Searching for up to 100 curated homologs for GFF1627 FitnessBrowser__Marino:GFF1627 (348 a.a.)
Found high-coverage hits (≥70%) to 29 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
XDH2_HALVD / D4GP30 D-xylose 1-dehydrogenase (NADP(+)) 2; XDH 2; EC 1.1.1.179 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GP30 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179) from Haloferax volcanii (see paper)
31% identity, 97% coverage of query (139 bits)
KIJDR_ACTKI / B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; 3-ketoreductase; NADPH-dependent C3-ketoreductase; EC 1.1.1.384 from Actinomadura kijaniata (see paper)
B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Actinomadura kijaniata (see paper)
30% identity, 94% coverage of query (114 bits)
Build an alignment for GFF1627 and 2 homologs with ≥ 30% identity
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3rc1A / B3TMR8 Crystal structure of kijd10, a 3-ketoreductase from actinomadura kijaniata incomplex with NADP and tdp-benzene (see paper)
29% identity, 92% coverage of query (114 bits)
slgS4 / CBA11563.1 NDP-hexose-3-ketoreductase from Streptomyces lydicus (see paper)
30% identity, 90% coverage of query (112 bits)
GRA26_STRVN / Q9ZA33 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; Gra-orf26 protein; dTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase; EC 1.1.1.384 from Streptomyces violaceoruber
30% identity, 73% coverage of query (101 bits)
oleW / Q9RR32 dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase (EC 1.1.1.384) from Streptomyces antibioticus (see paper)
OLEW_STRAT / Q9RR32 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; dTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase; EC 1.1.1.384 from Streptomyces antibioticus (see paper)
Q9RR32 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Streptomyces antibioticus (see paper)
28% identity, 74% coverage of query (92.0 bits)
Q9DBB8 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Mus musculus (see paper)
25% identity, 73% coverage of query (82.8 bits)
DHDH_PIG / Q9TV69 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Sus2DD; EC 1.3.1.20; EC 1.1.1.179 from Sus scrofa (Pig) (see 3 papers)
25% identity, 72% coverage of query (75.9 bits)
jadP / Q939Q8 dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose reductase (EC 1.1.1.384) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
Q939Q8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Streptomyces venezuelae (see paper)
29% identity, 71% coverage of query (68.9 bits)
E1U888 inositol 2-dehydrogenase (EC 1.1.1.18) from Lacticaseibacillus casei (see paper)
25% identity, 73% coverage of query (68.6 bits)
4n54A / A0A0J9X1Y7 Crystal structure of scyllo-inositol dehydrogenase from lactobacillus casei with bound cofactor NAD(h) and scyllo-inositol
25% identity, 72% coverage of query (66.6 bits)
6o15A / P39353 Crystal structure of a putative oxidoreductase yjhc from escherichia coli in complex with NAD(h) (see paper)
25% identity, 72% coverage of query (66.6 bits)
1rydA Crystal structure of glucose-fructose oxidoreductase from zymomonas mobilis
23% identity, 74% coverage of query (66.6 bits)
NanY / b4280 KpLE2 phage-like element; 2,7-anhydro-N-acetylneuraminate hydratase from Escherichia coli K-12 substr. MG1655 (see 4 papers)
nanY / P39353 KpLE2 phage-like element; 2,7-anhydro-N-acetylneuraminate hydratase from Escherichia coli (strain K12) (see 6 papers)
YJHC_ECOLI / P39353 Uncharacterized oxidoreductase YjhC; EC 1.-.-.- from Escherichia coli (strain K12) (see paper)
25% identity, 72% coverage of query (66.2 bits)
1h6dA / Q07982 Oxidized precursor form of glucose-fructose oxidoreductase from zymomonas mobilis complexed with glycerol (see paper)
23% identity, 74% coverage of query (66.2 bits)
gfo / Q07982 glucose-fructose oxidoreductase (EC 1.1.99.28) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
Q07982 glucose-fructose oxidoreductase (EC 1.1.99.28) from Zymomonas mobilis (see 4 papers)
23% identity, 74% coverage of query (65.9 bits)
Q93PS4 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase (EC 1.1.1.312) from Comamonas testosteroni (see paper)
24% identity, 75% coverage of query (63.5 bits)
proD / Q75T27 α-hydroxy-γ-carboxymuconate ε-semialdehyde dehydrogenase subunit (EC 1.1.1.312) from Pseudomonas straminea (see 2 papers)
proD / BAD04059.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Pseudomonas straminea (see paper)
23% identity, 75% coverage of query (62.8 bits)
6z3cAAA / A0A2N5NNS3 6z3cAAA (see paper)
27% identity, 73% coverage of query (61.2 bits)
3ceaA / F9ULF9 Crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from lactobacillus plantarum at 2.40 a resolution
27% identity, 70% coverage of query (58.9 bits)
iolG / Q9WYP5 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
IOLG_THEMA / Q9WYP5 Myo-inositol 2-dehydrogenase; EC 1.1.1.18 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WYP5 D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Thermotoga maritima (see paper)
23% identity, 73% coverage of query (55.8 bits)
ligC / Q9KWL3 LigC (EC 1.1.1.312) from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see paper)
LIGC_SPHSK / Q9KWL3 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase; CHMS dehydrogenase; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase; EC 1.1.1.312 from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see paper)
ligC / BAA97119.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Sphingomonas paucimobilis (see 3 papers)
ligC / BAB88744.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Sphingomonas paucimobilis (see 5 papers)
23% identity, 74% coverage of query (55.5 bits)
4l8vA / P26935 Crystal structure of a12k/d35s mutant myo-inositol dehydrogenase from bacillus subtilis with bound cofactor NADP (see paper)
24% identity, 72% coverage of query (48.9 bits)
xacA / D4GP29 D-xylose dehydrogenase subunit (EC 1.1.1.424) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 4 papers)
XDH1_HALVD / D4GP29 D-xylose 1-dehydrogenase [NADP(+)] 1; XDH 1; EC 1.1.1.424 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 3 papers)
D4GP29 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) (EC 1.1.1.424) from Haloferax volcanii (see 2 papers)
22% identity, 93% coverage of query (46.2 bits)
iolG / P26935 inositol 2-dehydrogenase monomer (EC 1.1.1.18; EC 1.1.1.369) from Bacillus subtilis (strain 168) (see 5 papers)
IOLG_BACSU / P26935 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; MI 2-dehydrogenase/DCI 3-dehydrogenase; EC 1.1.1.18; EC 1.1.1.369 from Bacillus subtilis (strain 168) (see 3 papers)
P26935 inositol 2-dehydrogenase (EC 1.1.1.18); D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Bacillus subtilis (see 7 papers)
23% identity, 72% coverage of query (46.2 bits)
3nt5A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor and product inosose
23% identity, 72% coverage of query (46.2 bits)
3nt4A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor nadh and inositol
23% identity, 72% coverage of query (46.2 bits)
3nt2B Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
23% identity, 72% coverage of query (46.2 bits)
3nt2A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
23% identity, 72% coverage of query (46.2 bits)
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Lawrence Berkeley National Laboratory