Searching for up to 100 curated homologs for GFF1784 FitnessBrowser__psRCH2:GFF1784 (313 a.a.)
Found high-coverage hits (≥70%) to 76 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
wbpV / Q9RHC9 UDP-N-acetyl-α-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Pseudomonas aeruginosa (see paper)
52% identity, 98% coverage of query (323 bits)
wreQ / Q6TP29 UDP-N-acetyl-α-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Rhizobium etli (see 2 papers)
Q6TP29 UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Rhizobium etli (see paper)
51% identity, 99% coverage of query (307 bits)
ORF35x7 / CAA69124.1 ORF35x7 from Vibrio cholerae (see paper)
50% identity, 98% coverage of query (295 bits)
wbiG / GI|3135686 putative epimerase/dehydratase WbiG from Burkholderia pseudomallei (see paper)
42% identity, 97% coverage of query (236 bits)
wbpK / P72144 UDP-N-acetyl-α-D-fucosamine dehydrogenase from Pseudomonas aeruginosa (see 2 papers)
40% identity, 97% coverage of query (219 bits)
Build an alignment for GFF1784 and 5 homologs with ≥ 30% identity
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gnu / Q8X7P7 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase (EC 5.1.3.26) from Escherichia coli O157:H7 (see 2 papers)
GNU_ECO57 / Q8X7P7 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase; GlcNAc-P-P-Und 4-epimerase; EC 5.1.3.26 from Escherichia coli O157:H7 (see paper)
gne UDP-N-acetylglucosamine 4-epimerase; EC 5.1.3.7 from Escherichia coli O157:H7 (see paper)
28% identity, 99% coverage of query (100 bits)
cpsG polysaccharide capsule synthesis protein CpsG from Streptococcus iniae (see paper)
28% identity, 88% coverage of query (94.7 bits)
graE / AAA99939.1 dTDP-glucose dehydratase from Streptomyces violaceoruber (see paper)
28% identity, 97% coverage of query (79.3 bits)
3BHD_MYCNE / P0DX24 3-beta-hydroxysteroid dehydrogenase; 3beta-HSD; EC 1.1.1.51 from Mycolicibacterium neoaurum (Mycobacterium neoaurum) (see paper)
27% identity, 98% coverage of query (79.3 bits)
RMD_PSEAE / Q9HTB6 GDP-6-deoxy-D-mannose reductase; EC 1.1.1.281 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
Q9HTB6 GDP-4-dehydro-6-deoxy-D-mannose reductase (EC 1.1.1.281) from Pseudomonas aeruginosa (see paper)
26% identity, 97% coverage of query (77.8 bits)
6x3bB Structure of rmd from pseudomonas aeruginosa complexed with NADPH
26% identity, 97% coverage of query (72.8 bits)
6x3bA / Q9HTB6 Structure of rmd from pseudomonas aeruginosa complexed with NADPH
25% identity, 97% coverage of query (72.4 bits)
8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
25% identity, 98% coverage of query (72.4 bits)
6bwlA / Q3ESA4 X-ray structure of pal from bacillus thuringiensis (see paper)
25% identity, 100% coverage of query (71.6 bits)
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
24% identity, 99% coverage of query (71.6 bits)
tylA2 / Q54144 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces fradiae (see 2 papers)
26% identity, 100% coverage of query (70.9 bits)
ERG26_SCHPO / O43050 Sterol-4-alpha-carboxylate 3-dehydrogenase erg26, decarboxylating; C-3 sterol dehydrogenase erg26; C-4 decarboxylase erg26; Ergosterol biosynthetic protein 26; EC 1.1.1.170 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
24% identity, 98% coverage of query (67.4 bits)
gdh / Q54116 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Saccharopolyspora erythraea (see 2 papers)
26% identity, 100% coverage of query (65.1 bits)
UGA4E_THEGP / F8C4X8 UDP-glucuronate 4-epimerase; UGA4E; TgUGAE; EC 5.1.3.6 from Thermodesulfobacterium geofontis (strain OPF15)
24% identity, 97% coverage of query (65.1 bits)
6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
26% identity, 98% coverage of query (63.9 bits)
RMLB_SALTY / P26391 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
1keuA / P26391 The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from salmonella enterica serovar typhimurium with dtdp-d-glucose bound (see paper)
