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Searching for up to 100 curated homologs for GFF1675 FitnessBrowser__WCS417:GFF1675 (448 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5uxmA / Q9I000 Type ii dah7ps from pseudomonas aeruginosa with trp bound (see paper)
    88% identity, 99% coverage of query (840 bits)

5uxnA Type ii dah7ps from pseudomonas aeruginosa with tyr bound
    88% identity, 99% coverage of query (840 bits)

P29976 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Arabidopsis thaliana (see paper)
    60% identity, 98% coverage of query (584 bits)

AROG2_PETHY / A0A067XGX8 Phospho-2-dehydro-3-deoxyheptonate aldolase 2, chloroplastic; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 2; DAHP synthase 2; PhDAHP2; Phospho-2-keto-3-deoxyheptonate aldolase 2; EC 2.5.1.54 from Petunia hybrida (Petunia) (see paper)
    60% identity, 98% coverage of query (568 bits)

A0A0D5ZBC4 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Gossypium hirsutum (see paper)
    60% identity, 98% coverage of query (563 bits)

AROG1_PETHY / A0A067XH53 Phospho-2-dehydro-3-deoxyheptonate aldolase 1, chloroplastic; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1; DAHP synthase 1; PhDAHP1; Phospho-2-keto-3-deoxyheptonate aldolase 1; EC 2.5.1.54 from Petunia hybrida (Petunia) (see 2 papers)
    59% identity, 99% coverage of query (562 bits)

O68903 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Actinosynnema pretiosum subsp. auranticum (see paper)
    51% identity, 96% coverage of query (461 bits)

AROG_MYCTU / O53512 Phospho-2-dehydro-3-deoxyheptonate aldolase AroG; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; EC 2.5.1.54 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
O53512 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Mycobacterium tuberculosis (see 3 papers)
    49% identity, 98% coverage of query (444 bits)

3nv8B / O53512 The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol pyruvate and manganese (thesit-free) (see paper)
    49% identity, 98% coverage of query (444 bits)

2ypqA 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound
    49% identity, 98% coverage of query (444 bits)

2yppA 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules
    49% identity, 98% coverage of query (444 bits)

5e40A 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis with d-tyrosine bound in the phenylalanine binding site
    49% identity, 98% coverage of query (444 bits)

5e2lA 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis in complex with d-phenylalanine
    49% identity, 98% coverage of query (444 bits)

3pfpA Structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis in complex with an active site inhibitor
    49% identity, 98% coverage of query (444 bits)

5e5gA 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase with d-tryptophan bound in the tryptophan and phenylalanine binding sites
    49% identity, 98% coverage of query (444 bits)

2ypoA 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase with phenylalanine bound in only one site
    49% identity, 98% coverage of query (444 bits)

5hudD / Q8NNL5 Non-covalent complex of and dahp synthase and chorismate mutase from corynebacterium glutamicum with bound transition state analog (see paper)
    49% identity, 96% coverage of query (443 bits)

5hucA Dahp synthase from corynebacterium glutamicum
    49% identity, 96% coverage of query (443 bits)

2b7oA The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis
    48% identity, 98% coverage of query (419 bits)

3nueB The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis complexed with tryptophan
    47% identity, 98% coverage of query (401 bits)

G3XCJ9 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Pseudomonas aeruginosa (see paper)
    39% identity, 93% coverage of query (269 bits)

6bmcA / G3XCJ9 The structure of a dimeric type ii dah7ps associated with pyocyanin biosynthesis in pseudomonas aeruginosa (see paper)
    39% identity, 93% coverage of query (264 bits)

Build an alignment

Build an alignment for GFF1675 and 22 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory