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Searching for up to 100 curated homologs for GFF2316 PGA1_c23480 putative D-beta-hydroxybutyrate dehydrogenase (257 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

A0A1E3M3N6 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acinetobacter baumannii (see paper)
6zzsD / A0A1E3M3N6 Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and 3-oxovalerate (see paper)
    40% identity, 97% coverage of query (175 bits)

6zzqA Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and acetoacetate
    40% identity, 97% coverage of query (175 bits)

Q5KST5 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas fragi (see 3 papers)
1wmbA / Q5KST5 Crystal structure of NAD dependent d-3-hydroxybutylate dehydrogenase (see paper)
BAD86668.1 D(-)-3-hydroxybutyrate dehydrogenase from Pseudomonas fragi (see paper)
    40% identity, 96% coverage of query (167 bits)

2ztlA Closed conformation of d-3-hydroxybutyrate dehydrogenase complexed with NAD+ and l-3-hydroxybutyrate
    40% identity, 96% coverage of query (167 bits)

5b4tA / D0VWQ0 Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and a substrate d-3- hydroxybutyrate (see paper)
    39% identity, 96% coverage of query (162 bits)

A8R3J3 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Ralstonia pickettii (see paper)
    39% identity, 96% coverage of query (162 bits)

3w8dA Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate
    39% identity, 96% coverage of query (162 bits)

3vdrA Crystal structure of d-3-hydroxybutyrate dehydrogenase, prepared in the presence of the substrate d-3-hydroxybutyrate and NAD(+)
    39% identity, 96% coverage of query (162 bits)

3vdqA Crystal structure of alcaligenes faecalis d-3-hydroxybutyrate dehydrogenase in complex with NAD(+) and acetate
    39% identity, 96% coverage of query (162 bits)

3sjuA / Q67G28 Hedamycin polyketide ketoreductase bound to NADPH (see paper)
    39% identity, 93% coverage of query (157 bits)

dpsE / Q54812 daunorubicin polyketide synthase reductase from Streptomyces peucetius (see paper)
    37% identity, 96% coverage of query (157 bits)

aknA / Q9L553 aclacinomycin polyketide synthase reductase from Streptomyces galilaeus (see paper)
    38% identity, 95% coverage of query (154 bits)

5yssB / A0A0D7LY80 Crystal structure of aminocaproic acid cyclase in complex with NAD (+) (see paper)
    36% identity, 97% coverage of query (152 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    34% identity, 96% coverage of query (150 bits)

snoaD / CAA12013.1 SnoaD from Streptomyces nogalater (see 3 papers)
    38% identity, 96% coverage of query (149 bits)

1x1tA / Q5KST5 Crystal structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas fragi complexed with NAD+ (see paper)
    38% identity, 96% coverage of query (143 bits)

5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    34% identity, 96% coverage of query (142 bits)

bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
    34% identity, 96% coverage of query (142 bits)

Q9AE70 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas putida (see 2 papers)
    34% identity, 97% coverage of query (142 bits)

2q2qD / Q9AE70 Structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida (see paper)
    34% identity, 97% coverage of query (142 bits)

jadE / Q56166 jadomycin biosynthesis oxidoreductase JadE from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see 2 papers)
    38% identity, 95% coverage of query (140 bits)

Q767A0 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acidovorax sp. (see paper)
    37% identity, 96% coverage of query (140 bits)

C7RM91 acetoacetyl-CoA reductase (EC 1.1.1.36) from Candidatus Accumulibacter phosphatis (see 2 papers)
    34% identity, 96% coverage of query (140 bits)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    33% identity, 96% coverage of query (140 bits)

ACT3_STRCO / P16544 Putative ketoacyl reductase; EC 1.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 2 papers)
    36% identity, 94% coverage of query (139 bits)

2rh4B / P16544 Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin (see paper)
    36% identity, 94% coverage of query (139 bits)

1xr3A Actinorhodin polyketide ketoreductase with NADP and the inhibitor isoniazid bound
    36% identity, 94% coverage of query (139 bits)

1w4zA Structure of actinorhodin polyketide (actiii) reductase
    36% identity, 94% coverage of query (139 bits)

2rh4A Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin
    36% identity, 94% coverage of query (139 bits)