rmlB / CAA40115.1 dTDP-glucose 4,6-dehydratase from Salmonella enterica (see 6 papers)
22% identity, 99% coverage of query (63.9 bits)
agl12 / D4GU72 dTDP-glucose-4,6-dehydratase (EC 4.2.1.46) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL12_HALVD / D4GU72 Low-salt glycan biosynthesis protein Agl12; EC 4.2.1.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
26% identity, 99% coverage of query (63.9 bits)
1kewA The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from salmonella enterica serovar typhimurium with thymidine diphosphate bound
22% identity, 99% coverage of query (63.9 bits)
6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
26% identity, 98% coverage of query (63.9 bits)
oleD / Q8PDW5 2-alkyl-3-oxo-fatty acid reductase monomer (EC 1.1.1.412) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
OLED_XANCP / Q8PDW5 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
27% identity, 81% coverage of query (63.2 bits)
fcfA / Q6E7F2 dTDP-4-dehydro-6-deoxyglucose reductase [NAD(P)H] (EC 1.1.1.266) from Escherichia coli (see 2 papers)
FCF1_ECOLX / Q6E7F2 dTDP-4-dehydro-6-deoxyglucose reductase; dTDP-4-dehydro-6-deoxy-D-glucose reductase; dTDP-4-keto-6-deoxyglucose reductase; dTDP-6-deoxy-D-xylo-hex-4-ulopyranose reductase; EC 1.1.1.266 from Escherichia coli (see paper)
23% identity, 99% coverage of query (62.0 bits)
epsS / BAC55147.1 UDP-glucose 4-epimerase EpsS from Methylobacillus sp. 12S (see paper)
25% identity, 96% coverage of query (61.6 bits)
jadT / Q939Q5 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
26% identity, 99% coverage of query (61.6 bits)
RHM3 / Q9LH76 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM3 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM3_ARATH / Q9LH76 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3; Probable rhamnose biosynthetic enzyme 3; AtRHM3; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
24% identity, 99% coverage of query (61.6 bits)
3β-HSD/D1 / Q9FX01 plant 3β-hydroxysteroid dehydrogenase/C4-decarboxylase 1 (EC 1.1.1.418) from Arabidopsis thaliana (see 3 papers)
HSDD1_ARATH / Q9FX01 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1; At3BETAHSD/D1; 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase isoform 1-1; Reticulon-like protein B24; AtRTNLB24; Sterol-4-alpha-carboxylate 3-dehydrogenase 1, decarboxylating; EC 1.1.1.418 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
26% identity, 98% coverage of query (61.6 bits)
OLED_STRMK / B2FI29 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Stenotrophomonas maltophilia (strain K279a) (see paper)
B2FI29 2-alkyl-3-oxoalkanoate reductase (EC 1.1.1.412) from Stenotrophomonas maltophilia (see 2 papers)
25% identity, 98% coverage of query (61.2 bits)
RMLB_BACSU / P39630 dTDP-glucose 4,6-dehydratase; Spore coat polysaccharide biosynthesis protein SpsJ; EC 4.2.1.46 from Bacillus subtilis (strain 168) (see paper)
22% identity, 99% coverage of query (60.8 bits)
8sk0B / A0A1C5ADV9 Crystal structure of evds6 decarboxylase in ligand bound state (see paper)
30% identity, 79% coverage of query (60.5 bits)
T1SEU9 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Plagiochasma appendiculatum (see paper)
26% identity, 77% coverage of query (60.5 bits)
8sk0A Crystal structure of evds6 decarboxylase in ligand bound state
30% identity, 79% coverage of query (60.5 bits)
RmlB / b2041 dTDP-glucose 4,6-dehydratase 1 (EC 4.2.1.46) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
rfbB / P37759 dTDP-glucose 4,6-dehydratase 1 (EC 4.2.1.46) from Escherichia coli (strain K12) (see 6 papers)
RMLB1_ECOLI / P37759 dTDP-glucose 4,6-dehydratase 1; EC 4.2.1.46 from Escherichia coli (strain K12) (see paper)
24% identity, 99% coverage of query (59.7 bits)
hsdD / P9WQP7 3 β-hydroxysteroid dehydrogenase (EC 5.3.3.1; EC 1.1.1.145) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
3BHS_MYCTU / P9WQP7 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Cholesterol dehydrogenase; EC 1.1.1.145; EC 5.3.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WQP7 3beta-hydroxy-DELTA5-steroid dehydrogenase (EC 1.1.1.145) from Mycobacterium tuberculosis (see paper)
26% identity, 98% coverage of query (59.7 bits)
3βHSD-2 / A0A3Q7F6G4 3β-hydroxysteroid/C4-decarboxylase 2 (EC 1.1.1.418) from Solanum lycopersicum (see 3 papers)
25% identity, 98% coverage of query (59.3 bits)
Q7MH46 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Vibrio vulnificus (see paper)
27% identity, 95% coverage of query (58.9 bits)
oleE / Q9RR28 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces antibioticus (see paper)
OLEE_STRAT / Q9RR28 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Streptomyces antibioticus (see paper)
26% identity, 99% coverage of query (57.8 bits)
RMLB_MYCTU / P9WN65 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WN65 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Mycobacterium tuberculosis (see paper)
25% identity, 100% coverage of query (57.0 bits)
RHM1 / Q9SYM5 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM1 (EC 4.2.1.76) from Arabidopsis thaliana (see 3 papers)
RHM1_ARATH / Q9SYM5 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1; Protein REPRESSOR OF LRX1 1; Rhamnose biosynthetic enzyme 1; AtRHM1; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
25% identity, 81% coverage of query (57.0 bits)
6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
25% identity, 100% coverage of query (56.6 bits)
Rff / b3788 dTDP-glucose 4,6-dehydratase 2 (EC 4.2.1.46) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
rffG / P27830 dTDP-glucose 4,6-dehydratase 2 (EC 4.2.1.46) from Escherichia coli (strain K12) (see 5 papers)
RMLB2_ECOLI / P27830 dTDP-glucose 4,6-dehydratase 2; EC 4.2.1.46 from Escherichia coli (strain K12) (see 3 papers)
23% identity, 98% coverage of query (56.6 bits)
RMLB_STRGR / P29782 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Streptomyces griseus (see paper)
29% identity, 77% coverage of query (56.6 bits)
3BHS7_MOUSE / Q9EQC1 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; C(27) 3-beta-HSD; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.181 from Mus musculus (Mouse) (see 2 papers)
26% identity, 75% coverage of query (56.6 bits)
6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
25% identity, 100% coverage of query (56.6 bits)
6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
25% identity, 100% coverage of query (56.6 bits)
6kv9A / A0A003 Moee5 in complex with udp-glucuronic acid and NAD (see paper)
29% identity, 77% coverage of query (56.2 bits)
rfbB / AAA63157.1 TDP-glucose-dehydratase from Neisseria meningitidis (see paper)
24% identity, 98% coverage of query (56.2 bits)
3β-HSD/D2 / Q67ZE1 plant 3β-hydroxysteroid dehydrogenase/C4-decarboxylase 2 (EC 1.1.1.418) from Arabidopsis thaliana (see 3 papers)
HSDD2_ARATH / Q67ZE1 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; At3BETAHSD/D2; 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase isoform 1-2; Reticulon-like protein B19; AtRTNLB19; Sterol-4-alpha-carboxylate 3-dehydrogenase 2, decarboxylating; EC 1.1.1.418 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
24% identity, 98% coverage of query (56.2 bits)
P51110 Dihydroflavonol 4-reductase; DFR; Dihydrokaempferol 4-reductase; Flavanone 4-reductase; FNR; EC 1.1.1.219; EC 1.1.1.234 from Vitis vinifera (Grape)
26% identity, 71% coverage of query (55.8 bits)
8b9zP / Q9VPE2 Drosophila melanogaster complex i in the active state (dm1) (see paper)
25% identity, 79% coverage of query (55.1 bits)
6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
25% identity, 100% coverage of query (55.1 bits)
6kvcA Moee5 in complex with udp-glucose and NAD
28% identity, 77% coverage of query (55.1 bits)
1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
26% identity, 100% coverage of query (54.7 bits)
1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
26% identity, 100% coverage of query (54.7 bits)
RHM2 / Q9LPG6 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM2 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM2_ARATH / Q9LPG6 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2; NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
24% identity, 80% coverage of query (53.9 bits)
2p5uA / Q5SKQ2 Crystal structure of thermus thermophilus hb8 udp-glucose 4-epimerase complex with NAD
27% identity, 98% coverage of query (52.4 bits)
3ruhA Alternative analogs as viable substrates of udp-hexose 4-epimerases
23% identity, 85% coverage of query (52.4 bits)
3rufA Alternative analogs as viable substrates of udp-hexose 4-epimerases
23% identity, 85% coverage of query (52.4 bits)
3lu1A / Q7BJX9 Crystal structure analysis of wbgu: a udp-galnac 4-epimerase (see paper)
23% identity, 85% coverage of query (52.4 bits)
3bxxA Binding of two substrate analogue molecules to dihydroflavonol 4- reductase alters the functional geometry of the catalytic site
26% identity, 71% coverage of query (52.0 bits)
2nnlD Binding of two substrate analogue molecules to dihydroflavonol-4- reductase alters the functional geometry of the catalytic site
26% identity, 71% coverage of query (52.0 bits)
2c29D Structure of dihydroflavonol reductase from vitis vinifera at 1.8 a.
26% identity, 71% coverage of query (52.0 bits)
8fenA Panicum vigratum dihydroflavonol 4-reductase complexed with NADP and dhq
29% identity, 71% coverage of query (51.6 bits)
8femA / A0A8T0SQV2 Panicum vigratum dihydroflavonol 4-reductase complexed with NADP (see paper)
29% identity, 71% coverage of query (51.6 bits)
wbgU / Q7BJX9 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Plesiomonas shigelloides (see paper)
GNE_PLESH / Q7BJX9 UDP-N-acetylglucosamine 4-epimerase; UDP-GalNAc 4-epimerase; EC 5.1.3.7 from Plesiomonas shigelloides (Aeromonas shigelloides) (see 3 papers)
Q7BJX9 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Plesiomonas shigelloides (see 2 papers)
23% identity, 97% coverage of query (50.8 bits)
7ystA / P9WN67 Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chain b from mycobacterium tuberculosis
26% identity, 99% coverage of query (50.8 bits)
7ys9A Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chaina from mycobacterium tuberculosis
26% identity, 99% coverage of query (50.8 bits)
7ysmA Crystal structure of udp-glucose 4-epimerase (rv3634c) co-crystallized with udp-n-acetylglucosamine from mycobacterium tuberculosis
26% identity, 99% coverage of query (50.8 bits)
1sb9A Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-glucose
23% identity, 96% coverage of query (50.4 bits)
Q8KN66 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Pseudomonas aeruginosa (see paper)
1sb8A / Q8KN66 Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-n-acetylgalactosamine (see paper)
23% identity, 96% coverage of query (50.4 bits)
7k3pA / Q0P9C3 The structure of the udp-glc/glcnac 4-epimerase from the human pathogen campylobacter jejuni
24% identity, 95% coverage of query (48.1 bits)
3eheA / O29886 Crystal structure of udp-glucose 4 epimerase (gale-1) from archaeoglobus fulgidus
25% identity, 97% coverage of query (47.8 bits)
LYS2 / P07702 L-2-aminoadipate reductase (EC 1.2.1.95) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
LYS2_YEAST / P07702 L-2-aminoadipate reductase; Alpha-aminoadipate reductase; Alpha-AR; L-aminoadipate-semialdehyde dehydrogenase; EC 1.2.1.31; EC 1.2.1.95 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07702 L-2-aminoadipate reductase (EC 1.2.1.95) from Saccharomyces cerevisiae (see paper)
24% identity, 73% coverage of query (46.2 bits)
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