Searching for up to 100 curated homologs for GFF1582 FitnessBrowser__Phaeo:GFF1582 (353 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

Removed hits that are identical to the query, leaving 8

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DvMF_0476 vitamin B12-dependent methionine synthase without a reactivation domain (EC 2.1.1.13) from Desulfovibrio vulgaris Miyazaki F
    34% identity, 82% coverage of query (152 bits)

DVU1585 Methionine synthase (cobalamin-dependent) (EC 2.1.1.13) from Desulfovibrio vulgaris Hildenborough JW710
    37% identity, 71% coverage of query (151 bits)

acsE / Q46389 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase subunit (EC 2.1.1.258) from Moorella thermoacetica (see 4 papers)
ACSE_MOOTH / Q46389 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase; 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase; MeTr; EC 2.1.1.258 from Moorella thermoacetica (Clostridium thermoaceticum) (see 3 papers)
Q46389 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase (EC 2.1.1.258) from Moorella thermoacetica (see 3 papers)
4djdA / Q46389 Crystal structure of folate-free corrinoid iron-sulfur protein (cfesp) in complex with its methyltransferase (metr) (see paper)
    31% identity, 77% coverage of query (126 bits)

4djfA Crystal structure of folate-bound corrinoid iron-sulfur protein (cfesp) in complex with its methyltransferase (metr), co-crystallized with folate and ti(iii) citrate reductant
    31% identity, 77% coverage of query (126 bits)

4djeA Crystal structure of folate-bound corrinoid iron-sulfur protein (cfesp) in complex with its methyltransferase (metr), co-crystallized with folate
    31% identity, 77% coverage of query (126 bits)

2e7fA 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase complexed with methyltetrahydrofolate to 2.2 angsrom resolution
    31% identity, 77% coverage of query (126 bits)

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Build an alignment for GFF1582 and 6 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

metH / Q8NQD1 cobalamin-dependent methionine synthase (EC 2.1.1.13) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
    28% identity, 77% coverage of query (104 bits)

MetH / b4019 cobalamin-dependent methionine synthase (EC 2.1.1.13) from Escherichia coli K-12 substr. MG1655 (see 60 papers)
metH / P13009 cobalamin-dependent methionine synthase (EC 2.1.1.13) from Escherichia coli (strain K12) (see 58 papers)
METH_ECOLI / P13009 Methionine synthase; 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12-dependent; MS; EC 2.1.1.13 from Escherichia coli (strain K12) (see 4 papers)
metH methionine synthase; EC 2.1.1.13 from Escherichia coli K12 (see 15 papers)
    27% identity, 74% coverage of query (84.3 bits)

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