Searching for up to 100 curated homologs for GFF2418 FitnessBrowser__Phaeo:GFF2418 (134 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

EPI_CERS4 / Q3IZP4 Ethylmalonyl-CoA/methylmalonyl-CoA epimerase; EC 5.1.99.-; EC 5.1.99.1 from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides) (see paper)
    93% identity, 100% coverage of query (254 bits)

MCEE / Q96PE7 methylmalonyl CoA epimerase (EC 5.1.99.1) from Homo sapiens (see 4 papers)
MCEE_HUMAN / Q96PE7 Methylmalonyl-CoA epimerase, mitochondrial; DL-methylmalonyl-CoA racemase; EC 5.1.99.1 from Homo sapiens (Human) (see 2 papers)
Q96PE7 methylmalonyl-CoA epimerase (EC 5.1.99.1) from Homo sapiens (see 3 papers)
    67% identity, 99% coverage of query (169 bits)

6qh4C / Q96PE7 Crystal structure of human methylmalonyl-coa epimerase (mcee) p.Arg143cys variant
    65% identity, 99% coverage of query (163 bits)

MCE_PYRHO / O58010 Methylmalonyl-CoA epimerase; DL-methylmalonyl-CoA racemase; EC 5.1.99.1 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see 2 papers)
    39% identity, 98% coverage of query (89.0 bits)

GI:18042134 / Q8VQN0 methylmalonyl CoA epimerase subunit (EC 5.1.99.1) from Propionibacterium freudenreichii subsp. shermanii (see 4 papers)
    36% identity, 96% coverage of query (85.1 bits)

3oa4A / Q9KCV1 Crystal structure of hypothetical protein bh1468 from bacillus halodurans c-125
    39% identity, 96% coverage of query (84.0 bits)

6wf7A / Q9L2C2 Methylmalonyl-coa epimerase in complex with methylmalonyl-coa and nh4+ (see paper)
    35% identity, 97% coverage of query (75.5 bits)

6wf6A Streptomyces coelicolor methylmalonyl-coa epimerase
    35% identity, 97% coverage of query (75.5 bits)

6wfhA Streptomyces coelicolor methylmalonyl-coa epimerase substrate complex
    35% identity, 97% coverage of query (75.5 bits)

6xbqA Streptomyces coelicolor methylmalonyl-coa epimerase in complex with carboxy-carba(dethia)-coa
    35% identity, 97% coverage of query (75.5 bits)

6wfiA Methylmalonyl-coa epimerase in complex with 2-nitronate-propionyl-coa
    35% identity, 97% coverage of query (75.5 bits)

6xbtA Streptomyces coelicolor methylmalonyl-coa epimerase (q60a) in complex with 2-nitronate-propionyl-coa
    35% identity, 97% coverage of query (74.3 bits)

K7SKA8 methylmalonyl-CoA epimerase (EC 5.1.99.1) from Acidipropionibacterium acidipropionici (see paper)
    37% identity, 96% coverage of query (73.2 bits)

Msed_0639 / A4YEG2 methylmalonyl-CoA epimerase monomer (EC 5.1.99.1) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 2 papers)
A4YEG2 methylmalonyl-CoA epimerase (EC 5.1.99.1) from Metallosphaera sedula (see paper)
    34% identity, 96% coverage of query (71.2 bits)

mcee / A9WGS0 methylmalonyl-CoA epimerase (EC 5.1.99.1) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
    37% identity, 99% coverage of query (70.5 bits)

epi / CAJ91089.1 methylmalonyl-CoA epimerase from Sorangium cellulosum (see paper)
    33% identity, 96% coverage of query (65.1 bits)

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Build an alignment for GFF2418 and 16 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

Q97H22 lactoylglutathione lyase (EC 4.4.1.5) from Clostridium acetobutylicum (see paper)
    26% identity, 96% coverage of query (47.8 bits)

2qh0A / Q97H22 Crystal structure of a glyoxalase from clostridium acetobutylicum
    26% identity, 96% coverage of query (47.8 bits)

P0A0T3 lactoylglutathione lyase (EC 4.4.1.5) from Neisseria meningitidis (see paper)
    31% identity, 85% coverage of query (43.1 bits)

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