Searching for up to 100 curated homologs for GFF209 FitnessBrowser__WCS417:GFF209 (214 a.a.)
Found high-coverage hits (≥70%) to 33 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
MetI / b0198 L-methionine/D-methionine ABC transporter membrane subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
MetI / P31547 L-methionine/D-methionine ABC transporter membrane subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 2 papers)
METI_ECOLI / P31547 D-methionine transport system permease protein MetI from Escherichia coli (strain K12) (see 3 papers)
P31547 ABC-type methionine transporter (subunit 1/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P31547 MetI, D-methionine transport system permease protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 4 papers)
51% identity, 100% coverage of query (167 bits)
METP_BACSU / O32168 Methionine import system permease protein MetP from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.24.2 / O32168 MetP (M) (aka YusB), component of The L- and D-methionine porter (also transports methionine sulfoxide from Bacillus subtilis subsp. subtilis str. 168 (see 2 papers)
44% identity, 95% coverage of query (163 bits)
TC 3.A.1.24.5 / Q9HT69 D-methionine ABC transporter membrane protein, component of L-Histidine uptake porter, MetIQN from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
46% identity, 100% coverage of query (154 bits)
TC 3.A.1.24.3 / Q8K8K7 AtmE, component of The methionine porter, AtmBDE from Streptococcus pyogenes serotype M3 (see 2 papers)
42% identity, 81% coverage of query (109 bits)
TC 3.A.1.24.4 / Q8NSN3 ABC-type transporter, permease components, component of L-Methionine uptake porter, MetQNI from Corynebacterium glutamicum
40% identity, 95% coverage of query (109 bits)
AO356_09615 ABC transporter for L-Histidine, permease component from Pseudomonas fluorescens FW300-N2C3
32% identity, 79% coverage of query (72.0 bits)
Build an alignment for GFF209 and 6 homologs with ≥ 30% identity
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GBUB_LISM4 / Q9RR45 Glycine betaine/carnitine transport permease protein GbuB from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
27% identity, 95% coverage of query (65.5 bits)
OPUCB_LISM4 / G2JZ43 Carnitine transport permease protein OpuCB from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCB_LISMN / Q9KHT8 Carnitine transport permease protein OpuCB from Listeria monocytogenes (see paper)
28% identity, 93% coverage of query (62.0 bits)
TC 3.A.1.12.9 / Q8U4S4 OtaB, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see paper)
30% identity, 98% coverage of query (61.6 bits)
ARTQ_BACSU / P54536 Arginine transport system permease protein ArtQ from Bacillus subtilis (strain 168) (see paper)
27% identity, 83% coverage of query (61.2 bits)
TC 3.A.1.12.12 / Q9HTI7 Probable permease of ABC transporter, component of The CbcWV/CbcX (choline)/CaiX (carnitine)/BetX (betaine) transporter with 3 binding receptors for distinct quaternary ammonium compounds. Only the ligand-bound receptor binds to the transporter with high affinity from Pseudomonas aeruginosa (see paper)
29% identity, 77% coverage of query (60.8 bits)
OUSW_DICD3 / E0SCY2 Glycine betaine/choline transport system permease protein OusW from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
29% identity, 94% coverage of query (60.5 bits)
Pf6N2E2_4682 ABC transporter for Carnitine, permease component from Pseudomonas fluorescens FW300-N2E2
29% identity, 77% coverage of query (59.7 bits)
AO356_13810 ABC transporter for Carnitine, permease component from Pseudomonas fluorescens FW300-N2C3
29% identity, 77% coverage of query (59.3 bits)
TC 3.A.1.3.25 / Q9CES5 Glutamine ABC transporter permease and substrate binding protein protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
26% identity, 91% coverage of query (59.3 bits)
AO356_09910 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
26% identity, 76% coverage of query (58.5 bits)
U5LHK3 ABC-type quaternary amine transporter (subunit 2/3) (EC 7.6.2.9) from Bacillus infantis (see paper)
31% identity, 76% coverage of query (58.5 bits)
AO353_07785 ABC transporter for Carnitine, permease component from Pseudomonas fluorescens FW300-N2E3
28% identity, 77% coverage of query (57.4 bits)
TC 3.A.1.3.12 / P73544 BgtB aka GLNH aka SLL1270, component of Arginine/lysine/histidine/glutamine porter (see paper)
23% identity, 92% coverage of query (57.4 bits)
TC 3.A.1.12.6 / Q9KKE2 HutW aka HISW, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
26% identity, 95% coverage of query (57.4 bits)
TC 3.A.1.12.7 / Q92N36 ChoW, component of High affinity (3 μM) choline-specific uptake system from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
29% identity, 76% coverage of query (56.6 bits)
TC 3.A.1.12.8 / Q93A34 BilEB aka OpuBB protein, component of A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) from Listeria monocytogenes (see paper)
30% identity, 76% coverage of query (56.2 bits)
EGTUB_LISMO / Q8Y775 Probable ergothioneine transporter EgtUBC from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) (see 2 papers)
30% identity, 76% coverage of query (56.2 bits)
A0A077T980 ABC-type quaternary amine transporter (subunit 3/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
29% identity, 81% coverage of query (55.5 bits)
OPUCD_LISM4 / G2JZ41 Carnitine transport permease protein OpuCD from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCD_LISMN / Q9KHT6 Carnitine transport permease protein OpuCD from Listeria monocytogenes (see paper)
29% identity, 81% coverage of query (55.1 bits)
PHNE_MYCS2 / A0QQ68 Phosphate-import permease protein PhnE from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
27% identity, 81% coverage of query (53.5 bits)
OPUCB_BACSU / O34878 Glycine betaine/carnitine/choline transport system permease protein OpuCB from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.12.4 / O34878 OPCB aka OpuCB, component of Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate from Bacillus subtilis (see 2 papers)
30% identity, 71% coverage of query (53.1 bits)
EGTUB_ENTFA / Q837Z8 Probable ergothioneine transporter EgtUBC from Enterococcus faecalis (strain ATCC 700802 / V583) (see paper)
32% identity, 78% coverage of query (53.1 bits)
OPUAB_BACSU / P46921 Glycine betaine transport system permease protein OpuAB from Bacillus subtilis (strain 168) (see 2 papers)
P46921 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see 2 papers)
TC 3.A.1.12.2 / P46921 OPAB aka OpuAB, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis (see 3 papers)
27% identity, 83% coverage of query (52.4 bits)
OPUCD_BACSU / O34742 Glycine betaine/carnitine/choline transport system permease protein OpuCD from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.12.4 / O34742 OPCD aka OpuCD, component of Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate from Bacillus subtilis (see 2 papers)
28% identity, 78% coverage of query (51.6 bits)
OsrA / b2678 glycine betaine ABC transporter membrane subunit ProW (EC 7.6.2.9) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
proW / P14176 glycine betaine ABC transporter membrane subunit ProW (EC 7.6.2.9) from Escherichia coli (strain K12) (see paper)
PROW_ECOLI / P14176 Glycine betaine/proline betaine transport system permease protein ProW from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.12.1 / P14176 ProW aka B2678, component of Glycine betaine/proline porter, ProU or ProVWX (also transports proline betaine, carnitine, dimethyl proline, homobetaine, γ-butyrobetaine and choline with low affinity) from Escherichia coli (see 5 papers)
26% identity, 89% coverage of query (51.6 bits)
4ymwC Crystal structure of an amino acid abc transporter with histidines
25% identity, 89% coverage of query (50.1 bits)
4ymtC / Q8RCC3 Crystal structure of an amino acid abc transporter complex with arginines (see paper)
25% identity, 89% coverage of query (50.1 bits)
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Lawrence Berkeley National Laboratory