Searching for up to 100 curated homologs for GFF1013 FitnessBrowser__Marino:GFF1013 (305 a.a.)
Found high-coverage hits (≥70%) to 29 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YehZ / b2131 glycine betaine ABC transporter periplasmic binding protein OsmF from Escherichia coli K-12 substr. MG1655 (see 4 papers)
osmF / P33362 glycine betaine ABC transporter periplasmic binding protein OsmF from Escherichia coli (strain K12) (see 3 papers)
YEHZ_ECOLI / P33362 Glycine betaine-binding protein YehZ from Escherichia coli (strain K12) (see 2 papers)
55% identity, 92% coverage of query (325 bits)
7s7xA Crystal structure of icytsnfr cytisine sensor precursor binding protein with varenicline bound
34% identity, 90% coverage of query (147 bits)
6v1rA Crystal structure of iachsnfr fluorescent acetylcholine sensor precursor binding protein
34% identity, 90% coverage of query (147 bits)
GLBBP_PSEAE / Q9HXC4 Glycine-betaine-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
30% identity, 96% coverage of query (131 bits)
TC 3.A.1.12.8 / Q93A34 BilEB aka OpuBB protein, component of A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) from Listeria monocytogenes (see paper)
30% identity, 89% coverage of query (127 bits)
EGTUB_LISMO / Q8Y775 Probable ergothioneine transporter EgtUBC from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) (see 2 papers)
30% identity, 89% coverage of query (127 bits)
EGTUB_ENTFA / Q837Z8 Probable ergothioneine transporter EgtUBC from Enterococcus faecalis (strain ATCC 700802 / V583) (see paper)
32% identity, 82% coverage of query (125 bits)
OSMX_SALTY / Q8ZPK2 Osmoprotectant-binding protein OsmX from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.12.14 / Q8ZPK2 Putative periplasmic component, component of OsmU (OsmVWXY) transporter for glycine betaine and choline-O-sulfate uptake. Induced by osmotic stress (0.3M NaCl) (Frossard et al., 2012). Also called OpuCA/CB1/CB2/CC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
30% identity, 97% coverage of query (123 bits)
U5LFB4 ABC-type quaternary amine transporter (subunit 3/3) (EC 7.6.2.9) from Bacillus infantis (see paper)
31% identity, 90% coverage of query (122 bits)
Build an alignment for GFF1013 and 9 homologs with ≥ 30% identity
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EGTU_HELPG / B5Z7I3 Ergothioneine transport permease/ergothioneine binding protein EgtU from Helicobacter pylori (strain G27) (see paper)
28% identity, 90% coverage of query (120 bits)
8dp7A / B6JM49 Structure of helicobacter pylori egtu bound to egt (see paper)
28% identity, 90% coverage of query (120 bits)
7txlA / A0A0H2ZQB9 Crystal structure of egtu solute binding domain from streptococcus pneumoniae d39 in complex with l-ergothioneine (see paper)
28% identity, 91% coverage of query (115 bits)
EGTUB_STAA3 / A0A0H2XK79 Probable ergothioneine transporter EgtUBC from Staphylococcus aureus (strain USA300) (see paper)
28% identity, 90% coverage of query (114 bits)
EGTUB_STRP2 / A0A0H2ZQB9 Ergothioneine transporter EgtUBC from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see paper)
28% identity, 90% coverage of query (112 bits)
TC 3.A.1.12.10 / Q87WH3 OpuC aka PSPTO4577, component of The OpuC transporter selective for glycine betaine > choline, acetylcholine, carnitine and proline betaine (contains tandem cystathionine-β-synthase (CBS) domains in the ABC component of OpuC that are required for osmoregulatory function (Chen and Beattie, 2007)) from Pseudomonas syringae pv. tomato (see paper)
29% identity, 90% coverage of query (110 bits)
TC 3.A.1.12.11 / Q8Q040 Glycine betaine-binding protein, component of The glycine betaine uptake porter, GbpABCD from Methanosarcina mazei (see paper)
29% identity, 90% coverage of query (105 bits)
U5LHK3 ABC-type quaternary amine transporter (subunit 2/3) (EC 7.6.2.9) from Bacillus infantis (see paper)
27% identity, 90% coverage of query (100 bits)
1sw1A / O29280 Crystal structure of prox from archeoglobus fulgidus in complex with proline betaine (see paper)
29% identity, 89% coverage of query (98.2 bits)
OPUBC_BACSU / Q45462 Choline-binding protein from Bacillus subtilis (strain 168) (see 2 papers)
Q45462 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see paper)
TC 3.A.1.12.3 / Q45462 OPBC OpuBC aka PROX, component of Choline porter from Bacillus subtilis (see 3 papers)
25% identity, 86% coverage of query (84.3 bits)
3r6uA Crystal structure of choline binding protein opubc from bacillus subtilis
25% identity, 86% coverage of query (84.0 bits)
6eyhA / Q45462 Structure of a opubc mutant with bound glycine betaine
25% identity, 86% coverage of query (83.6 bits)
6eylA Crystal structure of opubc in complex with carnitine
25% identity, 86% coverage of query (83.6 bits)
5nxyA Crystal structure of opuac from b. Subtilis in complex with arsenobetaine
25% identity, 86% coverage of query (81.6 bits)
OPUCC_BACSU / O32243 Glycine betaine/carnitine/choline-binding protein OpuCC; Osmoprotectant-binding protein from Bacillus subtilis (strain 168) (see 3 papers)
O32243 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see paper)
TC 3.A.1.12.4 / O32243 OPCC aka OpuCC, component of Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate from Bacillus subtilis (see 2 papers)
23% identity, 90% coverage of query (77.4 bits)
OPUCC_LISM4 / G2JZ42 Carnitine transport binding protein OpuCC from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCC_LISMN / Q9KHT7 Carnitine transport binding protein OpuCC from Listeria monocytogenes (see paper)
25% identity, 90% coverage of query (77.0 bits)
3ppoA / O32243 Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of bacillus subtilis abc transporter opuc (see paper)
23% identity, 90% coverage of query (77.0 bits)
3pprA Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of bacillus subtilis abc transporter opuc
23% identity, 87% coverage of query (75.9 bits)
3ppqA Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of bacillus subtilis abc transporter opuc
23% identity, 87% coverage of query (75.9 bits)
COSB_HALS3 / B0R6A8 Chemotactic signal transduction system substrate-binding protein CosB; Compatible solute binding protein from Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) (see paper)
24% identity, 74% coverage of query (49.3 bits)
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Lawrence Berkeley National Laboratory