Searching for up to 100 curated homologs for GFF2282 FitnessBrowser__WCS417:GFF2282 (451 a.a.)
Found high-coverage hits (≥70%) to 58 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TAD1 / A0A0U2UYC4 trans-aconitate decarboxylase (EC 4.1.1.113) from Ustilago maydis (see paper)
TAD1_USTMD / A0A0U2UYC4 Trans-aconitate decarboxylase 1; Itaconic acid/2-hydroxyparaconate biosynthesis cluster protein TAD1; EC 4.1.1.113 from Ustilago maydis (Corn smut fungus) (see 2 papers)
A0A0U2UYC4 trans-aconitate decarboxylase (EC 4.1.1.113) from Ustilago maydis (see paper)
49% identity, 97% coverage of query (438 bits)
YBN5_SCHPO / O42889 Uncharacterized protein C8E4.05c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
48% identity, 98% coverage of query (436 bits)
2SL_DICD3 / E0SKP1 N-acetyl-S-(2-succino)cysteine lyase; S-(2-succino) lyase; 2SL; EC 4.3.2.- from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
42% identity, 98% coverage of query (343 bits)
pcaB / AAC37149.1 beta-carboxy-cis,cis-muconate cycloisomerase from Acinetobacter baylyi (see 11 papers)
43% identity, 97% coverage of query (342 bits)
RR42_RS32055 3-carboxymuconate cycloisomerase PcaB (EC 5.5.1.2) from Cupriavidus basilensis FW507-4G11
48% identity, 96% coverage of query (340 bits)
2SL_ENTI1 / E6LDH5 N-acetyl-S-(2-succino)cysteine lyase; S-(2-succino) lyase; 2SL; EC 4.3.2.- from Enterococcus italicus (strain DSM 15952 / CCUG 50447 / LMG 22039 / TP 1.5) (see paper)
39% identity, 98% coverage of query (329 bits)
pcaB2 / Q2HNY9 3-carboxymuconate lactonizing enzyme type 2 (EC 5.5.1.2) from Hydrogenophaga intermedia (see 2 papers)
40% identity, 99% coverage of query (303 bits)
CREDH_STRDJ / K4R6W4 Nitrosuccinate lyase; EC 4.3.99.5 from Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768) (see paper)
39% identity, 98% coverage of query (276 bits)
MJ0929 / Q58339 adenylosuccinate lyase (EC 4.3.2.2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
36% identity, 94% coverage of query (270 bits)
creD / A0A0K2JL82 nitrosuccinate lyase (EC 4.3.99.5) from Streptomyces cremeus (see paper)
CRED_STRCM / A0A0K2JL82 Nitrosuccinate lyase; EC 4.3.99.5 from Streptomyces cremeus (see 3 papers)
A0A0K2JL82 nitrosuccinate lyase (EC 4.3.99.5) from Streptomyces cremeus (see paper)
37% identity, 98% coverage of query (243 bits)
toyF / B6CWI9 succinylo-toyocamycin phosphate lyase from Streptomyces rimosus (see paper)
36% identity, 96% coverage of query (227 bits)
5xnzA / A0A0K2JL82 Crystal structure of cred complex with fumarate (see paper)
36% identity, 98% coverage of query (222 bits)
PUR8_THEMA / Q9X0I0 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
31% identity, 93% coverage of query (211 bits)
PUR8_STAAW / Q7A0G9 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Staphylococcus aureus (strain MW2) (see paper)
Q7A0G9 adenylosuccinate lyase (EC 4.3.2.2) from Staphylococcus aureus (see paper)
30% identity, 96% coverage of query (202 bits)
2x75A / Q7A0G9 Staphylococcus aureus adenylosuccinate lyase (see paper)
30% identity, 96% coverage of query (199 bits)
Q2HNZ1 3-Carboxy-cis,cis-muconate cycloisomerase (EC 5.5.1.2) from Agrobacterium tumefaciens (see paper)
35% identity, 75% coverage of query (188 bits)
Build an alignment for GFF2282 and 16 homologs with ≥ 30% identity
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PUR8_BACSU / P12047 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; Glutamyl--tRNA ligase regulatory factor; EC 4.3.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
P12047 adenylosuccinate lyase (EC 4.3.2.2) from Bacillus subtilis (see paper)
purB / GI|143366 (glutamyl-trna synthetase regulatory factor); EC 4.3.2.2 from Bacillus subtilis (see 4 papers)
29% identity, 96% coverage of query (187 bits)
pcaB / AAF34266.1 3-carboxy-cis,cis-muconate cycloisomerase from Agrobacterium tumefaciens (see 2 papers)
35% identity, 75% coverage of query (184 bits)
Q8ZY28 adenylosuccinate lyase (EC 4.3.2.2) from Pyrobaculum aerophilum (see paper)
35% identity, 80% coverage of query (146 bits)
5nx9D / A0A384E0N4 Crystal structure of neanderthal adenylosuccinate lyase (adsl) in complex with its products amp and fumarate (see paper)
27% identity, 94% coverage of query (120 bits)
B2LS18 adenylosuccinate lyase (EC 4.3.2.2) from Ctenopharyngodon idella (see paper)
26% identity, 94% coverage of query (119 bits)
ADSL / P30566 adenylosuccinate lyase (EC 4.3.2.2) from Homo sapiens (see 3 papers)
PUR8_HUMAN / P30566 Adenylosuccinate lyase; ADSL; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Homo sapiens (Human) (see 14 papers)
P30566 adenylosuccinate lyase (EC 4.3.2.2) from Homo sapiens (see 5 papers)
27% identity, 94% coverage of query (119 bits)
ADE13 enzyme of adenine biosynthesis from Candida albicans (see paper)
26% identity, 94% coverage of query (118 bits)
PUR8_CHICK / P21265 Adenylosuccinate lyase; ADSL; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Gallus gallus (Chicken) (see paper)
26% identity, 94% coverage of query (116 bits)
ade13 / Q05911 Ade13 (EC 4.3.2.2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
26% identity, 94% coverage of query (115 bits)
Q05911 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
26% identity, 94% coverage of query (115 bits)
4eeiB / Q5NIQ1 Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with amp and succinate
27% identity, 75% coverage of query (114 bits)
5hw2A Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with fumaric acid
27% identity, 75% coverage of query (114 bits)
D3ZW08 adenylosuccinate lyase (EC 4.3.2.2) from Rattus norvegicus (see paper)
25% identity, 94% coverage of query (113 bits)
5vkwB / A0A1D8PT56 Crystal structure of adenylosuccinate lyase ade13 from candida albicans
25% identity, 94% coverage of query (109 bits)
ade8 / RF|NP_596735.1 adenylosuccinate lyase Ade8; EC 4.3.2.2 from Schizosaccharomyces pombe (see paper)
24% identity, 94% coverage of query (105 bits)
5nxaA Crystal structure of neanderthal adenylosuccinate lyase (adsl)in complex with its products aicar and fumarate
25% identity, 94% coverage of query (102 bits)
5eytA / G4VQX9 Crystal structure of adenylosuccinate lyase from schistosoma mansoni in complex with amp (see paper)
26% identity, 95% coverage of query (99.0 bits)
argH / BAC65282.1 argininosuccinate lyase from Burkholderia multivorans (see paper)
28% identity, 73% coverage of query (94.7 bits)
5nxaC / A0A384E0N4 Crystal structure of neanderthal adenylosuccinate lyase (adsl)in complex with its products aicar and fumarate (see paper)
25% identity, 80% coverage of query (94.0 bits)
5nx9C / A0A384E0N4 Crystal structure of neanderthal adenylosuccinate lyase (adsl) in complex with its products amp and fumarate (see paper)
24% identity, 94% coverage of query (93.6 bits)
5nxaB Crystal structure of neanderthal adenylosuccinate lyase (adsl)in complex with its products aicar and fumarate
27% identity, 75% coverage of query (92.0 bits)
Q9P870 argininosuccinate lyase (EC 4.3.2.1) from Agaricus bisporus (see paper)
27% identity, 75% coverage of query (78.6 bits)
A0A251UH44 fumarate hydratase (EC 4.2.1.2) from Helianthus annuus (see paper)
25% identity, 74% coverage of query (73.6 bits)
FUMC_SACS2 / P39461 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
P39461 fumarate hydratase (EC 4.2.1.2) from Saccharolobus solfataricus (see paper)
24% identity, 73% coverage of query (73.6 bits)
ARLY_NOSP7 / Q9LAE5 Argininosuccinate lyase; ASAL; ASL; Arginosuccinase; EC 4.3.2.1 from Nostoc punctiforme (strain ATCC 29133 / PCC 73102) (see paper)
Q9LAE5 argininosuccinate lyase (EC 4.3.2.1) from Nostoc sp. (see paper)
27% identity, 73% coverage of query (73.2 bits)
A0R4I6 adenylosuccinate lyase (EC 4.3.2.2) from Mycolicibacterium smegmatis (see paper)
27% identity, 96% coverage of query (73.2 bits)
FUM2 / Q9FI53 fumarase (EC 4.2.1.2) from Arabidopsis thaliana (see paper)
FUM2_ARATH / Q9FI53 Fumarate hydratase 2; AtFUM2; Fumarase 2; EC 4.2.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9FI53 fumarate hydratase (EC 4.2.1.2) from Arabidopsis thaliana (see 4 papers)
25% identity, 74% coverage of query (72.4 bits)
A0A251UZF1 fumarate hydratase (EC 4.2.1.2) from Helianthus annuus (see paper)
26% identity, 74% coverage of query (72.4 bits)
ARLY_COLLI / Q01592 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Columba livia (Rock dove) (see 2 papers)
28% identity, 74% coverage of query (71.2 bits)
ASL / P04424 argininosuccinate lyase (EC 4.3.2.1) from Homo sapiens (see 5 papers)
ARLY_HUMAN / P04424 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Homo sapiens (Human) (see 11 papers)
28% identity, 75% coverage of query (71.2 bits)
ARLY2_ANAPL / P24058 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin II; Delta-2 crystallin; EC 4.3.2.1 from Anas platyrhynchos (Mallard) (Anas boschas) (see 6 papers)
26% identity, 84% coverage of query (70.5 bits)
ARG7 / CAA09001.1 argininosuccinate lyase from Chlamydomonas reinhardtii (see paper)
25% identity, 84% coverage of query (70.5 bits)
1k7wD / P24058 Crystal structure of s283a duck delta 2 crystallin mutant (see paper)
26% identity, 84% coverage of query (69.3 bits)
ARLY1_CHICK / P02521 Delta-1 crystallin; Delta crystallin I from Gallus gallus (Chicken) (see 2 papers)
26% identity, 75% coverage of query (69.3 bits)
ARLY1_MELGA / Q7SIE0 Delta-1 crystallin; Delta crystallin I from Meleagris gallopavo (Wild turkey) (see paper)
26% identity, 75% coverage of query (68.2 bits)
ARLY1_ANAPL / P24057 Delta-1 crystallin; Delta crystallin I from Anas platyrhynchos (Mallard) (Anas boschas) (see 4 papers)
27% identity, 75% coverage of query (67.8 bits)
FUM1_ARATH / P93033 Fumarate hydratase 1, mitochondrial; AtFUM1; Fumarase 1; EC 4.2.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
P93033 fumarate hydratase (EC 4.2.1.2) from Arabidopsis thaliana (see 4 papers)
25% identity, 75% coverage of query (67.4 bits)
1hy0A Crystal structure of wild type duck delta 1 crystallin (eye lens protein)
27% identity, 75% coverage of query (66.2 bits)
2ptrA Crystal structure of escherichia coli adenylosuccinate lyase mutant h171a with bound adenylosuccinate substrate
25% identity, 93% coverage of query (65.9 bits)
2e9fB / Q5SLL0 Crystal structure of t.Th.Hb8 argininosuccinate lyase complexed with l-arginine
28% identity, 78% coverage of query (65.1 bits)
7lubB / P07954 Crystal structure of recombinant human fumarase in complex with d-2- amino-3-phosphono-propionic acid (see paper)
25% identity, 76% coverage of query (62.8 bits)
FH / P07954 fumarate hydratase monomer (EC 4.2.1.2) from Homo sapiens (see 7 papers)
FUMH_HUMAN / P07954 Fumarate hydratase, mitochondrial; Fumarase; HsFH; EC 4.2.1.2 from Homo sapiens (Human) (see 10 papers)
P07954 fumarate hydratase (EC 4.2.1.2) from Homo sapiens (see 3 papers)
25% identity, 76% coverage of query (62.4 bits)
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Lawrence Berkeley National Laboratory