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Searching for up to 100 curated homologs for GFF2364 FitnessBrowser__WCS417:GFF2364 (335 a.a.)

Found high-coverage hits (≥70%) to 32 curated proteins.

Removed hits that are identical to the query, leaving 31

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

THPA_MYCS2 / A0QYB5 D-threitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    38% identity, 87% coverage of query (177 bits)

4rsmA / A0QYB5 Crystal structure of carbohydrate transporter msmeg_3599 from mycobacterium smegmatis str. Mc2 155, target efi-510970, in complex with d-threitol (see paper)
    37% identity, 79% coverage of query (164 bits)

XYPA_MYCS2 / A0QYB3 Xylitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    38% identity, 83% coverage of query (163 bits)

4rs3A / A0QYB3 Crystal structure of carbohydrate transporter a0qyb3 from mycobacterium smegmatis str. Mc2 155, target efi-510969, in complex with xylitol (see paper)
    38% identity, 79% coverage of query (160 bits)

5hkoA Crystal structure of abc transporter solute binding protein msmeg_3598 from mycobacterium smegmatis str. Mc2 155, target efi-510969, in complex with l-sorbitol
    38% identity, 79% coverage of query (160 bits)

PS417_11885 Inositol transport system sugar-binding protein from Pseudomonas simiae WCS417
    35% identity, 88% coverage of query (155 bits)

4yo7A / Q9KAG4 Crystal structure of an abc transporter solute binding protein (ipr025997) from bacillus halodurans c-125 (bh2323, target efi- 511484) with bound myo-inositol
    32% identity, 78% coverage of query (136 bits)

7e7mC / Q8E283 Crystal structure analysis of the streptococcus agalactiae ribose binding protein rbsb
    34% identity, 71% coverage of query (115 bits)

RBSB_BACSU / P36949 Ribose import binding protein RbsB from Bacillus subtilis (strain 168) (see 2 papers)
    30% identity, 77% coverage of query (103 bits)

Build an alignment

Build an alignment for GFF2364 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

4rxmA Crystal structure of periplasmic abc transporter solute binding protein a7jw62 from mannheimia haemolytica phl213, target efi-511105, in complex with myo-inositol
    29% identity, 72% coverage of query (100 bits)

4rxmB Crystal structure of periplasmic abc transporter solute binding protein a7jw62 from mannheimia haemolytica phl213, target efi-511105, in complex with myo-inositol
    29% identity, 72% coverage of query (100 bits)

4irxA / A0A0H3C834 Crystal structure of caulobacter myo-inositol binding protein bound to myo-inositol (see paper)
    32% identity, 75% coverage of query (97.8 bits)

TC 3.A.1.2.21 / B8H228 Inositol ABC transporter, periplasmic inositol-binding protein IbpA, component of The myoinositol (high affinity)/ D-ribose (low affinity) transporter IatP/IatA/IbpA. The structure of IbpA with myoinositol bound has been solved from Caulobacter crescentus (strain NA1000 / CB15N)
    33% identity, 71% coverage of query (97.8 bits)

8fxuA / D9TSJ1 Thermoanaerobacter thermosaccharolyticum periplasmic glucose-binding protein glucose complex: badan conjugate attached at f17c (see paper)
    32% identity, 77% coverage of query (95.5 bits)

HSERO_RS11480 D-ribose ABC transporter, substrate-binding component RbsB from Herbaspirillum seropedicae SmR1
    30% identity, 84% coverage of query (94.7 bits)

5kwsA / Q8D072 Crystal structure of galactose binding protein from yersinia pestis in the complex with beta d glucose
    30% identity, 77% coverage of query (92.4 bits)

MglB / b2150 D-galactose/methyl-galactoside ABC transporter periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 43 papers)
MglB / P0AEE5 D-galactose/methyl-galactoside ABC transporter periplasmic binding protein from Escherichia coli (strain K12) (see 42 papers)
MGLB_ECOLI / P0AEE5 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.3 / P0AEE5 D-galactose-binding periplasmic protein DGAL aka MglB aka B2150, component of Galactose/glucose (methyl galactoside) porter from Escherichia coli (see 10 papers)
    30% identity, 84% coverage of query (87.4 bits)

P23905 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    30% identity, 84% coverage of query (85.5 bits)

2gbpA / P0AEE5 Sugar and signal-transducer binding sites of the escherichia coli galactose chemoreceptor protein (see paper)
    29% identity, 77% coverage of query (83.2 bits)

RbsB / b3751 ribose ABC transporter periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 25 papers)
RbsB / P02925 ribose ABC transporter periplasmic binding protein from Escherichia coli (strain K12) (see 25 papers)
RBSB_ECOLI / P02925 Ribose import binding protein RbsB from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.2.1 / P02925 RbsB aka RBSP aka PRLB aka B3751, component of Ribose porter from Escherichia coli (see 11 papers)
rbsB / GB|AAC76774.1 D-ribose-binding periplasmic protein; EC 3.6.3.17 from Escherichia coli K12 (see 11 papers)
    29% identity, 76% coverage of query (82.8 bits)

2qw1A Glucose/galactose binding protein bound to 3-o-methyl d-glucose
    29% identity, 77% coverage of query (82.8 bits)

3ga5A X-ray structure of glucose/galactose receptor from salmonella typhimurium in complex with (2r)-glyceryl-beta-d-galactopyranoside
    29% identity, 77% coverage of query (80.9 bits)

1gcaA The 1.7 angstroms refined x-ray structure of the periplasmic glucose(slash)galactose receptor from salmonella typhimurium
    29% identity, 77% coverage of query (80.9 bits)

8fxtA Escherichia coli periplasmic glucose-binding protein glucose complex: acrylodan conjugate attached at w183c
    29% identity, 77% coverage of query (78.6 bits)

4z0nA / D1AWX5 Crystal structure of a periplasmic solute binding protein (ipr025997) from streptobacillus moniliformis dsm-12112 (smon_0317, target efi- 511281) with bound d-galactose
    28% identity, 77% coverage of query (76.6 bits)

RALBP_PSEAE / Q9I2F8 D-ribose/D-allose-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    27% identity, 85% coverage of query (76.3 bits)

TC 3.A.1.2.5 / P25548 CVE1 aka ChvE aka ATU2348 aka AGR_C_4267, component of Multiple sugar (arabinose, xylose, galactose, glucose, fucose) putative porter from Agrobacterium tumefaciens (see 4 papers)
    26% identity, 78% coverage of query (61.6 bits)

3urmA / P25548 Crystal structure of the periplasmic sugar binding protein chve (see paper)
    26% identity, 78% coverage of query (61.2 bits)

3uugA Crystal structure of the periplasmic sugar binding protein chve
    26% identity, 78% coverage of query (61.2 bits)

AscG / VIMSS10478968 AscG regulator of Beta-glucosides utilization; Cellobiose utilization, effector Cellobiose-6-phosphate; Beta-glucoside-6-phosphate (repressor) from Erwinia amylovora ATCC 49946
    27% identity, 70% coverage of query (58.5 bits)

4wwhA / A0QT42 Crystal structure of an abc transporter solute binding protein (ipr025997) from mycobacterium smegmatis (msmeg_1704, target efi- 510967) with bound d-galactose
    26% identity, 78% coverage of query (50.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory