Sites on a Tree

 

Searching for up to 100 curated homologs for GFF2199 FitnessBrowser__Marino:GFF2199 (415 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PGA1_c12670 D-lactate transporter, substrate binding component from Phaeobacter inhibens BS107
    31% identity, 89% coverage of query (183 bits)

Build an alignment

Build an alignment for GFF2199 and 1 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

3i09A / A0A0H2WF95 Crystal structure of a periplasmic binding protein (bma2936) from burkholderia mallei at 1.80 a resolution
    25% identity, 92% coverage of query (122 bits)

3i45A / Q2RWX8 Crystal structure of putative twin-arginine translocation pathway signal protein from rhodospirillum rubrum atcc 11170
    26% identity, 80% coverage of query (90.5 bits)

TC 3.A.1.4.10 / Q8DQI1 ABC transporter substrate-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    24% identity, 85% coverage of query (80.1 bits)

4gnrA / J9PBT7 1.0 angstrom resolution crystal structure of the branched-chain amino acid transporter substrate binding protein livj from streptococcus pneumoniae str. Canada mdr_19a in complex with isoleucine
    24% identity, 83% coverage of query (77.8 bits)

TC 3.A.1.4.5 / Q8NRW1 UrtB, component of The high affinity urea/thiourea/hydroxyurea porter from Corynebacterium glutamicum (see paper)
    23% identity, 85% coverage of query (75.5 bits)

BRAC_PSEAE / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; LIVAT-BP; Leu/Ile/Val/Thr/Ala-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
TC 3.A.1.4.8 / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    26% identity, 81% coverage of query (73.6 bits)

7s6eB / Q0I663 Crystal structure of urta from synechococcus cc9311 in complex with urea and calcium
    23% identity, 79% coverage of query (68.9 bits)

4mlcA / B8FZ96 Abc transporter substrate-binding protein fromdesulfitobacterium hafniense
    27% identity, 70% coverage of query (67.4 bits)

8hicA / Q7V3V9 Crystal structure of urta from prochlorococcus marinus str. Mit 9313 in complex with urea and calcium
    24% identity, 71% coverage of query (65.9 bits)

4q6bA Crystal structure of abc transporter substrate-binding protein fromdesulfitobacterium hafniense complex with leu
    26% identity, 70% coverage of query (63.9 bits)

Pf6N2E2_2921 ABC transporter for L-leucine/L-phenylalanine/D-alanine, substrate-binding component LivK from Pseudomonas fluorescens FW300-N2E2
    24% identity, 82% coverage of query (59.3 bits)

fmdD / CAA75186.1 amide-urea binding protein from Methylophilus methylotrophus (see paper)
    24% identity, 78% coverage of query (56.6 bits)

4n0qB / Q8YEE8 Crystal structure of an abc transporter, substrate-binding protein from brucella melitensis 16m in complex with l-leucine using a crystal grown in a crystal former (microlytic)
    23% identity, 76% coverage of query (55.5 bits)

4zpjA / D1C6A8 Abc transporter substrate-binding protein from sphaerobacter thermophilus
    24% identity, 84% coverage of query (48.1 bits)

TC 3.A.1.4.4 / Q9L3S6 UrtA, component of The high-affinity (<1 μM) urea porter (see paper)
    21% identity, 77% coverage of query (47.8 bits)

3td9A / Q9X0L9 Crystal structure of a leucine binding protein livk (tm1135) from thermotoga maritima msb8 at 1.90 a resolution
    23% identity, 73% coverage of query (45.4 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory