Sites on a Tree

 

Searching for up to 100 curated homologs for GFF2019 FitnessBrowser__psRCH2:GFF2019 (254 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    38% identity, 96% coverage of query (158 bits)

gdh / P12310 glcDH (EC 1.1.1.47) from Bacillus subtilis (strain 168) (see 6 papers)
    39% identity, 94% coverage of query (157 bits)

bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
    39% identity, 93% coverage of query (157 bits)

4wecA / A0QVJ7 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
    39% identity, 96% coverage of query (157 bits)

C5IFU0 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Lysinibacillus sphaericus (see 2 papers)
    37% identity, 95% coverage of query (155 bits)

A6N8S2 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Bacillus subtilis (see paper)
    38% identity, 94% coverage of query (155 bits)

P39482 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Priestia megaterium (see paper)
    36% identity, 96% coverage of query (154 bits)

1g6kA / P40288 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+
    35% identity, 96% coverage of query (153 bits)

DHG_PRIMG / P40288 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) (see paper)
P40288 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Priestia megaterium (see 9 papers)
    35% identity, 96% coverage of query (152 bits)

6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
    38% identity, 94% coverage of query (149 bits)

A0A068FPP9 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Bacillus sp. (in: Bacteria) (see paper)
    36% identity, 96% coverage of query (147 bits)

5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    37% identity, 96% coverage of query (147 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    37% identity, 94% coverage of query (145 bits)

salM / B0L7F4 5-chloro-5-deoxy-D-ribose 1-dehydrogenase from Salinispora tropica (see 2 papers)
    37% identity, 93% coverage of query (144 bits)

W5VJT8 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
    36% identity, 96% coverage of query (144 bits)

A0A2D0WG37 cyclohexanol dehydrogenase (EC 1.1.1.245) from Acidovorax sp. (see paper)
    37% identity, 95% coverage of query (143 bits)

A0A545BBR2 (1R,2S)-ephedrine 1-dehydrogenase (EC 1.1.1.423) from Arthrobacter sp. TS-15 (see paper)
    36% identity, 95% coverage of query (142 bits)

P39485 glucose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.47) from Priestia megaterium (see paper)
    35% identity, 94% coverage of query (141 bits)

3ay6B / P39485 Crystal structure of bacillus megaterium glucose dehydrogenase 4 a258f mutant in complex with nadh and d-glucose (see paper)
    35% identity, 94% coverage of query (141 bits)

gno / P50199 D-gluconate 5-dehydrogenase monomer from Gluconobacter oxydans (strain 621H) (see paper)
GNO_GLUOX / P50199 Gluconate 5-dehydrogenase; D-gluconate 5-dehydrogenase (NADP); Gluconate:NADP 5-oxidoreductase; GNO; EC 1.1.1.- from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
    38% identity, 98% coverage of query (141 bits)

FABG_RICPR / P50941 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Rickettsia prowazekii (strain Madrid E)
P50941 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Rickettsia prowazekii (see paper)
    36% identity, 94% coverage of query (140 bits)

ARMD4_ARMGA / A0A2H3D8Y2 Short-chain dehydrogenase/reductase ARMGADRAFT_1018421; Melleolide biosynthesis cluster protein ARMGADRAFT_1018421; EC 1.1.1.- from Armillaria gallica (Bulbous honey fungus) (Armillaria bulbosa) (see 9 papers)
    38% identity, 93% coverage of query (139 bits)

Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Synechococcus elongatus PCC 7942 = FACHB-805 (see paper)
    36% identity, 93% coverage of query (139 bits)

Q1J2J0 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Deinococcus geothermalis (see paper)
    40% identity, 95% coverage of query (139 bits)

W5VJM4 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
    35% identity, 96% coverage of query (138 bits)

A0A1Z3FWF0 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Rhodococcus sp. P14 (see paper)
    38% identity, 94% coverage of query (137 bits)

4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
    36% identity, 93% coverage of query (137 bits)

3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
    36% identity, 93% coverage of query (136 bits)

W5VJJ6 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens (see paper)
    35% identity, 96% coverage of query (135 bits)

cpnA / Q8GAV9 cyclopentanol dehydrogenase (EC 1.1.1.163) from Comamonas sp. (strain NCIMB 9872) (see 2 papers)
CPNA_COMS9 / Q8GAV9 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas sp. (strain NCIMB 9872) (see paper)
CPNA_COMTE / Q937L4 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
cpmB / CAD10799.1 cyclohexanol dehydrogenase from Comamonas testosteroni (see paper)
    38% identity, 94% coverage of query (135 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    35% identity, 95% coverage of query (134 bits)

xecD / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.268) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 5 papers)
HCDR1_XANP2 / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase; R-HPCDH; 2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase; Aliphatic epoxide carboxylation component III; Epoxide carboxylase component III; RHPCDH1; EC 1.1.1.268 from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 7 papers)
Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268) from Xanthobacter autotrophicus (see 4 papers)
2cfcA / Q56840 Structural basis for stereo selectivity in the (r)- and (s)-hydroxypropylethane thiosulfonate dehydrogenases (see paper)
    39% identity, 93% coverage of query (134 bits)

U5PUZ1 tropinone reductase I (EC 1.1.1.206) from Withania somnifera (see paper)
    33% identity, 96% coverage of query (134 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    36% identity, 93% coverage of query (134 bits)

Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
    36% identity, 93% coverage of query (134 bits)

3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
    36% identity, 94% coverage of query (134 bits)

TR1 / P50162 tropinone reductase (EC 1.1.1.206) from Datura stramonium (see paper)
TRN1_DATST / P50162 Tropinone reductase 1; Tropine dehydrogenase; Tropinone reductase I; TR-I; EC 1.1.1.206 from Datura stramonium (Jimsonweed) (Common thornapple) (see 2 papers)
P50162 tropinone reductase I (EC 1.1.1.206) from Datura stramonium (see 2 papers)
    31% identity, 96% coverage of query (134 bits)

1ae1B / P50162 Tropinone reductase-i complex with NADP (see paper)
    31% identity, 96% coverage of query (133 bits)

GMDH_GLUOX / Q5FPE5 Glucose 1-dehydrogenase; EC 1.1.1.119 from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
    36% identity, 96% coverage of query (133 bits)

YgcW / b2774 putative deoxygluconate dehydrogenase from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    35% identity, 95% coverage of query (133 bits)

4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
    36% identity, 94% coverage of query (133 bits)

AT1G24360 / P33207 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic (EC 1.1.1.100) from Arabidopsis thaliana (see paper)
    32% identity, 98% coverage of query (132 bits)

ltxD / Q5V8A5 lyngbyatoxin A monooxygenase from Lyngbya majuscula (see 3 papers)
    35% identity, 94% coverage of query (132 bits)

SDR / F1SWA0 zerumbone synthase (EC 1.1.1.326) from Zingiber zerumbet (see paper)
ZERSY_ZINZE / F1SWA0 Zerumbone synthase; EC 1.1.1.326 from Zingiber zerumbet (Shampoo ginger) (Amomum zerumbet) (see paper)
F1SWA0 zerumbone synthase (EC 1.1.1.326) from Zingiber zerumbet (see 2 papers)
    36% identity, 94% coverage of query (132 bits)

3BHD2_EGGLE / C8WGQ3 3beta-hydroxysteroid dehydrogenase 2; 3beta-HSDH 2; 3beta-hydroxycholanate 3-dehydrogenase (NAD(+)) 2; NAD-dependent bile acid 3beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.391 from Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B) (Eubacterium lentum) (see paper)
C8WGQ3 3beta-hydroxycholanate 3-dehydrogenase (NAD+) (EC 1.1.1.391) from Eggerthella lenta (see paper)
    37% identity, 98% coverage of query (132 bits)

LINX_SPHIU / D4Z260 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
    37% identity, 94% coverage of query (132 bits)

Q58LW6 D-arabinitol dehydrogenase (NADP+) (EC 1.1.1.287) from Gluconobacter oxydans (see paper)
    37% identity, 94% coverage of query (132 bits)

A0A6B7HCZ2 tropinone reductase I (EC 1.1.1.206) from Przewalskia tangutica (see paper)
    30% identity, 100% coverage of query (131 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    34% identity, 93% coverage of query (131 bits)

Q4J9F2 alcohol dehydrogenase (EC 1.1.1.1) from Sulfolobus acidocaldarius (see 2 papers)
    38% identity, 95% coverage of query (131 bits)

A0A088MI02 tropinone reductase I (EC 1.1.1.206) from Brugmansia arborea (see paper)
    30% identity, 99% coverage of query (131 bits)

4fn4A / Q4J9F2 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius (see paper)
    38% identity, 95% coverage of query (131 bits)

Q9AR59 tropinone reductase I (EC 1.1.1.206) from Solanum tuberosum (see paper)
    31% identity, 96% coverage of query (131 bits)

Pf1N1B4_412 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Pseudomonas fluorescens FW300-N1B4
    34% identity, 96% coverage of query (130 bits)

Q5SLC4 aldose 1-dehydrogenase (NAD+) (EC 1.1.1.121) from Thermus thermophilus (see paper)
    39% identity, 94% coverage of query (130 bits)

chnA / Q9F7E0 cyclohexanol dehydrogenase (EC 1.1.1.245) from Acinetobacter sp. (strain SE19) (see 4 papers)
CHNA_ACISS / Q9F7E0 Cyclohexanol dehydrogenase; EC 1.1.1.245 from Acinetobacter sp. (strain SE19) (see paper)
    38% identity, 93% coverage of query (130 bits)

YjgU / b4266 5-keto-D-gluconate 5-reductase (EC 1.1.1.69) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
idnO / P0A9P9 5-keto-D-gluconate 5-reductase (EC 1.1.1.69) from Escherichia coli (strain K12) (see 4 papers)
IDNO_ECOLI / P0A9P9 5-keto-D-gluconate 5-reductase; EC 1.1.1.69 from Escherichia coli (strain K12) (see paper)
    35% identity, 94% coverage of query (130 bits)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    34% identity, 94% coverage of query (130 bits)

R4QQK2 tropinone reductase I (EC 1.1.1.206) from Anisodus luridus (see paper)
    31% identity, 96% coverage of query (130 bits)

GOLD_LISIN / Q92EU6 NAD-dependent glycerol dehydrogenase; Dha-forming NAD-dependent glycerol dehydrogenase; EC 1.1.1.6 from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) (see paper)
    36% identity, 93% coverage of query (130 bits)

A0JC04 octanol dehydrogenase (EC 1.1.1.73) from Ogataea wickerhamii (see paper)
    35% identity, 93% coverage of query (130 bits)

4cr6A Crystal structure of the n-acetyl-d-mannosamine dehydrogenase without substrates
    40% identity, 93% coverage of query (130 bits)

P22441 N-acylmannosamine 1-dehydrogenase (EC 1.1.1.233) from Flavobacterium sp. (see paper)
    38% identity, 97% coverage of query (129 bits)

5t5qC / Q2YL80 Crystal structure of short-chain dehydrogenase/reductase sdr:glucose/ribitol dehydrogenase from brucella melitensis
    33% identity, 94% coverage of query (129 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    36% identity, 94% coverage of query (129 bits)

B2L2W8 tropinone reductase I (EC 1.1.1.206) from Anisodus acutangulus (see 3 papers)
    30% identity, 96% coverage of query (129 bits)

chnA / Q5P8S7 cyclohexanol dehydrogenase from Aromatoleum aromaticum (strain EbN1) (see paper)
4ureB / Q5P8S7 Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1 (see paper)
    36% identity, 94% coverage of query (129 bits)

6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
    36% identity, 93% coverage of query (129 bits)

TPRL1_ERYCB / H9BFQ0 Tropinone reductase-like 1; EC 1.1.1.- from Erythroxylum coca (Coca plant) (see paper)
    36% identity, 95% coverage of query (129 bits)

Q308C1 D-arabinitol 4-dehydrogenase (EC 1.1.1.11); D-arabinitol dehydrogenase (NADP+) (EC 1.1.1.287) from Gluconobacter oxydans (see paper)
    36% identity, 94% coverage of query (129 bits)

FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
    36% identity, 93% coverage of query (129 bits)

L7QI79 tropinone reductase I (EC 1.1.1.206) from Withania coagulans (see paper)
    32% identity, 96% coverage of query (129 bits)

2d1yA Crystal structure of tt0321 from thermus thermophilus hb8
    39% identity, 94% coverage of query (129 bits)

4urfB Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1
    36% identity, 94% coverage of query (129 bits)

4urfA Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1
    36% identity, 94% coverage of query (129 bits)

1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
    36% identity, 93% coverage of query (129 bits)

4cr8D / P22441 Crystal structure of the n-acetyl-d-mannosamine dehydrogenase with nad (see paper)
    39% identity, 93% coverage of query (128 bits)

BN592_00769 / R7B6R4 3α-hydroxysteroid dehydrogenase (EC 1.1.1.52) from Eggerthella sp. CAG:298 (see paper)
R7B6R4 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213) from Eggerthella sp. CAG:298 (see paper)
    37% identity, 93% coverage of query (128 bits)

Q9I1X3 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Pseudomonas aeruginosa (see paper)
    33% identity, 95% coverage of query (128 bits)

SILD_FORIN / Q94KL7 Secoisolariciresinol dehydrogenase; EC 1.1.1.331 from Forsythia intermedia (Border forsythia) (Forsythia suspensa x Forsythia viridissima) (see paper)
    33% identity, 96% coverage of query (128 bits)

AFO85456.1 reductase/oxidase from Marinactinospora thermotolerans (see paper)
    37% identity, 94% coverage of query (128 bits)

8cxaA / A0QVD5 Crystal structure of 3-oxoacyl-[acyl-carrier-protein] reductase from mycobacterium smegmatis with bound NAD
    37% identity, 94% coverage of query (128 bits)

PfGW456L13_2119 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Pseudomonas fluorescens GW456-L13
    33% identity, 96% coverage of query (128 bits)

FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    36% identity, 93% coverage of query (128 bits)

STCU_EMENI / Q00791 Versicolorin reductase stcU; Sterigmatocystin biosynthesis cluster protein U; EC 1.3.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 8 papers)
stcU versicolorin reductase; EC 1.1.-.- from Emericella nidulans (see paper)
    35% identity, 93% coverage of query (128 bits)

6zyzA Structure of the borneol dehydrogenases of salvia rosmarinus with NAD+ (see paper)
    35% identity, 95% coverage of query (128 bits)

A0A2K9VPX3 D-arabinitol 4-dehydrogenase (EC 1.1.1.11) from Gluconobacter sp. JX-05 (see paper)
    36% identity, 94% coverage of query (127 bits)

YfeF / b2426 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
ucpA / P37440 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli (strain K12) (see 6 papers)
    35% identity, 95% coverage of query (127 bits)

7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
    35% identity, 96% coverage of query (127 bits)

BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
    35% identity, 96% coverage of query (127 bits)

Pf6N2E2_5967 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Pseudomonas fluorescens FW300-N2E2
    34% identity, 96% coverage of query (127 bits)

1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
    35% identity, 93% coverage of query (127 bits)

CBR2_MOUSE / P08074 Carbonyl reductase [NADPH] 2; Adipocyte protein P27; AP27; Lung carbonyl reductase; LCR; NADPH-dependent carbonyl reductase 2; EC 1.1.1.184 from Mus musculus (Mouse) (see 3 papers)
    35% identity, 93% coverage of query (126 bits)

1cydA / P08074 Carbonyl reductase complexed with NADPH and 2-propanol (see paper)
    35% identity, 93% coverage of query (126 bits)

TPRL2_ERYCB / H9BFQ1 Tropinone reductase-like 2; EC 1.1.1.- from Erythroxylum coca (Coca plant) (see paper)
    35% identity, 95% coverage of query (126 bits)

Elen_0198 / C8WJW0 NAD-dependent bile acid 3β-dehydrogenase (EC 1.1.1.391) from Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B) (see 4 papers)
3BHD1_EGGLE / C8WJW0 3beta-hydroxysteroid dehydrogenase 1; 3beta-HSDH 1; 3beta-hydroxycholanate 3-dehydrogenase (NAD(+)) 1; NAD-dependent bile acid 3beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.391 from Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B) (Eubacterium lentum) (see paper)
C8WJW0 3beta-hydroxycholanate 3-dehydrogenase (NAD+) (EC 1.1.1.391) from Eggerthella lenta (see paper)
    33% identity, 97% coverage of query (126 bits)

1zk1A Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and NAD
    34% identity, 94% coverage of query (126 bits)

1zjzA Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and NAD
    34% identity, 94% coverage of query (126 bits)

1zjyA Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and nadh
    34% identity, 94% coverage of query (126 bits)

GME73_PESMI / A0A5B8YU81 Short-chain dehydrogenase/reductase GME11373; Dibenzodioxocinones biosynthesis cluster protein GME11373; EC 1.1.1.- from Pestalotiopsis microspora (see 2 papers)
    33% identity, 98% coverage of query (125 bits)

Build an alignment

Build an alignment for GFF2019 and 100 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory