL reductase; PL-red; EC 1.1.1.65 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
plr1 / RF|NP_594584.1 pyridoxal reductase Plr1; EC 1.1.1.65 from Schizosaccharomyces pombe (see 3 papers)
31% identity, 95% coverage of query (134 bits)
KCAB1_MUSPU / Q28528 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Mustela putorius (European polecat) (see paper)
30% identity, 94% coverage of query (133 bits)
PdxI / b1406 pyridoxine 4-dehydrogenase (EC 1.1.1.65) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
pdxI / P25906 pyridoxal reductase (EC 1.1.1.65) from Escherichia coli (strain K12) (see 5 papers)
PDXI_ECOLI / P25906 Pyridoxine 4-dehydrogenase; EC 1.1.1.65 from Escherichia coli (strain K12) (see 2 papers)
ydbC / MB|P25906 putative oxidoreductase ydbC from Escherichia coli K12 (see paper)
30% identity, 91% coverage of query (132 bits)
Build an alignment for Echvi_4177 and 39 homologs with ≥ 30% identity
Or download the sequences
KCAB3_RAT / Q63494 Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3; RCK beta3; EC 1.1.1.- from Rattus norvegicus (Rat) (see paper)
29% identity, 94% coverage of query (132 bits)
KCAB3_HUMAN / O43448 Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3; EC 1.1.1.- from Homo sapiens (Human) (see paper)
29% identity, 94% coverage of query (131 bits)
6hg6A / A0A1S8QGT2 Clostridium beijerinckii aldo-keto reductase cbei_3974 with NADPH (see paper)
30% identity, 93% coverage of query (131 bits)
7wf3C / Q13303 Composite map of human kv1.3 channel in apo state with beta subunits (see paper)
30% identity, 94% coverage of query (130 bits)
KCAB2_BOVIN / Q27955 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Bos taurus (Bovine) (see paper)
30% identity, 94% coverage of query (130 bits)
KCAB2_HUMAN / Q13303 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; hKvbeta2; EC 1.1.1.- from Homo sapiens (Human) (see 4 papers)
30% identity, 94% coverage of query (130 bits)
3n6qD Crystal structure of yghz from e. Coli
30% identity, 95% coverage of query (130 bits)
KCAB2_MOUSE / P62482 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; Neuroimmune protein F5; EC 1.1.1.- from Mus musculus (Mouse) (see 8 papers)
KCAB2_RAT / P62483 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Rattus norvegicus (Rat) (see 19 papers)
30% identity, 94% coverage of query (129 bits)
KCAB2_XENLA / Q9PTM5 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Xenopus laevis (African clawed frog) (see paper)
30% identity, 94% coverage of query (129 bits)
PLR2_SCHPO / O94521 Probable pyridoxal reductase 2; PL reductase 2; PL-red 2; EC 1.1.1.65 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
31% identity, 95% coverage of query (129 bits)
AAD16_YEAST / Q02895 Putative aryl-alcohol dehydrogenase AAD16; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
28% identity, 90% coverage of query (129 bits)
3eauA Voltage-dependent k+ channel beta subunit in complex with cortisone
30% identity, 94% coverage of query (129 bits)
1exbA Structure of the cytoplasmic beta subunit-t1 assembly of voltage- dependent k channels
30% identity, 94% coverage of query (129 bits)
PK81H_PSEFD / M2YMU7 Aldo-keto reductase MYCFIDRAFT_87468; PKS8-1 gene cluster protein MYCFIDRAFT_87468; EC 1.1.1.- from Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease fungus) (Mycosphaerella fijiensis) (see 2 papers)
28% identity, 91% coverage of query (127 bits)
5t79A / Q8ZNA1 X-ray crystal structure of a novel aldo-keto reductases for the biocatalytic conversion of 3-hydroxybutanal to 1,3-butanediol (see paper)
30% identity, 88% coverage of query (127 bits)
SAN2_FUSV7 / C7ZBE5 Aldo-keto reductase NECHADRAFT_45914; Sansalvamide biosynthesis cluster protein NECHADRAFT_45914; EC 1.1.1.- from Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4) (Fusarium solani subsp. pisi) (see paper)
27% identity, 91% coverage of query (127 bits)
3erpA Structure of idp01002, a putative oxidoreductase from and essential gene of salmonella typhimurium
30% identity, 88% coverage of query (127 bits)
4aubE The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate
30% identity, 93% coverage of query (126 bits)
6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
29% identity, 92% coverage of query (122 bits)
Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
29% identity, 92% coverage of query (122 bits)
AFLE_ASPPU / Q00258 Norsolorinic acid reductase A; Aflatoxin biosynthesis protein E; EC 1.1.1.- from Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) (see 2 papers)
nor / AAC49166.1 norsolorinic acid reductase from Aspergillus parasiticus (see paper)
28% identity, 91% coverage of query (122 bits)
6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
29% identity, 92% coverage of query (122 bits)
5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
29% identity, 92% coverage of query (122 bits)
AMT2_ALTAL / Q75ZG2 Aldo-keto reductase AMT2; AM-toxin biosynthesis protein 2; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
29% identity, 91% coverage of query (121 bits)
AFTS1_ALTAL / Q75ZG3 Aldo-keto reductase AFTS1; AF-toxin biosynthesis protein S1; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
28% identity, 93% coverage of query (119 bits)
4aubF / Q46851 The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
29% identity, 93% coverage of query (115 bits)
YgdS / b2834 putative NADP(H)-dependent aldo-keto reductase Tas from Escherichia coli K-12 substr. MG1655 (see 6 papers)
1lqaA / P0A9T4 Tas protein from escherichia coli in complex with NADPH (see paper)
tas protein Tas from Escherichia coli str. K12 substr. MG1655 (see paper)
28% identity, 93% coverage of query (95.9 bits)
P0A9T4 Protein tas from Escherichia coli (strain K12)
28% identity, 93% coverage of query (95.9 bits)
6ciaA / A6T7Q7 Crystal structure of aldo-keto reductase from klebsiella pneumoniae in complex with NADPH.
27% identity, 93% coverage of query (93.2 bits)
4wghA Crystal structure of aldo/keto reductase from klebsiella pneumoniae in complex with NADP and acetate at 1.8 a resolution
26% identity, 89% coverage of query (92.8 bits)
5c7hA / Q92NR7 Crystal structure of aldo-keto reductase from sinorhizobium meliloti 1021 in complex with NADPH
29% identity, 90% coverage of query (87.8 bits)
4pmjA Crystal structure of a putative oxidoreductase from sinorhizobium meliloti 1021 in complex with NADP
29% identity, 90% coverage of query (87.8 bits)
7svqA / Q6BDJ2 Crystal structure of l-galactose dehydrogenase from spinacia oleracea in complex with NAD+ (see paper)
28% identity, 89% coverage of query (85.5 bits)
7bc1A / A9CEY6 Crystal structure of aldo-keto reductase from agrobacterium tumefaciens in a ternary complex with NADPH and glucose (see paper)
26% identity, 81% coverage of query (79.3 bits)
smoB / A9CEY6 6-dehydroglucose reductase monomer (EC 1.1.1.432) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
DHGRD_AGRFC / A9CEY6 6-dehydroglucose reductase; SQ monooxygenase cluster protein B; EC 1.1.1.432 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
26% identity, 81% coverage of query (79.0 bits)
7twzA / A0A0H3GP70 Crystal structure of NADP-linked putative oxidoreductase from klebsiella pneumoniae
25% identity, 94% coverage of query (69.3 bits)
7s5fB / A0A1U9WT24 Crystal structure of mannose-6-phosphate reductase from celery (apium graveolens) leaves with NADP+ and mannonic acid bound (see paper)
22% identity, 92% coverage of query (68.9 bits)
3krbA / A8BGX6 Structure of aldose reductase from giardia lamblia at 1.75a resolution (see paper)
22% identity, 89% coverage of query (63.9 bits)
P76187 Oxidoreductase YdhF; EC 1.-.-.- from Escherichia coli (strain K12)
25% identity, 83% coverage of query (63.2 bits)
1og6C / P76187 Ydhf, an aldo-keto reductase from e.Coli complexed with NADPH
25% identity, 83% coverage of query (62.0 bits)
2vdgA Barley aldose reductase 1 complex with butanol
23% identity, 84% coverage of query (59.7 bits)
2bgsA / P23901 Holo aldose reductase from barley (see paper)
23% identity, 84% coverage of query (59.7 bits)
CPRC2_CANPA / Q76L36 NADPH-dependent conjugated polyketone reductase C2; CPR-C2; 2-dehydropantolactone reductase; Ketopantoyl-lactone reductase; EC 1.1.1.-; EC 1.1.1.358 from Candida parapsilosis (Yeast) (see 4 papers)
Q76L36 2-dehydropantolactone reductase (Si-specific) (EC 1.1.1.214); 2-dehydropantolactone reductase (EC 1.1.1.358) from Candida parapsilosis (see 4 papers)
25% identity, 79% coverage of query (58.9 bits)
4h8nA / Q76L36 Crystal structure of conjugated polyketone reductase c2 from candida parapsilosis complexed with NADPH (see paper)
25% identity, 79% coverage of query (58.9 bits)
5ketA / A0A140CVV2 Structure of the aldo-keto reductase from coptotermes gestroi (see paper)
24% identity, 88% coverage of query (56.2 bits)
5zcmA / A0A0M4HL56 Crystal structure of xylose reductase from debaryomyces nepalensis in complex with NADP-dtt adduct (see paper)
24% identity, 91% coverage of query (55.5 bits)
A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
23% identity, 93% coverage of query (53.5 bits)
XYL1_CANBO / Q8X195 NADPH-dependent D-xylose reductase; XR; EC 1.1.1.307 from Candida boidinii (Yeast) (see 5 papers)
Q8X195 D-xylose reductase (EC 1.1.1.307) from [Candida] boidinii (see paper)
22% identity, 91% coverage of query (51.6 bits)
3cv7A Crystal structure of porcine aldehyde reductase ternary complex
22% identity, 94% coverage of query (51.2 bits)
AKR1A1 / P50578 aldehyde reductase (EC 1.1.1.2) from Sus scrofa (see paper)
AK1A1_PIG / P50578 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Sus scrofa (Pig) (see paper)
P50578 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Sus scrofa (see 2 papers)
3fx4A / P50578 Porcine aldehyde reductase in ternary complex with inhibitor (see paper)
22% identity, 94% coverage of query (51.2 bits)
3h4gA Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
22% identity, 94% coverage of query (51.2 bits)
AK2E4_BOMMO / H9JTG9 Aldo-keto reductase AKR2E4; 3-dehydroecdysone reductase; Aldo-keto reductase 2E; EC 1.1.1.- from Bombyx mori (Silk moth) (see paper)
22% identity, 83% coverage of query (43.9 bits)
3wczA / H9JTG9 Crystal structure of bombyx mori aldo-keto reductase (akr2e4) in complex with NADP (see paper)
22% identity, 83% coverage of query (43.5 bits)
Or start over
Lawrence Berkeley National Laboratory