3ak4A / G1K3P5 Crystal structure of nadh-dependent quinuclidinone reductase from agrobacterium tumefaciens
    35% identity, 96% coverage of query (138 bits)

1iy8A / Q9LBG2 Crystal structure of levodione reductase (see paper)
    36% identity, 95% coverage of query (137 bits)

lvr / Q9LBG2 levodione reductase monomer from Leifsonia aquatica (see 3 papers)
lvr / BAA95121.1 levodione reductase from Leifsonia aquatica (see paper)
    36% identity, 95% coverage of query (137 bits)

Q9LBG2 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum)
    36% identity, 95% coverage of query (137 bits)

hpsO / Q46N54 (S)-sulfopropanediol 2-dehydrogenase from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
    35% identity, 96% coverage of query (136 bits)

GALD_RHIME / Q92RN6 Probable galactose dehydrogenase GalD; EC 1.1.1.- from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
    37% identity, 96% coverage of query (135 bits)

C0IR58 aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Ralstonia sp. (see paper)
4bmsF / C0IR58 Short chain alcohol dehydrogenase from ralstonia sp. Dsm 6428 in complex with NADPH
    35% identity, 96% coverage of query (134 bits)

A0A5P1RES5 acetoacetyl-CoA reductase (subunit 1/2) (EC 1.1.1.36) from Neptunomonas concharum (see paper)
    31% identity, 96% coverage of query (134 bits)

6ihhA Crystal structure of rasadh f12 from ralstonia.Sp in complex with NADPH and a6o
    36% identity, 96% coverage of query (134 bits)

5ovlA Crystal structure of maba bound to NADP+ from m. Smegmatis
    35% identity, 95% coverage of query (134 bits)

5ovkA / P71534 Crystal structure maba bound to NADPH from m. Smegmatis (see paper)
    35% identity, 95% coverage of query (133 bits)

MABA_MYCS2 / P71534 3-oxoacyl-[acyl-carrier-protein] reductase MabA; 3-ketoacyl-acyl carrier protein reductase; Acetoacetyl-CoA reductase; Beta-ketoacyl-ACP reductase; Beta-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100; EC 1.1.1.36 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
P71534 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycolicibacterium smegmatis (see paper)
    35% identity, 95% coverage of query (133 bits)

tsaC / P94681 4-sulfobenzyl alcohol dehydrogenase subunit (EC 1.1.1.257) from Comamonas testosteroni (see paper)
TSAC_COMTE / P94681 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2; Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC; EC 1.2.1.62 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
    36% identity, 94% coverage of query (133 bits)

fabG1 / P9WGT2 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see paper)
MABA_MYCTU / P9WGT3 3-oxoacyl-[acyl-carrier-protein] reductase MabA; 3-ketoacyl reductase; 3-ketoacyl-acyl carrier protein reductase; Acetoacetyl-CoA reductase; Beta-ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; Mycolic acid biosynthesis A; EC 1.1.1.100; EC 1.1.1.36 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 10 papers)
P9WGT3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (see paper)
    34% identity, 95% coverage of query (132 bits)

phaB / Q3IZW0 (R)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.36) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see 3 papers)
    35% identity, 94% coverage of query (132 bits)

Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
    32% identity, 94% coverage of query (132 bits)

YfeF / b2426 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
ucpA / P37440 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli (strain K12) (see 6 papers)
    35% identity, 96% coverage of query (132 bits)

A1IG83 (R)-aminopropanol dehydrogenase (EC 1.1.1.75) from Rhodococcus erythropolis (see paper)
    34% identity, 98% coverage of query (132 bits)

1uznA / P9WGT3 Maba from mycobacterium tuberculosis (see paper)
    34% identity, 95% coverage of query (131 bits)

baiA3 / P07914 3α-hydroxysteroyl-CoA 3-dehydrogenase monomer (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 8 papers)
BAIA1_CLOSV / P07914 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 1/3; 3alpha-hydroxysteroid dehydrogenase 1/3; 3alpha-HSDH 1/3; Bile acid-inducible protein BaiA1; Bile acid-inducible protein BaiA3; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
    33% identity, 96% coverage of query (130 bits)

FABG_RICPR / P50941 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Rickettsia prowazekii (strain Madrid E)
P50941 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Rickettsia prowazekii (see paper)
    30% identity, 96% coverage of query (130 bits)

4wecA / A0QVJ7 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
    38% identity, 96% coverage of query (130 bits)

Q2PEN2 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Ralstonia pickettii (see 2 papers)
    33% identity, 96% coverage of query (130 bits)

phaB / BAC45231.1 3-keto-acyl-CoA reductase from Bacillus sp. INT005 (see paper)
    34% identity, 96% coverage of query (129 bits)

5h5xC / Q9KYM4 Crystal structure of nadh bound carbonyl reductase from streptomyces coelicolor
    38% identity, 96% coverage of query (129 bits)

mtmTII / Q194R2 MtmTII from Streptomyces argillaceus (see 2 papers)
    35% identity, 96% coverage of query (128 bits)

7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
    34% identity, 97% coverage of query (128 bits)

8dt1C / A0A1V2Y0M0 Crystal structure of a putative d-beta-hydroxybutyrate dehydrogenase from burkholderia cenocepacia j2315 in complex with NAD
    33% identity, 96% coverage of query (128 bits)

SILD_FORIN / Q94KL7 Secoisolariciresinol dehydrogenase; EC 1.1.1.331 from Forsythia intermedia (Border forsythia) (Forsythia suspensa x Forsythia viridissima) (see paper)
    34% identity, 97% coverage of query (127 bits)

6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
    33% identity, 95% coverage of query (127 bits)

3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
    34% identity, 96% coverage of query (127 bits)

phbB / P23238 acetoacetyl-CoA reductase subunit (EC 1.1.1.36) from Shinella zoogloeoides (see 2 papers)
PHAB_SHIZO / P23238 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Shinella zoogloeoides (Crabtreella saccharophila) (see paper)
    33% identity, 96% coverage of query (125 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    32% identity, 97% coverage of query (125 bits)

4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
    31% identity, 95% coverage of query (125 bits)

FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
    33% identity, 96% coverage of query (125 bits)

6ci9D / A0QP46 Rmm microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure (see paper)
    32% identity, 97% coverage of query (125 bits)

Pf1N1B4_412 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Pseudomonas fluorescens FW300-N1B4
    36% identity, 97% coverage of query (124 bits)

W5VJJ6 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens (see paper)
    33% identity, 96% coverage of query (124 bits)

W5VJT8 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
    33% identity, 96% coverage of query (124 bits)

RUMGNA_02133 / A7B3K3 chenodeoxycholate 3α-dehydrogenase (EC 1.1.1.392) from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see 4 papers)
3AHDP_RUMGV / A7B3K3 3alpha-hydroxysteroid dehydrogenase; 3alpha-HSDH; 3alpha-hydroxycholanate dehydrogenase (NADP(+)); NADP-dependent bile acid 3alpha-dehydrogenase; EC 1.1.1.-; EC 1.1.1.392 from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see paper)
    33% identity, 96% coverage of query (124 bits)

fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
    31% identity, 94% coverage of query (124 bits)

1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
    33% identity, 96% coverage of query (124 bits)

4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
    34% identity, 96% coverage of query (124 bits)

baiA2 / P19337 3α-hydroxysteroid dehydrogenase 2 (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 4 papers)
BAIA2_CLOSV / P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2; 3alpha-hydroxysteroid dehydrogenase 2; 3alpha-HSDH 2; Bile acid-inducible protein BaiA2; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase (EC 1.1.1.395) from [Clostridium] scindens (see paper)
    33% identity, 93% coverage of query (123 bits)

4is3C / P19337 Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (baia2) associated with secondary bile acid synthesis from clostridium scindens vpi12708 in complex with a putative NAD(+)-oh- adduct at 2.0 a resolution
    33% identity, 93% coverage of query (123 bits)

1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
    33% identity, 96% coverage of query (123 bits)

7krmC / A0A077GFB1 Putative fabg bound to nadh from acinetobacter baumannii
    33% identity, 96% coverage of query (123 bits)

3pk0B / A0QQJ6 Crystal structure of short-chain dehydrogenase/reductase sdr from mycobacterium smegmatis (see paper)
    35% identity, 97% coverage of query (122 bits)

6zzpA Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from psychrobacter arcticus complexed with NAD+ and 3-oxovalerate
    32% identity, 97% coverage of query (121 bits)

6zzoC / Q4FRT2 Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from psychrobacter arcticus complexed with NAD+ and acetoacetate (see paper)
    32% identity, 97% coverage of query (121 bits)

6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
    33% identity, 96% coverage of query (121 bits)

5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    32% identity, 96% coverage of query (120 bits)

FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    32% identity, 95% coverage of query (120 bits)

4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
    36% identity, 96% coverage of query (120 bits)

SDR / F1SWA0 zerumbone synthase (EC 1.1.1.326) from Zingiber zerumbet (see paper)
ZERSY_ZINZE / F1SWA0 Zerumbone synthase; EC 1.1.1.326 from Zingiber zerumbet (Shampoo ginger) (Amomum zerumbet) (see paper)
F1SWA0 zerumbone synthase (EC 1.1.1.326) from Zingiber zerumbet (see 2 papers)
    32% identity, 96% coverage of query (119 bits)

5u9pB / B4EEX4 Crystal structure of a gluconate 5-dehydrogenase from burkholderia cenocepacia j2315 in complex with NADP and tartrate
    33% identity, 96% coverage of query (119 bits)

2dtxA Structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt) in complex with d-mannose
    31% identity, 96% coverage of query (119 bits)

2dteA / Q9HK51 Structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt) in complex with nadh (see paper)
    31% identity, 96% coverage of query (119 bits)

7emgB / A0A0G8B235 Carbonyl reductase variant 4 (r123c/l209p/f183y/v61k) from serratia marcescens complexed with NADP+ (see paper)
    31% identity, 95% coverage of query (119 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    32% identity, 97% coverage of query (118 bits)

3uf0A / C5BY10 Crystal structure of a putative NAD(p) dependent gluconate 5- dehydrogenase from beutenbergia cavernae(efi target efi-502044) with bound NADP (low occupancy)
    35% identity, 97% coverage of query (117 bits)

7djsD / A0A554HE32 Crystal structure of isopiperitenol dehydrogenase from pseudomonas aeruginosa complexed with NAD
    35% identity, 82% coverage of query (117 bits)

xecD / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.268) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 5 papers)
HCDR1_XANP2 / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase; R-HPCDH; 2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase; Aliphatic epoxide carboxylation component III; Epoxide carboxylase component III; RHPCDH1; EC 1.1.1.268 from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 7 papers)
Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268) from Xanthobacter autotrophicus (see 4 papers)
2cfcA / Q56840 Structural basis for stereo selectivity in the (r)- and (s)-hydroxypropylethane thiosulfonate dehydrogenases (see paper)
    33% identity, 95% coverage of query (117 bits)

2ekpA / Q53W82 Structure of tt0495 protein from thermus thermophilus (see paper)
    33% identity, 95% coverage of query (117 bits)

Build an alignment

Build an alignment for GFF2316 and 93 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

4qecA / I6ZQW6 Elxo with NADP bound (see paper)
    28% identity, 95% coverage of query (116 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    32% identity, 95% coverage of query (116 bits)

1edoA / Q93X62 The x-ray structure of beta-keto acyl carrier protein reductase from brassica napus complexed with NADP+ (see paper)
    35% identity, 94% coverage of query (116 bits)

8hsaA / Q8YIN7 Brucella melitensis 7-alpha-hydroxysteroid dehydrogenase mutant: 1-53 truncation/m196i/i258m/k262t-NAD+
    34% identity, 88% coverage of query (116 bits)

phbB / D3UAK7 hydroxyvaleryl-CoA reductase (EC 1.1.1.36) from Cupriavidus necator (see 2 papers)
PHAB_CUPNH / P14697 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see 4 papers)
P14697 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); acetoacetyl-CoA reductase (EC 1.1.1.36) from Cupriavidus necator (see 3 papers)
    30% identity, 96% coverage of query (115 bits)

PHAB_SYNY3 / P73826 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    34% identity, 96% coverage of query (115 bits)

3vzsB / P14697 Crystal structure of phab from ralstonia eutropha in complex with acetoacetyl-coa and NADP (see paper)
    31% identity, 95% coverage of query (115 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory