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Searching for up to 100 curated homologs for GFF2076 FitnessBrowser__psRCH2:GFF2076 (414 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DadR / b1189 D-amino acid dehydrogenase (EC 1.4.5.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
dadA / P0A6J5 D-amino acid dehydrogenase (EC 1.4.5.1) from Escherichia coli (strain K12) (see 22 papers)
DADA_ECOLI / P0A6J5 D-amino acid dehydrogenase; D-alanine dehydrogenase; EC 1.4.99.- from Escherichia coli (strain K12) (see 4 papers)
dadA / AAC36880.1 D-amino acid dehydrogenase from Escherichia coli (see paper)
    40% identity, 100% coverage of query (299 bits)

DADA1_PSEAE / Q9HTQ0 D-amino acid dehydrogenase 1; D-alanine dehydrogenase 1; EC 1.4.99.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9HTQ0 D-arginine dehydrogenase (EC 1.4.99.6) from Pseudomonas aeruginosa (see paper)
    40% identity, 100% coverage of query (290 bits)

AZOBR_RS08020 D-alanine dehydrogenase (EC 1.4.99.-) from Azospirillum brasilense Sp245
    39% identity, 100% coverage of query (289 bits)

DADA_KLEAE / O30745 D-amino acid dehydrogenase; D-alanine dehydrogenase; EC 1.4.99.- from Klebsiella aerogenes (Enterobacter aerogenes) (see paper)
    40% identity, 100% coverage of query (287 bits)

Psest_3793 D-alanine dehydrogenase (EC 1.4.99.-) from Pseudomonas stutzeri RCH2
    40% identity, 100% coverage of query (285 bits)

Ac3H11_4848 D-alanine dehydrogenase (EC 1.4.99.-) from Acidovorax sp. GW101-3H11
    36% identity, 98% coverage of query (256 bits)

RR42_RS25930 glycine dehydrogenase (deaminating) (EC 1.4.1.10) from Cupriavidus basilensis FW507-4G11
    34% identity, 99% coverage of query (200 bits)

Build an alignment

Build an alignment for GFF2076 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

dadA / A3KEZ1 D-amino acid dehydrogenase (EC 1.4.5.1) from Helicobacter pylori (see paper)
DADA_HELPX / A3KEZ1 D-amino acid dehydrogenase; DAD; EC 1.4.5.1 from Helicobacter pylori (Campylobacter pylori) (see paper)
A3KEZ1 D-amino acid dehydrogenase (quinone) (EC 1.4.5.1); D-arginine dehydrogenase (EC 1.4.99.6) from Helicobacter pylori (see 2 papers)
    26% identity, 90% coverage of query (116 bits)

lhpB / Q88NF6 D-hydroxyproline dehydrogenase subunit from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    28% identity, 94% coverage of query (102 bits)

GLYOX_PSEPK / Q88Q83 Glycine oxidase; GO; EC 1.4.3.19 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
Q88Q83 glycine oxidase (EC 1.4.3.19) from Pseudomonas putida (see paper)
    25% identity, 95% coverage of query (88.2 bits)

amaD / Q88GX1 D-lysine oxidase (EC 1.4.3.3) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
    26% identity, 96% coverage of query (75.9 bits)

thiO / O31616 glycine oxidase monomer (EC 1.4.3.19; EC 1.4.3.3) from Bacillus subtilis (strain 168) (see 3 papers)
GLYOX_BACSU / O31616 Glycine oxidase; GO; EC 1.4.3.19 from Bacillus subtilis (strain 168) (see 5 papers)
    25% identity, 71% coverage of query (72.4 bits)

3if9A / O31616 Crystal structure of glycine oxidase g51s/a54r/h244a mutant in complex with inhibitor glycolate (see paper)
    25% identity, 71% coverage of query (71.2 bits)

1ng3A Complex of thio (glycine oxidase) with acetyl-glycine
    25% identity, 71% coverage of query (71.2 bits)

lhpB / Q9I477 D-hydroxyproline dehydrogenase β subunit from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    30% identity, 71% coverage of query (64.3 bits)

6j38A / X5IYZ1 Crystal structure of cmis2 (see paper)
    29% identity, 72% coverage of query (62.8 bits)

6j39A Crystal structure of cmis2 with inhibitor
    29% identity, 72% coverage of query (62.8 bits)

6pxsA / Q11HA4 Crystal structure of iminodiacetate oxidase (idaa) from chelativorans sp. Bnc1 (see paper)
    25% identity, 99% coverage of query (52.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory