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Searching for up to 100 curated homologs for GFF1876 FitnessBrowser__Marino:GFF1876 (215 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

leuD / BAC65258.1 3-isopropylmalate dehydratase small subunit from Burkholderia multivorans (see paper)
    67% identity, 98% coverage of query (301 bits)

hbzJ / Q0QFQ6 maleate hydratase small subunit (EC 4.2.1.31) from Pseudomonas alcaligenes (see 3 papers)
Q0QFQ6 maleate hydratase (subunit 1/2) (EC 4.2.1.31) from Pseudomonas alcaligenes (see paper)
    59% identity, 98% coverage of query (267 bits)

leuD / Q8F4E5 isopropylmalate isomerase small subunit (EC 4.2.1.35) from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) (see paper)
    56% identity, 99% coverage of query (256 bits)

LEUD1_SALTY / P04787 3-isopropylmalate dehydratase small subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    56% identity, 92% coverage of query (233 bits)

LEUD_RHIJ3 / Q1MA52 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
    53% identity, 97% coverage of query (231 bits)

LeuD / b0071 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
leuD / P30126 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli (strain K12) (see 4 papers)
    56% identity, 92% coverage of query (225 bits)

O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    54% identity, 94% coverage of query (222 bits)

AN5886 alpha isopropylmalate isomerase (Eurofung) from Emericella nidulans (see paper)
    54% identity, 95% coverage of query (218 bits)

LEUC_YEAST / P07264 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    50% identity, 99% coverage of query (202 bits)

leu1 / CAB99455.1 3-isopropylmalate dehydratase, partial from Yarrowia lipolytica (see paper)
    52% identity, 83% coverage of query (171 bits)

LEUD_CORGL / Q8NQV7 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
    43% identity, 97% coverage of query (162 bits)

LEUD_MYCBO / P65278 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
P9WK95 3-isopropylmalate dehydratase (EC 4.2.1.33) from Mycobacterium tuberculosis (see paper)
    42% identity, 93% coverage of query (150 bits)

P9WK95 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    42% identity, 93% coverage of query (150 bits)

DVU2983 3-isopropylmalate dehydratase / (R)-citramalate isomerase, small subunit LeuD (EC 4.2.1.33; EC 4.2.1.35) from Desulfovibrio vulgaris Hildenborough JW710
    34% identity, 70% coverage of query (77.0 bits)

HtyD / K0E2G4 2-(4-hydroxybenzyl)-malate isomerase from Aspergillus rugulosus (see paper)
HTYD_ASPRU / K0E2G4 Aconitase htyD; L-homotyrosine biosynthetic cluster protein D; EC 4.2.1.- from Aspergillus rugulosus (Emericella rugulosa) (see paper)
    36% identity, 73% coverage of query (69.7 bits)

Build an alignment

Build an alignment for GFF1876 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

ACON3_ASPFU / Q4WBR0 Putative aconitate hydratase; Aconitase 3; EC 4.2.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
    28% identity, 76% coverage of query (60.1 bits)

B1P2N4 homoaconitate hydratase (EC 4.2.1.36) from Penicillium chrysogenum (see paper)
    27% identity, 78% coverage of query (55.5 bits)

lysF / GI|1628374 homoaconitase, mitochondrial; EC 4.2.1.36 from Emericella nidulans (see paper)
    26% identity, 74% coverage of query (51.2 bits)

LYS4_EMENI / Q92412 Homoaconitase, mitochondrial; Homoaconitate hydratase; EC 4.2.1.36 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
Q92412 homoaconitate hydratase (EC 4.2.1.36) from Aspergillus nidulans (see paper)
    26% identity, 74% coverage of query (50.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory