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Searching for up to 100 curated homologs for GFF2298 FitnessBrowser__Phaeo:GFF2298 (815 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SarDH / Q64380 sarcosine dehydrogenase (EC 1.5.8.3) from Rattus norvegicus (see 10 papers)
SARDH_RAT / Q64380 Sarcosine dehydrogenase, mitochondrial; SarDH; EC 1.5.8.3 from Rattus norvegicus (Rat) (see 2 papers)
    42% identity, 100% coverage of query (655 bits)

SARDH / Q9UL12 sarcosine dehydrogenase (EC 1.5.8.3) from Homo sapiens (see 5 papers)
SARDH_HUMAN / Q9UL12 Sarcosine dehydrogenase, mitochondrial; SarDH; BPR-2; EC 1.5.8.3 from Homo sapiens (Human) (see 2 papers)
    41% identity, 100% coverage of query (649 bits)

mabO / Q8GAI3 4-methylaminobutyrate oxidase (demethylating) (EC 1.5.3.19) from Paenarthrobacter nicotinovorans (see 2 papers)
MABO1_PAENI / Q8GAI3 4-methylaminobutanoate oxidase (formaldehyde-forming); MABO; Demethylating gamma-N-methylaminobutyrate oxidase; Gamma-N-methylaminobutyrate oxidase 1; EC 1.5.3.19 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see 2 papers)
    39% identity, 100% coverage of query (575 bits)

PDPR_BOVIN / O46504 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial; PDPr from Bos taurus (Bovine) (see 2 papers)
    36% identity, 99% coverage of query (529 bits)

Q8NCN5 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase (EC 3.1.3.43) from Homo sapiens (see paper)
    36% identity, 98% coverage of query (525 bits)

DMGDH / Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 6 papers)
M2GD_HUMAN / Q9UI17 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Homo sapiens (Human) (see 2 papers)
Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 2 papers)
    37% identity, 94% coverage of query (508 bits)

Q5RKL4 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see paper)
    35% identity, 99% coverage of query (504 bits)

Q9DBT9 dimethylglycine dehydrogenase (EC 1.5.8.4) from Mus musculus (see paper)
    36% identity, 99% coverage of query (503 bits)

Dmgdh / Q63342 dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) from Rattus norvegicus (see 9 papers)
M2GD_RAT / Q63342 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Rattus norvegicus (Rat) (see 3 papers)
Q63342 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see 3 papers)
    35% identity, 99% coverage of query (501 bits)

4pabB / Q63342 Crystal structure of the precursor form of rat dmgdh complexed with tetrahydrofolate (see paper)
    35% identity, 100% coverage of query (501 bits)

dmg1 / Q9AGP8 dimethylglycine oxidase (EC 1.5.3.10) from Arthrobacter globiformis (see 7 papers)
DMGO_ARTGO / Q9AGP8 Dimethylglycine oxidase; DMGO; EC 1.5.3.10 from Arthrobacter globiformis (see 4 papers)
Q9AGP8 dimethylglycine oxidase (EC 1.5.3.10) from Arthrobacter globiformis (see paper)
    34% identity, 100% coverage of query (451 bits)

1pj6A / Q9AGP8 Crystal structure of dimethylglycine oxidase of arthrobacter globiformis in complex with folic acid (see paper)
    34% identity, 99% coverage of query (451 bits)

1pj7A Structure of dimethylglycine oxidase of arthrobacter globiformis in complex with folinic acid
    34% identity, 99% coverage of query (449 bits)

3gsiA Crystal structure of d552a dimethylglycine oxidase mutant of arthrobacter globiformis in complex with tetrahydrofolate
    34% identity, 99% coverage of query (446 bits)

Build an alignment

Build an alignment for GFF2298 and 14 homologs with ≥ 30% identity

Select sequences

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory