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Searching for up to 100 curated homologs for GFF1615 FitnessBrowser__Phaeo:GFF1615 (310 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

arcA / P14012 arginase subunit (EC 3.5.3.1) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see 3 papers)
arc / CAA82964.1 arginase from Agrobacterium tumefaciens (see 3 papers)
    58% identity, 98% coverage of query (346 bits)

Ac3H11_701 Arginase (EC 3.5.3.1) from Acidovorax sp. GW101-3H11
    44% identity, 97% coverage of query (215 bits)

N515DRAFT_0348 Arginase (EC 3.5.3.1) from Dyella japonica UNC79MFTsu3.2
    41% identity, 95% coverage of query (201 bits)

2ef5A / Q5SI78 Crystal structure of the arginase from thermus thermophilus
    42% identity, 95% coverage of query (194 bits)

argI / P39138 arginase (EC 3.5.3.1) from Bacillus subtilis (strain 168) (see 3 papers)
ARGI_BACSU / P39138 Arginase; EC 3.5.3.1 from Bacillus subtilis (strain 168) (see 2 papers)
P39138 arginase (EC 3.5.3.1) from Bacillus subtilis (see paper)
    37% identity, 96% coverage of query (192 bits)

ARG2 / P78540 Arginase-2, mitochondrial (EC 3.5.3.1) from Homo sapiens (see 8 papers)
ARGI2_HUMAN / P78540 Arginase-2, mitochondrial; Arginase II; Kidney-type arginase; Non-hepatic arginase; Type II arginase; EC 3.5.3.1 from Homo sapiens (Human) (see 7 papers)
P78540 arginase (EC 3.5.3.1) from Homo sapiens (see 5 papers)
    38% identity, 96% coverage of query (191 bits)

6ss2AAA / P78540 of arginase-2 in complex with the inhibitory human antigen-binding fragment fab c0021158' (see paper)
    39% identity, 94% coverage of query (190 bits)

6q39A Complex of arginase 2 with example 49
    39% identity, 94% coverage of query (190 bits)

6q37A Complex of arginase 2 with example 23
    39% identity, 94% coverage of query (190 bits)

4ixvA Crystal structure of human arginase-2 complexed with inhibitor 2d: {(5r)-5-amino-5-carboxy-5-[1-(4-chlorobenzyl)piperidin-4- yl]pentyl}(trihydroxy)borate(1-)
    39% identity, 94% coverage of query (190 bits)

4ixuA Crystal structure of human arginase-2 complexed with inhibitor 11d: {(5r)-5-amino-5-carboxy-5-[(3-endo)-8-(3,4-dichlorobenzyl)-8- azabicyclo[3.2.1]oct-3-yl]pentyl}(trihydroxy)borate(1-)
    39% identity, 94% coverage of query (190 bits)

4ie3A Crystal structure of human arginase-2 complexed with inhbitor 1o
    39% identity, 94% coverage of query (190 bits)

4ie2A Crystal structure of human arginase-2 complexed with inhibitor 1h
    39% identity, 94% coverage of query (190 bits)

4i06A Crystal structure of human arginase-2 complexed with inhibitor 14
    39% identity, 94% coverage of query (190 bits)

4hzeA Crystal structure of human arginase-2 complexed with inhibitor 9
    39% identity, 94% coverage of query (190 bits)

1pq3A Human arginase ii: crystal structure and physiological role in male and female sexual arousal
    39% identity, 94% coverage of query (190 bits)

A4IJM8 arginase (EC 3.5.3.1) from Geobacillus thermodenitrificans (see paper)
    38% identity, 95% coverage of query (189 bits)

6nfpA / P39138 1.7 angstrom resolution crystal structure of arginase from bacillus subtilis subsp. Subtilis str. 168
    38% identity, 96% coverage of query (189 bits)

6dktA Crystal structure of arginase from bacillus subtilis
    38% identity, 96% coverage of query (188 bits)

6nfpD 1.7 angstrom resolution crystal structure of arginase from bacillus subtilis subsp. Subtilis str. 168
    38% identity, 96% coverage of query (187 bits)

ARGI2_MOUSE / O08691 Arginase-2, mitochondrial; Arginase II; Kidney-type arginase; Non-hepatic arginase; Type II arginase; EC 3.5.3.1 from Mus musculus (Mouse) (see 6 papers)
    37% identity, 94% coverage of query (183 bits)

ARGI_BACCD / P53608 Arginase; EC 3.5.3.1 from Bacillus caldovelox (see paper)
P53608 arginase (EC 3.5.3.1) from [Bacillus] caldovelox (see paper)
1cevA / P53608 Arginase from bacillus caldovelox, native structure at ph 5.6 (see paper)
    37% identity, 96% coverage of query (183 bits)

5cevA Arginase from bacillus caldevelox, l-lysine complex
    37% identity, 96% coverage of query (183 bits)

4cevA Arginase from bacillus caldevelox, l-ornithine complex
    37% identity, 96% coverage of query (183 bits)

3cevA Arginase from bacillus caldevelox, complexed with l-arginine
    37% identity, 96% coverage of query (183 bits)

2cevB Arginase from bacillus caldevelox, native structure at ph 8.5
    37% identity, 96% coverage of query (183 bits)

O08701 arginase (EC 3.5.3.1) from Rattus norvegicus (see paper)
    37% identity, 94% coverage of query (177 bits)

Q4VK78 arginase (EC 3.5.3.1) from Oryctolagus cuniculus (see paper)
    36% identity, 96% coverage of query (176 bits)

U6BQJ3 arginase (EC 3.5.3.1) from Heteropneustes fossilis (see 2 papers)
    38% identity, 95% coverage of query (175 bits)

A0A0D5ZYA4 arginase (EC 3.5.3.1) from Heteropneustes fossilis (see paper)
    39% identity, 94% coverage of query (174 bits)

6nbkA / W8YSI5 Crystal structure of arginase from bacillus cereus
    38% identity, 95% coverage of query (172 bits)

Q4A3J0 arginase (EC 3.5.3.1) from Cyprinus carpio (see paper)
    39% identity, 95% coverage of query (169 bits)

A0A1S3R1W2 arginase (EC 3.5.3.1) from Salmo salar (see paper)
    38% identity, 95% coverage of query (169 bits)

A0A060YSI8 arginase (EC 3.5.3.1) from Oncorhynchus mykiss (see paper)
    39% identity, 95% coverage of query (168 bits)

C0H9C1 arginase (EC 3.5.3.1) from Salmo salar (see paper)
    38% identity, 95% coverage of query (168 bits)

Q4A4U9 arginase (EC 3.5.3.1) from Cyprinus carpio (see paper)
    39% identity, 95% coverage of query (168 bits)

Q4A3J1 arginase (EC 3.5.3.1) from Cyprinus carpio (see paper)
    39% identity, 95% coverage of query (167 bits)

6dktE / P39138 Crystal structure of arginase from bacillus subtilis
    36% identity, 96% coverage of query (166 bits)

A0A1P8DAN3 arginase (EC 3.5.3.1) from Oncorhynchus mykiss (see paper)
    38% identity, 95% coverage of query (166 bits)

ARG1 / P05089 Arginase-1 (EC 3.5.3.1) from Homo sapiens (see 7 papers)
ARGI1_HUMAN / P05089 Arginase-1; Liver-type arginase; Type I arginase; EC 3.5.3.1 from Homo sapiens (Human) (see 15 papers)
P05089 arginase (EC 3.5.3.1) from Homo sapiens (see 12 papers)
    36% identity, 96% coverage of query (166 bits)

Q4A3J2 arginase (EC 3.5.3.1) from Cyprinus carpio (see paper)
    37% identity, 94% coverage of query (165 bits)

A0A1P8DAM2 arginase (EC 3.5.3.1) from Oncorhynchus mykiss (see paper)
    37% identity, 94% coverage of query (165 bits)

B5XDG2 arginase (EC 3.5.3.1) from Salmo salar (see paper)
    37% identity, 94% coverage of query (164 bits)

4gszA Crystal structure of the zn2+5-human arginase i-abh complex
    37% identity, 95% coverage of query (164 bits)

4fciA Crystal structure of the mn2+2-human arginase i-agpa complex
    37% identity, 95% coverage of query (164 bits)

3mfwA Crystal structure of human arginase i in complex with l-2- aminohistidine and sulphate
    37% identity, 95% coverage of query (164 bits)

3gn0A Crystal structure of human arginase i in complex with difluoromethylornithine (dfmo)
    37% identity, 95% coverage of query (164 bits)

3gmzA Crystal of human arginase in complex with l-ornithine. Resolution 1.43 a.
    37% identity, 95% coverage of query (164 bits)

8e5nA Structure of arg1 complex with pyrrolidine-based non-boronic acid inhibitor 10
    37% identity, 95% coverage of query (164 bits)

8e5mA Structure of arg1 complex with pyrrolidine-based non-boronic acid inhibitor 6
    37% identity, 95% coverage of query (164 bits)

7klmA Human arginase1 complexed with inhibitor compound 24a
    37% identity, 95% coverage of query (164 bits)

7kllA Human arginase1 complexed with inhibitor compound 18
    37% identity, 95% coverage of query (164 bits)

7klkA Human arginase1 complexed with inhibitor compound 3a
    37% identity, 95% coverage of query (164 bits)

7k4kA Human arginase 1 in complex with compound 52.
    37% identity, 95% coverage of query (164 bits)

7k4jA Human arginase 1 in complex with compound 51.
    37% identity, 95% coverage of query (164 bits)

7k4iA Human arginase 1 in complex with compound 06.
    37% identity, 95% coverage of query (164 bits)

6v7eA Human arginase1 complexed with bicyclic inhibitor compound 12
    37% identity, 95% coverage of query (164 bits)

6v7cA Human arginase1 complexed with bicyclic inhibitor compound 3
    37% identity, 95% coverage of query (164 bits)

8aupA Structure of harg1 with a novel inhibitor.
    37% identity, 95% coverage of query (164 bits)

4ie1A Crystal structure of human arginase-1 complexed with inhibitor 1h
    37% identity, 95% coverage of query (164 bits)

4hxqA Crystal structure of human arginase-1 complexed with inhibitor 14
    37% identity, 95% coverage of query (164 bits)

4hwwA Crystal structure of human arginase-1 complexed with inhibitor 9
    37% identity, 95% coverage of query (164 bits)

2aebA Crystal structure of human arginase i at 1.29 a resolution and exploration of inhibition in immune response.
    37% identity, 95% coverage of query (164 bits)

1wvaA Crystal structure of human arginase i from twinned crystal
    37% identity, 95% coverage of query (164 bits)

7k4hA Human arginase 1 in complex with compound 04.
    37% identity, 95% coverage of query (164 bits)

6v7fA Human arginase1 complexed with bicyclic inhibitor compound 13
    37% identity, 95% coverage of query (164 bits)

6v7dA Human arginase1 complexed with bicyclic inhibitor compound 10
    37% identity, 95% coverage of query (164 bits)

6qafA Crystal structure of human arginase-1 at ph 9.0 in complex with cb- 1158/incb001158
    37% identity, 95% coverage of query (164 bits)

6q92A Crystal structure of human arginase-1 at ph 7.0 in complex with abh
    37% identity, 95% coverage of query (164 bits)

7k4gE / P05089 Human arginase 1 in complex with compound 01. (see paper)
    37% identity, 95% coverage of query (163 bits)

ARGI1_RAT / P07824 Arginase-1; Liver-type arginase; Type I arginase; EC 3.5.3.1 from Rattus norvegicus (Rat) (see 6 papers)
P07824 arginase (EC 3.5.3.1) from Rattus norvegicus (see 5 papers)
    35% identity, 97% coverage of query (163 bits)

1hqfA / P07824 Crystal structure of the binuclear manganese metalloenzyme arginase complexed with n-hydroxy-l-arginine (see paper)
    36% identity, 94% coverage of query (162 bits)

1t4tA Arginase-dinor-noha complex
    36% identity, 94% coverage of query (162 bits)

1t4sA Arginase-l-valine complex
    36% identity, 94% coverage of query (162 bits)

1t4rA Arginase-descarboxy-nor-noha complex
    36% identity, 94% coverage of query (162 bits)

1t4pA Arginase-dehydro-abh complex
    36% identity, 94% coverage of query (162 bits)

1r1oA Amino acid sulfonamides as transition-state analogue inhibitors of arginase
    36% identity, 94% coverage of query (162 bits)

1hqhA Crystal structure of the binuclear manganese metalloenzyme arginase complexed with nor-n-hydroxy-l-arginine
    36% identity, 94% coverage of query (162 bits)

1hq5A Crystal structure of the binuclear manganese metalloenzyme arginase complexed with s-(2-boronoethyl)-l-cysteine, an l-arginine analogue
    36% identity, 94% coverage of query (162 bits)

1d3vA Crystal structure of the binuclear manganese metalloenzyme arginase complexed with 2(s)-amino-6-boronohexanoic acid, an l-arginine analog
    36% identity, 94% coverage of query (162 bits)

3th7A Crystal structure of unliganded co2+2-hai (ph 7.0)
    36% identity, 95% coverage of query (162 bits)

3skkA Crystal structure of human arginase i in complex with the inhibitor fabh, resolution 1.70 a, twinned structure
    36% identity, 95% coverage of query (162 bits)

3mjlA Crystal structure of human arginase i in complex with 2- aminoimidazole. Resolution 1.90 a.
    36% identity, 95% coverage of query (162 bits)

3sjtA Crystal structure of human arginase i in complex with the inhibitor me-abh, resolution 1.60 a, twinned structure
    36% identity, 95% coverage of query (162 bits)

3mfvA Crystal structure of human arginase i in complex with 2- aminohomohistidine
    36% identity, 95% coverage of query (162 bits)

3lp7A Crystal structure of human arginase i in complex with inhibitor n(omega)-hydroxy-l-arginine (noha), 2.04a resolution
    36% identity, 95% coverage of query (162 bits)

3lp4A Crystal structure of human arginase i in complex with l-lysine, 1.90a resolution.
    36% identity, 95% coverage of query (162 bits)

3kv2A High resolution structure of human arginase i in complex with the strong inhibitor n(omega)-hydroxy-nor-l-arginine (nor-noha)
    36% identity, 95% coverage of query (162 bits)

3f80A (S)-2-amino-6-nitrohexanoic acid binds to human arginase i through multiple nitro-metal coordination interactions in the binuclear manganese cluster. Resolution 1.60 a.
    36% identity, 95% coverage of query (162 bits)

3dj8A Synthesis of (2s)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase i
    36% identity, 95% coverage of query (162 bits)

2phoA Crystal structure of human arginase i complexed with thiosemicarbazide at 1.95 resolution
    36% identity, 95% coverage of query (162 bits)

I7KJN7 arginase (EC 3.5.3.1) from Oncorhynchus mykiss (see paper)
    36% identity, 94% coverage of query (161 bits)

A0A1S3NED8 arginase (EC 3.5.3.1) from Salmo salar (see paper)
    36% identity, 94% coverage of query (160 bits)

ARGI1_MOUSE / Q61176 Arginase-1; Liver-type arginase; Type I arginase; EC 3.5.3.1 from Mus musculus (Mouse) (see 10 papers)
Q61176 arginase (EC 3.5.3.1) from Mus musculus (see paper)
    35% identity, 97% coverage of query (160 bits)

1t5gA Arginase-f2-l-arginine complex
    36% identity, 95% coverage of query (160 bits)

1t5fA Arginase i-aoh complex
    36% identity, 95% coverage of query (160 bits)

1hqgA Crystal structure of the h141c arginase variant complexed with products ornithine and urea
    36% identity, 94% coverage of query (159 bits)

ARGI_KLULA / Q6CLS8 Arginase; EC 3.5.3.1 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) (see paper)
    34% identity, 87% coverage of query (147 bits)

car1 / RF|NP_595133.1 arginase Car1; EC 3.5.3.1 from Schizosaccharomyces pombe (see 3 papers)
    33% identity, 93% coverage of query (146 bits)

3mmrA / Q8I384 Structure of plasmodium falciparum arginase in complex with abh (see paper)
    30% identity, 91% coverage of query (145 bits)

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Build an alignment for GFF1615 and 100 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory