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Searching for up to 100 curated homologs for GFF1728 FitnessBrowser__Marino:GFF1728 (480 a.a.)

Found high-coverage hits (≥70%) to 37 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YjiR / b4340 fused putative DNA-binding transcriptional regulator/putative aminotransferase YjiR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yjiR / RF|NP_418760 uncharacterized HTH-type transcriptional regulator yjiR from Escherichia coli K12 (see 2 papers)
    36% identity, 96% coverage of query (300 bits)

DVU0030 / VIMSS7650531 DVU0030 regulator of Amino acid transport from Desulfovibrio magneticus RS-1
    34% identity, 96% coverage of query (266 bits)

DVU0030 / VIMSS8508254 DVU0030 regulator of Amino acid transport from Desulfovibrio salexigens DSM 2638
    32% identity, 97% coverage of query (263 bits)

YdcR / b1439 fused putative DNA-binding transcriptional regulator/putative aminotransferase YdcR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydcR / MB|P77730 uncharacterized HTH-type transcriptional regulator ydcR from Escherichia coli K12 (see 3 papers)
    34% identity, 96% coverage of query (262 bits)

DVU0030 / VIMSS408289 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris Hildenborough
    34% identity, 97% coverage of query (261 bits)

DVU0030 / VIMSS8501445 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris str. Miyazaki F
    34% identity, 95% coverage of query (255 bits)

DVU0030 / VIMSS7454265 DVU0030 regulator of Amino acid transport from Desulfohalobium retbaense DSM 5692
    33% identity, 96% coverage of query (246 bits)

DVU0030 / VIMSS7533539 DVU0030 regulator of Amino acid transport from Desulfomicrobium baculatum DSM 4028
    33% identity, 96% coverage of query (246 bits)

DVU0030 / VIMSS393253 DVU0030 regulator of Amino acid transport from Desulfovibrio desulfuricans G20
    31% identity, 96% coverage of query (226 bits)

YdfD/YisV / VIMSS6924547 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Paenibacillus sp. JDR-2
    31% identity, 92% coverage of query (177 bits)

A0A060PQX5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermococcus sp. (see paper)
    31% identity, 77% coverage of query (156 bits)

ARAT1_THELN / H3ZPL1 Aromatic-amino-acid aminotransferase 1; ARAT-I; AROAT; EC 2.6.1.57 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
    30% identity, 77% coverage of query (155 bits)

Build an alignment

Build an alignment for GFF1728 and 12 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

NORG_STAA8 / Q2G1P1 HTH-type transcriptional regulator NorG from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    23% identity, 90% coverage of query (152 bits)

YdfD/YisV / VIMSS822665 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus clausii KSM-K16
    26% identity, 94% coverage of query (150 bits)

YdfD/YisV / VIMSS63013 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus halodurans C-125
    26% identity, 96% coverage of query (145 bits)

AZOBR_RS06555 Branched-chain-amino-acid transaminase (EC 2.6.1.42) from Azospirillum brasilense Sp245
    32% identity, 71% coverage of query (139 bits)

TAUR_RHOCB / D5AKX9 HTH-type transcriptional regulator TauR from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
    28% identity, 92% coverage of query (123 bits)

PdxR / VIMSS295699 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus mutans UA159
    24% identity, 85% coverage of query (120 bits)

PdxR / VIMSS101492 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus pyogenes M1 GAS
    29% identity, 80% coverage of query (117 bits)

PdxR / VIMSS10395811 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus gallolyticus UCN34
    24% identity, 84% coverage of query (113 bits)

PdxR / VIMSS3789276 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus gordonii str. Challis substr. CH1
    26% identity, 74% coverage of query (112 bits)

PdxR / VIMSS5804477 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus equi subsp. zooepidemicus MGCS10565
    27% identity, 79% coverage of query (110 bits)

7zn5B / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the closed conformation, c2 symmetry. (see paper)
    24% identity, 89% coverage of query (102 bits)

7zlaB / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the half-closed conformation (see paper)
    24% identity, 89% coverage of query (101 bits)

Desal_3745 / VIMSS8508801 Desal_3745 regulator of Metabolite transport from Desulfovibrio salexigens DSM 2638
    24% identity, 94% coverage of query (92.8 bits)

GABR_BACSU / P94426 HTH-type transcriptional regulatory protein GabR from Bacillus subtilis (strain 168) (see 2 papers)
    26% identity, 83% coverage of query (88.6 bits)

PDXR_CORGL / Q8NS92 HTH-type pyridoxine biosynthesis transcriptional regulator PdxR from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
    27% identity, 75% coverage of query (86.7 bits)

AAPAT_THET8 / Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 5 papers)
Q56232 aspartate-prephenate aminotransferase (EC 2.6.1.78) from Thermus thermophilus (see paper)
aspC / RF|YP_143312.1 aspartate transaminase; EC 2.6.1.1 from Thermus thermophilus HB8 (see 2 papers)
    25% identity, 70% coverage of query (66.2 bits)

1bkgA Aspartate aminotransferase from thermus thermophilus with maleate
    25% identity, 70% coverage of query (66.2 bits)

1bjwA Aspartate aminotransferase from thermus thermophilus
    25% identity, 70% coverage of query (66.2 bits)

1b5oA / Q56232 Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
    25% identity, 70% coverage of query (65.5 bits)

1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate
    25% identity, 70% coverage of query (65.1 bits)

1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan
    25% identity, 70% coverage of query (65.1 bits)

1o4sB / Q9X0Y2 Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
    23% identity, 74% coverage of query (63.5 bits)

6l1lB / P39643 Apo-bacf structure from bacillus subtillis (see paper)
    24% identity, 71% coverage of query (61.2 bits)

6l1oB Product bound bacf structure from bacillus subtillis
    24% identity, 71% coverage of query (61.2 bits)

6l1nA Substrate bound bacf structure from bacillus subtillis
    24% identity, 71% coverage of query (61.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory