Searching for up to 100 curated homologs for Echvi_4409 FitnessBrowser__Cola:Echvi_4409 (362 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
wbgU / Q7BJX9 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Plesiomonas shigelloides (see paper)
GNE_PLESH / Q7BJX9 UDP-N-acetylglucosamine 4-epimerase; UDP-GalNAc 4-epimerase; EC 5.1.3.7 from Plesiomonas shigelloides (Aeromonas shigelloides) (see 3 papers)
Q7BJX9 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Plesiomonas shigelloides (see 2 papers)
52% identity, 92% coverage of query (330 bits)
3lu1A / Q7BJX9 Crystal structure analysis of wbgu: a udp-galnac 4-epimerase (see paper)
52% identity, 92% coverage of query (325 bits)
3ruhA Alternative analogs as viable substrates of udp-hexose 4-epimerases
52% identity, 92% coverage of query (325 bits)
3rufA Alternative analogs as viable substrates of udp-hexose 4-epimerases
52% identity, 92% coverage of query (325 bits)
Q8KN66 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Pseudomonas aeruginosa (see paper)
1sb8A / Q8KN66 Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-n-acetylgalactosamine (see paper)
52% identity, 92% coverage of query (324 bits)
1sb9A Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-glucose
52% identity, 92% coverage of query (324 bits)
wbpP / Q9RHD6 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Pseudomonas aeruginosa (see 8 papers)
51% identity, 92% coverage of query (321 bits)
6dntA / D3E402 Udp-n-acetylglucosamine 4-epimerase from methanobrevibacter ruminantium m1 in complex with udp-n-acetylmuramic acid (see paper)
35% identity, 94% coverage of query (207 bits)
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
34% identity, 94% coverage of query (181 bits)
6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
33% identity, 91% coverage of query (159 bits)
6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
33% identity, 91% coverage of query (159 bits)
6pnlA / O26475 Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
31% identity, 96% coverage of query (151 bits)
6pmhA Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
31% identity, 96% coverage of query (151 bits)
GALE_MYCS2 / A0R5C5 UDP-glucose 4-epimerase; UDP-galactose 4-epimerase; Uridine diphosphate galactose 4-epimerase; EC 5.1.3.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
34% identity, 93% coverage of query (150 bits)
7ystA / P9WN67 Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chain b from mycobacterium tuberculosis
33% identity, 93% coverage of query (146 bits)
galE1 / P9WN67 UDP-galactose/glucose 4-epimerase subunit (EC 5.1.3.7; EC 5.1.3.2) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WN67 UDP-glucose 4-epimerase (EC 5.1.3.2) from Mycobacterium tuberculosis (see paper)
33% identity, 93% coverage of query (146 bits)
7ysmA Crystal structure of udp-glucose 4-epimerase (rv3634c) co-crystallized with udp-n-acetylglucosamine from mycobacterium tuberculosis
33% identity, 93% coverage of query (146 bits)
7ys9A Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chaina from mycobacterium tuberculosis
33% identity, 93% coverage of query (146 bits)
UAE / Q868I5 UDP-N-acetylglucosamine 4'-epimerase (EC 5.1.3.7) from Giardia intestinalis (see 7 papers)
30% identity, 95% coverage of query (144 bits)
5u4qA 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
31% identity, 94% coverage of query (140 bits)
GAE2_ARATH / Q9LPC1 UDP-glucuronate 4-epimerase 2; UDP-glucuronic acid epimerase 2; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LPC1 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
32% identity, 95% coverage of query (138 bits)
gla / P96481 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Streptococcus pneumoniae (see 2 papers)
30% identity, 95% coverage of query (136 bits)
Q6K9M5 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Oryza sativa (see paper)
32% identity, 96% coverage of query (134 bits)
GAE4 / O22141 subunit of UDP-GlcA 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
GAE4_ARATH / O22141 UDP-glucuronate 4-epimerase 4; UDP-glucuronic acid epimerase 4; AtUGlcAE1; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O22141 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 4 papers)
31% identity, 97% coverage of query (132 bits)
Q304Y2 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Zea mays (see paper)
32% identity, 96% coverage of query (131 bits)
GAE3_ARATH / O81312 UDP-glucuronate 4-epimerase 3; UDP-glucuronic acid epimerase 3; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
O81312 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
32% identity, 93% coverage of query (130 bits)
Build an alignment for Echvi_4409 and 26 homologs with ≥ 30% identity
Or download the sequences
F2NQX6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Marinithermus hydrothermalis (see paper)
29% identity, 94% coverage of query (130 bits)
UGA4E_THEGP / F8C4X8 UDP-glucuronate 4-epimerase; UGA4E; TgUGAE; EC 5.1.3.6 from Thermodesulfobacterium geofontis (strain OPF15)
30% identity, 92% coverage of query (130 bits)
GAE6_ARATH / Q9LIS3 UDP-glucuronate 4-epimerase 6; UDP-glucuronic acid epimerase 6; AtUGlcAE2; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9LIS3 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 3 papers)
32% identity, 93% coverage of query (130 bits)
GALE_LACHE / Q7WTB1 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Lactobacillus helveticus (Lactobacillus suntoryeus) (see paper)
28% identity, 93% coverage of query (128 bits)
5u4qB 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
29% identity, 94% coverage of query (127 bits)
6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
30% identity, 91% coverage of query (122 bits)
GAE1_ARATH / Q9M0B6 UDP-glucuronate 4-epimerase 1; UDP-glucuronic acid epimerase 1; AtUGlcAE3; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9M0B6 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 3 papers)
31% identity, 94% coverage of query (122 bits)
F6DEY6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Thermus thermophilus (see paper)
30% identity, 93% coverage of query (122 bits)
2p5uA / Q5SKQ2 Crystal structure of thermus thermophilus hb8 udp-glucose 4-epimerase complex with NAD
30% identity, 93% coverage of query (122 bits)
6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
30% identity, 91% coverage of query (122 bits)
6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
30% identity, 91% coverage of query (122 bits)
desIV / Q9ZGH3 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces venezuelae (see paper)
30% identity, 93% coverage of query (121 bits)
agl12 / D4GU72 dTDP-glucose-4,6-dehydratase (EC 4.2.1.46) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL12_HALVD / D4GU72 Low-salt glycan biosynthesis protein Agl12; EC 4.2.1.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
30% identity, 92% coverage of query (121 bits)
6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
29% identity, 91% coverage of query (120 bits)
1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
30% identity, 93% coverage of query (120 bits)
1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
30% identity, 93% coverage of query (119 bits)
UXS1 / Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
UXS1_ARATH / Q8VZC0 UDP-glucuronic acid decarboxylase 1; UDP-XYL synthase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
28% identity, 94% coverage of query (118 bits)
uxs1 / Q92WA4 UDP-xylose synthase 1 subunit (EC 4.1.1.35) from Rhizobium meliloti (strain 1021) (see paper)
29% identity, 93% coverage of query (117 bits)
galE / CAA89986.1 UDP-galactose 4-epimease from Corynebacterium glutamicum (see paper)
29% identity, 89% coverage of query (117 bits)
6kvcA Moee5 in complex with udp-glucose and NAD
30% identity, 94% coverage of query (117 bits)
O73960 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrococcus horikoshii (see paper)
29% identity, 88% coverage of query (116 bits)
tylA2 / Q54144 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces fradiae (see 2 papers)
29% identity, 94% coverage of query (116 bits)
A0A1J0KK43 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Albuca bracteata (see paper)
31% identity, 94% coverage of query (116 bits)
2b69A / Q8NBZ7 Crystal structure of human udp-glucoronic acid decarboxylase
27% identity, 96% coverage of query (115 bits)
UXS1_RAT / Q5PQX0 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Rattus norvegicus (Rat) (see paper)
27% identity, 96% coverage of query (115 bits)
UXS1_HUMAN / Q8NBZ7 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; hUXS; hUXS1; EC 4.1.1.35 from Homo sapiens (Human) (see 3 papers)
27% identity, 96% coverage of query (115 bits)
GAE5_ARATH / Q9STI6 UDP-glucuronate 4-epimerase 5; UDP-glucuronic acid epimerase 5; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9STI6 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 2 papers)
31% identity, 93% coverage of query (115 bits)
6kv9A / A0A003 Moee5 in complex with udp-glucuronic acid and NAD (see paper)
30% identity, 93% coverage of query (115 bits)
Q75PK7 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-2 / BAD12490.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
28% identity, 93% coverage of query (115 bits)
8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
27% identity, 94% coverage of query (115 bits)
UXS2 / Q9LZI2 subunit of UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see 3 papers)
UXS2_ARATH / Q9LZI2 UDP-glucuronic acid decarboxylase 2; UDP-XYL synthase 2; UDP-glucuronate decarboxylase 2; UGD; UXS-2; dTDP-glucose 4-6-dehydratase homolog D18; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LZI2 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
27% identity, 94% coverage of query (114 bits)
N0A0C4 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
27% identity, 94% coverage of query (114 bits)
UXS1_DANRE / Q6GMI9 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UXS-1; EC 4.1.1.35 from Danio rerio (Zebrafish) (Brachydanio rerio) (see 3 papers)
26% identity, 95% coverage of query (114 bits)
N0A8N3 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
27% identity, 92% coverage of query (113 bits)
Q75PK6 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-1 / BAD12491.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
28% identity, 91% coverage of query (113 bits)
Q8W3J1 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-4 / BAB84333.2 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
29% identity, 91% coverage of query (112 bits)
LPSL_RHIME / O54067 Probable UDP-glucuronate 4-epimerase; UDP-glucuronic acid epimerase; EC 5.1.3.6 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
28% identity, 94% coverage of query (112 bits)
A0A0H2UQY4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Streptococcus pneumoniae (see paper)
27% identity, 96% coverage of query (111 bits)
N0A9U2 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
28% identity, 96% coverage of query (111 bits)
Echvi_1472 UDP-glucose 4-epimerase (EC 5.1.3.2) from Echinicola vietnamensis KMM 6221, DSM 17526
30% identity, 94% coverage of query (111 bits)
galE / AAA63156.1 UPD-glucose-4-epimerase from Neisseria meningitidis (see paper)
28% identity, 93% coverage of query (110 bits)
gnu / Q4KXC7 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase (EC 5.1.3.26) from Escherichia coli (see paper)
26% identity, 93% coverage of query (110 bits)
TGDS_HUMAN / O95455 dTDP-D-glucose 4,6-dehydratase; EC 4.2.1.46 from Homo sapiens (Human) (see paper)
28% identity, 96% coverage of query (110 bits)
Q9ZV36 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
29% identity, 93% coverage of query (110 bits)
2udpA Udp-galactose 4-epimerase complexed with udp-phenol
28% identity, 93% coverage of query (107 bits)
1udcA Structure of udp-galactose-4-epimerase complexed with udp-mannose
28% identity, 93% coverage of query (107 bits)
GalD / b0759 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
galE / P09147 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli (strain K12) (see 38 papers)
GALE_ECOLI / P09147 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Escherichia coli (strain K12) (see 13 papers)
28% identity, 93% coverage of query (107 bits)
1udaA Structure of udp-galactose-4-epimerase complexed with udp-4-deoxy-4- fluoro-alpha-d-galactose
28% identity, 93% coverage of query (107 bits)
1naiA Udp-galactose 4-epimerase from escherichia coli, oxidized
28% identity, 93% coverage of query (107 bits)
1lrjA Crystal structure of e. Coli udp-galactose 4-epimerase complexed with udp-n-acetylglucosamine
28% identity, 93% coverage of query (107 bits)
1kvrA Udp-galactose 4-epimerase complexed with udp-phenol
27% identity, 93% coverage of query (106 bits)
7kn1A / B2FNY6 Crystal structure of udp-glucose-4-epimerase (gale) from stenotrophomonas maltophila with bound NAD and formylated udp- arabinopyranose
27% identity, 93% coverage of query (105 bits)
2q1sA / O87989 Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with nadh (see paper)
26% identity, 94% coverage of query (105 bits)
1a9yA / P09147 Udp-galactose 4-epimerase mutant s124a/y149f complexed with udp- glucose (see paper)
27% identity, 93% coverage of query (104 bits)
2q1tA Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with NAD+ and udp
26% identity, 94% coverage of query (102 bits)
2pzjA Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with NAD+
26% identity, 94% coverage of query (101 bits)
4lisA / C8VAU8 Crystal structure of udp-galactose-4-epimerase from aspergillus nidulans (see paper)
28% identity, 93% coverage of query (98.2 bits)
4twrA / Q2YKG6 Structure of udp-glucose 4-epimerase from brucella abortus
27% identity, 89% coverage of query (98.2 bits)
7xpqA Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glcnac
26% identity, 94% coverage of query (98.2 bits)
4lisB Crystal structure of udp-galactose-4-epimerase from aspergillus nidulans
28% identity, 93% coverage of query (97.8 bits)
7xpoA / C0HI30 Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glc (see paper)
26% identity, 94% coverage of query (97.8 bits)
6k0iA Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp-glc
26% identity, 92% coverage of query (96.7 bits)
6k0hA Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp-glcnac
26% identity, 92% coverage of query (96.7 bits)
6k0gA / E8MF10 Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp (see paper)
26% identity, 92% coverage of query (96.7 bits)
7k3pA / Q0P9C3 The structure of the udp-glc/glcnac 4-epimerase from the human pathogen campylobacter jejuni
25% identity, 93% coverage of query (94.7 bits)
3sxpD / B5Z7L9 Crystal structure of helicobacter pylori adp-l-glycero-d-manno- heptose-6-epimerase (rfad, hp0859) (see paper)
29% identity, 92% coverage of query (92.4 bits)
8sk0A Crystal structure of evds6 decarboxylase in ligand bound state
27% identity, 94% coverage of query (92.0 bits)
8sk0B / A0A1C5ADV9 Crystal structure of evds6 decarboxylase in ligand bound state (see paper)
27% identity, 94% coverage of query (92.0 bits)
4lk3B / Q8NBZ7 Crystal structure of human udp-xylose synthase r236a substitution (see paper)
25% identity, 96% coverage of query (91.7 bits)
2cnbA Trypanosoma brucei udp-galactose-4-epimerase in ternary complex with NAD and the substrate analogue udp-4-deoxy-4- fluoro-alpha-d-galactose
25% identity, 93% coverage of query (91.3 bits)
2c20A / A0A6L8PTV5 Crystal structure of udp-glucose 4-epimerase
24% identity, 95% coverage of query (90.9 bits)
2hunA / O58151 Crystal structure of hypothetical protein ph0414 from pyrococcus horikoshii ot3
27% identity, 95% coverage of query (90.9 bits)
3aw9A / A3MUJ4 Structure of udp-galactose 4-epimerase mutant
28% identity, 89% coverage of query (90.1 bits)
1gy8C / Q8T8E9 Trypanosoma brucei udp-galactose 4' epimerase (see paper)
25% identity, 93% coverage of query (89.7 bits)
Or start over
Lawrence Berkeley National Laboratory