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Searching for up to 100 curated homologs for GFF2134 FitnessBrowser__WCS417:GFF2134 (739 a.a.)

Found high-coverage hits (≥70%) to 8 curated proteins.

Removed hits that are identical to the query, leaving 7

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PP_3622 vanillin dehydrogenase, iorB-like component from Pseudomonas putida KT2440
    85% identity, 99% coverage of query (1249 bits)

A0A5K7VFT8 aldehyde dehydrogenase (FAD-independent) (subunit 1/2) (EC 1.2.99.7) from Pseudomonas nitroreducens (see paper)
    35% identity, 98% coverage of query (362 bits)

iorB / Q51698 isoquinoline 1-oxidoreductase subunit β (EC 1.3.99.16) from Brevundimonas diminuta (see paper)
iorB / CAA88754.1 isoquinoline 1-oxidoreductase from Brevundimonas diminuta (see paper)
    30% identity, 98% coverage of query (285 bits)

A0A0Y0MN26 nicotine dehydrogenase (EC 1.5.99.4) from Shinella sp. HZN7 (see paper)
    30% identity, 98% coverage of query (270 bits)

Build an alignment

Build an alignment for GFF2134 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

8gy3C / Q5FTD1 Cryo-em structure of membrane-bound aldehyde dehydrogenase from gluconobacter oxydans
    29% identity, 92% coverage of query (231 bits)

nicB / Q88FX8 nicotinate hydroxylase large subunit (EC 1.17.2.1) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
NICB_PSEPK / Q88FX8 Nicotinate dehydrogenase subunit B; Nicotinate degradation protein B; Nicotinate dehydrogenase large subunit; EC 1.17.2.1 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
Q88FX8 nicotinate dehydrogenase (EC 1.17.1.5); nicotinate dehydrogenase (cytochrome) (EC 1.17.2.1) from Pseudomonas putida (see paper)
    28% identity, 97% coverage of query (194 bits)

B1PHD2 nicotinate dehydrogenase (EC 1.17.1.5) from Comamonas testosteroni (see paper)
    28% identity, 98% coverage of query (193 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory