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Searching for up to 100 curated homologs for GFF1483 FitnessBrowser__Phaeo:GFF1483 (257 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q5KST5 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas fragi (see 3 papers)
1wmbA / Q5KST5 Crystal structure of NAD dependent d-3-hydroxybutylate dehydrogenase (see paper)
BAD86668.1 D(-)-3-hydroxybutyrate dehydrogenase from Pseudomonas fragi (see paper)
    61% identity, 99% coverage of query (311 bits)

5b4tA / D0VWQ0 Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and a substrate d-3- hydroxybutyrate (see paper)
    60% identity, 99% coverage of query (311 bits)

2ztlA Closed conformation of d-3-hydroxybutyrate dehydrogenase complexed with NAD+ and l-3-hydroxybutyrate
    61% identity, 99% coverage of query (311 bits)

3w8dA Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate
    60% identity, 99% coverage of query (311 bits)

3vdrA Crystal structure of d-3-hydroxybutyrate dehydrogenase, prepared in the presence of the substrate d-3-hydroxybutyrate and NAD(+)
    60% identity, 99% coverage of query (311 bits)

3vdqA Crystal structure of alcaligenes faecalis d-3-hydroxybutyrate dehydrogenase in complex with NAD(+) and acetate
    60% identity, 99% coverage of query (311 bits)

5yssB / A0A0D7LY80 Crystal structure of aminocaproic acid cyclase in complex with NAD (+) (see paper)
    58% identity, 99% coverage of query (283 bits)

1x1tA / Q5KST5 Crystal structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas fragi complexed with NAD+ (see paper)
    58% identity, 99% coverage of query (282 bits)

A8R3J3 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Ralstonia pickettii (see paper)
    56% identity, 99% coverage of query (271 bits)

Q9AE70 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas putida (see 2 papers)
    54% identity, 100% coverage of query (259 bits)

Q767A0 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acidovorax sp. (see paper)
    53% identity, 98% coverage of query (258 bits)

2q2qD / Q9AE70 Structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida (see paper)
    54% identity, 99% coverage of query (256 bits)

Q2PEN2 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Ralstonia pickettii (see 2 papers)
    51% identity, 99% coverage of query (247 bits)

A0A1E3M3N6 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acinetobacter baumannii (see paper)
6zzsD / A0A1E3M3N6 Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and 3-oxovalerate (see paper)
    42% identity, 99% coverage of query (197 bits)

6zzqA Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and acetoacetate
    42% identity, 99% coverage of query (197 bits)

Q2PEN3 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Ralstonia pickettii (see 2 papers)
    40% identity, 99% coverage of query (165 bits)

Q5ZT49 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Legionella pneumophila subsp. pneumophila (see paper)
    37% identity, 99% coverage of query (164 bits)

6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
    37% identity, 99% coverage of query (163 bits)

8dt1C / A0A1V2Y0M0 Crystal structure of a putative d-beta-hydroxybutyrate dehydrogenase from burkholderia cenocepacia j2315 in complex with NAD
    41% identity, 98% coverage of query (163 bits)

5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    37% identity, 100% coverage of query (156 bits)

bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
    37% identity, 100% coverage of query (156 bits)

C7RM91 acetoacetyl-CoA reductase (EC 1.1.1.36) from Candidatus Accumulibacter phosphatis (see 2 papers)
    35% identity, 98% coverage of query (155 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    37% identity, 98% coverage of query (153 bits)

Q4FRT2 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Psychrobacter arcticus (see paper)
    37% identity, 98% coverage of query (152 bits)

6zzoC / Q4FRT2 Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from psychrobacter arcticus complexed with NAD+ and acetoacetate (see paper)
    37% identity, 98% coverage of query (152 bits)

6zzpA Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from psychrobacter arcticus complexed with NAD+ and 3-oxovalerate
    37% identity, 98% coverage of query (152 bits)

KDUD_BACSU / P50842 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; EC 1.1.1.127 from Bacillus subtilis (strain 168) (see paper)
    37% identity, 99% coverage of query (148 bits)

phaB / BAC45231.1 3-keto-acyl-CoA reductase from Bacillus sp. INT005 (see paper)
    35% identity, 98% coverage of query (147 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    34% identity, 98% coverage of query (145 bits)

5u9pB / B4EEX4 Crystal structure of a gluconate 5-dehydrogenase from burkholderia cenocepacia j2315 in complex with NADP and tartrate
    38% identity, 100% coverage of query (144 bits)

3uf0A / C5BY10 Crystal structure of a putative NAD(p) dependent gluconate 5- dehydrogenase from beutenbergia cavernae(efi target efi-502044) with bound NADP (low occupancy)
    37% identity, 100% coverage of query (143 bits)

uxaD / Q9WYS2 fructuronate reductase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    35% identity, 99% coverage of query (142 bits)

1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
    35% identity, 99% coverage of query (142 bits)

A0JC04 octanol dehydrogenase (EC 1.1.1.73) from Ogataea wickerhamii (see paper)
    35% identity, 99% coverage of query (139 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    33% identity, 96% coverage of query (139 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    35% identity, 98% coverage of query (139 bits)

Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
    33% identity, 96% coverage of query (139 bits)

4hp8B / A9CEQ9 Crystal structure of a putative 2-deoxy-d-gluconate 3-dehydrogenase from agrobacterium tumefaciens (target efi-506435) with bound NADP
    38% identity, 100% coverage of query (138 bits)

5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    36% identity, 100% coverage of query (138 bits)

FABG_SYNY3 / P73574 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    36% identity, 98% coverage of query (137 bits)

3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
    33% identity, 96% coverage of query (137 bits)

BWI76_RS23705 2-deoxy-D-ribonyl-CoA 3-dehydrogenase from Klebsiella michiganensis M5al
    34% identity, 98% coverage of query (136 bits)

YfeF / b2426 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
ucpA / P37440 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli (strain K12) (see 6 papers)
    36% identity, 98% coverage of query (136 bits)

G0HY85 acetoacetyl-CoA reductase (EC 1.1.1.36) from Haloarcula hispanica (see paper)
    37% identity, 98% coverage of query (136 bits)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    31% identity, 98% coverage of query (136 bits)

dhuD / Q8E370 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase monomer (EC 1.1.1.127) from Streptococcus agalactiae serotype III (strain NEM316) (see paper)
    33% identity, 100% coverage of query (135 bits)

7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
    34% identity, 98% coverage of query (135 bits)

YohE / b2137 putative oxidoreductase YohF from Escherichia coli K-12 substr. MG1655 (see 5 papers)
    35% identity, 97% coverage of query (135 bits)

gno / P50199 D-gluconate 5-dehydrogenase monomer from Gluconobacter oxydans (strain 621H) (see paper)
GNO_GLUOX / P50199 Gluconate 5-dehydrogenase; D-gluconate 5-dehydrogenase (NADP); Gluconate:NADP 5-oxidoreductase; GNO; EC 1.1.1.- from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
    34% identity, 99% coverage of query (135 bits)

2ewmB / Q5P5I4 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 (see paper)
    37% identity, 98% coverage of query (134 bits)

ped / Q5P5I4 1-phenylethanol dehydrogenase subunit (EC 1.1.1.311) from Aromatoleum aromaticum (strain EbN1) (see paper)
PED_AROAE / Q5P5I4 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) (see 2 papers)
Q5P5I4 (S)-1-phenylethanol dehydrogenase (EC 1.1.1.311) from Azoarcus sp. (see paper)
ped / CAI07428.1 (S)-1-Phenylethanol dehydrogenase from Aromatoleum aromaticum EbN1 (see 4 papers)
    37% identity, 98% coverage of query (134 bits)

3o03A Quaternary complex structure of gluconate 5-dehydrogenase from streptococcus suis type 2 (see paper)
    34% identity, 100% coverage of query (134 bits)

A0A5P1RES5 acetoacetyl-CoA reductase (subunit 1/2) (EC 1.1.1.36) from Neptunomonas concharum (see paper)
    31% identity, 98% coverage of query (134 bits)

TR2 / P50163 tropinone reductase (EC 1.1.1.236) from Datura stramonium (see paper)
TRN2_DATST / P50163 Tropinone reductase 2; Tropinone reductase II; TR-II; EC 1.1.1.236 from Datura stramonium (Jimsonweed) (Common thornapple) (see paper)
P50163 tropinone reductase II (EC 1.1.1.236) from Datura stramonium (see 3 papers)
    32% identity, 99% coverage of query (134 bits)

2ae2A / P50163 Tropinone reductase-ii complexed with NADP+ and pseudotropine (see paper)
    32% identity, 99% coverage of query (134 bits)

A0A6B7HD48 tropinone reductase II (EC 1.1.1.236) from Przewalskia tangutica (see paper)
    32% identity, 99% coverage of query (134 bits)

1ipfA Tropinone reductase-ii complexed with NADPH and tropinone
    32% identity, 99% coverage of query (134 bits)

1ipeA Tropinone reductase-ii complexed with NADPH
    32% identity, 99% coverage of query (134 bits)

6oz7A / P33368 Putative oxidoreductase from escherichia coli str. K-12
    35% identity, 97% coverage of query (133 bits)

A0A545BBR2 (1R,2S)-ephedrine 1-dehydrogenase (EC 1.1.1.423) from Arthrobacter sp. TS-15 (see paper)
    34% identity, 100% coverage of query (132 bits)

Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
    31% identity, 96% coverage of query (131 bits)

3ndrA / Q988B7 Crystal structure of tetrameric pyridoxal 4-dehydrogenase from mesorhizobium loti
    37% identity, 98% coverage of query (131 bits)

pldh-t / Q988B7 pyridoxal 4-dehydrogenase subunit (EC 1.1.1.107) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 2 papers)
PLDH_RHILO / Q988B7 Pyridoxal 4-dehydrogenase; tPLDH; EC 1.1.1.107 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see paper)
Q988B7 pyridoxal 4-dehydrogenase (EC 1.1.1.107) from Mesorhizobium loti (see paper)
    37% identity, 98% coverage of query (131 bits)

TRII / CAB52307.1 tropinone reductase II from Solanum tuberosum (see paper)
    32% identity, 99% coverage of query (131 bits)

3rwbA Crystal structure of complex of 4pal (4-pyridoxolactone) and pldh (tetrameric pyridoxal 4-dehydrogenase) from mesorhizobium loti
    37% identity, 98% coverage of query (131 bits)

B2L2W9 tropinone reductase II (EC 1.1.1.236) from Anisodus acutangulus (see paper)
    31% identity, 99% coverage of query (130 bits)

TR2 / Q6KF77 tropinone reductase (EC 1.1.1.236) from Solanum tuberosum (see paper)
    31% identity, 99% coverage of query (129 bits)

YgcW / b2774 putative deoxygluconate dehydrogenase from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    32% identity, 99% coverage of query (129 bits)

Q9WYD3 D-arabinitol 2-dehydrogenase (EC 1.1.1.250) from Thermotoga maritima (see paper)
    35% identity, 99% coverage of query (128 bits)

G3XRE5 gluconate 5-dehydrogenase (EC 1.1.1.69) from Aspergillus niger (see paper)
    34% identity, 99% coverage of query (128 bits)

A0A0M4UR95 L-xylulose reductase (EC 1.1.1.10) from Rhizomucor pusillus (see paper)
    33% identity, 100% coverage of query (127 bits)

kduD / Q05528 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127) from Dickeya dadantii (strain 3937) (see 3 papers)
KDUD_DICD3 / Q05528 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; EC 1.1.1.127 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    33% identity, 100% coverage of query (127 bits)

FABG_RICPR / P50941 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Rickettsia prowazekii (strain Madrid E)
P50941 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Rickettsia prowazekii (see paper)
    30% identity, 98% coverage of query (126 bits)

Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
    32% identity, 98% coverage of query (126 bits)

Q8GR61 D-xylulose reductase (EC 1.1.1.9) from Gluconobacter oxydans (see 2 papers)
    32% identity, 98% coverage of query (126 bits)

1zemA / Q8GR61 Crystal structure of NAD+-bound xylitol dehydrogenase (see paper)
    32% identity, 98% coverage of query (125 bits)

ASTE_ASPOR / Q2UEK6 Short chain dehydrogenase/reductase astE; Astellolide biosynthesis cluster protein E; EC 1.1.-.- from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
    36% identity, 98% coverage of query (125 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    33% identity, 98% coverage of query (125 bits)

A4PB64 sorbose reductase (EC 1.1.1.289) from Gluconobacter frateurii (see paper)
3ai2A / A4PB64 The crystal structure of l-sorbose reductase from gluconobacter frateurii complexed with NADPH (see paper)
    34% identity, 98% coverage of query (125 bits)

TR1 / P50162 tropinone reductase (EC 1.1.1.206) from Datura stramonium (see paper)
TRN1_DATST / P50162 Tropinone reductase 1; Tropine dehydrogenase; Tropinone reductase I; TR-I; EC 1.1.1.206 from Datura stramonium (Jimsonweed) (Common thornapple) (see 2 papers)
P50162 tropinone reductase I (EC 1.1.1.206) from Datura stramonium (see 2 papers)
    32% identity, 99% coverage of query (125 bits)

6qheA / A0A545BBS8 Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
    32% identity, 99% coverage of query (125 bits)

1ae1B / P50162 Tropinone reductase-i complex with NADP (see paper)
    32% identity, 99% coverage of query (125 bits)

Q9LBG2 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum)
    31% identity, 99% coverage of query (124 bits)

1iy8A / Q9LBG2 Crystal structure of levodione reductase (see paper)
    31% identity, 99% coverage of query (124 bits)

4za2D Crystal structure of pectobacterium carotovorum 2-keto-3-deoxy-d- gluconate dehydrogenase complexed with NAD+ (see paper)
    33% identity, 99% coverage of query (124 bits)

3ai3C The crystal structure of l-sorbose reductase from gluconobacter frateurii complexed with NADPH and l-sorbose
    34% identity, 98% coverage of query (123 bits)

3ai3A The crystal structure of l-sorbose reductase from gluconobacter frateurii complexed with NADPH and l-sorbose
    34% identity, 98% coverage of query (123 bits)

4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
    31% identity, 96% coverage of query (123 bits)

4ag3A Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with NADPH at 1.8a resolution
    33% identity, 98% coverage of query (122 bits)

4wecA / A0QVJ7 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
    35% identity, 99% coverage of query (122 bits)

5vt6A / Q3JJT1 Crystal structure of acetoacetyl-coa reductase from burkholderia pseudomallei 1710b complexed with NADP
    30% identity, 96% coverage of query (122 bits)

5h5xC / Q9KYM4 Crystal structure of nadh bound carbonyl reductase from streptomyces coelicolor
    36% identity, 99% coverage of query (122 bits)

4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
    35% identity, 96% coverage of query (122 bits)

4fn4A / Q4J9F2 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius (see paper)
    33% identity, 100% coverage of query (121 bits)

3ay6B / P39485 Crystal structure of bacillus megaterium glucose dehydrogenase 4 a258f mutant in complex with nadh and d-glucose (see paper)
    32% identity, 98% coverage of query (121 bits)

4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
    34% identity, 98% coverage of query (121 bits)

7x5jC / A0A520KTT2 Acp-dependent oxoacyl reductase
    33% identity, 98% coverage of query (120 bits)

4urfB Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1
    33% identity, 100% coverage of query (119 bits)

4urfA Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1
    33% identity, 100% coverage of query (119 bits)

chnA / Q5P8S7 cyclohexanol dehydrogenase from Aromatoleum aromaticum (strain EbN1) (see paper)
4ureB / Q5P8S7 Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1 (see paper)
    33% identity, 100% coverage of query (119 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory